Vir Biotechnology Inc (VIR) Q4 2025 Earnings Call Transcript
CVRx reported fourth‑quarter 2025 revenue of $16 million, a modest 4% rise, while gross margin improved to 86% driven by higher selling prices and manufacturing efficiencies. The company added 13% more active implanting centers, reaching 252, and expanded U.S. sales territories to 53. A landmark BENEFIT HF trial was launched, targeting 2,500 patients and potentially tripling the addressable market to $30 billion. Guidance for 2026 projects $63‑67 million revenue, with ample cash and a debt facility extended to 2031.
GeneDx Holdings Corp (WGS) Q4 2025 Earnings Call Transcript
GeneDx Holdings reported Q3 2025 revenue of $116.7 million, a 52% year‑over‑year increase, driven by a 66% jump in exome and genome revenue to $98.9 million and 25,702 tests performed. Adjusted gross margin rose to 74% as higher reimbursement rates and a...
AI & Data Security: Insights From IBM’s Chief Architect
IBM’s Chief Architect Devan Shah outlines how the company’s OnePipeline platform now supports over 450 developers by shifting from Travis CI to Tekton and Argo CD, trading longer build times for automated security scans. He details the internal AI coding assistant...
Your Phone Clutter Is Hurting Your Productivity
The article argues that phone clutter—unused apps and poorly organized screens—directly hampers productivity by adding friction to information retrieval. It defines phone clutter, illustrates the cost of searching through multiple screens, and offers a step‑by‑step approach: purge unused apps, optionally...
Summit Therapeutics Inc (SMMT) Q4 2025 Earnings Call Transcript
Summit Therapeutics reported a strong cash position of $713 million with no debt at the end of 2025, while GAAP operating expenses fell to $225 million despite a rise in non‑GAAP R&D spend. The FDA accepted the Biologics License Application for ivonesumab...
Myriad Genetics Inc (MYGN) Q4 2025 Earnings Call Transcript
Myriad Genetics reported Q4 2025 revenue of $209.8 million, essentially flat year‑over‑year but above its pre‑announced range, while test volume rose 2% to 382,000. Strong double‑digit growth was seen in MyRisk hereditary cancer (14% affected, 11% unaffected), Prolaris prostate cancer (12%...
Hims & Hers Health Inc (HIMS) Q4 2025 Earnings Call Transcript
Hims & Hers Health reported Q4 2025 revenue of $171 million, a 46% year‑over‑year increase, and full‑year revenue of $588 million, up 51% and ahead of guidance. Gross margin rose to 85% in the quarter and 83% for the year, while operating...
Tarsus Pharmaceuticals Inc (TARS) Q4 2025 Earnings Call Transcript
Tarsus Pharmaceuticals reported record 2025 net product sales of $451.4 million, driven by XDEMVY adoption, and issued its first full‑year 2026 guidance forecasting $670‑$700 million, implying over 50% revenue growth. The company highlighted a 44% gross‑to‑net discount, a robust DTC campaign that...
Ivanhoe Electric Inc (IE) Q4 2025 Earnings Call Transcript
Enphase Energy reported Q4 2025 revenue of $343.3 million, with U.S. sales representing 89% of the total and a 13% sequential decline in U.S. revenue and a 29% drop in Europe. Gross margins fell to 46.1% non‑GAAP and 44.3% GAAP, largely...
Freshpet Inc (FRPT) Q4 2025 Earnings Call Transcript
Freshpet reported Q4 2025 net sales of $285.2 million, an 8.6% year‑over‑year increase, and full‑year sales of $1.102 billion, up 13% despite a slowdown in the overall pet‑food category. Adjusted EBITDA rose 16% to $61.2 million and adjusted gross margin improved to 48.4%,...
HealthStream Inc (HSTM) Q4 2025 Earnings Call Transcript
HealthStream reported record Q3 2025 results, posting $76.5 million revenue, a 4.6% year‑over‑year increase, and new highs in operating income, net income and adjusted EBITDA. Subscription revenue rose 5.7% driven by strong CredentialStream, ShiftWizard and Competency Suite growth, while legacy product...
