Disorder Stops Quantum Systems From Reaching Thermal Equilibrium
What happens when we introduce disorder to a many-body system? In classical physics, we're taught that systems eventually reach thermal equilibrium. However, in quantum mechanics, disorder can prevent equilibrium through a phenomenon known as many-body localization.
Al Gore Highlights Urgent Reality of Climate Crisis
The current state of the climate crisis — Al Gore, opening of @ClimateReality conference https://t.co/NwzUsf36fG
Labor Stress Triggers Hormone Surge That Prepares Newborns
Birth is a stressful event for your baby. That is not a bad thing. It is by design. When your baby goes through labor, their adrenaline and norepinephrine spike to levels higher than most humans ever experience in normal life....
Air Pollution Crisis Hits 129 Nations, Worst in South Asia
With 129 out of 142 countries having air that exceeds WHO safe limits, there is a systemic global air quality crisis, which is most acute in South Asia and the Middle East.
T‑cell Vesicles Deliver DNA, Converting Cold Tumors Hot
In cancer, activated T cells release abundant extracellular vesicles that transfer DNA to the nucleus of tumor and immune (dendritic) cells, turning tumors from cold to hot. An immunotherapy in the works. @Cancer_Cell https://t.co/mHcahijOJC https://t.co/oPT6d7lrFM https://t.co/I0egYxZold
Early Trial RNA‑seq Data: Exciting Yet Requires Caution
🧵 You just got your hands on early clinical trial RNA-seq data. Excited? You should also be cautious. Here's why. 👇 https://t.co/GjA8XIYcVQ
Europe’s Climate Crisis Demands Immediate Solar, Not Net‑Zero Dreams
The WMO just dropped its Europe State of the Climate 2025 report. Here's the reality Big Oil don't want us to look at >CO2 levels are at a 2-million-year high >Europe is warming twice as fast as the rest of the world....
AI Chatbots Capture Poorer Symptom Detail than Doctors
Symptoms reported to an AI chatbot were of lesser quality than reported to a physician, results of a randomized trial of 500 participants across multiple models https://t.co/WXP4R3y9HA https://t.co/l2hLT76AJB
Gender Gap Widens, Not Narrows, in Ultra Marathons
There's a popular idea that the gap between men and women shrinks in ultra running. They reason that women are better at utilizing fat so it equalized advantage. It's a good story. But it's wrong. The gap actually expands slightly in ultra running...
The P‑value Obsession Is Undermining Scientific Progress
🧵 Why the obsession with p < 0.05 is hurting science. A meme. A truth. A reality check. https://t.co/E8rP3MT09w
Urban Growth and Climate Extremes Trigger Flood Tipping Points
"Climate extremes and urbanization drive flood tipping points at the city–river interface" | New article in @Nature PJ Natural Hazards by a team I'm part of at @penn, led by Dingyu Xuan, @dougsjunkdrawer, Hugo Ulloa & others: https://t.co/MuhMXUcRor
High‑dose Semaglutide Cuts Alcohol Use in RCT
Clinicians and patients saw big reductions in alcohol intake when starting GLP-1 medicine. This is the first randomized trial to look at the high dose of semaglutide. There was a study a couple years back looking at a lower dose....
Deep-Sea Golden Orb Revealed as Anemone, Not Alien
If you found this golden orb 2 miles deep, what would you do? The scientists noaa retrieved it using the Deep Discoverer submersible in the Gulf of Alaska. Back in the lab, whole-genome sequencing proved it's not an alien, but a...
How Sugar Fuels Muscles and Becomes CO₂
This blog examines the role of sugar in energy provision. It outlines key biochemical steps, differences between various sugars, and the pathway from carbohydrate intake to its use in muscle and eventual conversion to carbon dioxide. https://t.co/VlAVmqo10d https://t.co/BuINANiHfC
Enzymatic DNA Synthesis Frees Synthetic Biology Design
“You should design for the biology you want to build, not for the process limitations of a supplier that’s been holding the field back.” That line from @Jason_Gammack , CEO of @AnsaBio , gets right to the heart of one...
Maternal Polyphenols Boost Fetal Brain Development in Rodents
New review: The effect of the mother's consumption of polyphenols (resveratrol, curcumin, quercetin, naringin, ferulic acid, genistein) on fetal neurodevelopment in rodents & improvements in brain development 🧠🧠🧠 https://t.co/xN2GISamzy https://t.co/bVFiIjoZem
RCP 8.5 Retired After Years of Implausible Climate Alarm
Back in 2019, I created a Twitter hashtag, #RCP85isBollox, to highlight the danger of building the case for climate action on a wildly implausible scenario. This month RCP 8.5 was finally retired. Read all about it... https://t.co/8grX0nacd6
SpaceX Debris Inadvertently Heads Toward the Moon
SpaceX rocket set for unintentional Moon landing – well, a piece of it anyway https://t.co/9zF8XZYo8x https://t.co/1en6op55tq
Aging Science Promising Yet Still Lacks Core Understanding
Aging biology is full of promise, but the reality is that it's still a nascent field. Great to be back at the @MPIAGE speaking with students and researchers about some uncomfortable truths in geroscience: We still don't understand the drivers of aging. And...
