NMN Eases Liver ER Stress, Resets Circadian Rhythm
Nicotinamide mononucleotide attenuates hepatic endoplasmic reticulum stress and modulates circadian rhythms in young mice with diet-induced obesity https://t.co/mXbwdQlAzt https://t.co/iQxPG0NKYf
Centrum Silver’s Anti‑aging Claim Rests on Limited Evidence
Have ya’all heard the breathless news that daily multivitamin use slows down biological aging and preserves memory? Celebrity wellness influencers like Dr. Rhonda Patrick claim that the COSMOS study found Centrum Silver improved memory and slashed aging by 4 months...
Three Key Nutrients for Brain Longevity, Plus Polyphenols
As a bioscientist studying aging, my top 3 nutrients for brain longevity are: → Omega-3s (fatty fish 2–3x/week) → Vitamin B12 (beef, dairy) → Choline (2 eggs daily) Plus plenty of polyphenol-rich foods: berries, extra virgin olive oil, cocoa, nuts, and coffee.
Loading Speeds Creatine Saturation; Maintenance Works Too
Creatine loading is back, but there are some things you need to be aware of⬇️⬇️ Bodybuilders have been doing 'creatine loading' for decades: take 20-25 g/day for a week and then switch to a maintenance dose (3-5 g/day) Whereas over the...
Protein and Strength Training Boost Endurance Performance
Dr Mike Ormsbee will discuss why protein intake and strength training may deserve more attention in endurance sport: https://t.co/eJsRhTCgt2 https://t.co/TxUrrObju8
Protein Overload? Prioritize Fiber and Unsaturated Fats
I’ve ended up on the “why is there so much protein in everything?!” side of threads and I’m going to prentend that everyone is asking this question. Here’s the thing: protein is essential, but you’re likely getting closer to the optimal...
Time‑restricted Eating Matches Calorie Restriction for PCOS Weight Loss
Time-restricted eating for body weight management in women with polycystic ovary syndrome: a randomized controlled trial “Our results show that in women with PCOS, TRE induced greater weight loss than the controls and was comparable to that achieved with daily CR” https://t.co/fqogoSQpkd
Resistance Training Cuts Fat and Boosts Grip Strength
Exercise, nutrition, physical agent therapy in older adults with sarcopenic obesity: a systematic review and network meta-analysis RT can reduce BF% while simultaneously improving grip strength, representing an effective management strategy for sarcopenic obesity. https://t.co/p0wR2R5M1E
Choose Triglyceride Omega‑3s for Superior Absorption
Not all omega-3 supplements are created equal. Most fish oil on the market is in ethyl ester form, which is cheaper to produce after purification. But it's not found in nature and is less bioavailable. What you want is triglyceride form omega-3s....
Eat 30 Plant Varieties Weekly for Microbiome Health
As a scientist studying aging, I’m fully behind the “eat 30 different plant foods per week” advice. The research linking microbiome diversity to long-term health is compelling. Fruit, veg, legumes, herbs, nuts, and seeds all count — it’s more achievable than...
Apple Cider Vinegar: Myth or Weight‑Loss Reality?
In recent years, vinegar, and in particular apple cider vinegar, has been hailed and promoted for its weight loss properties. Is there some truth in these claims? Read the blog to find out more: https://t.co/pDA85IH7fx https://t.co/VPQGqKJUw0
Modern Bodies Face a Silent Energy Crisis
Fuel for thought 👉 ”A quiet energy crisis may be unfolding within modern bodies…” and brain 👨🏻⚕️🧠 🔗 https://t.co/19h7kfdhNK 🗣️@HanCritchlow
9+ Ultra‑Processed Servings Daily Spike Heart Risk
As a medical school professor, I want you to count your ultra-processed food servings today. A major new study from the Multi-Ethnic Study of Atherosclerosis (MESA) just presented at ACC.26 followed thousands of Americans for years. The findings are stark: -- 9+ servings...
High-Dose Vitamin C May Slow Aging, Study Finds
New research in Cell Metabolism suggest high-dose vitamin C might slow aging👇 (details in comments)
Protein and Strength Training Boost Endurance Performance
Explore why protein intake and strength training may deserve more attention in endurance sport, particularly in relation to adaptation, resilience, efficiency, and long term performance. LAST CHANCE to register with 40% off: https://t.co/UXBWDt3JIP https://t.co/WpmoCPKIAH
Mediterranean Diet Boosts VO2max in Endurance Athletes
Mediterranean diet enhances endurance training adaptations 🫁 This new study recruited 60 competitive endurance athletes to a 12 week randomised controlled trial where they were assigned to consume either… 🥗 Mediterranean diet 🍽️ Maintain normal diet (control) Endurance adaptations and gut microbiota were...
Protein Isn’t Essential with Carbs During Workouts
Do I need to take protein with my carbohydrate during exercise? We are all aware of drinks and the gels that are commercially available as carbohydrate sources. But should we be thinking of protein as well? Read the blog for...
