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Announcing The Forrester Wave™: AI Infrastructure Solutions, Q4 2025
NewsDec 16, 2025

Announcing The Forrester Wave™: AI Infrastructure Solutions, Q4 2025

The episode highlights the shift in AI infrastructure from experimental pilots to production‑scale workloads, emphasizing the need for integrated solutions that balance compute, networking, storage, and operations. It introduces the Forrester Wave™: AI Infrastructure Solutions, Q4 2025, which evaluates vendors on...

By Forrester Generative AI
Who Invented What? BIO IP Panel Tackles Joint Inventorship
NewsDec 16, 2025

Who Invented What? BIO IP Panel Tackles Joint Inventorship

The BIO IP panel highlighted that joint inventorship is now the norm in biotech, replacing the lone‑inventor myth. It outlined the legal elements—conception, collaboration, corroboration—and illustrated them with real and hypothetical cases, including AI‑driven research. Panelists warned that mis‑attributing inventors...

By Bio.News
AI Agents Wear Multiple Masks—Ensure Ethics and Transparency
SocialDec 16, 2025

AI Agents Wear Multiple Masks—Ensure Ethics and Transparency

You compartmentalize your emotions, why not your AI?   Emotionally partitioned AI agents are single AI systems that switch between different personas for regulators, customers, and internal teams, adjusting tone, priorities, and emotional style to match each audience. This makes interactions smoother...

By Robert Scoble
ChatGPT Images Now Offers Faster, Precise Editing
SocialDec 16, 2025

ChatGPT Images Now Offers Faster, Precise Editing

The new ChatGPT Images is here. More precise edits, stronger instruction following, and up to 4x faster generation, while preserving details like lighting, composition, and likeness across edits. From quick fixes to full reimaginings, it’s easier to get exactly what you have...

By Nick Turley
Google Tests an Email-Based Productivity Assistant
NewsDec 16, 2025

Google Tests an Email-Based Productivity Assistant

Google has introduced CC, an experimental email‑based productivity assistant powered by Gemini, through its Google Labs program. The service delivers a daily “Your Day Ahead” email that aggregates tasks, calendar events, and key updates from Gmail, Drive, and Calendar. Users...

By TechCrunch Apps
Get Real-Time Founder Advice Before Decisions Harden
SocialDec 16, 2025

Get Real-Time Founder Advice Before Decisions Harden

Most advice fails for a simple reason. It shows up too late. By the time founders ask for help, the decision has already hardened. Positions are entrenched. Narratives are locked. The cost of being wrong has gone up. Uncapped Notes Live is designed...

By Hiten Shah
SAM Audio Isolates Any Sound From Mixtures via Prompts
SocialDec 16, 2025

SAM Audio Isolates Any Sound From Mixtures via Prompts

🔉 Introducing SAM Audio, the first unified model that isolates any sound from complex audio mixtures using text, visual, or span prompts. We’re sharing SAM Audio with the community, along with a perception encoder model, benchmarks and research papers, to empower...

By Meta
Amazon Says Russian Hackers Behind Major Cyber Campaign to Target Western Energy Sector
NewsDec 16, 2025

Amazon Says Russian Hackers Behind Major Cyber Campaign to Target Western Energy Sector

Amazon’s security team has identified a sustained Russian GRU‑linked cyber campaign that has been compromising misconfigured edge devices in Western critical infrastructure, especially the energy sector, since 2021. The attackers, including the group known as Curly COMrades, exploit virtualization features such...

By TechRadar
Scale Revenue Only When Customer Success Is Predictable
SocialDec 16, 2025

Scale Revenue Only When Customer Success Is Predictable

If you’re looking for your moment to scale, be careful not to confuse consistent revenue creation with consistent customer success creation. They’re not the same thing. You can grow revenue fast without seeing customer success — especially in the early...

By Mark Roberge
AI Agents Becoming Full‑Fledged Employees, Not Just Tools
SocialDec 16, 2025

AI Agents Becoming Full‑Fledged Employees, Not Just Tools

Microsoft’s AI agents are getting… Workday HR profiles. Not metaphorically. Not conceptually. Actual HR profiles... alongside company email addresses, Teams access, and a seat next to human coworkers in the org chart. It’s the clearest signal yet that enterprises love...

By Cassie Kozyrkov
Bridging the Divide: How Sanket Sable Is Architecting the Future of Privacy-First AI in Advertising
NewsDec 16, 2025

Bridging the Divide: How Sanket Sable Is Architecting the Future of Privacy-First AI in Advertising

Sanket Sable, a senior technical solutions consultant at Google, has pioneered the "Shapeshifters" project, which integrates Gemini large language models with ad platforms to enable intent‑driven, hyper‑personalized advertising at scale. He also designed a DMA‑compliant measurement framework for Ads Data...