Animal Protein Edge Limited to Older Adults, Leucine Key
Our recently published meta-analysis found that animal-based proteins confer a modest advantage in stimulating muscle protein synthesis (MPS) compared to plant-based proteins (PMID: 42055214). At first glance, this might suggest a benefit to prioritizing animal protein for muscle building. However, the...
Decoding Ovarian Aging to Extend Reproductive Lifespan
Ovarian aging: Mechanisms and strategies to extend reproductive lifespan Core mechanisms include genomic instability, epigenetic noise, mitochondria, inflammation, senescence & fibrosis PhD student Maria Lopez @sinclarfriends is working on it https://t.co/tuJbQb2Xcu https://t.co/K1GlXY4KsY
UCI Paper Reveals How Nutrition Drives WorldTour Cycling Performance
The UCI Sports Nutrition Project paper provides one of the most comprehensive overviews of race nutrition in professional road cycling to date. This blog summarises the key insights and how nutrition science is applied in WorldTour cycling: https://t.co/xmL5ZhgcwM https://t.co/dBgaLhy5cI
Glymphatic Failure Links Dog Dementia to Alzheimer’s
Canine Cognitive Dysfunction and Alzheimer’s Disease: Pathophysiological Relationships and the Impact of Glymphatic System Impairment on Neurodegeneration "...growing evidence suggests that impairment of the glymphatic system is a key pathogenic mechanism in both CCD and AD." https://t.co/1fft2OIrIP
First Psychedelic Experience Alters Human Brain Structure
Very big paper dropping this Tuesday… watch this space… tell your gran… tell your neighbours… “Human brain changes after first psychedelic use” - Nature Communications…
Indian Cows Provide Biogas Solution for Middle East Energy Shortage
The problem with such stories is that such a thing has been going on for years... India's cows offer biogas alternative to Mideast energy crunch https://t.co/PYQSiYYkKx
Photon Teleported 270 M, Advancing Quantum Internet
A photon was teleported across 270 meters in stunning quantum breakthrough “—bringing the quantum internet a big step closer.” https://t.co/ODHtdr0t8b https://t.co/P8MfDzMpG2
Xi Urges Basic Research to Boost China's Scientific Strength
Xi stresses advancing basic research to solidify foundation for building China's strength in science, technology https://t.co/42Xz7m7t1s
Model‑Generated Sequences Don't Prove Viable Bioweapon
None of these guys are getting the real problem here: You can’t identify a “novel bioweapon” by looking at a sequence that some model spit out. You don’t even know if that’s a viable virus. Will it cause disease? Will it...
Invasives Stabilize Soil, Aid Pollinators—Beyond Native Bias
People wrongfully characterize invasive plants: -They stabilize exposed soil -reduce erosion while improving soil structure -provides additional food for pollinators, especially as early succession plants. Mullein is a great example of this, but many of you are too focused on just native plant...
Blood Test Pinpoints Amyloid‑to‑tau Transition in Alzheimer’s
Tracking the turning point in Alzheimer’s disease A blood biomarker reveals the mechanistic shift from amyloid to tau pathology https://t.co/p2UfYwgBHW https://t.co/Kuu82UPrFv
Semaglutide Cuts Heavy Drinking and Cravings in AUD
GLP-1 Drug Semaglutide (Ozempic, Wegovy) Reduced Heavy Drinking & Craving in Adults with Alcohol Use Disorder https://t.co/FYRkjWYhJQ https://t.co/cGtEajk9lp
Calorie Restriction Deactivates Complement C3a, Slowing Inflammaging
"complement C3a reduction is a metabolically regulated inflammatory checkpoint that can be harnessed to attenuate inflammaging" Exoproteome of calorie-restricted humans identifies complement deactivation as an immunometabolic checkpoint reducing inflammaging https://t.co/FxGHE6Obm0
ARPA-H Pursues Bold, Transformative Health Programs
ARPA-H 101: The lifecycle of an ARPA-H program 🗣️"ARPA-H doesn’t settle for iterative results. We exist to change the course of human health. To do this requires bold program ideas and a model unlike traditional funding agencies..." Get to know @ARPA_H https://t.co/iKZKyFcR18...
