Marías' “No One Noticed” Hits 1 Billion Streams
The Marías' "No One Noticed" has surpassed 1 billion streams on Spotify, two years after the song slowly went viral on TikTok and got a boost from Billie Eilish singing along on Instagram. https://t.co/LfxZAlMrjN
Soyuz‑5 Launch Delayed to March 29, Flight Early April
The rollout of the first Soyuz-5 rocket to launch pad Site 45 in Baikonur, Kazakhstan, was postponed from today to March 29, in turn, pushing its inaugural flight to April 2, at the earliest, according to Kazakh media. Context: https://t.co/DBcHRiQe36 https://t.co/S8p6AAE3IL
Allogene's Interim Data Hints at Off‑Shelf CAR‑T Breakthrough
This week's Biotech Scorecard: Allogene $ALLO: A preview of its April interim analysis. Very interesting (to me, at least) There just might be a path forward for off-the-shelf CAR-T therapy in B-cell lymphoma. Frontline consolidation. Read all about it: https://t.co/tcPFelUH3C
Gene Therapy Turns Aging Into Editable Code
Gene therapy isn't just targeting diseases anymore—it's targeting aging itself. The hallmarks of aging are becoming editable code. Longevity Escape Velocity isn't a fantasy. It's an engineering problem. And we're solving it.
Gyms Transform Into Future Longevity Centers
Gyms are evolving to integrate services that are looking beyond near-future fitness and into longer-term benefits. The concept of longevity has gained traction in recent years, and gyms are tapping into this trend. In this article, by analysing real-life trends and examples,...
Harvard's Light Chip Enables Sorting Mirror-Image Molecules
Harvard’s twistable light chip could give drug developers a new tool for sorting mirror-image molecules https://t.co/WkjjD38exo https://t.co/5kr4d9f6sa
AI Scientist Writes, Experiments, Publishes Papers Autonomously
As a medical school professor, I've spent decades writing papers and reviewing studies. Now AI can do it all -- start to finish. Researchers from Sakana AI, Oxford, and UBC just published in Nature: "The AI Scientist" -- a system that...
Eggs as Cheap, Scalable Factories for New Medicines
I have a story today about the quest to turn eggs into low-cost factories for medicines. Gift link: https://nyti.ms/4bzSabB
True Mastery Lies in Mental Adaptability, Not Technique
The hardest skills have nothing to do with technique. Adaptive. Clear in thinking. Emotionally fit. Present. You cannot muscle your way into any of them.
Code Ran Fine, but Biology Flagged Label Error
I almost sent a figure with wrong cluster labels to my collaborators. The R code ran perfectly. No errors, no warnings. I caught it because cluster 2 showed upregulated genes in RNAseq but reduced chromatin accessibility in ATACseq. Biologically, that's backwards....
Unplanned Nomad Life Cripples Productivity Across Time Zones
I'm a digital nomad right now... and I really hate it. I've spent the last 6 weeks in Bangkok + Germany, working on 12 hour time differences from New York, and I find it damn near impossible to accomplish my professional...
Awe Shrinks Problems, Boosts Perspective
There's this thing that happens when you stand in front of something so big your brain can't quite process it. Dacher Keltner at UC Berkeley calls it awe, and his research suggests it does something interesting to us. It makes our...
AI's Influence on Human Thought Tops Amazon Rankings
🤔Something very interesting is happening. My book on AI and human cognition is now showing up on Amazon’s top lists in: 🔴Epistemology 🔴Cognitive Psychology 🔴Medical Cognitive Psychology Interestingly, this distribution wasn’t planned. The larger conversation is now shifting, and not about what AI can do, but...
New Big Ticket Episode Features Star‑studded Trailer for April Release
Zendaya. Robert Pattinson. Alana Haim. Mamoudou Athie. It’s a new episode of @Fandango’s Big Ticket, live now. Here’s a clip. In theaters April 3. https://t.co/Kvhfntn06u
Match Athlete Speed to Zones, Ditch Mileage Metrics
If you know your athletes, and you know how fast they should be going in each zone, they are one and the same.
Finding Joy in Silly Morning Moments Together
Drove my daughter to school this morning mostly in silence until we saw a lady speed walking, just flailing her arms around, looking a bit silly. We both looked at each other and chucked. Me: Nice technique. 14: You go, Queen. Love our...
