Stipple Launches with $100M for Novel Oncology Targets
Stipple, a new biotech focused on oncology, announced a $100 million Series A financing round to pursue novel, historically undruggable cancer targets. The round was led by top‑tier venture firms and includes strategic commitments from several large pharmaceutical partners. Stipple’s founding team combines deep academic expertise with prior drug‑development successes, positioning the company to accelerate early‑stage discovery. The capital will fund platform technology development, preclinical programs, and collaborative validation studies.
April 7, 1991: Compton Gamma Ray Observatory Is Deployed
NASA’s Compton Gamma Ray Observatory (CGRO) was deployed from Space Shuttle Atlantis on April 7, 1991, marking the launch of the agency’s third Great Observatory focused on gamma‑ray astronomy. A thermal‑blanket snag that prevented the high‑gain antenna from opening required an unscheduled...
Optimization of Brain-Permeable SGK1 Inhibitors for Neurodegenerative Diseases
Jiangsu and Shanghai Hengrui Pharmaceuticals have patented selective Nav1.8 sodium‑channel blockers that alleviate inflammatory and neuropathic pain in rodent studies and are slated for IND‑enabling toxicology this year, aiming for Phase I trials in 2027. Parallel research highlights chronic inflammation’s role...
Dectisomes Show Potent Activity Against High-Priority Fungal Pathogens
Jiangsu and Shanghai Hengrui patented selective Nav1.8 blockers that show potent analgesic effects with minimal off‑target activity. New research links chronic inflammation in the bone‑marrow niche to epigenetic reprogramming of hematopoietic stem cells, suggesting early‑intervention strategies for leukemia prevention. Infinimmune...
Suzhou Spring-Sea Bio-Pharmaceuticals Identifies New GLP-1R Agonists
Suzhou Spring‑Sea Bio‑Pharmaceuticals announced the discovery of a novel series of glucagon‑like peptide‑1 receptor (GLP‑1R) agonists that demonstrate high potency and prolonged half‑life in pre‑clinical models. The compounds show superior glucose‑lowering efficacy compared with existing market leaders and exhibit favorable...
Upstart Aria Networks Unveils AI‑Native Networking Platform For The AI Factory Era
Aria Networks, a Palo Alto startup, announced the general availability of its AI‑native networking platform designed for the emerging AI factory era. The solution delivers ultra‑fine telemetry—up to 10,000 times more granular than traditional tools—and automatically closes the loop to...
Acadia Pharmaceuticals Presents GPR88 Agonists
Researchers at Jiangsu and Shanghai Hengrui have patented Nav1.8 blockers that deliver strong analgesic effects while sparing off‑target channels, opening a new avenue for chronic pain therapy. Parallel studies reveal that chronic inflammation can reprogram hematopoietic stem cells, driving early...
Colorado's New Speed Cameras Can't Be Outsmarted by Waze
Colorado has activated an automated speed‑camera system on a five‑mile stretch of I‑25 south of Fort Collins, using paired cameras to calculate average speed rather than a single radar snapshot. The program, part of CDOT’s Speed Enforcement initiative, began enforcement on...
Orexin OX2 Receptor Agonists Disclosed in Vertex Pharmaceuticals Patent
Vertex Pharmaceuticals has filed a patent covering a new series of orexin OX2‑receptor agonists, marking the company’s first public foray into sleep‑modulating therapeutics. The disclosed molecules feature distinct heterocyclic cores and enhanced blood‑brain barrier penetration, aiming for improved potency and...
Starfish Closes $100M+ Series B
Starfish Space announced a Series B round exceeding $100 million, led by Point72 Ventures and co‑led by Activate Capital and Shield Capital, with participation from several other investors. The capital will fund the company’s first full‑scale Otter mission, expand production capacity,...
For Everyday Business Tasks, This $200 Refurbished MacBook Air Gets It Done
A refurbished 2017 MacBook Air is on sale for $199.97, a steep discount from its $999 original price. The laptop features a 1.8 GHz Intel Core i5 processor, 8 GB RAM, and a 128 GB SSD, which are adequate for email, documents, spreadsheets,...