Metrics that Matter: How to Prove the Business Value of DevEx
Developer experience (DevEx) is emerging as a measurable driver of business performance, not just a cultural nicety. Studies show firms with best‑in‑class tools grow revenue 4‑5 times faster and deliver 60% higher shareholder returns. Core metrics—DORA indicators, flow efficiency, and...
Backblaze Inc (BLZE) Q4 2025 Earnings Call Transcript
BlackLine reported Q4 2025 revenue of $183 million, an 8% increase year‑over‑year, and total ARR of $702 million, up nearly 10%. Bookings surged 22% to a record level, with three‑quarters coming from existing customers, while platform pricing adoption rose to 11% of...
This AI Can Improve Your Peer Review — and Make It More Polite
Researchers at Stanford introduced the Review Feedback Agent, an AI coach that leverages five large language models to improve peer‑review comments. In a test on roughly 20,000 reviews for the 2025 ICLR conference, the system flagged vague, unprofessional, or fact‑incorrect...
What Can’t You Say on TikTok?
In this episode, host David Ruiz talks with Malwarebytes senior social media manager Zach Hinkle and content creator MinJi Pae about the sudden technical glitches on TikTok after its ownership transferred to American stewards, which many users interpreted as censorship of...
Ensure Auditors Have Full Data Before Trusting Their Feedback
Be careful of getting "audits" This comes from someone whose agency does 10-15 audits a week for prospective clients. It's very "easy" to find things wrong or find improvements if you don't have all the data, learnings, or inside info. Make sure...
Global Climate Momentum: Renewables, Net‑Zero Cities, and Record Cuts
Good climate news this week 1 China: Country’s emissions have been flat or falling since March 2024 2 Brazil: Amazon deforestation on pace to be the lowest on record 3 Chile: Country’s electric system hits historical participation of 93.5% of solar and wind...
Large Language Model Reads Radiologists' Notes to Flag Patients for Follow-Up Imaging
Researchers at Parkland Health created an AI‑powered tool that leverages a pre‑trained large language model to read radiologists' free‑text notes and automatically flag patients needing follow‑up imaging. In testing on 130,000 studies, the model identified 97% of imaging recommendations and...
All Hail Purse Computer, Halide App Review, Google Pixel 10a, Samsung Galaxy AI Teasers, Special Apple Experience, Nothing Launch Event,...
In episode 467, host Tnkgrl and Verge writer Allison Johnson dissect the latest mobile tech, championing the innovative Purse Computer concept and praising the Halide camera app’s new Process Zero features. They critique Google’s underwhelming Pixel 10a, anticipate Samsung’s expanding...
AI Can't Replace Enterprise-Scale Security Platforms Like CrowdStrike
Can AI replace security platforms? I asked Claude to build a CrowdStrike replacement. Claude: "I have to be straightforward: building a replacement for CrowdStrike isn't something I can do here. CrowdStrike is a massive platform built by thousands of engineers over...
Nintendo Pre-Order Updates – February 22, 2026 – Rayman, Xenoblade X on Switch 2, Scott Pilgrim EX, More
Nintendo’s February 22 2026 pre‑order roundup reveals a robust launch slate for the Switch 2 and the legacy Switch across the United States, Canada, and the United Kingdom. The lineup kicks off on Feb 27 with multiple Resident Evil bundles and spans over 60...
CEO Interview with Juniyali Nauriyal of Photonect
Photonect, a Rochester‑based photonics startup founded by CEO Juniyali Nauriyal, is commercializing a laser‑fusion, epoxy‑free fiber‑to‑chip attachment process. The technology, built around an oxide mode converter, lifts coupling efficiency from roughly 50 % to 80 % and cuts optical loss to under...
I Started Using a Self-Hostable AI Research App and I Should Have Sooner
Raghav Sethi reviews Khoj AI, a self‑hostable research assistant that fills the gap between lightweight chat tools and heavyweight platforms like NotebookLM. The service offers a free web tier powered by Gemini Flash 3 and a Docker‑based self‑hosting option that can...
Are Costco's Kirkland AA Batteries Better Than Energizer?
