Digital Twins Will Accelerate Drug Development via Virtual Trials
How digital twins and in silico clinical trials can change the future of drug development https://t.co/lEhJNwrSlH
Don't Reinvent Broken Wheels—Use Existing Bioinformatics Tools
1/ Bioinformaticians: Before you heroically code your own method... STOP. You might be about to reinvent a very broken wheel. https://t.co/c4FT7VXeM6
Climate Change Drives Rising Cost of Living
The impacts of a warming world are showing up in the cost of living https://t.co/NCbm8TnOL6
T‑cell Engagers Need Missing Design Tricks for Success
With the rise and rise of ADCs, T cell engagers have taken something of a back seat of late. What if the bigger problem is some of them may be missing a key trick? Here we highlight some design...
Wheat Needs Adequate Moisture to Fill Out Grain
Without sufficient moisture from rainfall or irrigation, wheat shoots struggle to fill out and produce grain https://t.co/v386ZS45Pu
Renewable Power Powers Rainforest Communities, Replaces Diesel
Clean energy projects are taking off across the rainforest, reducing the need to burn diesel and bringing 24/7 power for refrigeration, schooling and tourism. Read more: https://t.co/ZgEIVqLCT0 📷: Michael Dantas/Bloomberg https://t.co/0qfYM2XWn4
Vaccination and Boosters Are Key to Preventing Long COVID
The best way to prevent long Covid is through vaccination and annual updates or boosters https://t.co/m56zh2o2ZY
Chromosomal Abnormalities Impact Myeloma Survival Differently Across Populations
Population differences in the associations between chromosomal abnormalities and overall survival of multiple myeloma [Jan 31, 2025] Bei Wang et al. @Bloodneoplasia https://t.co/IFPgCwpGo6 #mmsm #PrecisionMedicine #cancerdisparities https://t.co/vpNoEupRPG
High CTC Levels Signal Aggressive, Genomically Complex Myeloma
Elevated circulating tumor cells [#cactc] reflect high proliferation and genomic complexity in multiple myeloma [Sep 23, 2025] Garces et al. @Hemasphere_EHA https://t.co/R8ehW89gTn #mmsm #cagenome https://t.co/Ms6SGwbxcL
Cold Plunge Activates Vagus Nerve, Cuts Inflammation
Are you a cold plunge person — or does the idea make you want to close the app? For the full 10percenthappier podcast episode with Dr. Kevin J. Tracey — neurosurgeon, president and CEO of the Feinstein Institutes for Medical Research,...
CRISPR Therapy Cuts Swelling Attacks 87%, 60% Attack‑Free
$NTLA Intellia says CRISPR-based treatment for rare disease reduced swelling attacks in pivotal trial Attack rates dropped 87%, relative to placebo. Just over 60% were entirely attack-free over the period, compared to 11% for the placebo patients. https://t.co/ljPC7Lww0D via @Jasonmmast
Oruka's Long-Acting Psoriasis Drug Achieves 63% PASI‑100
$ORKA Oruka’s long-acting psoriasis therapy posts strong results in mid-stage study 63% PASI 100 score at 16 weeks, very strong data. https://t.co/RJxnbuU0e3 via me
New Book Chronicles Sickle Cell's History and Cure Quest
📢My new book is out on Sept 8th from @Harvard_Press: 'Curved Air: A Biography of Sickle Cell Anemia and the Quest to Cure the First Molecular Disease.' Some early testimonials.... @EricTopol @PeterHotez https://t.co/o3DKXW7d8t #sicklecelldisease https://t.co/4yrsbdDFe0
Veradermics' Hair Loss Drug Clears Late-Stage Trial
Ok, here we go... $MANE Veradermics' hair loss drug succeeds in late-stage trial. A report from @ADeAngelis_bio https://t.co/jtSB36sPGO
Fatty Liver Disease May Hit 1.8 Billion by 2050
Fatty liver disease could affect 1.8 billion people by 2050 in a growing health crisis: https://t.co/NTYTCrCwF9 #health #fattyliver #disease #research
Texas Researchers Claim Breakthrough for Younger, Stronger Brain
Want a Stronger, Younger Brain? Texas Researchers Say They Have Made a Fascinating Breakthrough https://t.co/FlYc78CxM7 #brainhealth #research
Data Centers Face Scrutiny over Rising Water Consumption
Data centers are under fire for their voracious electricity use. Now communities are worried about their water use as well as we head into a dry summer. https://t.co/6fnM7j9dsT
Key Insights Await From Tovecimig Companion-002 Data
$CMPX data from Companion-002 study of tovecimig coming before 8am ET today. What to look out for, via @ByMadeleineA -> https://t.co/6IDCqMyNPE
Heart‑Metabolic Risks Accelerate Cognitive Decline in Indian Seniors
Cardiometabolic-Inflammatory Risk Factors and Cognitive Decline Among Older Indians—Report From a Nationally Representative, Longitudinal Study 'Longitudinal data provided by LASI-DAD study shed light on how cardiometabolic risk factors may influence decline of cognitive function and development of dementia in older adults...
