Transcatheter ViV a Solid Option for Failed Mitral Bioprostheses: SURViV
The SURViV randomized trial compared transcatheter mitral valve‑in‑valve (ViV) with redo surgical replacement in 150 patients with failed bioprosthetic mitral valves, many of whom had rheumatic disease. At one year, ViV showed a markedly lower all‑cause mortality (5.3% vs 20.8%) and fewer disabling strokes. Both groups improved symptoms and quality of life, but ViV patients experienced shorter hospital stays and fewer early complications. Surgical patients maintained better valve gradients, highlighting a trade‑off between early safety and long‑term hemodynamics.
China’s Kinetica-2 Rocket Debuts Successfully, Sending Prototype Cargo Spacecraft to Orbit
Chinese commercial launch firm CAS Space successfully lifted its new Kinetica‑2 rocket into orbit on March 30, delivering a prototype cargo spacecraft and two other payloads. The 53‑meter vehicle can carry up to 12 tonnes to low‑Earth orbit and features a modular...
Study: MRSA Nasal Swab Testing Not Compromised by Mupirocin
A retrospective cohort of 1,034 ICU patients across four Tennessee hospitals found that MRSA PCR nasal swab testing remains highly accurate after mupirocin decolonization. The negative predictive value was 98.8% before treatment and 99.1% when the test was performed within...
J-ENG in Hydrogen-Fueled Two Stroke First
Japan Engine Corp (J‑ENG) has begun hydrogen co‑firing in all cylinders of its 6UEC35LSGH low‑speed two‑stroke engine, the world’s first full‑scale hydrogen engine slated for a 17,500‑DWT merchant vessel. The engine achieved over 95% hydrogen co‑firing at 100% load, confirming...
AAC Clyde Space Expands Orbital Presence with Transporter-16 Launch
On March 30, 2026 SpaceX’s Transporter‑16 rideshare launched 119 payloads, including seven satellites from Swedish‑based AAC Clyde Space. The flight introduced the first two VIREON‑1 and VIREON‑2 Earth‑observation cubesats, delivering 1.5‑meter multispectral imagery for agriculture and forestry. AAC also flew...
In Expanding De Sitter Space, Quantum Mechanics Gets Even More Elusive
Physicists are grappling with the paradoxes of quantum mechanics in an expanding de Sitter universe, where the lack of a fixed boundary prevents conventional measurements. Recent theoretical work suggests that photons could acquire an effective mass in this exponentially expanding space,...
Quantum Physics Can Confirm Where Someone Is Located
Scientists at NIST demonstrated quantum position verification, using entangled photons to prove a prover’s physical location over a 200‑meter baseline. The protocol involves two verifier stations sending random numbers and entangled particles to the prover, whose measurement results are compared...
Inflammaging in Clinical Practice: GlycanAge’s New Data
GlycanAge is translating two decades of glycan research into clinical tools that measure inflammaging, the chronic low‑grade inflammation linked to age‑related disease. By profiling complex sugar structures on proteins, the company offers a long‑term biomarker that differs from short‑term markers...
Discontinuing Beta-Blockers After MI Reasonable in some Patients
The SMART‑DECISION trial showed that stopping beta‑blockers one year after a myocardial infarction is non‑inferior to continuing them in stable, low‑risk patients without heart failure or reduced ejection fraction. Among 2,540 participants followed for a median of 3.1 years, the...
Beyond Glyphosate: Quercus Bio Targets Weeds with Designer Proteins
Herbicide resistance is driving a search for new weed‑control tools, and Quercus Biosolutions is pioneering AI‑designed mini proteins that act like chemicals while offering biological benefits. Using protein‑structure prediction technology from drug discovery, the startup creates proteins that can enter...
WISeSat.Space Expands IoT Constellation with 21st Satellite Launch via SpaceX
On March 30, 2026, WISeSat.Space, the satellite arm of WISeKey International, placed its 21st picosatellite into low‑Earth orbit aboard a SpaceX Falcon 9 rideshare. The satellite extends the company’s secure IoT constellation, which embeds WISeKey’s proprietary Root‑of‑Trust cryptography to protect data...
The Crucial Role of Payload Linker Innovation in the Growth of ADCs
Antibody‑drug conjugates (ADCs) are becoming a cornerstone of oncology, with the global market expected to reach $65.2 billion by 2031. The number of ADC programs has more than tripled, rising from 557 in 2020 to 1,643 in 2025, driven by advances...