By AI Time Journal
Fenebrutinib (GDC-0853)
BlogDec 16, 2025

Fenebrutinib (GDC-0853)

Fenebrutinib (GDC‑0853) is an oral, reversible Bruton’s tyrosine kinase (BTK) inhibitor that entered Phase 3 trials for multiple sclerosis in a November 2025 press release. The drug was discovered through ATP‑site‑directed compound library screening and subsequently optimized by Roche and Genentech. Its...

By Drug Hunter
UltraMarathonRT: When Your Reverse Transcription Must Go Long
BlogDec 16, 2025

UltraMarathonRT: When Your Reverse Transcription Must Go Long

RNAConnect has launched a new kit for Oxford Nanopore direct‑RNA sequencing that uses UltraMarathonRT, a group II intron‑derived reverse transcriptase. Unlike traditional AMV or M‑MLV enzymes, UltraMarathonRT is highly processive, can copy RNA longer than 30 kb, and works at a gentle...

By Omics! Omics!
Weight Decay Softly Prunes Noisy Features, Not Just Simplicity
SocialDec 16, 2025

Weight Decay Softly Prunes Noisy Features, Not Just Simplicity

Weight decay is usually presented as “encouraging simpler solutions”, but I tend to think that the real benefit is the soft pruning of noisy / unhelpful features. Without decay, a weight can random-walk to a large value even if the...

By John Carmack
Build SaaStr University 2.0 Yourself with Replit
SocialDec 16, 2025

Build SaaStr University 2.0 Yourself with Replit

In early 2026, it will be time to rebuild SaaStr University 20,000 founders have used it to learn GTM, it’s free courses and it’s great. But it’s also time to rebuild it. So the question is: - Use existing platform - Pick a...

By Jason Lemkin
VIDO – Five Ways Our Research Strengthened Animal Health in 2025
NewsDec 16, 2025

VIDO – Five Ways Our Research Strengthened Animal Health in 2025

In 2025 the University of Saskatchewan’s Vaccine and Infectious Disease Organization (VIDO) tackled five critical animal‑health challenges, from a first‑record H5N1 outbreak in dairy cattle to a world‑first chlamydia vaccine for endangered koalas. Researchers demonstrated natural immunity in infected cows,...

By BIOTECanada
Pipeline Stalls when Good Ideas Are Out of Order
SocialDec 16, 2025

Pipeline Stalls when Good Ideas Are Out of Order

Most pipeline issues don’t come from bad ideas. They come from stacking good ideas in the wrong order. What we see when teams try to “keep momentum”: • More top-of-funnel before fixing demo conversion • New campaigns while stalled deals...

By devbasu
Notion's 20x Revenue Surge Yields Only 1.2x Valuation
SocialDec 16, 2025

Notion's 20x Revenue Surge Yields Only 1.2x Valuation

Notion grows from $30m ARR ($10b series C) to $600m ARR today: Now considering a $12b tender offer. BUT Only 1.2x valuation increase despite 20x revenue increase? yeah tender may be common shares generally valued less than preferred (Series C)...

By Nathan Latka
Hacking Group Says It’s Extorting Pornhub After Stealing Users’ Viewing Data
NewsDec 16, 2025

Hacking Group Says It’s Extorting Pornhub After Stealing Users’ Viewing Data

Scattered Lapsus$ Hunters, linked to the ShinyHunters gang, announced an extortion attempt against Pornhub after stealing personal data of premium members through a breach at analytics provider Mixpanel. The stolen information includes email addresses, location, and detailed viewing activity such...

By TechCrunch (Cybersecurity)
Novel Writing Techniques Elevate B2B Content Strategy
SocialDec 16, 2025

Novel Writing Techniques Elevate B2B Content Strategy

In 2023 and 2024, I wrote a fictional novel that never got published. But the process taught me so much (I mean so much) about storytelling—especially story setup, drama, suspense and more. I’ve since infused those lessons into B2B marketing,...

By Pam Didner
UPS Buys Hundreds of Robots to Unload Trucks in Automation Push
NewsDec 16, 2025

UPS Buys Hundreds of Robots to Unload Trucks in Automation Push

United Parcel Service is spending $120 million to acquire 400 Pickle Robot units that can unload trucks in about two hours each. The purchase is part of UPS’s broader $9 billion automation program aimed at cutting labor costs and boosting margins. Pickle’s...

By Tech Xplore Robotics
Overnight Successes Usually Take Two Years to Start
SocialDec 16, 2025

Overnight Successes Usually Take Two Years to Start

Most overnight success stories were founded at least 2 years before you’d ever heard of them Often, 2 years before they even had a paying customer

By Jason Lemkin
Avoid These Founder Exit Pitfalls with Goldman Sachs
SocialDec 16, 2025

Avoid These Founder Exit Pitfalls with Goldman Sachs

In our latest episode of Vista Point Advisors ' podcast, The Path to Exit, I sat down with Sarah Letourneau from Goldman Sachs to talk about the most common pitfalls we see founders encounter when preparing for an exit. Listen...