Holiday Notice
Jiangsu and Shanghai Hengrui Pharmaceuticals have patented selective Nav1.8 sodium‑channel blockers that demonstrate potent analgesic effects with minimal off‑target activity, opening a new avenue for chronic pain treatment. Parallel research highlights how chronic inflammation reshapes the bone‑marrow microenvironment, driving hematopoietic...
Two Boxes Raises $3.2M to Scale AI Returns Platform
Two Boxes, an AI‑powered returns platform, secured $3.2 million in new financing led by Assembly Ventures, bringing its total capital to $13 million. The funding will accelerate product development and push the company deeper into enterprise retail, direct‑to‑consumer and B2B...
Chengdu Kanghong Pharmaceutical Patents New Lipoprotein(a)-Lowering Agents
Researchers at Jiangsu and Shanghai Hengrui have patented selective Nav1.8 sodium‑channel blockers that relieve neuropathic and inflammatory pain in rodents without impairing motor function, with filings in China and the United States and IND‑enabling work slated for later this year....
Next-Generation Anti-CD30 ADC Outperforms Brentuximab Vedotin
Biopharma X unveiled a next‑generation anti‑CD30 antibody‑drug conjugate that demonstrated superior efficacy and tolerability compared with the established therapy brentuximab vedotin. In preclinical models, the ADC achieved deeper tumor regressions and a broader therapeutic window, driven by an optimized linker...
Starfish Space Raises More than $100 Million
Starfish Space announced a Series B round that raised over $100 million, led by Point72 Ventures and co‑led by Activate Capital and Shield Capital. The capital will be used to scale production of its Otter line of satellite‑servicing spacecraft and to hire...
ACH Is Thriving, and Banks Are Struggling to Keep Pace
Automated Clearing House (ACH) remains the dominant U.S. payment rail, with volume accelerating due to a government mandate eliminating paper checks and expanding Same‑Day ACH windows. While FedNow and RTP push real‑time payments, ACH still handles bulk payroll, government disbursements,...
Tennant Rolls Out X16 SWEEP for Round-the-Clock Autonomous Sweeping
Tennant announced the X16 SWEEP, its first autonomous floor‑sweeping robot from a major cleaning brand, targeting warehouses, logistics hubs and light‑manufacturing sites. Powered by Brain Corp’s BrainOS, the machine combines AI‑driven path planning, visual intelligence and a DustShield system that...
Monolithic Bidirectional GaN Switch-Based Buck-Boost Converter
A novel condensed buck‑boost (CoBB) converter replaces the traditional multilevel flying‑capacitor architecture with a monolithic GaN bidirectional switch (BDS), cutting active device count and improving efficiency. The prototype, built with Transphorm (Renesas) GaN BDS devices, delivered over 95% efficiency at...
Nrf2 Activator Counteracts Atopic Dermatitis Pathology
Researchers have identified a novel Nrf2 activator that mitigates key pathological features of atopic dermatitis in preclinical studies. The compound suppresses oxidative stress and downregulates pro‑inflammatory cytokines, leading to restored skin barrier integrity in murine models. Data presented at the...
BPFDoor Variants Hide with Stateless C2 and ICMP Relay Tactics
Rapid7 Labs identified seven new BPFDoor variants that embed Berkeley Packet Filter code in the Linux kernel, allowing the backdoor to remain hidden in telecom environments. The malware now employs a stateless command‑and‑control model, treating the source of a specially...
Advanced Mobile Phone Detection & Geolocation Solutions for UAVs
Smith Myers, a UK‑based specialist in wireless technologies, has joined Unmanned Systems Technology’s Gold supplier network with its ARTEMIS family of mobile‑phone detection and geolocation systems for UAVs. The flagship ARTEMIS can locate 2G devices up to 35 km and LTE...
Boehringer Ingelheim’s Confident New Leap in the Obesity Market
Boehringer Ingelheim has created a new obesity and liver health unit led by senior vice president Vani Manja, targeting a rapidly expanding GLP‑1 market that could reach 25 million U.S. patients by 2030. The company’s pipeline features the dual glucagon/GLP‑1 agonist...
Bankruptcy and Restructuring Company Stretto Launches New Research Platform
Stretto, a specialist bankruptcy and restructuring firm, announced the launch of its Research Suite, a new platform designed to surface and compare bankruptcy documents across jurisdictions. The service aggregates court filings, DIP financing agreements, and plan documents, providing a searchable...
