Nanophotonic Chips Finally Make the Proteome Visible
We sequence genomes and map transcriptomes with ease. Why is the proteome still invisible? Proteins are where biology actually happens. But until now, we have lacked the tools to read them at scale. @jendionne and her team are building nanophotonic chips that turn proteins into readable signals. Not by inference, but by directly measuring their molecular fingerprints. We sat down with her to learn more about her vision for protein sequencing. Article linked below SynBioBeta 2026 is May 4-7th in San Jose, California, you can learn more about the conference and get your tickets here: https://t.co/96IRAmgbEi “Pumpkinseed reads directly from molecular vibrations, requiring no catalog and no prior knowledge of what it is looking for.” If this works at scale, it becomes the missing data layer for AI-driven biology. The foundation for virtual cells. The next infrastructure moment after the Human Genome Project. This is exactly the kind of work that changes industries. And these are exactly the kinds of people you want to meet in person. Because relationships are built in the room. Deals happen in the room. Breakthroughs happen in the room. Excited to have Jennifer Dionne join us at #SynBioBeta2026. Visit the SynBioBeta website to read the full article linked below: https://t.co/FF2ciWs84E
Roku's Search Mismatches NBA and WNBA Apps
Love that I can search “NBA” on Roku and the “WNBA” app doesn’t show up, but if i search “WNBA,” the “NBA” app does show up. That just doesn’t make sense, grammatically.
BrightNight, Lydian Acquire US Assets; ILOS Upsizes Euro Credit
ROUNDUP: IPPs BrightNight, Lydian acquire US portfolios, ILOS Projects upsizes European credit facility #energysky -- via Energy Storage News: https://t.co/k1mwJQh9O6
Audit Your Desk Setup for Healthier, More Productive Work
Here are 5 epic prompts to use with ChatGPT's new image generator. It's the most powerful image generator on the market, so let's use it to our advantage. Save this one 📌 WORK SETUP AUDIT: upload a photo of your desk...
PE's SaaS Cash‑flow Predictability Now in Question
Good primer from @DavidSacks on private equity ownership of SaaS (software) firms based on cash flows whose predictability used to be certain but now is in question. A topic which @maxwiethe have been covering a lot on our show on...
Government Policy Essential to Guide AI’s Complex Societal Impact
If you believe that AI is going to have a big impact on work and life, the only real tool for mitigating bad impacts and channeling usage for good will be government policy And that policy will be complicated: AI will...
Leadership Now Needs AI as a Core Teammate
The End of the Middleman: Why Modern Leadership Requires an AI Teammate by @Timothy_Hughes https://t.co/40RPirrmDX @DLAIgnite #SocialSelling #DigitalSelling #Sales #SalesTips #SalesLeader #Salesforce #SalesEnablement #Marketing #Leadership #ArtificialIntelligence #TechNews https://t.co/WleG16CfLp
Tesla's FSD Beats Huawei ADAS in China Test
In China they're running side by side Tesla FSD comp to Huawei ADAS and the results speak for themselves. $TSLA
AI Hiring Laws Become Liability, Not Compliance
There Are No Rules. There Are Only Lawyers. Employers now face a patchwork of state, local, and federal requirements governing AI in employment decisions, with Illinois, Colorado, and New York City leading enforcement. Illinois's House Bill 3773, effective January 2026,...
GStack v1.13 Enables Cross‑Modal Synthesis with GPT‑5.5
GStack v1.13 shipped - simple feature, I'm spending a lot more time using GPT-5.5 with Conductor and so I realized I sometimes wanted to get Opus 4.7's take on a change before I kept going. Cross-modal synthesis is something I...
Tesla FSD Saved Me in Just 100 Miles
I used tesla model FSD for 100 miles only and it already saved my skin once already. Its worth everyone switching to FSD.
Electric Ferry Cuts Energy Use 88% With Zero Emissions
Battery-electric ferry reduced energy use 88% versus a diesel ferry during 16 months of operation in Norway, carrying 41,000 passengers per day back and forth over a river. Plus, 0 tailpipe or grid emissions from the BE ferry since Norway's...
New OSS Tool Discovered for E2E Testing Despite Google Lag
Early warning signal for the Google execs who might follow me: Your index doesn't refresh fast enough for github repos, and so I had to use my OpenClaw and Exa to find this new and very powerful OSS for E2E...