The Dosing Problem That Precision Medicine Has Yet to Solve
Only about 45% of cancer patients receive a dose within the optimal therapeutic window, leaving many under‑dosed or over‑dosed. True Dose is introducing an at‑home capillary blood‑spot kit that lets patients collect finger‑prick samples for therapeutic drug monitoring, with results...
Glyphosate: A Common Weedkiller May Induce Anxiety by Disrupting Gut Bacteria
Researchers at the University of Puerto Rico exposed male rats to glyphosate at the EPA’s accepted daily limit of 2 mg per kilogram for 16 weeks. The rats developed heightened anxiety, avoiding open spaces, novel objects, and neutral sounds, while responding...
‘It’s Dangerous, and That’s the Message’: Aussie Study Finds Vaping Likely Causes Cancer
An Australian scientific review concluded that vaping likely increases the risk of lung and oral cancer, marking the most definitive link to date. The analysis relied on short‑term laboratory and human exposure studies because long‑term cohort data are unavailable. While...
York Space Systems Secures PExT Mission Extension Through 2027 Following BARD Success
York Space Systems announced that NASA and Johns Hopkins Applied Physics Laboratory have extended the Polylingual Experimental Terminal (PExT) mission through 2027 after the BARD mission met all primary objectives. The PExT payload, hosted on a York S-CLASS bus, demonstrated...
Kardigan Blood Pressure Drug Proves Hypothesis Despite Split Phase 2 Readout
Kardigan reported that its experimental hypertension drug tonlamarsen achieved a 67% average reduction in the angiotensinogen biomarker after five monthly doses, confirming target engagement. However, the Phase 2 trial showed no statistically significant difference in office systolic blood pressure between the...
Biogen Bounces Back With FDA Nod for High-Dose Spinal Muscular Atrophy Drug
The FDA approved a high‑dose formulation of Biogen’s SMA drug Spinraza, cutting the loading phase from four to two injections and adding a four‑month maintenance schedule. The new regimen, backed by the DEVOTE study, showed significant motor‑skill gains versus sham...
Scientists Just Upended a 300-Year-Old Law of Physics
Scientists at the University of Konstanz have shown that Amontons' first law of friction breaks down for magnetic materials, where friction does not scale linearly with load. By arranging a two‑dimensional array of freely rotating magnets above a second magnetic...
The Scientists Diving Deep Beneath Arctic Ice to Discover the Secrets Below
A Finnish Scientific Diving Academy class recently sent divers beneath a frozen Finnish lake, where participants like Dutch biodiversity adviser Daan Jacobs spent 45 minutes at eight metres depth. The program, now running twice a year, aims to expand the...
Artemis II: Space Weather Forecasting, Monitoring the Sun’s Hazardous Conniptions
NASA’s Artemis II mission will carry astronauts beyond Earth’s magnetic shield on a ten‑day lunar flyby, the first human deep‑space flight since Apollo. A powerful solar flare captured by the Solar Dynamics Observatory on October 3, 2024 underscores the threat of space‑weather events....
New Hope for Children with Severe Epilepsy
Scientists at Manchester University have identified a recessive RNU2‑2‑related neurodevelopmental disorder as one of the most common genetic causes of childhood epilepsy. The condition, which manifests with seizures and severe delays in speech and walking before age one, has been...
Glucose Control in Gestational Diabetes Tied to Offspring Obesity
A large Kaiser Permanente cohort study found that women with gestational diabetes who achieve stable, optimal glucose levels have offspring obesity risk similar to those without gestational diabetes. Women whose glucose control improves slowly or remains suboptimal face 1.3‑to‑1.6 times...
I Discovered the Elusive Chestnut Mining Bee in New York After a Gap of 119 Years
Pollinator ecologist Molly Jacobson rediscovered the chestnut mining bee (Andrena rehni) in a Syracuse chestnut orchard, marking the species' first documented presence north of the Hudson Valley in 119 years. The bee, once thought possibly extinct in New York, was...
March 30, 240 B.C.E.: Halley’s Comet over China
Chinese astronomers recorded Halley's Comet in 240 BCE, the earliest known written observation of the periodic visitor. The *Shiji* chronicles describe the phenomenon as a “broom star” appearing first in the east and later in the north. Modern orbital models place...