Natter Raises $23M to Replace Enterprise Surveys with AI-Moderated Video Conversations
London‑based Natter announced a $23 million Series A round led by Renegade Partners to accelerate its AI‑moderated video conversation platform. The technology replaces traditional employee surveys with seven‑minute video sessions that generate over 1,000 words of structured insight, compared with roughly ten...
Whose Water Powers the Cloud? Data Centers and the Right to Water in Johor
Johor, Malaysia, has become Southeast Asia’s fastest‑growing data‑center hub, with capacity reaching about 5.8 GW by mid‑2025—almost double the previous year. The rapid expansion has sparked a water‑use crisis, as medium‑sized centers consume roughly 110 million gallons annually and mega‑centers up to...
Photonics Emerges as AI’s Next Data Bottleneck
From Copper to Light: The Critical Bottleneck Reshaping AI Infrastructure 🧵 Photonics is becoming one of the most important AI bottlenecks. Compute is scaling fast, but moving data between GPUs is now the harder problem. Copper hits power and bandwidth limits....
EY’s Agentic AI Pivot – A Watershed Moment for Audit Quality?
EY is rolling out an enterprise‑scale, multi‑agent AI framework across 160,000 audit engagements, embedding Microsoft Azure, Foundry and Fabric into its EY Canvas platform. The system processes about 1.4 trillion journal‑entry lines annually, moving the profession toward 100 % population testing and...
Docker Flaw (CVE-2026-34040) Lets Attackers Bypass Security Controls and Take Over Hosts
Researchers at Cyera disclosed CVE‑2026‑34040, a critical Docker Engine flaw that lets attackers bypass authorization plugins by sending API requests larger than 1 MB. The daemon processes the full payload while the plugin sees a truncated request, enabling creation of privileged...
Instagram Now Lets Creators Tag Affiliate Links Directly in Reels
Instagram is rolling out a new feature that lets creators tag shoppable products directly in Reels, supporting up to 30 items per video. Creators can add products by pasting affiliate URLs or selecting items from a brand’s Meta commerce catalog,...
Federal Agencies Turn to AI to Transform Contact Centers at Scale
Federal agencies, led by the U.S. Postal Service and the Department of Labor, are deploying Salesforce’s Agentforce AI platform to overhaul contact‑center operations. By automating tier‑0 inquiries and providing real‑time assistance, AI is closing call‑handling gaps without adding headcount. Both...
China Issues New E-Commerce Guidelines Following Pressure From the EU
China released new e‑commerce guidelines a week after an EU delegation raised concerns in Beijing about counterfeit and unsafe goods flowing to Europe. The rules, crafted with multiple agencies, aim to align Chinese cross‑border platforms with international safety standards and...
Government Confirms £195m Green Heat Network Funding for England and Wales
The UK government has earmarked £195 million for the Green Heat Network Fund, extending the grant programme to include Wales for the first time. The funding will back new heat‑network projects, upgrades, and integration of renewable sources such as biomass, solar...
The Trolleybuses Returns to Tallinn
Tallinn’s trolleybus fleet renewal is now underway, with the first of 40 new vehicles completed and ready for testing. The new fleet, comprising 12‑metre and 18‑metre Škoda‑SOR models, will replace the aging 49‑bus fleet delivered between 2002 and 2010. Deliveries...
Don’t Hardcode Content
A client’s outbound communications were locked in Visualforce emails and Apex‑hardcoded SMS, making updates painful. The consultant migrated the emails to Lightning Email Templates (LET) with Enhanced Letterheads, simplifying edits to a Word‑like experience. Order details were moved to a...
Zero‑click Grafana AI Attack Can Enable Enterprise Data Exfiltration
Security researchers have uncovered GrafanaGhost, a chained exploit that leverages indirect prompt injection in Grafana’s AI dashboards to exfiltrate sensitive enterprise data without user authentication. The attack persists malicious prompts, tricks the AI model into generating outbound image requests, and...
Ahold Delhaize USA Introduces Pay by Bank Partnership with Fiserv
Ahold Delhaize USA has broadened its partnership with payments‑technology leader Fiserv to roll out Pay by Bank across the e‑commerce sites and mobile apps of The GIANT Company, Giant Food and Stop & Shop. The new option lets shoppers link...