Standardize Pipelines to Achieve SaaS‑Speed Enterprise Platforms
RT Want SaaS-level speed in the enterprise? Standardize pipelines, reduce configurations, and productize your internal platforms. #DevOps #PlatformEngineering @Star_CIO https://t.co/e4TERhpY2r
Key SEO Takeaways From Google's Liz Reid Interview
I listened to the latest interview of Google's Liz Reid so you don't have to. Here's everything useful for SEO that I learned over an hour: . . . Thank you. Follow for more updates like these
Exploding Model Capabilities Chart Is Key Benchmark
NEW EPISODE: Understanding the most viral chart in AI @tracyalloway and I talk to @ChrisPainterYup and @joel_bkr of @METR_Evals about what this chart of exploding model capabilities is actually showing, and why they think it's the key benchmark to watch https://t.co/11P3UKZkE8 https://t.co/Dt3HYNOWyu
Community Solar Saves $6.5 B, Avoids CA Gridlocks
Community-scale solar offers $6.5 billion in savings, bypassing California gridlocks #energysky -- via pv magazine global: https://t.co/f4WARfFyOx https://t.co/asqUO1Ty4B
Renewables Dominate Future Grids; Nuclear's Role Marginal
New paper: "Perspectives on nuclear power" Systems with renewable energy, storage, and demand response dominate least-cost future energy system options under realistic conditions. New nuclear contributes only marginally. Past studies of nuclear exaggerated its role by using unrealistically low overnight capital...
Enable WhatsApp Two‑Step Verification: Simple, Better Than Nothing
Whether you just joined @WhatsApp or have been using it for years, it's a smart idea to enable two-step verification. Here's how, step by step, and why it's not as good as 2-factor authentication, but better than nothing... https://t.co/KDT8J6yjkd #whatsapp...
AI Twins Boost HR Efficiency, Threaten Talent Acquisition Jobs
The AI Twin Is Learning Your Job SHRM's 2026 AI in HR full report finds 89% of AI-adopting organizations report operational efficiency gains, and 27% have deployed AI deepest in talent acquisition: the function AI can replace most cleanly. The productivity...
Access Real-Time Health Data via Flexpa API
we’re building @flexpa so this is possible for health data. with flexpa your current, up to date clinical and claims data (insurance) is all available by API. free for patients. try it yourself: https://t.co/X1yvkf1vpS and/or download our AI-powered app: https://t.co/HBzTO6BwPz
Free Shipping This Weekend for Indie Bookstore Day
There's free shipping at Bookshop.org this weekend to celebrate Indie Bookstore Day, if you're looking for a new read https://bookshop.org/p/books/metallic-realms-a-novel-lincoln-michel/0a3abce8348fccc4?ean=9781668058671&next=t
Relevant Ads Benefit Advertisers, Users, and Meta Alike
Advertiser, users, and Meta alllll win when the most relevant ads are served to the most relevant users.
Unified Hiring Ecosystem Boosts ROI in AI Era
#Webinar From Career Site to a Unified Hiring Ecosystem: Driving Meaningful Outcomes and ROI in the Age of AI Discovery @HR_Exec https://t.co/d4IWQ8jDe1 #HCM #HRM #HumanResources #HRTech #CHRO #FutureofHR
Facial Age Acceleration Predicts Earlier Death, Varies by Job
Face photo-based age acceleration predicts all-cause mortality and differs among occupations "We found that face photo-based age predicts all-cause mortality for middle-aged and older individuals meaning that those age faster based on their face photo die sooner." https://t.co/QUUzK4fe9G
AI Success Depends on Process, Not Magic
AI isn’t magic. It’s a process. 8 steps: 👉define problem 👉collect/prepare data 👉choose model 👉train 👉evaluate 👉fine-tune 👉deploy 👉ensure ethics & safety Real value comes from running this loop well. #AI #MachineLearning #DataScience #ResponsibleAI https://t.co/9dCrDBVWrW
CTO Prays to Dario Before CEO's First AI Demo
CTO praying to Dario before CEO gives first live demo of the AI agent to an enterprise customer
Beware: Fake Login Alerts with Password Reset Links
Received an email from X warning you of new or unusual login attempts, with a handy 'change password' link? Beware, it's a slick new phishing attack that can trick even the most vigilant user. I've seen this with other sites...
Regulation Shifts From Entities to Protocols: Law Becomes Code
Financial regulation in a zero-human world isn't about controlling entities It's about governing protocols The shift from noun to verb From who to how Code is law becomes law is code We're not ready for this
Easy Vouch Boosts PR Quality Without Slowing Flow
A couple months in and Vouch in Ghostty is working extremely well. Our PR quality is up and the rate of PRs has not gone down at all. Getting a vouch is easy, and the minimal barrier to entry easily...
AI Reliability Engineer: The Future Code Orchestrator
There is a new role is that is needed in the world of AI: The AI Reliability Engineer. The developer of the future will be an orchestrator of agents, a master at understanding code management, a new breed that can...
