Consolidated Edison Inc (ED) Q4 2025 Earnings Call Transcript
Iridium Communications reported Q4 2025 results that met guidance, with full‑year service revenue up 3% and OIBDA reaching $495.3 million, a 5% year‑over‑year increase. Pro forma free cash flow hit $296 million, supporting a 3.3% dividend yield and a share‑repurchase program that retired 6.8 million shares. Management highlighted the upcoming launch of Iridium NTN Direct, a standards‑based narrowband IoT service, and a new ASIC for its Positioning, Navigation and Timing (PNT) offering, while announcing a shift to cash‑only incentive compensation in 2026. Guidance projects flat‑to‑2% revenue growth and OIBDA of $480‑$490 million for 2026.
Grail Inc (GRAL) Q4 2025 Earnings Call Transcript
Grail reported Q4 2025 revenue of $36.2 million, a 26% year‑over‑year rise, driven by 45,000 Gallery tests sold—a 39% volume increase. The company completed a $325 million private placement, boosting cash to roughly $850 million, and announced a strategic partnership with Samsung that...

React Native SDK 8.0.0 Is Here
Sentry has launched React Native SDK 8.0.0, its first major release since September 2025. The update introduces native‑layer app start error capture, upgrades core native dependencies, and raises minimum OS and tooling versions. Migration is straightforward via the provided guide,...
Klarna Group PLC (KLAR) Q4 2025 Earnings Call Transcript
Klarna Group reported a 28% jump in active consumers to 180 million and a 42% increase in merchants to 966,000 in Q4 2025. Gross merchandise volume hit $38.7 billion and revenue topped $1 billion, both surpassing guidance. Transaction margin dollars after provisions rose 17%...
Transforming Dynamics 365 Marketing Engagement Into Automated Business Workflows
Most firms still rely on manual follow‑up after marketing emails, causing delays and missed opportunities. Dynamics 365 Customer Insights – Journeys centralizes interaction data in Dataverse and automates lead scoring using custom triggers linked to Power Automate. By mapping email opens, clicks, form submissions, and event...
Pulse Biosciences Inc (PLSE) Q4 2025 Earnings Call Transcript
Pulse Biosciences reported its first commercial revenue of $86,000 from limited market release of the nPulse platform and Vibrance disposables. The company completed over 200 procedures across pilot programs and advanced multiple clinical studies, including FDA IDE clearance for the...
Epam Systems Inc (EPAM) Q4 2025 Earnings Call Transcript
EPAM Systems reported Q4 2025 revenue of $1.4 billion, a 12.8% year‑over‑year increase, and AI‑native revenue topped $105 million, on track to exceed $600 million in 2026. The company posted GAAP EPS of $1.98 and non‑GAAP EPS of $3.26, while free cash flow...
Host Control of Persistent Epstein–Barr Virus Infection
A multinational consortium investigated how host genetics influence persistent Epstein‑Barr virus (EBV) infection. Using large‑scale genome‑wide association studies across diverse cohorts, the team identified several host loci that modulate viral load and serostatus. Functional analyses linked these loci to immune...

Blood Test Holds Promise for Predicting when Alzheimer’s Symptoms Will Start
Researchers have developed a blood test that quantifies an abnormal form of tau protein, acting as a molecular clock to predict not only the likelihood of Alzheimer’s disease but also the timing of symptom onset. The study, published in Nature...
Onto Innovation Inc (ONTO) Q4 2025 Earnings Call Transcript
Onto Innovation reported Q3 2025 revenue of $218.2 million, surpassing the midpoint of its guidance, with a 54% gross margin and 21.1% operating margin. Advanced nodes contributed $54 million and are projected to reach $300 million for the full year, while specialty packaging...
Wayfair Inc (W) Q4 2025 Earnings Call Transcript
Wayfair reported Q4 2025 revenue up 6.9% YoY (7.8% excluding Germany), with adjusted gross margin steady at 30.3% and contribution margin improving to 15.3%. Adjusted EBITDA surged to $224 million, driving full‑year EBITDA above $743 million and free cash flow up 40%...
American Homes 4 Rent (AMH) Q4 2025 Earnings Call Transcript
American Homes 4 Rent reported a 6.2% year‑over‑year increase in core FFO per share to $0.47 and nudged its full‑year core FFO guidance to $1.87 per share. The company completed its development deliveries for the quarter, redeploying proceeds from the...

