Science Social Media and Updates
Science Social Media and Updates
How do you break psychedelic molecules into parts, like cars in a chop shop, and build new ones? A look into non-psychedelic psychedelic medicine by Clayton Dalton, an ER doc and Ferriss-UC Berkeley Psychedelic Journalism Fellow @ucbsoj & @SciPsychedelics https://t.co/b7R4aTNdyf
1/9 Every bulk RNA-seq experiment I run goes through the same 7 checks before I trust the results. I've been burned enough times to know: if you skip QC, you will find out the hard way. Usually during a meeting with...
Glyphosate exposure, bone mineral density, osteoporosis, and fractures in the United States population 👉"Results are internally consistent and align with existing literature concerning toxicity of glyphosate on bone and extend it to include adverse impact on osteoporosis and fractures." https://t.co/5kJOV4KD1X
Recent neuromorphic computer breakthroughs mean we can now simulate complex physics on brain-inspired chips using 1,000x less energy than supercomputers. We're literally making silicon think like neurons to solve equations that used to require entire data centers. The Cambrian explosion...
Monthly heat records being shattered by an unheard of 10 degrees beyond previous record —> 113F. In March.
Single-dose rapamycin increases brain glucose metabolism but reduces synaptic density in Long-Evans rats [One week after intraperitoneal administration of rapamycin (8 mg/kg) 👨⚕️] https://t.co/6JhcZYS01h https://t.co/wruacgIvFM
An intriguing case of “exceptional resilience” against dementia A 75-year-old man free of dementia despite a dominant Alzheimer’s mutation — and a possible hint for the rest of us https://t.co/lWn9gCKrEm https://t.co/jq0L2NtZ27
The man engineering smarter, healthier babies before they're born: Jonathan Anomaly. This philosopher-turned-biotech founder says the future of your child's health starts at the embryo. Here are 9 things you need to know about embryo selection: https://t.co/XVQF5le4bE
Insulin-like peptide has antagonistic pleiotropic effects on male combat traits and survival traits in an armed beetle https://t.co/7Re0I2vcDW
Pretty big news in the BCI world today. Before Insilico, I was in BCI. I did not expect invasive interfaces to progress so quickly. The future will be amazing and I hope that Elon and Google put some serious muscle...
I teach medical students about neurodegeneration. But a new clinical trial shows the most powerful brain drug might be free. Researchers at AdventHealth put 130 adults (ages 26-58) through a randomized controlled trial: 150 minutes of aerobic exercise per week vs....
Physical activity types, variety, and mortality: results from two prospective cohort studies "Higher physical activity variety was associated with lower mortality. After adjustment for total physical activity levels, participants in the group with the highest physical activity variety score (group 5),...
Leonardo's Brain – a posthumous "brian scan" exploring the secret to his polymathic creativity https://t.co/CV2EyvESBH
Isotonic and minimally invasive optical clearing media for live cell imaging ex vivo and in vivo "Here we develop minimally invasive optical clearing media for fluorescence imaging of live mammalian tissues.... SeeDB-Live minimally affects neuronal electrophysiological properties and sensory responses in...
We massively overestimate how much exercise is needed. Study after study show the benefits for cardio fitness, longevity, and strength come from: 1. Intensity (at very low volume). 2. Consistency. Volume basically doesn't matter beyond a low amount, except for getting...
Parental fasting effects on offspring immune gene expression, epigenetic patterns, and gut microbiota in a species with male pregnancy (Syngnathus typhle) https://t.co/5x9ScJ30uY https://t.co/hixjrq8Bvg
Jerry Coyne comments on Pinker vs. Douthat debate: Do we need God? – Why Evolution Is True https://t.co/adSZcA8oC4
I suspect this will transform our understanding of how species have evolved. Species definitions have always been flawed as they were developed pre-genome sequencing and pre-AI
Does being smart make you less authoritarian and more socially liberal? James Lee (former student), Emily Willoughby, & colleagues present evidence (including ruling out confounds) which suggests the answer is yes. | Predicting political beliefs with polygenic scores for...
Nitric Oxide Signaling and Sensing in Age-Related Diseases "Nitric oxide (NO) is a key signaling molecule involved in numerous physiological and pathological processes within the human body. This review specifically examines the involvement of NO in age-related diseases, focusing on the...
In this thoughtful essay, Garnet Chan reflects on recent progress using classical heuristics in computational quantum chemistry—and what it means for quantum computing. The lessons he draws can help to steer both classical and quantum approaches in scientifically productive directions. https://t.co/XSXMNQTy3b
This is going to be the first year where we get a real look at how the west deals with water scarcity. We’ve had droughts in the past, but this is a glimpse into the future.
Climate change rarely collapses in denial. It unravels in delay. Small postponements compound until the system moves from control to consequence. https://t.co/1l2OM4plnJ
New study of mouse brain aging identifies a progressive drift in cellular identity, consistent with information theory (ITOA) https://t.co/OaB2p9GUgT
Association between cagemate number and risk of death in mice: a time-varying covariate analysis using Cox frailty models "...Female mice exhibited a pronounced increase in mortality rate as cage density declined..." https://t.co/pGtDArEzI0 https://t.co/5gizWZ0QYo
These micro-cages are designed to hold and manipulate tiny cell clusters in miniaturized lab-on-a-chip devices. https://spectrum.ieee.org/lab-on-a-chip-grippers?share_id=9241061
The first human age-reversal trial is officially happening. But before the FDA cleared it, Harvard professor David Sinclair had to pull off a mice experiment most scientists thought was impossible: "These mice had their optic nerve regenerated. We were able to...