Zongertinib a ‘Breakthrough’ for NSCLC with HER2 Mutations
Zongertinib (Hernexeos) received FDA accelerated approval for first‑line treatment of HER2‑mutant advanced NSCLC, based on Beamion LUNG‑1 data presented at the European Lung Cancer Congress. In previously untreated patients (cohort 2), the drug achieved a 76% objective response rate and a...
Psychopathic Traits Are Linked to a Lack of Physical and Emotional Connection During Face-to-Face Interactions
A new study in Cognition and Emotion examined empathy during real‑time conversations among 82 New Zealand participants. While individuals with psychopathic traits could accurately identify partners' emotions, they showed reduced affective sharing and lower physiological synchrony, especially those high in self‑centered...
Multi-Year Field Study Finds that Agrivoltaics Can Support Healthy Potato Yields
A four‑year field trial in northern Italy examined potato production under agrivoltaic (APV) systems with varying shading patterns. The study found that moderate shading (around 20%) caused only a 12% yield drop, while high shading (>35%) reduced yields by more...
Imaging
Edith H. Quimby, a pioneering physicist, established the field of radiation dosimetry in the mid‑20th century. Her methods allowed precise measurement of radiation absorbed by the human body, transforming medical imaging and radiation therapy from guesswork to quantifiable science. The...
New Nature-Published Research Reviews How Metabolic Dysfunction May Be the Core Driver in Psychiatric Diseases
A new review in Nature Mental Health, led by Stanford’s Dr. Shebani Sethi, argues that metabolic dysfunction is a core driver of serious psychiatric illnesses such as schizophrenia, bipolar disorder, and major depression. The paper synthesizes 138 studies linking systemic...
Artemis 2, Project Hail Mary, and the Risks and Benefits of Human Spaceflight
Artemis II is set to launch in early April, sending four astronauts on a lunar flyby that will test systems for a planned 2028 Moon base. The mission coincides with the release of the sci‑fi film *Project Hail Mary*, highlighting public fascination...
Crystal Seed Method Boosts Inverted Perovskite Solar Cells
A research team at the Qingdao Institute of Bioenergy and Bioprocess Technology has introduced a crystal‑solvate (CSV) pre‑seeding technique that precisely engineers the buried bottom interface of inverted perovskite solar cells. The method deposits rod‑like PDPbI₄‑DMSO nanocrystals on SAM‑modified substrates,...
Carbon Nanotube Textile Heaters Push Industrial Gas Systems Toward Electrification
Rice University researchers have created electric heating elements from carbon‑nanotube fibers (CNTFs) that outperform traditional metal‑alloy heaters in gas‑flow applications. By exploiting CNTFs' high specific power loading, lightweight strength and superior thermal conductivity, the team built filament, array and textile‑style...
HKUST Team Advances Vacuum Grown Perovskite Solar Cells
Researchers at Hong Kong University of Science and Technology have shown a fully solvent‑free, all‑vacuum deposition method for perovskite solar cells that delivers a certified 18.35% efficiency on a 0.25 cm² device and 19.3% in the lab. The technique uses lead‑chloride...
Light Responsive Molecules Boost Durable Perovskite Solar Cells
Researchers at the University of Stuttgart and partners introduced light‑responsive, photoswitchable molecules into the grain boundaries of triple‑cation perovskite solar cells. The additive acts as a dynamic buffer, relieving mechanical stress and protecting the crystal lattice under fluctuating light, heat...
Reprogramming Youth: How AI-Engineered Peptides Unlock Longevity Beauty
The article argues that longevity‑focused beauty must move from vague claims to mechanism‑first validation, using the 12 hallmarks of ageing as a roadmap for skin. It positions peptides as the ideal modality because they can precisely modulate the mid‑layer signalling...
Warwick- and Southampton-Led UK Project to Develop Electro-Deposition of Transition-Metal Dichalcogenides
The UK’s EXPRESS programme, a five‑year EPSRC‑funded initiative worth £10.4 m (≈$13.2 m), is led by the Universities of Warwick and Southampton to develop electro‑deposition methods for transition‑metal dichalcogenides (TMDCs). Researchers will combine novel precursor chemistry with electrochemical techniques to grow high‑crystallinity...
These Snakes Steal Poison From Their Prey—Here's How They Know They Have Enough
Red‑necked keelback snakes acquire potent bufadienolide toxins from poisonous toads and store them in neck nuchal glands for defense. A recent study fed wild snakes toxic toads or non‑poisonous frogs, then emptied their toxin reservoirs and simulated predator attacks. The...