Adland’s Top Strategists on AI, Tools & the Strategic Human Advantage
South Africa’s top ad strategists warn that while AI can accelerate data collection and pattern detection, the true strategic advantage remains human deep thinking and cultural insight. Leaders such as Pepe Marais and Neo Makhele stress that only a small minority who...
Dropbox Inc (DBX) Q4 2025 Earnings Call Transcript
Dropbox posted Q3 2025 revenue of $634 million, a modest 0.7 % decline YoY, while non‑GAAP operating margin surged to 41.1 % above guidance. The company launched its self‑serve AI product Dash at $19 per user, achieving 60 % weekly active user engagement among...
PTC Therapeutics Inc (PTCT) Q4 2025 Earnings Call Transcript
PTC Therapeutics announced a definitive agreement to sell its Kepware and ThingWorx businesses to TPG for up to $725 million, shifting focus to its core CAD, PLM, ALM, and SLM platforms. The company reported 8.5% constant‑currency ARR growth to $2.446 billion and...
Travere Therapeutics Inc (TVTX) Q4 2025 Earnings Call Transcript
Vertex Pharmaceuticals reported fourth‑quarter 2025 revenue of $3.2 billion, a 10% year‑over‑year increase, and full‑year revenue of $12 billion, up 9%. The company highlighted strong growth in its cystic fibrosis (CF) franchise, with 7% global expansion and double‑digit gains in the...
Agentic AI Redefines B2B Marketing: Lean Teams, Strategic Humans
The future of agentic AI in B2B marketing is finally coming into focus. The B2B marketing org structure has to change, with fewer layers and more shared accountability across a unified data layer. The human role will shift to something...

Win $1000 Creating AI Video for Claude Code
Just for fun: AI music video contest In celebration of Claude Code’s 1 yr bday, I will give $1000 USD to the best* music video for “Ode to Claude Code” To submit: - Find the song on Spotify - Use AI to create music...
Jimmy Hoover: Can AI Give You a Seat Inside the Supreme Court?
The nonprofit project On the Docket uses artificial intelligence to generate video avatars of U.S. Supreme Court justices reading their opinions aloud, pairing AI‑created visuals with authentic archival audio. By recreating the experience of the court’s public gallery, the initiative...
Josh Aaron: The Hidden Technology Risk Law Firms Can No Longer Treat as Background Noise
Law firms are increasingly confronted with demanding security questionnaires from Fortune 500 clients, requiring verifiable endpoint protection within tight deadlines. Many firms still rely on manual or semi‑automated processes, leaving gaps in device visibility and patch compliance. This lack of...
Everlaw: Generative AI’s Growing Strategic Value for Corporate Law Departments
Everlaw and the Association of Corporate Counsel released a survey showing generative AI use in corporate law departments has more than doubled, reaching 52% of U.S. respondents. The share of firms merely planning AI projects fell to 14%, while outright...
Now We Know Why Tesla Killed Autopilot
Tesla has discontinued the Autopilot name and removed Autosteer from new vehicles after a California DMV compliance order. The DMV warned that misleading marketing could trigger a 30‑day suspension of Tesla's dealer and manufacturer licenses. To avoid the penalty, Tesla...