Graphene Filter Traps and Kills Bacteria
📰 🧪 James Tour Group in the News: Bacteria trapped — and terminated — by graphene filterAn article features Rice research that developed a technique to turn laser-induced […] https://t.co/mYg3jfcPzP
New Neuroplasticity Enables Learning From One Experience
"Recently, neuroscientists described a new form of neuroplasticity that might be helping the brain learn across a timescale of several seconds — long enough to capture the behavioral process of learning from a single experience." https://t.co/RqqhfSDgWb
Infrasound Triggers Stress Hormones, Explains ‘Haunted’ Feelings
Exposure to infrasound—sound below the range of human hearing—can elevate cortisol levels and increase irritability, offering a scientific explanation for mood shifts often attributed to paranormal experiences in certain environments. infrasound
MicrobiomDigest’s Eagle Eye Catches Transposed
Such blatant chutzpah; reminds me of the transposed western blots and path slides @MicrobiomDigest is such an eagle eye at spotting...
Uridine Boosts Synapse Formation in Aging Brains
Nutritional modifiers of aging brain function: use of uridine and other phosphatide precursors to increase formation of brain synapses https://t.co/bOoaNebYmn
Air Pollution Fuels Sarcopenic Obesity via Inflammation
Air pollution and muscle-fat imbalance: How PM2.5 components and ozone drive sarcopenic obesity through inflammation "This study provides novel insights into environmental triggers of SO, highlighting the need for integrated air quality policies targeting specific PM2.5 components and personalized prevention strategies...
Cherry Blossoms Bloom 12 Days Earlier, Linked to Fossil Fuels
Japan: Diarists have chronicled the comings and goings of cherry blossoms each year since AD 812 Kyoto cherry trees' peak bloom dates tumbled 12 days since the 19th century to dates unseen in at least 1,200 years - in perfect correlation...
Mapping Genomic Landscape of Multiple Myeloma Precursors
Genomic landscape of multiple myeloma and its precursor conditions [May 21, 2025] Jean-Baptiste Alberge et al. @IrenemGhobrial @NatureGenet https://t.co/DDWGRrpI4Y #mmsm #PrecisionMedicine #cagenome https://t.co/X0OPLHNkdG
Multiple Myeloma Evades GPRC5D T‑Cell Engagers via Multim
Multimodal antigenic escape to GPRC5D-targeted T cell engagers in multiple myeloma [Jan 15, 2026] @hollyleeYJ et al. @NBahlis @NatureMedicine https://t.co/mz393mPMAq #mmsm #PrecisionMedicine #tcellrx THREAD: https://t.co/lNX9b7LsnR HT @AuclairDan https://t.co/d0JNE6pb5x
Uridine Shields Neurons by Activating Mitochondrial K⁺ Channel
The Protective Effect of Uridine in a Rotenone-Induced Model of Parkinson’s Disease: The Role of the Mitochondrial ATP-Dependent Potassium Channel https://t.co/jBlSlgedWo
Engineering Immortality: AI Challenges Death as System Failure
The New York Times says wanting to live is pathological. What do you think? Two thirds of the human population believes in some form of life after death. Ancient Egyptians built pyramids for it and Gilgamesh searched deserts for it. 1.9 billion...
Q-Day Could Arrive Within 3‑7 Years, Not Decades
Everyone's asking when Q-Day is. That's not the right question. Everyone wants the Q-Day date so they can plan backwards. But can change your cryptography at all, and fast? Some data from a recent Project Eleven (@projecteleven, @apruden08) presentation on Q-Day modeling: -...
Ageing Is a Multilevel Network; Target Central Hubs
Ageing was never a singular problem in biology: implications for mechanisms, measurements and interventions 👉 “Because molecular, cellular, tissue and organismal levels retain partial autonomy, human ageing can be viewed as a multilevel phenomenon. 🔬Geroscience may therefore advance by mapping this network...
Epigenetic Clocks Predict Lung Cancer Risk Beyond Self‑reports
New paper: Epigenetic age clocks help predict lung cancer risk & mortality by estimating smoke exposure. Is independent of self-reported smoking history, so people probably lie about it. Clocks could help doctors predict lung cancer risk & decide on...
Crab Nebula Named for a Mistaken Visual Impression
Why is it called the Crab Nebula? Not because it actually looks like a crab — but because someone thought it did. In the 1840s, the Earl of Rosse sketched the wispy filaments of this supernova remnant and said they looked like...
