
High‑altitude hypoxia curbs blood‑sugar spikes in mice
A mouse study found that low‑oxygen (hypoxic) conditions cause red blood cells to absorb far more glucose and convert it into a molecule that eases oxygen release, acting as a glucose sink. Mice exposed to 8% oxygen showed markedly smaller blood‑sugar spikes after glucose injections, and the effect persisted after they returned to normal air.
The phase 2 ACCESS trial demonstrated that post‑transplant cyclophosphamide (PTCy) combined with tacrolimus and MMF enables high‑survival outcomes for patients receiving mismatched unrelated donor peripheral blood stem cell transplants. One‑year overall survival reached 86% for donors mismatched at less than 7/8 HLA loci and 79% for 7/8 matches, with low rates of acute and chronic GVHD. The strategy dramatically expands donor availability for Black and Hispanic patients, raising the chance of finding a suitable donor from under 30% to nearly 100% with modest mismatches. Because PTCy uses an inexpensive, decades‑old chemotherapy agent, the approach promises cost‑effective scalability across transplant centers.

A new longitudinal twin study from Germany tracked identical and fraternal twins between ages 23 and 27, finding that intelligence is about 75% heritable. The researchers reported that genetic factors account for 69%‑98% of the link between IQ and later...

Seagrass meadows act as natural coastal armor, anchoring sediment and dampening wave energy. Their dense roots and foliage not only protect shorelines but also lock away significant amounts of carbon dioxide. A 2024 Nature study warned that loss of species...

March has been colorectal cancer awareness month. A reminder of the work of Bert Vogelstein, one of the most cited cancer researchers in history. He showed that colorectal cancer is a slow, stepwise process (often over 20–25 years): normal tissue ➡️...
A new study in the Journal of Geophysical Research shows Earth’s rotation is slowing, lengthening days by about 1.33 milliseconds per century. The slowdown is driven by melting glaciers that redistribute ocean mass, increasing the planet’s moment of inertia. Using fossilized...

New research by Ljiljana Progovac proposes that human language evolved not only for survival but also as a platform for wit, treating quick‑witted wordplay as a sexually selected fitness trait. The theory highlights ancient verb‑noun compounds such as “killjoy” and...

MIT researchers unveiled a myoneural actuator (MNA) that rewires sensory nerves to transform existing muscle into a fatigue‑resistant, computer‑controlled motor for paralyzed organs. In rodent models the MNA restored intestinal squeezing and mimicked residual calf muscle function while sending sensory...

Researchers at Brown University analyzed over 75,000 low‑dose CT scans from the National Lung Screening Trial, covering more than 26,000 participants. They found that about 7% of exams contained significant incidental findings (SIFs) that were cancerous, and roughly 3% of...
Brain imaging shows that reminders of a shared national identity prompt the brain to categorize faces from different ethnic groups more inclusively, while still recognizing ethnic distinctions. This neural flexibility may support social cohesion in diverse societies. neuroscience
Genetically modified marmosets lacking the OTOF gene now serve as the first primate model for human congenital deafness, offering a precise platform to advance gene therapies targeting hearing loss. genetherapy

Archaeologists have identified a 3,000‑square‑meter island off Fiji’s Vanua Levu that is almost entirely composed of shellfish remains. Radiocarbon dating places the formation at roughly 1,200 years old, linking it to a mid‑8th‑century Lapita settlement. The research team dismissed a tsunami...

Robert Bunsen was born OTD in 1811 🎂 The eponymous Bunsen burner was actually constructed for Bunsen by instrument maker Peter Desaga. The burner was essential to the discovery of caesium and rubidium through their emission spectra. https://www.compoundchem.com/2023/03/31/bunsenburner/
I joined Sam Fazeli for the latest episode of Bloomberg Intelligence's Vanguards of Healthcare podcast and talk about our partnership with Eli Lilly and why I believe algorithmic approaches are reshaping the earliest stages of pharmaceutical R&D. The biggest impact...