Biannual Check‑ups: Health, Finances, and Life Alignment
Every 6 months, I strongly recommend: ✅Blood work (hormone and metabolic panel) ✅Dental cleaning (our oral health is connected to our gut and brain) ✅Financials (review investments, budget, planing, and tithing) ✅ Eye exam (especially if you’re on screens a lot or drive frequently) ✅...
DASH and Anti‑inflammatory Diets Lower SCD Risk, Boost Cognition
Dietary Patterns and Indicators of Cognitive Function “healthy diets, exemplified by the DASH diet for blood pressure control and diets with lower hyperinsulinemia and inflammation potentials, were associated with a lower SCD risk and better cognitive function” https://t.co/Km7DxqqtJa
Creatine Boosts Power Output, Not Cognition, in Active Adults
Creatine is still primarily a physical performance supplement 💊 This new study recruited 40 active participants to complete physical (Wingate) and cognitive testing after either… 1️⃣ Creatine (20 g/day for 7-days) 2️⃣ Placebo (7-days) Cognitive testing was performance before and after the Wingate...
CGM Can't Accurately Predict Endurance Fuel Needs
Continuous glucose monitoring (CGM) is increasingly used in sport, but can it tell athletes how much fuel is left in the tank? This blog explores whether CGM can provide meaningful guidance on fuelling strategies for endurance performance. Click here: https://t.co/j4V3cTKttl...
MIND Diet Slows Brain Atrophy Over Ten Years
Adherence to the MIND diet and longitudinal brain structural changes over a decade: evidence from the Framingham heart study offspring cohort “In this prospective cohort study, greater adherence to the MIND diet was associated with slower brain structural atrophy, particularly...
Bedtime Protein Boosts Recovery without Adding Fat
Eating protein before bed does not automatically lead to fat gain. This blog explains how it can support recovery and muscle health. Read the blog: https://t.co/z3MoMcBdza
Science Shows Seed Oils Aren’t the Health Villains Claimed
How Seed Oils Became Controversial—And What the Science Really Says A food scientist debunks the vilification of seed oils on social media and explains what research says about them. https://t.co/3vkvSpmBod | @sciam https://t.co/MuRLtmBi7U
Whey Protein Boosts Weight Loss in Obesity, Review Finds
Effectiveness of Whey Protein Supplementation in Weight Loss Interventions for Patients with Obesity: A Systematic Review https://t.co/aWeSqmYfFL
Sinclair's 1g NMN: Myth Vs. Cellular Reality
David Sinclair is one of the smartest longevity researchers on the planet. I interviewed him here: https://t.co/dZCOAD5PLU and recently @tombilyeu released an interview with him here: https://t.co/F2pHBy9xuw... ...in which @davidsinclair says he takes 1g of NMN every morning. But some people say...
Supplements Offer Small Endurance Gains, Unclear Adaptation Benefits
Supplements like sodium bicarbonate, beta-alanine, beetroot juice, and caffeine can boost endurance by ~1-3%. What about their impact on adaptation? Read the blog: https://t.co/nOvClAp15h https://t.co/R0OaDs8m92
Keto Diet Induces Ulcerative Colitis Remission, Challenges Conventional Care
A ketogenic diet put his ulcerative colitis into complete remission — off all medications, confirmed on colonoscopy. Dr. Nick Norwitz (PhD Oxford, MD Harvard) explains why "evidence-based" care isn't always optimal care, how keto rewires the gut and brain, and...
Longevity Obsession Ignoring Youth Health Crisis
Yesterday I published my latest Substack article and went to bed feeling something was missing. This morning I realized what it was. I had left out two key sections: • One for the hundreds of millions of people with real metabolic dysfunction...
Extreme Glycogen Loading Can Accelerate Breakdown, Not Boost Performance
Is it necessary to follow an extreme glycogen loading protocol? Or will you simply accelerate glycogen breakdown? Read the blog to find out: https://t.co/4tRxNEPTAA https://t.co/Grta1nNNWy
Protein‑rich Breakfast
Big breakfast diet composition impacts on appetite control and gut health: a randomized weight loss trial in adults with overweight or obesity "The HPWL diet was superior to the HFWL diet for suppressing subjective appetite (P=0.003). The faecal microbiota analysis showed beneficial...
