Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves first CIRM‑funded gene‑editing therapy for rare immune disorder
The FDA has granted approval to KRESLADI, a gene‑editing therapy from Rocket Pharmaceuticals that treats severe leukocyte adhesion deficiency‑I in children without a matching bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine (CIRM), highlighting the agency’s impact on translational research.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
RevolutionEHR introduced RevPay, an embedded payments solution that integrates checkout, patient records, and reporting within its AI‑native platform. The tool supports card, ACH, digital wallets and offers optional patient surcharging, promising to reduce processing fees that can cost $10,000‑$18,000 annually for a $1 million practice. By providing real‑time transaction dashboards and automatic ledger mapping, RevPay aims to streamline revenue collection and free staff for patient care. The launch positions RevolutionEHR as a comprehensive financial and clinical workflow hub for optometry practices.
American Healthcare REIT (AHR) posted a strong Q4 2025, turning a $32.4 million loss into a $10.9 million profit, driven by its Trilogy senior‑care campuses. Trilogy’s same‑store NOI rose 18.4% year‑over‑year and occupancy hit 90.6% in the quarter, while Medicare Advantage rates...
The FDA has classified Boston Scientific’s recall of certain Axios Stent and Electrocautery‑Enhanced Delivery Systems as a Class I recall, the agency’s most serious designation. The recall follows multiple reports of deployment and expansion failures during stent placement, resulting in...
University of Utah Health researchers are leveraging AI and machine learning to "reimagine" electronic health records (EHR) through the federally funded Reimagine EHR initiative. Backed by roughly $35 million in federal grants and corporate partnerships, the program has produced eight AI‑driven...
Abbott received FDA approval for its next‑generation CardioMEMS HERO reader, a pulmonary artery pressure device for heart‑failure patients. The HERO unit is 60% lighter than earlier readers and incorporates built‑in Wi‑Fi and cellular connectivity, allowing measurements anywhere. The upgrade builds on...
University of Mississippi Medical Center announced that its outpatient clinics will resume normal operations statewide on March 2, following a cyberattack that shut down its IT systems on Feb. 21. The center has regained access to patient records and will...
Minnesota’s Department of Health reports that hospitals and clinics in the state earned at least $1.34 billion in 2024 from the 340B drug discount program. Participants received $3.045 billion in discounted medicines but paid $1.53 billion plus $165 million in administration fees. The largest...
Ultrasonic spray coating is emerging as a core engineering discipline for drug‑eluting implants, with parameters such as drug‑to‑polymer ratio, nitrogen carrier‑gas flow, nozzle height, and spray power dictating coating thickness, profile, and elution behavior. The article explains how variations in...
Researchers at Cornell’s Weill Institute introduced QUASARR‑seq, a high‑throughput assay that measures promoter and enhancer activity simultaneously. The study found that most human regulatory elements can function as both promoters and enhancers, following a unified regulatory logic. A bidirectional feedback...
Kenco’s vice‑president of life sciences, Tim McClatchy, detailed how the firm is hardening cybersecurity across its manufacturer‑to‑home delivery network while deploying AI to streamline labor planning and route optimization. He explained the specific encryption and verification steps used at each...
Morpheus is an AI‑driven platform that ingests alerts from a hospital’s existing security stack—SIEM, EDR, firewalls, NDR, email security, DLP and identity tools—and stitches them into a single ransomware kill‑chain view. By correlating these signals, it can surface an attack...
President Trump’s "most‑favored nation" (MFN) drug pricing agreements, touted as a safeguard against excessive prescription costs, have been revealed to run for three years for several participants. SEC filings show that 16 pharmaceutical firms have entered these deals, each with...
The Centers for Medicare & Medicaid Services (CMS) is evaluating artificial‑intelligence tools to improve the precision of Medicare Advantage coding and hospital billing. The initiative is part of the Trump administration’s proposed CRUSH (Combatting and Reducing Unnecessary Spending and Healthcare...
The recent episode of HBO’s drama "The Pitt" portrayed a hospital’s IT systems being shut down by ransomware, forcing clinicians to revert to paper‑based processes. Hours later, the University of Mississippi Medical Center confirmed a real ransomware breach that crippled...
Median Technologies announced it will present at TD Cowen’s 46th Annual Health Care Conference in Boston from March 2‑4, 2026. CEO Fredrik Brag will discuss the company’s latest AI‑driven SaMD developments and upcoming milestones on March 4 at 11:10 am ET. The presentation will be...