Newborns Recognize Native Language Rhythm Within Days
Your baby can tell the difference between languages within days of being born. In studies, newborns less than two days old sucked differently on a pacifier depending on whether they were hearing their native language or a foreign one. They...
Blocking Gut “Signal Two” Expands Tregs, Curbs IBD
Blocking immune 'signal two' in the gut expands a specialized regulatory T cell population, suppressing intestinal inflammation and suggesting a new therapeutic approach for inflammatory bowel disease and related autoimmune conditions. immunology
Pandemic Caused by Zoonosis, Not Conspiratorial Architects
Nonsense. There were no “architects of the last pandemic,” predictions rely on scientific evidence of zoonotic spillover due to climate change/deforestation. But pushing anti-science propaganda or wellness products depends on demonizing real scientists, it relies on their end-user’s gullibility
Raw Peptides Degrade Instantly, Never Achieve Effect
Hi @MartinShkreli - if as you say at https://t.co/qJh2vgV0Wm that "raw peptides have a half-life measured in seconds or minutes, meaning your body destroys them almost instantly after you inject them. They never get a chance to do anything."...
MIB‑626 NMN Shows Lifespan Boost and New Mechanism
1. No living forever 🙈 2. Some MIB-626 (crystaline polymorph, pure NMN) human clinical trial results are in 😀 3. About to resubmit a revised mouse MIB-626 paper with Alice Kane, showing improved health measures + lifespan & a putative new mechanism...
NTLA Set to Unveil First In‑Vivo CRISPR Phase 3 Data
Here is a video of me entering my office tomorrow knowing that $NTLA is about to present the first-ever Phase 3 data of an In Vivo (!) CRISPR Gene Editing Program. Somehow - and after @adamfeuerstein’s🧵👇- I have a feeling...
Allulose and Tagatose Lower Post‑Meal Blood Sugar
Glycemic and Cardiometabolic Effects of Rare Sugars Allulose and Tagatose: A Systematic Review and Meta-Analysis of Controlled Human Intervention Trials 👉"Supplementation of allulose or tagatose attenuates postprandial glycemic and insulin responses..." https://t.co/nqQTlk20m4 https://t.co/jRzp9Hrssy
V‑Formation Reveals Graceful Physics of Vulnerability
Grace against gravity and the physics of vulnerability – fascinating and surprisingly moving read on how birds fly and why they flock in V-formation https://t.co/Y26uEvvYCn
Combat Smoke Inhalation Triggers Neuroinflammation, Threatening Brain Health
The impact of military occupational combustion smoke inhalation on neuroinflammation and brain health https://t.co/uMsiMyonkA https://t.co/3nXZ7etBPs
Celebrating 61 Years of FFT: MIT’s Classic Breakdown
61 years ago this month, the Fast Fourier Transform was created, a powerful tool for image compression & data analysis. Watch a classic MIT breakdown of FFT, perhaps the most-taught algorithm at the Institute: https://t.co/R7zdspBswx v/@MITOCW https://t.co/lVabrS3syd
Domain Walls Stay Stable; Demagnetization Happens Locally
Ultrafast imaging reveals that magnetic domain walls remain highly stable under intense laser pulses, indicating that demagnetization occurs locally rather than through rapid boundary movement—an advance for faster, more efficient data storage. nanomagnetism
Light Pollution Endangers Atacama's World‑Class Dark Skies
Light pollution threatens the Atacama Desert’s uniquely dark skies, endangering one of the world’s premier sites for astronomical observation and critical research into the origins of the universe. lightpollution
Ergothioneine Ties Blood Metabolome To
Ergothioneine. The blood metabolome of cognitive function and brain health in middle-aged adults – influences of genes, gut microbiome, and exposome https://t.co/H8tWyRhswR
Micron‑scale Chip Projects Images Onto Sub‑egg‑cell Area
Engineers have created a 1-square-millimeter chip that can project a photograph onto an area smaller than the size of two human egg cells. This precise laser control could have applications in augmented reality, biomedical imaging, and quantum computing. https://spectrum.ieee.org/mems-photonics
Heat Therapy Mimics Exercise Through Shear Stress and Genes
Best review yet: We have identified plausible ways heat therapy works, such as shear stress and heat-sensitive genes “We find heat therapy to be analogous to exercise in many respects” 💪 https://t.co/RAFMTK8j3S https://t.co/iTVyZZuFZc
Midlife Fitness Proven to Boost Longevity and Health Span
A new JACC study from the Cooper Institute (April 22, 2026) followed nearly 25,000 adults for 30 years. As a medical school professor, I teach that the strongest longevity drug we have is not on a prescription pad. This study makes...