The Works CEO: How the Brand Is Betting Big on Bricks-and-Mortar
The Works, a UK discount retailer with more than 500 high‑street stores, announced it will abandon its ecommerce platform and double‑down on a store‑led strategy. In‑store sales already account for over 90% of revenue and like‑for‑like sales are up 3.3%...
Affiliates, To Stay Relevant, Move Beyond Mere Execution
Artificial intelligence is rapidly automating routine tasks in affiliate marketing, from matching affiliates to offers to generating performance dashboards. While AI boosts efficiency, it also exposes limits, requiring human oversight to correct errors and prevent fraud. The article argues that...
Flamel.ai Launches Luna to Fix Franchise Marketing Execution
Flamel.ai unveiled Luna, an AI‑powered agent that executes, analyzes, and optimizes franchise marketing across all locations, completing a broader platform expansion that unifies paid media, local SEO, social and review tools. The system lets corporate teams build a single campaign...
Over 1,000 Exposed ComfyUI Instances Targeted in Cryptomining Botnet Campaign
Security researchers have identified a campaign that scans cloud IP ranges for exposed ComfyUI instances—a popular Stable Diffusion UI—and hijacks them for cryptocurrency mining and proxy botnet operations. The Python‑based scanner exploits a misconfiguration in custom nodes to achieve unauthenticated...
KWh Analytics to Reward Hail-Ready Solar Projects with Lower Insurance Costs
kWh Analytics has launched a data‑sharing pilot that lets solar developers provide real‑time tracker stow performance to insurers. By incorporating metrics such as 70° or 75° stow angles and heat‑tempered glass, the program demonstrates that resilient designs can slash projected...
Lucozade Woos ‘Believers’ for Grafruitti Flavour Relaunch
Lucozade is re‑launching its Grafruitti flavour, first introduced as a limited edition in 2015, with a community‑centric campaign aimed at the brand’s self‑identified “Believers.” The rollout, crafted by We Are Social, began with teaser posts and a logo swap before...
The Terraform Scaling Problem: When Infrastructure-as-Code Becomes Infrastructure-as-Complexity
Terraform dominates IaC with 76% market share and 90% cloud adoption, but scaling introduces severe state file contention, module sprawl, long plan times, and drift that double failure rates. Organizations with over 500 resources see plan operations stretch to 15‑30...
Awaiting AI to Real-Time Fact
I’m counting down to the day Grok starts fact-checking every deranged viral lie in real time & curb-stomps the poster with receipts. Germany & Japan would still be poor today if we had hung every “war criminal” We are a nation built...
Neutral Atoms Become Second‑largest Qubit Platform by Company Count
neutral atoms are now officially the second most competitive qubit platform out there in terms of numbers of companies… with at least one more company in stealth. https://t.co/XoL1yY1JY2
In the Face of Tariffs, FDA-Approved Drug Manufacturing Deals Are Shifting to Europe
US contract‑manufacturing (CM) deals for FDA‑approved drugs fell sharply last year, marking the biggest decline in five years. Despite a 15% import tariff on European pharmaceuticals, biopharma firms are increasingly outsourcing US‑bound production to European facilities, especially in Germany. By...
Anthropic Secures TPU Capacity, Signaling Compute Diversification
.@Anthropic inks deal with @Google, @Broadcom for TPU capacity https://t.co/FCwUyLMN3c >> Congrats. Compute restrictions are real and supplier diversity is critical. Inflection point for Google TPUs going beyond @GoogleCloud. #NextGenApps by @LDignan
US Archives Release Nazi Party Records for Public Search
The US National Archives opened up Nazi party member cards and @DIEZEIT made them searchable so German families can examine their heritage. MAGA be aware: Your descendants will ask what you did in fascist America. They will judge you. https://t.co/Vhn8osAgSE
How Can Malaysia Leverage AI for Growth and Not See It as a Threat?
Malaysia stands at a crossroads as AI reshapes sectors from healthcare to manufacturing. While the global AI market is forecast to reach $2.6 trillion by 2032, only 13% of Malaysian organisations feel prepared to adopt the technology. A survey shows 62%...