Exercise Beats Optional: Key for Prostate Cancer Survival
As a medical school professor, I can tell you: the textbooks got this one wrong. We taught that once you have prostate cancer, exercise is nice but optional. New data says it may be the most powerful tool in your arsenal. 828...
When Love Becomes a Sacred, Unheld Whisper
Thursday Poem: Have you ever loved someone so deeply you almost whisper their name to God then stop because you are not sure if you are asking for them or asking to be released Has it been love if it lives more in your spirit...
We Plan Weekends, Not Our Futures—Change Needed
I'm absolutely blown away by the amount of people who spend more time planning their weekend than planning their next decade. Two hours choosing a restaurant Zero minutes designing their life And wonder why nothing changes...
Break the Fitness Fad Cycle for Lasting Sustainability
Fitness is a carousel of recycling fads, the key is exiting the cycling and finding something meaningfully sustainable.
Nutrients, Not Empty Calories, Drive Athletic Performance
I see a lot of athletes chasing calories because they were told '"just eat more", but not prioritizing nutrient dense foods. Calories provide energy but nutrients determine how well you perform, recover, and adapt. If you want strength, speed, and endurance, you...
Success Now Depends on Capability, Not Job Title
Hot take: I think we are moving from a world defined by roles to a world defined by capability. The old labels still exist, but they are getting less useful. Marketer. Developer. Designer. Strategist. What matters more is whether you can think clearly,...
Art Basel HK Draws Crowds, Yet Auction Sales Plunge
Latest report on Art Basel Hong Kong and Hong Kong's art market from Cathy Fan and I of The Asia Pivot team @artnet. Sales were made but big turnout on VIP day 1 did not immediately translate to big business....
Lifespan Extension Doesn't Guarantee Morbidity Compression, Study Shows
“These findings challenge the assumption that lifespan extension necessarily compresses morbidity, highlighting the need to consider lifespan, healthspan, and CoM as endpoints when evaluating anti-aging interventions. We do not claim that life-extending interventions categorically fail to achieve CoM; rather, we demonstrate...
Ignoring Climate Risks Threatens 20% Global GDP Loss
The sad truth... This pattern is not limited to climate change. Too often, the economy stands above health, peace, environment and even people. Nothing seems to come before the economy... When it comes to climate, the economy is often treated as the...
Good Research Drives Long‑term Success, Not Immediate Timing
Nick Sleep on focusing on what you can control "The quality of our research-based decisions overwhelmingly determines whether we will do well in the long run. But it has almost no influence over the timing of these results."
WBD Shareholders Vote April 23 on $110B Paramount Merger
That’s it! After being unanimously approved by both $WBD & $PSKY board of directors, WBD has now the date set for their shareholders to vote for or against #DavidEllison’s #Paramount deal to acquire WB: the special shareholders meeting is scheduled for...
UK Economy Vulnerable to Commodity Shocks, Politicians Ignored
Having read @EdConwaySky book on the Material World a few years ago it made me realise how vulnerable the UK economy would be to a commodity shock, and how we've been failed by our political class over the years. I'm...
Menstrual Phase Influences GI Discomfort During Exercise
How does the menstrual cycle affect gastrointestinal symptoms during exercise? 🩸 This new study recruited 12 eumenorrheic females to complete 2 x 45-min bouts of a simulated football match on a treadmill ⚽️ Simulations were completed in… 1️⃣ Phase 1 (P1, days...
Measure Success by Your Goals, Not Others' Returns
Your progress matters more than anyone else’s returns. Goals, not comparisons, define success. #FinancialPlanning #LongTermInvesting https://t.co/JQzKXSfrXO
Fuel Your Performance: Smoothies Solve Athlete Underfeeding
No appetite? You’re not alone. One of the biggest mistakes I see with athletes is underfueling simply because they’re not hungry especially during intense training seasons. 👉 That’s where smoothies come in. Protein fruit smoothies are one of the BEST ways to: ✔️...
Penelope Trappes Assembles Star Artists for Requiem Reworked
Penelope Trappes recruits Julia Holter, Midwife, Gazelle Twin, and more for 'OPVS NOVUM: A Requiem Reworked' https://t.co/QPkcTeXZb7
Discipline vs Ego: Know When to Let Go
There's a fine line between conviction and denial. Holding on when the thesis is intact? That's discipline. Holding on because admitting you're wrong hurts? That's ego. The facts don't care which one it is. Your portfolio doesn't either.