Costco’s Kirkland alkaline AA batteries have been shown to match or exceed Energizer’s standard and Max alkaline models in independent tests while costing significantly less. Consumer Reports and YouTube reviewers such as Project Farm and Lumencraft recorded longer runtimes for...
HEO and UNSW Partner for Australia’s First Active Propulsion RPO Mission
HEO and UNSW Canberra Space have teamed up to launch Australia’s first rendezvous and proximity operations (RPO) mission that employs an active propulsion system. The project uses the recently acquired Continuum-1 satellite as an in‑orbit testbed to validate fuel‑efficient maneuver...
Adyen Shares Drop Up to 20% Following Cautious Outlook for Future Growth
Adyen posted H2 2025 net revenue of €1.27 billion, a 17% year‑over‑year rise, and total processed volume of €745 billion, up 19% excluding a major client. EBITDA grew 23% to €702 million, delivering a 55% margin, while full‑year 2025 revenue reached €2.36 billion. The company’s...
Geothermal Must Add 2GW/Yr to Hit 10% by 2040
Geothermal could be 10% of US electricity production by 2040. To hit 10% in 15 years, you need to start with 400MW of new geothermal this year and scaling deployment to 2GW per year by 2030 and then by 10%...
I Finally Gave up on My "Smart" TV and Bought a Streaming Box Instead
After years of frustration with sluggish smart‑TV platforms, the author replaced the native interface on a Hisense set with an Apple TV 4K (3rd gen). The $170 streaming box delivered markedly faster app launches, cleaner navigation, and seamless integration with existing Apple devices....
Neuro-Symbolic AI and the Quest for Trusted Intelligence in Professional Sectors
Neuro‑symbolic AI merges deep‑learning intuition with symbolic logic, addressing the strict reasoning demands of legal, medical, and financial workflows. By 2026 hybrid models verify outputs against hard‑coded rules, delivering trustworthy, compliant results. The approach powers automated legal discovery, precision medicine...
Beyond Nodes: Hybrid Neural 3D Engines Lead AI Creation
Nodes aren't the future of AI creation. Here's what comes next. 0:00 - Nodes aren't the future 0:32 - The viewport problem 1:38 - Plumbing vs filmmaking 2:40 - No viewport; just a slot machine 3:22 - Stacks, nodes, and spatial engines 5:02 - New...
Yotta’s Fraud Suit Against Evolve Bank Dismissed by San Francisco Judge, Provisionally
A San Francisco federal judge dismissed Yotta Technology’s fraud lawsuit against Evolve Bank & Trust, citing procedural deficiencies and the indispensable‑party rule. The ruling hinges on the bankruptcy of Synapse Financial Technologies, the middleware that linked Yotta’s prize‑linked savings app to Evolve’s...
Mississippi Healthcare System Shuts Down Clinics After Ransomware Attack
The University of Mississippi Medical Center (UMMC) suffered a ransomware attack on February 19 that crippled its Epic EHR, IT network, and phone systems, forcing the shutdown of nearly 30 clinics and a shift to paper‑based documentation. Vice Chancellor LouAnn...
Red Rooster Champions Australia’s Heartland in New Brand Campaign via Leo Australia
Red Rooster, Australia’s first chicken shop, has unveiled a sweeping brand campaign developed with Leo Australia. The rollout features two 30‑second TV commercials, shorter cuts, and a full suite of social, digital, OOH, PR and in‑store assets. Filmed in authentic...
QLD Building Commission Moves IT Under Operations
The Queensland Building and Construction Commission (QBCC) has reorganised its digital and information division under a newly appointed chief operating officer, Amanda Pafumi, replacing the former CDIO role with a general manager, digital and information. This shift integrates technology functions into...