The federal government unveiled a $50 billion Rural Health Transformation Program, allocating $10 billion per year to states for preventive care, workforce development, and technology upgrades. HHS also announced stricter enforcement of information‑blocking rules, creating a portal for patient‑data complaints. Simultaneously, officials...
The American Hospital Association (AHA) submitted formal recommendations to the Assistant Secretary for Technology Policy and the Office of the National Coordinator (ASTP/ONC) regarding the Health Data, Technology and Interoperability (HTI‑5) proposed rule. The rule seeks to deregulate certification criteria,...
The American Hospital Association (AHA) unveiled the agenda for its first‑ever Healthier Together Conference, set for May 12‑14 in Dallas. The three‑day event will host more than 40 sessions delivered by nearly 200 speakers representing over 100 organizations from 20 states....
Researchers have engineered size‑shifting lipid nanoparticles that grow from ~100 nm to >300 nm after intraperitoneal injection, exploiting a capsule‑filter mechanism that blocks entry into the liver and spleen while allowing passage to the pancreas. The enlarged particles deliver mRNA payloads—including CRISPR‑Cas9...
Survival rates for congenital heart disease (CHD) have risen, creating an estimated 1.4 million adult patients who often require repeat surgeries. At the 2026 Society of Thoracic Surgeons meeting, Mayo Clinic researchers presented a machine‑learning model that isolates 15 key variables...
The FDA approved Hernexeos through the national priority voucher program, a mechanism that fast‑tracks drugs addressing unmet medical needs. Industry leaders are evaluating direct‑to‑consumer (DTC) models to broaden access to HIV prevention tools, leveraging digital and telehealth channels. Additionally, the...
Three bispecific antibodies targeting PD‑1 and CTLA‑4—lorigerlimab, volrustomig, and cadonilimab—illustrate divergent engineering strategies. Lorig erlimab relies on a knob‑into‑hole heterodimer, volrustomig adopts a common light chain format, and cadonilimab incorporates Fc‑silencing mutations. Their distinct designs have produced markedly different safety...
AI‑driven imaging firm AIRS Medical will showcase its SwiftMR™ MRI reconstruction platform at the 2026 European Congress of Radiology in Vienna. Attendees can bring anonymized DICOM data to Booth #AI-19 for real‑time reconstruction, demonstrating faster scans and sharper images. The...
CFG Health launched CareLink, a proprietary 24/7 telehealth platform designed for correctional facilities. Built on existing security‑issued tablets, the solution delivers emergency triage, primary, behavioral, and specialty care while maintaining HIPAA compliance. The platform combines CFG’s in‑house clinicians with external...
Acupath Laboratories has partnered with Azer Scientific to install the first AzerView LH510 digital pathology scanner in the United States. The LH510 offers high‑resolution whole‑slide imaging and streamlined workflow features designed for clinical, academic, and reference labs. The installation marks...
Bayer's HYRNUO (sevabertinib) received accelerated FDA approval on November 19, 2025 for adult patients with HER2‑mutated, non‑squamous non‑small cell lung cancer who have progressed after prior therapy. The approval is based on the single‑arm SOHO‑01 trial, which enrolled 122 patients across 78...
ResMed has evolved from a cyclical device maker into a digital‑health platform anchored by sleep‑apnea therapy, cloud‑connected monitoring and recurring software services. The company posted Q2 FY2026 revenue of $1.4 billion, up 11% YoY, while gross margin climbed to 61.8% and...
PeerSupport.io, a Yukon health‑tech startup, launched CoWork, an autonomous AI browser that executes EMR and web‑based tasks through voice commands. In pilot clinics the tool can send referrals, renew prescriptions, and pull charts in under 11 seconds, delivering roughly 10.5...
GT Medical Technologies released Phase IV registry data showing that GammaTile brachytherapy, implanted at the time of surgical resection, achieved 92.3% local tumor control in newly diagnosed brain metastases after a median 12.4‑month follow‑up. The study of 51 patients reported a...
VahatiCor’s A‑Flux Reducer System, a self‑expanding, recapturable coronary sinus device, was implanted in a first‑in‑human cohort of 12 patients with coronary microvascular dysfunction or obstructive CAD. Eleven procedures were completed without any device‑related complications, and patients experienced significant improvements in...
In February 2024 CMS unveiled “shadow bundles,” a modified BPCI‑A methodology that collects episode cost and quality data for hospitals and specialists without their explicit participation. The information is shared primarily with ACOs, MSSP participants, Medicare Advantage plans, and large...