Pre‑Sleep Nutrition Boosts Muscle Recovery and Next‑Day Performance
In this live webinar, we will explore whether pre sleep nutrition can affect muscle protein synthesis, glycogen restoration, sleep, body composition, and next day readiness. Find out more: https://t.co/UXBWDt3JIP https://t.co/7uocd3yDXB
Moderate Calorie Restriction Lowers Fat C3, Slowing Aging
Moderate calorie restriction in humans reduces levels of the immune protein C3 in fat tissue, potentially slowing aging and inflammation without the negative effects of severe dieting or weight loss. aging
Optimize Performance: Pre‑Exercise, Sleep Nutrition, and Recovery
Dr Ormsbee will explore: - pre exercise fuelling - pre sleep nutrition - recovery and muscle protein synthesis - glycogen restoration Register here using the early-bird offer: https://t.co/Fg2QSJQ4dC https://t.co/kv7TV7NFxW
Superfoods May Deplete Minerals—Supplements Fill the Gap
What if the superfoods you eat every day are actually stealing minerals from your body? Spinach, kale, sweet potatoes, almonds, and raspberries are all designed by nature to limit how much you consume, and glyphosate-sprayed foods make it worse. That's exactly...
Start High‑Dose Folic Acid Pre‑Pregnancy Cuts Birth Defects 45%
Initiating high-dose folic acid before pregnancy is linked to a 45% lower risk of major birth defects in children of women using antiseizure medication, with no protective effect observed if supplementation begins after pregnancy starts. epilepsycare
Stop Eating Three Hours Before Bed for Better Sleep
One of the simplest things I do for sleep is to stop eating about 3 hours before bed. It's something that’s supported pretty consistently in the research. When you eat (especially a large meal), you’re activating the sympathetic nervous system... not what...
New Delivery Bypasses Diet, Fuels Cells with Urolithin A
Only 30% of people can actually produce Urolithin A from food. And even if you are one of them, you would need six cups of pomegranate juice a day to hit the minimum effective dose. Scientists have found a way...
Wheat Bran Plus Resistant Starch Improves Fecal Health Markers
Combining wheat bran with resistant starch has more beneficial effects on fecal indexes than does wheat bran alone https://t.co/c5q4PlNB2l
No Evidence Vitamin K Shot Causes Jaundice, Cancer
Vitamin K shot - quick facts: * Package inserts # proof of causation. * There is no evidence the vitamin K shot causes jaundice, cancer, or SIDS. * It is not a
When Diet Fails: Iron Infusions for Athletes
Iron deficiency is common among athletes. Under certain scenarios, diet and supplementation may not be sufficient. This blog describes scenarios where iron infusion or injection may be an appropriate treatment option https://t.co/1ybdvV0t1g https://t.co/GQJ8YmacvU
Two-Day Oatmeal Diet Cuts LDL by 10%
Cholesterol: 2-day oatmeal diet may help reduce LDL levels by 10% https://t.co/R0WWUUxAKN via @mnt #CardioTwitter #hearthealth #MedTwitter #health #nutrition
Nutrients Behind Common Ailments Doctors Overlook
WHAT DOCTORS DON'T TELL YOU • Chapped lips: B2, B3, B6 and iron • Dandruff: Zinc, B6 and omega-3 • Headaches: Magnesium and B2 • Constant fatigue: B12, D and iron • Weakness: B1, D and magnesium • Hair loss: Biotin (B7), A and E • Brittle...
Strategic Fuel Station Placement Boosts Carb Intake and Recovery
Something seemingly so simple as putting a fuelling station in the right place can be the difference between players achieving total daily carb intakes or recovering optimally the day before a match. Simple strategy. Big pay-off. tomcoughlin.co.uk #nutritionist #nutrition #performancenutritionist #sportsnutrition
Weight Loss Needs Variety, Not Monotonous Meals
What you think: eating the same thing every day is good for me and helps me lose weight. What I, as a sports dietitian thinks: eating the same thing every day is not sustainable and this person needs to diversify the...
Ketone Ester Adds No Benefit to 120 G/Hr Carbs
Ketone monoester does not offer metabolic advantage when consuming 120 g/hr carbohydrate 🥤 This new study recruited 8 trained male cyclists to a crossover design where they completed 3hr at 95% lactate threshold (LT) followed by 150% LT to exhaustion tests...
Ancient Pomegranate Remedy Validated by Modern Science
Pomegranates have been used by Persian and Greek doctors for thousands of years to improve vitality, and modern science is finally catching up to why. https://t.co/6Ei5AXfk1Y
Three-Day Fast Triggers Free Longevity Boost via Autophagy
The best longevity drug in history is totally free. It's called autophagy. Several things happen when you do a 3 day fast: - your body cannibalizes bad cells / pre-cancer cells / heart plaque - gene expression changes at the 72 hour mark and...
Tart Cherry Juice Speeds Muscle Force Recovery
Tart cherry juice for muscle damage recovery 🍒 This new meta-analysis compiled data from 19 studies (385 participants) which investigated the effects of tart cherry supplementation on muscle damage in athletes 🔍 Here is what they found ⬇️ 💪 Tart cherry juice...
Most Athletes Don't Need Extra Electrolyte Supplements
Electrolytes are heavily marketed to athletes, especially those who notice salty sweat marks during exercise. But do all athletes really need supplements? This blog examines the evidence behind electrolyte use and common claims. Click here: https://t.co/XeKRTTyRpo https://t.co/zX1GrHLJU8