Midlife Metabolism Shifts Demand New Weight‑Loss Strategies
A lot of midlife women are not failing weight loss advice. They are following advice that may be physiologically mismatched to this stage of life. In this episode of The Podcast by KevinMD, Marsha Shepherd Whitt challenges a message clinicians and patients...
Guard Your Personal Effectiveness Against Endless Work Distractions
“Our modern-day working culture & personal habits have created the infinite workday. The non-stop emails, meetings, phone calls, notifications, group chats, messages, etc., are assaulting ur #personaleffectiveness. You must protect it.” > https://t.co/p5jUUCnzIs #careeradvice https://t.co/jj29JyVLiU
Trading Results Mirror Habits, Not Intelligence
Your P&L is feedback from your trading habits, not your intelligence. Profitable trading is psychology and behavior management. Fix your bad habits and you fix your unprofitable results.
Books to Break Free From Middle-Class Limiting Beliefs
10 Books That Help You Escape The Middle-Class Mindset That Most People Stay Stuck In https://t.co/QhsDLahvwu
Memory Shapes Identity; Forgiveness Prevents Loneliness
Two thoughts from Stephen Elliott "What we remember, and how we order and interpret what we believe to be true, are what shapes who we are." "If you never forgive you'll always be alone."
Fitness Industry Misreads Post‑Workout CNS Fatigue
The fitness industry misunderstands post-workout CNS fatigue more than any other physiological concept. Learn how it actually works in this week's free Patreon article. https://t.co/L5B5n6Ltt0
Mini Brains Rewire to Balance Digital Pole
🔺 These Mini Brains Just Learned to Solve a Classic Engineering Problem 🧠 In a step toward biological computing, brain organoids rewired their networks as they learned to balance a digital pole on a cart. https://t.co/w2wHDTvIVp https://t.co/h51xTVlR4D
Roksanda Concept Store Merges Fashion, Art, Architecture
Stepping inside the new roksandailincic Concept Store reveals a space operating as manifesto. Roksanda has always held dialogue between art and architectural design alongside her clothes, but the true resonance is in the curation: rare furniture by betonbrutlondon, glass sculptures...
Michael Jackson Biopic Pre‑Sales Launch US‑First via Lionsgate
MICHAEEEEELLL, THEY DONT REALLY CARE ABOUT USSSSS True news, general ticket Pre-sales for KING OF POP #MichaelJackson’s music biopic #MICHAEL are officially online. But only through #Lionsgate at US #BoxOffice, since #Universal hasn’t kicked off Pre-sales overseas yet, as they are...
2026 Box Office Bet: Sequels Drive Billion‑Dollar Hits
"The big horse closes out the presentations. The question for 2026 is whether the return to the very familiar - 5 sequels - will do as amazingly as the line-up went in 2025. Moana, but live. Grogu, but on the big...
Help Kids Trust Their Own Growth Timeline
When children compare themselves, they’re really asking, “Am I doing okay?” Not all growth is visible. Some happens quietly, before it ever shows. As parents, our job isn’t to speed them up it’s to help them trust their own time. Comment “GUIDE” and I’ll share what to...
Malaysia: Multilingual, Affordable Hub for Southeast Asia
Conversation with friends and why I m so bullish bout Malaysia as the gateway to Southeast Asia, both business & tourism; 1. Multi language. We speak Malay, English, Chinese and Tamil 2. Affordable and accessible. Central in this region, price of living...
Data Powers AI: Focus on Foundations, Not Flash
Everyone wants to work in AI… until data is mentioned. That contrast says a lot about where we are today. I recently came across an experiment with 100+ postgraduate students. When asked who wanted to work in AI, every hand went up. When asked...
First Soft 3D Hydrogel Semiconductor Replicates Living Tissue
World’s First Soft #3D Hydrogel Semiconductor That Mimics Living Tissue by @tweetciiiim #EmergingTech #Innovation #Technology https://t.co/jt0fxgrrdt
Jake & Heeseung's K‑Pop Collab Nominated for iHeartRadio
Wait... Jake and Heeseung's collaboration with Flo Rida and Paul Russell is up for Favorite K-Pop Collab at the iHeartRadio Music Awards tonight... what happens if they win...
Adult Realization: Whimsy Becomes Serious When Names Change
my first glimpse of the ick of adulthood was when they renamed 'Gleaming the Cube' to 'A Brother's Justice'
Founder Mode: Conquer Fear, Execute Relentlessly
Founder Mode is an arrival. It means you’ve overcome the fear of failure, and you simply execute to overcome any obstacle in your way.