UNC Health has launched the world’s first standardized rare‑disease coding tool by embedding the Mondo Disease Ontology into Epic’s EHR through the February 2026 IMO Core update. The integration adds nearly 5,000 new rare‑disease codes and revises more than 25,000...
The FDA released a draft guidance titled “Certification Process for Designated Medical Gases,” outlining how manufacturers must obtain certification and meet annual reporting requirements. The document defines qualifying products, required submission content, and FDA’s evaluation criteria. It replaces the 2015...
The Inflation Reduction Act reshapes Medicare Part D by granting CMS authority to negotiate prices for high‑cost drugs and instituting a $2,100 annual out‑of‑pocket cap for beneficiaries starting this year. The first ten drugs, including Ozempic and Wegovy, will have negotiated...
Recent research highlights that BMI alone misclassifies up to 34% of adults, masking critical changes in muscle mass and fluid balance. Rapid weight loss driven by GLP‑1 therapies can cause substantial muscle and intracellular water loss while extracellular fluid rises,...
Evernorth, Cigna’s health‑services arm, has confirmed it now fully owns CarepathRx after completing the acquisition last year. CarepathRx provides home and ambulatory infusion solutions to roughly 10% of U.S. hospitals, strengthening Evernorth’s specialty pharmacy footprint. The deal builds on a...
I used to teach that "aging is just wear-and-tear." A new Nature paper used 7 days of wrist-wearable data from ~62,000 adults and found your circadian rhythm patterns (amplitude + stability) and MVPA predict inflammation-linked biological aging. Low rhythm amplitude and poor...
A leader of this next wave of AI-focused biotechs has completed its IPO, a milestone tarnished by a brutal first few hours of trading. Day 1 for $GENB: -23% https://t.co/u3WQcDD3jL
The article explains how repeated failed quit attempts create learned helplessness among smokers, undermining their belief that effort matters. It contrasts this with self‑efficacy, a task‑specific confidence that predicts successful cessation. Pharmacotherapy combined with structured counseling can double quit rates,...
"Smart” doesn’t mean distant. The smartest hospital ecosystems actually bring clinicians closer to patients by reducing administrative burden. Insights from Jeff Fallon at eVideon: https://t.co/x7o1COnGIe @eVideon @TigerConnect #SmartHospitals #HITsm https://t.co/PVVG70mbKN
An intriguing tale of three cities. How do the PD1xCTLA4 bispecific agents lorigerlimab, volrustomig, and cadonilimab stack up when it comes to design and performance? Some useful and pointed lessons here for biotech execs: https://t.co/xaSW15Fvdl https://t.co/dhXbiI3N6v
The United States recorded 2,280 measles cases in 2025, the highest tally since 1991, and early 2026 has already seen 910 additional cases, concentrated in South Carolina, Utah and Florida. Low MMR vaccination coverage—just 64% for a single dose—has been...
Atrium spins out of Avidity, aiming to target rare heart diseases with RNA https://t.co/xLp2oQDHGy $RNA $NVS #startups
“The era of de novo proteins is coming a lot faster than probably people recognize,” Generate's CEO Mike Nally tells me. “I think within the next year or two you’ll start seeing de novo designs enter the clinic.” https://t.co/u3WQcDD3jL
ShopRite, part of Wakefern Food Corp., has introduced a limited‑time "Wellness Your Way" starter kit for customers beginning GLP‑1 therapy. The kit bundles medication samples, coupons and a dietitian‑crafted wellness guide, explicitly tying the chain’s pharmacy and grocery divisions. The...
Hospitals aren’t asking IF they need virtual care anymore — they’re asking how deeply it integrates. Insightful take from @_artisight's Jay Lyonett at #ViVE2026. 👉 https://t.co/ckEzNYH8oS
An important study just came out that is the first to evaluate patient safety when it comes to ChatGPT Health. Millions of people are using LLMs every week to triage health conditions, but this new study has found concerning inconsistencies. https://t.co/etjthA2olM
AI is helping to make the diagnosis of rare diseases. A new multicenter study in Japan showed smartphone AI diagnosis of acromegaly via hands was better than experienced endocrinologists https://t.co/qBiazetToV https://t.co/dSZpJ2us84
Former surgeon general: The Senate must not approve an SG who can’t practice medicine https://t.co/TfgRw59xFd
Here's the link to watch yesterday's webinar on venture capital, a companion to this year's top 100 biotech VCs list with @ChrisDoko Lots of positive feedback here. Post your thoughts. https://t.co/c16y04mFsD