Scientists at the National Ignition Facility (NIF) announced a historic ignition event on Dec. 5, 2022, producing more energy from a deuterium‑tritium pellet than the lasers supplied. The breakthrough revives optimism for inertial‑confinement fusion, while magnetic‑confinement tokamaks such as ITER continue to...

Researchers at Lund University have unveiled a deep joint‑learning AI model that can simultaneously identify five neurodegenerative conditions—including Alzheimer’s, Parkinson’s, ALS, frontotemporal dementia, and prior stroke—from a single blood sample. Trained on the Global Neurodegenerative Proteomics Consortium’s database of over...

A new analysis highlights that roughly 75 % of the global population has never seen humans walk on another world, making the upcoming Artemis Moon landings the first live experience for most people. NASA’s Artemis program now plans to send astronauts...

Northwestern researchers used precision fMRI to track eight participants as they imagined scenes and inner speech, revealing that imagination primarily engages high‑level transmodal association networks rather than early sensory cortices. Activity during imagined scenarios overlapped with perception in the default...
Astronomers have determined that interstellar comet 3I/ATLAS, discovered in 2025, is likely between 10 and 12 billion years old. JWST measurements of rare isotopic ratios suggest it formed in the early Milky Way, possibly before its parent star system existed. The...
University of Illinois Chicago nutrition professor Krista Varady reported that a six‑hour time‑restricted eating protocol reduced testosterone, lowered free androgen index and improved A1C in a six‑month trial of 76 women with PCOS, while participants lost an average of 10 pounds....
The Manx Wildlife Trust finished planting 30,000 mixed‑native trees on the 105‑acre Creg y Cowin reserve, two years ahead of schedule, thanks to a £38.9 million (≈$48 million) Aviva grant. The milestone marks the first phase of a broader plan to restore...

Scientists have identified pseudaminic acid, a sugar found only on the surface of certain Gram‑negative bacteria, as a vulnerable target. By synthesizing this sugar and creating monoclonal antibodies that bind it, researchers demonstrated in mice that the antibodies flag the...
Scientists at the University of Barcelona Institute of Neurosciences have demonstrated that the novel compound FLAV-27 can reverse cognitive decline in mice engineered to develop Alzheimer's disease. The breakthrough, which targets the brain enzyme EHMT2 to reprogram neuronal epigenetics, offers...

Artemis II, NASA’s first crewed mission to the Moon in over five decades, is slated for launch on 1 April 2026 at 18:24 local time. The European Service Module (ESM) will deploy solar arrays eight minutes after liftoff, provide power and propulsion, and...

Stanford researchers engineered natural killer (NK) and cytotoxic T cells to overexpress metabolite‑sensing G protein‑coupled receptors, most notably GPR183, enabling the cells to home toward tumor‑derived metabolic cues. In mouse models of triple‑negative breast and ovarian cancer, GPR183‑enhanced NK‑92 cells...

Researchers reviewed polysaccharide‑based microneedles as a platform for cancer immunotherapy, emphasizing how additive manufacturing—particularly high‑resolution 3D printing—can create customizable transdermal delivery arrays. Natural polymers such as hyaluronic acid, chitosan and alginate provide biocompatibility and enable dissolvable or hydrogel‑based needles with...
Alamar Biosciences, the Fremont‑based proteomics company, filed to go public on Nasdaq after raising $128 million in a Series C round and adding almost 100 employees in two years. The move marks the firm’s transition from research‑focused labs to commercial sales of...

Physicists are rallying behind a muon collider as the next big step after the Large Hadron Collider, arguing that muon collisions could reach energies unattainable with protons. Although muons decay in microseconds, recent breakthroughs in rapid acceleration and beam cooling...

A recent study by the Institute of Natural Sciences in Brussels examined two fossil whale skulls from Belgium, revealing embedded shark teeth and distinctive bite marks. Micro‑CT scans identified an aggressive bite by the extinct great‑white ancestor *Carcharodon plicatilis* on...

NASA’s Artemis II mission is on track for a 6:24 p.m. EDT launch on April 1, 2026, with the countdown now entering the L‑15H30M window. All non‑essential personnel have cleared Launch Complex 39B and critical pre‑launch activities such as nitrogen inerting and ground launch...