Virtual Assistants Enable Deeper Financial Engagement, Not Just Automation
The opportunity is not just automation. It’s deeper engagement. Virtual assistants can help customers manage money, not just answer questions. https://t.co/dcRagBD5q7
Accidental $1k Ad Spend: E‑commerce Founder Rite
You're not an 'ecom founder' until you've accidentally spent $1,000 on an ad set you forgot to turn off. It's a rite of passage.
AGI's Toughest Challenge: Matching Socks, Not Math
The first self-aware robots are coming for your laundry. Turns out the hard part of AGI was never the math. It was matching socks.
Hybrid Hydrogen Costs Drop to €2.5/kg at Mediterranean Ports
The Hydrogen Stream: Levelized cost of hydrogen at Mediterranean ports can be as low as €2.5/kg for hybrid systems #energysky -- via pv magazine global: https://t.co/ZkkLBonwRb
AI Chat Models Are Just Prompts, Not Builders
ChatGPT is just a less useful version of Codex that can't build and ship stuff. Same for regular Claude vs. Claude Code. It's all just prompting the AI at the end of the day.
Humanoid Robot Shatters Half-Marathon World Record
A Humanoid Robot Beat the Human World Record for a Half Marathon by @EddyTheGent https://t.co/Tf5m3MY4og https://t.co/tvdwI3BG5q
Progress MS-34 Launch Tonight at 6:21 Pm EDT
Progress MS-34/P95 getting ready to launch this evening at 6:21 pm EDT. NASA coverage begins 6:00 pm EDT.
Speed Is Relative: Drone Moves 100 Km/H in Air
From a physics point of view, is the drone actually moving at 100 km/h, or is it effectively stationary? Answer is pinned in comment section. 👇
Clean Energy Buffers EU Electricity Costs During Gas Spikes
The more clean energy a country has, the less it pays when gas prices spike. The chart shows electricity price sensitivity per €1/MWh rise in gas across EU countries in 2025. @CREACleanAir https://t.co/izKNUNPQwJ https://t.co/l6HAQKC1fi
Enterprises Question Trust in Anthropic After Recent Issues
I attended Google Cloud Next this week and @AnthropicAI had a giant spread there. Booths, of course, but also rented out a swanky restaurant. After what they’ve pulled recently with performance, price and quality half-truths, I was thinking about enterprise...
Cost Caps Not Spending? There's Likely a Reason
A lot of brands and agencies make this mistake. If cost caps aren’t spending - it’s probably for a good reason.
Human and AI Intelligence Occupy Orthogonal Planes, Not a Line
🚨Intelligence isn’t a line. It’s a plane. Human cognition and AI computation don’t share the same axis--they run on orthogonal vectors. 👉 This is the heart of anti-intelligence. AI delivers scale, speed, pattern fluency and statistical reach… but has no embodiment,...
AI-Driven Software Will Push Shorter Vendor Contracts
Contract terms will shorten in the future. If AI commoditizes much of software and switching costs come down (which they are)… then I am more much likely to go with the vendor that offers shorter contracts I’ll still do *some* longer-term, but not...
Keep Experience Adaptive, Not Fixed, Thanks to AI
This gets at something I see all the time. Experience only stays valuable when it keeps updating. AI lowers the cost of trying, learning, and changing your mind. That makes stale judgment easier to spot. The most effective operators treat experience like a...
Unified AI Healthcare Regulation Accelerates Patient Access
"50 competing standards cannot be the answer for a technology this consequential... many assume that regulation slows down transformative technology, but history suggests otherwise." Great piece by @HashemZikry calling for consistent regulatory guidance to **improve**, not impede, the solving of...
Phishing Lockout Resolved Quickly Thanks to Community Support
Two days after falling prey to a phishing attack and getting locked out of my account, I'm back in. Sincere thanks to @X for resolving this so quickly. So grateful also to @lisaabramowicz1, @Brad_Setser, @AnnaEconomist, @baselinescene, @GagnonMacro and many others...
Your Router Silently Tracks You—18 Ways to Stop It
Your Wi-Fi router isn't "accidentally" tracking you. It's a feature, not a bug. I searched for a specific medical symptom once. 10 minutes later, my partner had an ad for it on their laptop. It’s called "IP-Bridging," and it’s happening through...
AI Skills Tests Replace Misleading Resumes in Hiring
The Resume Had a Good Run HR leaders are retiring the traditional CV as the first impression in hiring, replacing it with AI-driven skills assessments that test actual capabilities. SHRM's 2026 HR trends data shows 70% of candidates admit to misrepresenting...
AI Imagines Stata Center's Futuristic 2500 Design
What does AI think the Stata Center will look like in the year 2500? ChatGPT, Meta AI, & Grok chimed in. https://t.co/dhIJxYKs2w