Booking CEO Touts Ties With Independent Hotels as Agentic AI and Airbnb Seek Gains
Booking Holdings CEO Glenn Fogel emphasized the platform’s deep ties with independent hotels, which supply the bulk of its room nights, as the company confronts rising pressure from AI‑driven travel agents and Airbnb’s expansion into the boutique‑hotel segment. He announced...
Gov.UK: Update on the Serious Fraud Office’s E-Discovery Review
The UK Serious Fraud Office (SFO) has completed its e‑discovery review of historic fraud convictions that relied on the legacy Autonomy system. Out of 66 identified cases, only three remain under final review, and the SFO reports no material that...
First SAFE Closing Saves Founder Money, Attorney Time
We are running out 1st SAFE closing for a startup through the 9to5 Docs platform. Founder saves $$$ and Attorney saves time. Win-win.
Genentech’s Fenebrutinib Yields Positive Results in Phase III MS Trial
Genentech’s oral BTK inhibitor fenebrutinib met its primary endpoint in the Phase III FENtrepid trial for primary progressive multiple sclerosis, showing non‑inferiority to Ocrevus and a 12% risk reduction in confirmed disability progression. The drug also delivered a 26% lower risk...
[Therapeutics] Adaptive Deep Brain Stimulation in Parkinson's Disease
Adaptive deep brain stimulation (aDBS) introduces real‑time modulation of stimulation amplitude by tracking subthalamic beta activity, shifting Parkinson's therapy from fixed to physiomarker‑guided. Clinical trials report superior motor improvement, reduced stimulation‑related side effects, and markedly lower energy consumption compared with...

IRS CIO Says Agency Lost 40% of Tech Workers Last Year
The Internal Revenue Service’s Chief Information Officer disclosed that the agency shed roughly 40% of its IT workforce and almost 80% of its technology leadership last year, marking the deepest attrition in two decades. The cuts stemmed from voluntary separations,...
Chief AI Officer Alex Deer Speaks at India AI Summit
Our Chief AI Officer @alexanddeer will take the stage at the India AI Impact Summit. Date: Thursday, February 19 Time: 1:53pm IST // 12:23am PST Watch the livestream here: https://www.youtube.com/live/WgW7cC-kHgY

Wyndham Takes $160 Million Hit After European Franchisee Files for Insolvency
Wyndham Hotels disclosed a $160 million charge after its largest European franchisee, Revo Hospitality Group, entered self‑administration in January. The charge covers uncollectible receivables, asset impairments and a write‑down of the Vienna House trademark acquired in 2022. Despite the setback, the...

AI Won’t Kill SaaS; Governance Still Essential
Narratives can crush multiples faster than fundamentals change. Markets are pricing “software is dead” as if AI will commoditize SaaS overnight. But enterprises still need governance, permissioning, audit trails, compliance, uptime, and data orchestration. AI may change workflows, but it doesn’t...
Researchers Develop RNA-Activated Implant to Stimulate Nerve Regrowth After Spinal Cord Injury
Researchers at RCSI have created a 3‑D biomaterial implant that releases PTEN‑targeting siRNA to injured spinal cord neurons, reactivating growth pathways. The scaffold replicates spinal cord mechanical properties and delivers RNA particles directly to the lesion site, silencing the PTEN...

Etsy Sells Secondhand Clothing Marketplace Depop to eBay for $1.2B
Etsy announced it will sell its second‑hand fashion app Depop to eBay for $1.2 billion in cash. Depop, which posted roughly $1 billion in gross merchandise volume and 7 million active buyers in 2025, was acquired by Etsy in 2021 for $1.62 billion. The...
Mass Production Technology Developed for Ultra-High Color Purity Perovskite Emitters
Professor Tae‑Woo Lee’s team has unveiled a cold‑injection synthesis that mass‑produces perovskite nanocrystals with ultra‑high color purity at ambient temperature, eliminating the need for high‑temperature, vacuum or specialized gas facilities. The process achieves near‑100 % photoluminescence quantum yield and an external...

Solera Health Launches Behavioral Health Network with Calm and Lyra
Solera Health announced a new behavioral health network that links its HALO platform with Calm Health and Lyra Health. The service directs members to self‑guided apps or therapist‑led care based on their reported needs, expanding support beyond anxiety and depression...
Top HHS Officials Tout TEFCA Data-Sharing Framework As Central To MAHA
Top officials at the Department of Health and Human Services highlighted the Trusted Exchange Framework and Common Agreement (TEFCA) as a cornerstone of the "Make America Healthy Again" (MAHA) initiative. TEFCA, mandated by the 2016 bipartisan law, seeks to create...

UrbanToronto Webinar: State of Construction in the GTA
UrbanToronto is kicking off a free 2026 webinar series focused on the Greater Toronto Area construction market, with the first session scheduled for February 25. The inaugural webinar, titled "Exploring the State of Construction in the Toronto Region," will feature...