Genetically modified pig livers have entered early clinical testing, with a Chinese patient surviving 171 days after transplantation. Researchers in China are exploring pig livers as auxiliary support, while a University of Pennsylvania team is evaluating extracorporeal pig livers as...

In this episode, Unity Stokes talks with Kim Fisher, Chief Impact Officer of Startup Health’s Food is Medicine Moonshot and Program Director of UC Davis’s Innovation Institute for Food and Health, about the rapid emergence of the food‑as‑medicine movement. Fisher...
A recent scientific review debunked 12 pervasive muscle‑building myths, from elaborate periodization models to the so‑called “anabolic window” and spot‑reduction claims. The authors found that progressive overload, sufficient protein and energy balance, and consistent training volume are the true drivers...

Recent research explains why wildfire smoke in the stratosphere consistently forms anticyclonic vortices. Smoke injected at roughly 15 km rises to 35 km, stretching and intensifying any rotation. While classic theory predicts a cyclone‑anticyclone pair, the study shows that vertical shear can...

Elecoglipron (ECC5004/AZD5004), an oral small‑molecule GLP‑1 receptor agonist, completed Phase 2 trials in type 2 diabetes and obesity, meeting primary endpoints in the SOLSTICE and VISTA studies. AstraZeneca licensed global rights from Eccogene for an upfront payment of $185 million and potential milestones...

NutraIngredients is inviting consumer‑facing, science‑driven startups and researchers to submit entries for its Probiota Pioneers and Scientific Frontiers tracks, with winners presenting at Probiota Americas in Vancouver from June 8‑10, 2026. Startups must be Americas‑based, under 20 employees, founded within ten years...

How did computer science influence cognitive science and vice versa? How did this interaction play a critical role on the path to modern AI? Join Inner Cosmos this week with cognitive scientist Tom Griffiths. eagleman.com/podcast/147

Molecular mechanisms underlying the lifespan and healthspan benefits of dietary restriction across species https://t.co/JodR3q83S7 https://t.co/qUGeAe8A2D
Everything Still on Track for Artemis II Launch to the Moon on April 1 https://t.co/78OHpYtZiS
Inspired by Mother Nature, Discovering New Drugs. @viswacolluru of @lifeschemistry is the latest guest on The Long Run. Sponsored by @AlphaSenseInc and Dash Bio. https://t.co/F01HMam6Ul

With a straight leg, the adductor magnus and gracilis have the longest hip adduction moment arms throughout the normal joint angle range of motion. https://t.co/chzFj9GrBw
Testosterone exposure in the womb creates a male vs female difference in finger length ratios that is also reflected in peoples reported sexual orientation. It’s independent of hormone levels after birth. Dr Marc Breedlove on the Huberman Lab podcast out...
World’s First Surgical Humanoid #Robot Achieves FDA-Cleared Precision in Spine Surgery by @StarSnap_1 #MedTech #Healthcare #HealthTech #Tech #TechForGood https://t.co/aks0DC51ns

The number of 100+ year olds in Okinawa has increased by 4283% from 1975 1975: 29 centenarians 2021 peak: 1271 centenarians Okinawa’s longevity story is generation-specific: people born before WWII had a clear mortality advantage While post-WWII cohorts have had worse mortality than mainland...
Molecular solar battery stores energy for days, yields hydrogen on demand #energysky -- via pv magazine global: https://t.co/uI9nAShJoB

Artemis II Orion spacecraft (built by Lockheed Martin, Boeing and Airbus) is not safe to fly via @idlewords https://t.co/PzojTp2Xt9 https://t.co/sNN96eyWwc
One more day until crew will fly around the Moon for Artemis II! Cameras are set and hands off at the pad 🤞 https://t.co/WwfKVz6YEr

This is a very important study and I'm hearing from clinical experts in my network that the best prevention is calcium, weight bearing exercise and getting regular DXA Scans. Otherwise we're going to see a big increase in high-cost orthopedic...