From Weeks to Minutes: Streamlined AI/DS Workflow
❌Most data science projects take 4 weeks because of meetings, reruns, and handoffs between teams ✅A good AI/DS workflow compresses it to ~15 minutes. I’m demo-ing how to do it live (free): https://learn.business-science.io/registration-ai-workshop-2
Users Unaware Funds Are Held at Evolve, Echoing SVB Lessons
I wonder how many end users of certain products/services built on Stripe and Airwallex realize funds are held at Evolve. It's almost like no one learned anything from SVB failing because the gov't bailed out uninsured depositors. https://t.co/024w8yneu7
This One Tool Will Help You Master the Android Terminal Emulator Termux
How‑to‑Geek’s Faisal Rasool introduces "termai," a command‑line tool that embeds Google Gemini or OpenAI’s ChatGPT directly into the Android terminal emulator Termux. By typing a simple "ai" command, users can retrieve exact shell commands, generate Bash or Python scripts, and...
Silbat Silicon Batteries Ensure 14-Day Uninterrupted Power
Silbat silicon batteries guarantee uninterrupted power supply for 14 days #energysky -- via pv magazine global: https://t.co/83tK1ZQ0hg
Copilot Bypassed Labels, Accessed Confidential Emails Despite DLP
Microsoft Copilot ignored sensitivity labels twice in eight months — and no DLP stack caught either one https://t.co/tVaHZLzT8E "For four weeks starting January 21, Microsoft's Copilot read and summarized confidential emails despite every sensitivity label and DLP policy telling it not...
AI B2B Lead Generation: 7 Strategies I Use to Book Meetings
The article outlines seven AI‑driven tactics that let B2B sales teams locate, qualify, and outreach to prospects faster than manual methods. It highlights AI tools that can parse 800M+ contacts, generate personalized email sequences, score intent signals, and automate reply...
Define Goals and ROI for Successful Tech Projects
Technology initiatives, like ERP or CRM, require a clear purpose, defined parameters, and managed ROI. Define your goals, expectations, and project management for success. #TechTips #ProjectManagement https://t.co/hPBuiNsgQ8
Unscripted Dive Into Zoho ERP, AI, SaaS Future
ZohoDay 2026 - the unscripted podcast review with Brian Sommer https://t.co/ZDIW0WioZc -> brianssommer and I grab a deserted room, start the countdown timer, and look to make sense of Zoho ERP, the AI stack, and the debated future of SaaS -...
AI Adoption Slower Than Expected, Short‑Term Limits Overlooked
People on this site systematically overestimate the speed at which companies can deeply adopt AI & underestimate the impact of AI’s jagged abilities in limiting AI’s utility in the short run. Work will certainly start to change but companies have a...
AI Could Be the First Non‑displacing Productivity Wave
L: Productivity miracle 1.0 - autos (white) replace horses (orange) in 10 yrs; horses never recover R: Productivity miracle 2.0 - China replaces US manufacturing workers; US mfg workers down ~35% in 10 yrs Productivity miracle 3.0 - AI v. white-collar jobs;...
AI Sparks Entrepreneurial Energy: 4 Organizational Strategies
4 ways to inject new entrepreneurial energy into your organization, using AI as a catalyst. via @forbes https://t.co/3mNojgxEHQ
Pro AI Models Outperform Free Versions, Delivering Correct Answers
There is a vast difference between free models and pro models. Grok expert and ChatGPT 5.2 pro both gave the right results. I can confirm the regular ChatGPT 5.2 tells you to walk. https://t.co/8mTPUcwRpZ
Top AI Users Customize Solutions and Embrace Partnerships
What are the top 5% of successful gen AI user companies doing differently? The common denominator is that they are mastering the art & science of customizing AI to their businesses, while fostering partnerships versus go-it-alone approaches. https://t.co/xoEhkT5gvf @ZDNET
Soviet Dogs Lead 1966 Secret Voskhod Mission Against Gemini
60 YEARS AGO TODAY: The USSR launches a Voskhod spacecraft with the dogs Ugolyok and Veterok on a secret mission to prepare a response to NASA's Gemini project. FULL STORY: https://t.co/AWISaZC2RC
24 Concise Chapters Showcase Diverse Author Perspectives
Interesting format for a review article. 24 brief chapters, each offering perspective from a small subset of the 69 authors on a particular topic. https://t.co/S49x2Mr1g2
French Startup Unveils Universal Home Energy Management System
French startup launches ‘universal’ home energy management system #energysky -- via pv magazine global: https://t.co/eot5SeQ3va