Structural Design for Enhancing Performance of 1D Conductive Nanomaterial‐Based Stretchable Strain Sensors
The Small journal review outlines how structural design drives performance gains in stretchable strain sensors that incorporate one‑dimensional conductive nanomaterials such as carbon nanotubes and silver nanowires. It catalogs common architectures—ordered arrays, engineered cracks, wavy or wrinkled films, and mesh...
Vacancy‐Induced Z‐Contrast Anomaly in Self‐Assembled (Ti,V)O2 Heterostructure
Researchers used annular dark‑field scanning transmission electron microscopy (ADF‑STEM) to examine self‑assembled (Ti,V)O₂ heterostructures that form alternating Ti‑rich and V‑rich layers. Contrary to the expected Z‑contrast, the V‑rich layers appeared brighter despite Ti (Z=22) and V (Z=23) having nearly identical...
A SoCal Native Is Set to Pilot NASA’s Lunar Mission — and Become the First Black Person to Reach the...
NASA’s Artemis II mission, slated for launch in early 2026, will send a crew on a lunar flyby—the first human trip around the Moon in half a century. Victor Glover, a Southern California native and veteran Navy test pilot, will serve...
Study: Breath Test Could Transform Microbiome Diagnostics for Clinical Labs
Researchers at Washington University School of Medicine and Children’s Hospital of Philadelphia have demonstrated that volatile organic compounds (VOCs) in exhaled breath mirror gut microbiome activity. Published in Cell Metabolism, the proof‑of‑concept study showed breath profiles could differentiate children with...
Drinking This Daily Can Increase 115 Types Of Good Gut Bacteria, Study Shows
A new analysis of 23,000 dietary respondents linked with over 54,000 stool‑sample genomes shows coffee consumption boosts gut microbial diversity. High coffee drinkers exhibited an eight‑fold increase in the beneficial bacterium Lachnospiraceae asaccharolyticus and a total rise in 115 bacterial...
African Trypanosomes Use a Molecular Shredder to Avoid Detection in the Bloodstream
Researchers at the University of York have identified ESB2, an RNA endonuclease that acts as a molecular shredder within Trypanosoma brucei. By selectively degrading transcripts, ESB2 fine‑tunes Variant Surface Glycoprotein expression, allowing the parasite to evade host immunity. The finding,...
Dreyer’s Nebula
Dreyer’s Nebula is a blue reflection nebula situated roughly 2,700 light‑years away in the Monoceros constellation. Its vivid hue results from nearby hot stars whose light scatters off interstellar dust. The nebula was captured by amateur astronomer Greg Meyer near...
Fraunhofer ISE Uses Industrial Exhaust Gases for Methanol Production – Digital Twin Increases Efficiency by 39 Percent
Fraunhofer ISE demonstrated that metallurgical gases from Thyssenkrupp’s Duisburg steel plant can be turned into methanol in a pilot plant, leveraging a digital twin to fine‑tune the process. Over 5,000 operating hours, the simulation identified optimal inlet temperature, recycle ratio...
The Sky Today on Monday, March 30: Vega Rising
Vega rose above the northeastern horizon just after midnight on March 30, signaling the start of the summer sky for Northern Hemisphere observers. At magnitude 0.0, the star is the fifth‑brightest in the night sky and anchors the Summer Triangle asterism alongside...
Insilico, Tenacia Expand AI-Driven CNS Collaboration
Insilico Medicine and Tenacia Biotechnology have broadened their AI‑driven collaboration to create additional small‑molecule therapies for central nervous system disorders. Building on a March 2025 program that combined Insilico’s Pharma.AI platform with Tenacia’s proprietary data, the partners will use generative...
The Future of Sex as a Biological Variable in Health Research
On Jan. 20, 2025 President Donald Trump signed an executive order that recognizes only two sexes and mandates federal agencies use the term “sex” instead of “gender.” The order abruptly removed the NIH Sex as a Biological Variable (SABV) policy webpages, unsettling...
Why the Lack of Water on Mars Is so Mysterious
Planetary scientists have long agreed that Mars once hosted extensive liquid water and a thick, water‑rich atmosphere. A new comprehensive accounting of water inputs and losses reveals a major discrepancy: the expected ocean depth of 150–250 m at the end of...