Twisting Water Molecules Reveal Hidden Four‑Layer Order
Twisting motions of water molecules at the air-water interface create a hidden, ordered structure across four molecular layers, challenging previous models and offering new insight into interfacial chemistry. molecularscience
Birth Weight May Set Lifelong Kidney Endurance Limits
Birth weight may influence how kidneys respond to the extreme physical stress of ultramarathons, suggesting that biological limits to endurance could be shaped from birth. endurance
Unified Redox Strategy Prevents Multiple Diseases Simultaneously
The Simultaneous Prevention of Multiple Diseases: A "One Ring to Rule Them All" Framework for Redox-Driven Health and Longevity https://t.co/TaDq4wbrH7 https://t.co/P8QYDgcmiH
All Major Models Predict Strong El Niño by September
With the update to the CanSIPS models today (CanESM5 and GEM-NEMO) there is now unanimous agreement around an El Nino developing by September, and likely quite a strong one. We will be getting May updates to many of these models...
Ozempic Cuts Drinking in Obese AUD Patients
First randomized trial to show Ozempic reduces alcohol consumption in people seeking treatment for alcohol use disorder. Placebo-controlled, double-blind. Participants with BMI >30 kg/m2. https://t.co/M9Pk2gzKHD @TheLancet https://t.co/OT660QIn6N
Ireland Joins Artemis Accords, Raising Signatories to 65
Ireland will be the next Artemis Accords signatory -- on Monday, May 4, at 3:00 pm ET at NASA HQ. That'll make 65: https://t.co/PmkqAT1O4V
Space Data Centers Soon Normal, Google Joins Elon
Sundar Pichai just said data centers in space will be "the new normal" within a decade. @elonmusk has been saying this for years. When the CEO of Google starts agreeing with Elon, pay attention. The orbital compute era is closer...
Al Gore and Jon Meacham Launch ClimateReality's 20th Anniversary
The @ClimateReality 20th anniversary conference in Nashville commences w/ a conversation between Al Gore and Jon Meacham https://t.co/82gXDav9zm
Super Heavy Oxygen Tank Tested in Repurposed Nosecone
Super Heavy Oxygen header tank in the old nosecone jail. Interesting test going on there. 🤔
China Beats 2030 Solar Target, US Falls Behind
China hit its 2030 solar goal five years early. 90% of new power capacity in China is wind and solar. They've installed 1,500 gigawatts... half of total global solar capacity. Compare to 300 gigawatts in the US. We're falling behind on...
AmfAR Sustains HIV/AIDS Research Amid Funding Cuts
For over 40 years, amfAR has backed research efforts into HIV/AIDS, and is continuing to do so despite government cuts and a widely held perception that AIDS is behind us. Connie Matthiessen Reports: https://tinyurl.com/mr3t6zfa Related IP Resources: Grants for Diseases -https://tinyurl.com/akr4pv9h Grants for Science...
GLP‑1 Drugs Cause Less Muscle Loss than Assumed
Do GLP-1 drugs really cause muscle loss? Turns out perhaps less than what we thought… here’s what you need to know, from: https://t.co/VwrRxnoblW https://t.co/M2RaE1f3EG
Quantum Information Meets High‑Energy Physics: New Caltech Bridge
From dream to reality: The bridge connecting quantum information and matter to high energy physics @Caltech now exists. https://t.co/51b0AAh4K7
AI Beats Doctors in Emergency and Complex Diagnosis Reasoning
An AI program performed better than human doctors on reasoning tasks such as making emergency room decisions and diagnosing complex cases, according to a new study published Thursday in @ScienceMagazine https://t.co/zAeOYW32I4 https://t.co/SGgO3KNfqM
Ida Flood Shows Climate Change Amplifies Urban Flood Risks
"When the Schuylkill swallowed the city: Lessons from Hurricane Ida’s historic flood - New @Penn research shows Ida wasn’t a once-in-a-century anomaly but a preview of how climate change, urbanization & aging infrastructure are rewriting flood risk. https://t.co/F1XFY6fJtV
AI Designs Life Using only 19 Amino Acids
Not something you'd see everyday—changing the alphabet of life. All of life organisms are are built from 20 amino acids. Now genAI is enabling life to be built with 19 amino acids, making isoleucine dispensable. @ScienceMagazine https://t.co/7CBn0Xhuxs https://t.co/tkxtCrFx9Y
Interim PFS Review Confirms Study Continuation
$SMMT ivo HARMONi-3 update on squamous subgroup interim PFS analysis: "At this early interim PFS analysis reviewed exclusively by the Independent Data Monitoring Committee (iDMC), the iDMC recommended that the study continue as planned."