Geopolitical Analysis: U.S. Space Strategy in Africa Facing Chinese Competition
The Atlantic Council’s 2026 strategic analysis warns that the United States must overhaul its commercial partnership model with African nations to counter China’s accelerating foothold in the continent’s space economy. China’s 2025 handover of a telemetry, tracking and command station...
US Vaccine Policy Shift Boosts MRNA Stock Appeal
Macro: US vaccine-policy swing heightens regulatory risk; FDA will review Moderna’s flu shot. Key: public dispute, amended filing; decision by Aug 5. Risk: political oversight. Trade: Buy MRNA. — Viktor Kopylov, PhD, CFA More insights: t.me/si14Kopylov
Amazon Teams with OpenAI for Custom Shopping AI
🚨 My new exclusive at @ReadTheAisle Amazon has discussed w/ OpenAI working on custom shopping-related AI tied to Rufus, after using its own models and then Anthropic’s, according to sources briefed. The focus goes beyond Rufus’ main use of product Q&A https://t.co/60Z6WBfyvh

Tech Firms Must Remove ‘Revenge Porn’ in 48 Hours or Risk Being Blocked, Says Starmer
The UK government will amend the Crime and Policing Bill to require tech platforms to delete non‑consensual intimate images, including AI‑generated deepfakes, within 48 hours of notification. Enforcement will be handed to Ofcom, which can levy fines up to 10%...
High‑Voltage DC Cuts AI Data Center Costs
High-voltage DC design targets AI data center costs #energysky -- via pv magazine global: https://t.co/xe594PCmhP
GitHub PR Navigation Speed Boost Improves Daily Workflow
GitHub issue/PR navigation is significantly faster recently. Large PRs also render so much better [on Safari, especially]. It is noticeably improving my day since I navigate between them with high frequency. Thanks to whoever made this happen. ❤️

REMAX Names New President; Tech Exec Joins Offerpad Board
REMAX promoted Chris Lim, who joined a year ago as chief growth officer, to president while keeping his growth responsibilities. Lim, formerly president of Christie’s International Real Estate, will now oversee the global network, emphasizing international expansion and affiliate services....
Replit on Databricks Reveals Why Software Stocks Slump
When start vibecoding your business apps with Replit directly on your Databricks you get why the market is so bearish on software stocks.
Vantor Precision3D Surface & Terrain Models Now on Satellite Data Explorer
Digital Surface and Terrain Models from Vantor’s Precision3D Product Line Added to Satellite Data Explorer https://t.co/wwaePneP9X 4 min read Digital Surface and Terrain Models from Vantor’s Precision3D Product Line Added to Satellite Data Explorer N… https://t.co/GyiCqb3Lrp
Federal Circuit Clarifies Patent-Risk Boundaries in Government-Sponsored R&D
The Federal Circuit affirmed that AeroVironment’s UAV development under SBIR and STTR contracts is protected by 28 U.S.C. § 1498, barring patent‑infringement suits against the contractor. The court held the work was performed for the United States with government authorization, shifting any remedy...
NASA Releases Multispectral Satellitegic Data via CSDA Program
NASA’s Commercial Satellite Data Acquisition Program Releases Archived and Tasked Multispectral Data from Satellogic https://t.co/5hA84hrb1m CSDA Menu CSDA Commercial Data Commercial Datasets Commercial Satellite Data Explorer Satellite Data Eval… https://t.co/QN5MKM4S4J
Michigan Bills Would Regulate Automatic License Plate Readers
Michigan lawmakers have introduced a bipartisan two‑bill package to regulate automatic license plate readers (ALPRs) used by law‑enforcement and private firms. The proposals would restrict data collection, storage, and sharing, limit retention to 14 days, and require quarterly public reports...

GAO: Millions of People Can’t Understand Life-or-Death Weather Alerts
The GAO report warns that roughly 26 million Americans with limited English proficiency struggle to comprehend life‑or‑death weather alerts. Outdated alert infrastructure, insufficient staffing, and slow translation processes prevent timely multilingual warnings. GAO recommends modernizing the National Weather Service’s system with...