#WhatsNext? Scientists in China created ceramics that survive 3272°F, 1800°C! Could revolutionize how heat shields are used by spacecraft. (Engineering Post) #NewMaterials https://t.co/Wr6wLsUfxe
Overexpression of FoxO3a in the dentate gyrus alleviates CUS-induced anxiety- and depression-like behaviors and cognitive impairment https://t.co/p2t18NRkew
Dietary Advanced Glycation End Products (dAGEs): Pathogenesis and nutritional strategies for health longevity-A critical view https://t.co/RrTxgGg4UF https://t.co/ujoKGLKIRz
Epigenetic Clocks, Resilience, and Multi-Omics Ageing: A Review and the EpiAge-R Conceptual Framework The hierarchical architecture of the EpiAge-R framework... https://t.co/YpwDdLI7wo https://t.co/Uid3kNzDHr
Effects of ayahuasca on neuropsychological performance and social cognition: A systematic review - Caio César de Paula, Anna Beatriz Vicentini, Lorena Terene Lopes Guerra, José Carlos Bouso, Jaime E. C. Hallak, Rafael G. dos Santos, 2026 https://t.co/oXP57hmeR1
About time. Atherosclerosis is a lifelong process, and it’s genuinely rewarding to see mainstream recommendations finally begin to catch up with what we in evidence-based longevity have been doing for years. 👨🏻⚕️⚕️
A deadly climate change effect is even worse than feared, study finds” by Doyle Rice for @usatoday: https://www.usatoday.com/story/news/nation/2026/03/08/sea-level-rise-study/89002601007/
A completely novel axis of epigenetic aging. N6-methyldeoxyadenosine (N6medA), i.e. NOT the usual 5 methyl cytosine, increases linearly with age in human prefrontal cortex (r=0.95). Genome-wide profiling reveals age-associated ADENINE methylation changes reminiscent of classic CpG based epigenetic clocks. Abdur...
Engineers have identified mathematical rules behind firefly synchrony in South Carolina swamps, offering insights that could inform swarm robotics and deepen understanding of biological synchronization, such as neuronal and circadian rhythms. biology
Plastic-based wet wipes, often flushed due to unclear labeling, are a significant source of microplastics in rivers, shedding microscopic fibers that may threaten aquatic ecosystems. microplastics
DNA-based tools provide more accurate and responsive detection of inbreeding in wildlife populations than traditional pedigree methods, offering critical insights for effective conservation management and genetic rescue efforts. conservation
Rates of Influenza and Pneumococcal Vaccination and Correlation with Survival in Multiple Myeloma Patients [Dec 6, 2022] @mtmdphd et al. @AjaiChari CLML https://t.co/kUQeRmdKWV #NCT02761187 #mmsm #IDonc #ClinicalTrials #caxtx https://t.co/L7r9caCcGN
Discontinuation of maintenance therapy in multiple myeloma guided by multimodal measurable residual disease negativity (MRD2STOP) - @bdermanmd et al. @ajjakubowiak #ASCO24 Abstract 106 https://t.co/FBTY7SnCxK #NCT04108624 #mmsm #mmMRD
Clinician attitudes and practices toward measurable residual disease in multiple myeloma [Jun 7, 2020] @bdermanmd @jagoda_jasielec @ajjakubowiak Brit J Haematol https://t.co/8zhxYfYwZQ #mmsm #mmMRD https://t.co/QTlR2gv5Q0
Consumption of coffee and tea and the risk of developing neurodegenerative diseases: a cohort study in the UK biobank https://t.co/bv0q79xKni
What if we could use technology to identify wildfires, then extinguiwh them before they spread? That’s what Crossfire, a research team, is trying to accomplish with drones. There’s a multi-million dollar contest awarding the best wildfire-dousing tech. #wildfire #drones #tech #fire
Alright, Alice 24-0001 petunia bits co-culturing with Agribacterium strain Gv3101 carrying a PcUBI4::RUBY::THSP construct. Testing out this ubiquitin promoter for stable transformation to avoid silencing. These will bake at 30°C until Monday and then transfered to selection. 🤞 https://t.co/SO1EKELMgU
NAD⁺ as a central hub regulating the hallmarks of aging: Mechanisms and therapeutic implications https://t.co/Mw45GF0QhL https://t.co/pvAGRxXQZv
Shiyan 30-03, 30-04 and the CZ-2D upper stage cataloged in 587 x 593 km x 35.0 deg orbits following their launch on Mar 12. No orbit data yet for SatNet-LEO12 or Tenkoh-2.
If avoiding sugar, consider stevia. A stevia plant extract (from Pharmingen, Korea) improved muscle metabolism, mitochondrial function, and attenuated muscle loss in obese mice while activating SIRT1. Non-ultraprocessed stevia resembles matcha powder 🍵 https://t.co/tWvBmZzk2g
Resilience is physiological & actionable: Spiking your morning cortisol increase (which is what wakes you up & is healthy) with bright sunlight & exercise, shortens the duration and the amplitude of the cortisol response to afternoon and night time stressors,...
The once bold idea that treating aging will treat chronic diseases (which some refer to as the Geroscience Hypothesis) is about as innovative today as the round Earth hypothesis
Syringic acid is a naturally occurring molecule in grapes, olives, pumpkins & herbs with antiinflammatory, anti-microbial & anticancer properties. New study finds it prevents rodent neurotoxicity & inflammation. Not yet sold widely but will be I expect https://t.co/3XtSesFb9I https://t.co/C3RqjvK6NY