By Michael Lyon
Jailbreaking AGI: Pliny the Liberator & John V on AI Red Teaming, BT6, and the Future of AI Security
PodcastDec 16, 20250 min

Jailbreaking AGI: Pliny the Liberator & John V on AI Red Teaming, BT6, and the Future of AI Security

In this episode, Pliny the Liberator and John V discuss their radical approach to AI red‑teaming, emphasizing universal jailbreaks—skeleton‑key prompts that bypass guardrails across modalities—and the shortcomings of RLHF‑based safety as mere security theater. They detail hard vs. soft jailbreak...

By Latent Space
Without Clear Narrative, Product Improvements Erode Customer Trust
SocialDec 16, 2025

Without Clear Narrative, Product Improvements Erode Customer Trust

Founders underestimate how much narrative work the product needs. Shipping creates change. Marketing explains change. When explanation lags, customers experience motion as noise. Confusion quietly erodes trust even when the product improves.

By Hiten Shah
Agentic AI Turns Workflow Bottlenecks Into Speed
SocialDec 16, 2025

Agentic AI Turns Workflow Bottlenecks Into Speed

Complex deals move at the speed of their slowest workflow. One approval pauses another. One review delays the next step. Momentum fades quietly. Agentic AI introduces a new execution tempo when each step becomes computationally accessible. Velocity shifts from constraint...

By Geoffrey Moore
The $7,500 Migration Fee That Just Cost a Vendor $80,000 ARR.  Really, $240,000.
BlogDec 16, 2025

The $7,500 Migration Fee That Just Cost a Vendor $80,000 ARR. Really, $240,000.

An $80,000 ARR SaaS deal was lost when the vendor imposed a $7,500 migration fee, pushing the contract into the following year. The author argues that such fees create friction, extending ROI timelines and giving incumbents a chance to retain...

By SaaStr
Own Your Investment
SocialDec 16, 2025

Own Your Investment

A man asked me to build his personal brand for "a small fee upfront, with more money based on the performance." But first, let me tell you about The Gym Guy. A man walks into a high-end gym and says:...

By Krista Mollion
Design.com: Launch a Professional Brand Across Digital and Print in Minutes, Not Months
PodcastDec 16, 2025

Design.com: Launch a Professional Brand Across Digital and Print in Minutes, Not Months

Design.com launches an AI‑powered, all‑in‑one branding platform that lets founders and marketers create logos, websites, social graphics, and print collateral in minutes instead of months. The service blends generative AI with a customizable editor, delivering instant concepts for names, domains,...

By Martech Zone Interviews
Delay VP Hires Until You Hit Double‑digit ARR
SocialDec 16, 2025

Delay VP Hires Until You Hit Double‑digit ARR

Hiring a VP of anything before double-digit ARR is a horrible move. I am a pathologically lean startup builder … And I fully believe that $1-10M ARR should be the founder(s) only. VP of Sales only at $10M+. Once you have...

By Adam Robinson
Fix Activation Now or Sink Your Business Economics
SocialDec 16, 2025

Fix Activation Now or Sink Your Business Economics

The cost of bad activation is WAY more than most founders realize. It’s easy to write off a few drop-offs as a "UX issue." In reality, friction compounds across your entire business model. 1. Higher Acquisition Costs If your signup...

By Wes Bush
Creating Psychological Safety in the AI Era
NewsDec 16, 2025

Creating Psychological Safety in the AI Era

Enterprise AI adoption hinges on psychological safety, enabling staff to experiment without fear of reprisal. A MIT Technology Review Insights survey of 500 leaders shows 83% believe safety boosts AI project success, yet only 39% rate their organizations as very...

By MIT Technology Review
When to Delegate Core SaaS Skills and Boost Retention
SocialDec 16, 2025

When to Delegate Core SaaS Skills and Boost Retention

When should you start delegating the Four Core SaaS skills? Can great founders succeed with any product idea? What's a good freemium retention rate? I answer these listener questions (with a little help from Ruben Gamez ) and more in...

By Rob Walling
SEO Is Foundation; AI Optimization Demands Extra Effort
SocialDec 16, 2025

SEO Is Foundation; AI Optimization Demands Extra Effort

Solid #SEO is the basis of GEO, or AIO, or whatever one wants to call it. But optimizing for AI requires a bit more as well.

By Tom Pick
WORK-SELF Launches the World’s First Identity-Led Career Operating System Powered by Agentic AI
NewsDec 16, 2025

WORK-SELF Launches the World’s First Identity-Led Career Operating System Powered by Agentic AI

WORK‑SELF unveiled the world’s first identity‑led Career Operating System, powered by agentic AI, to serve as a persistent career co‑pilot for individuals and coaches. Unlike traditional job‑matching tools, the platform begins with a user’s identity, values, energy patterns, and strengths,...

By MarTech Series
Create Your Own Custom Board AI Today
SocialDec 16, 2025

Create Your Own Custom Board AI Today

Build your own @boardyai.

By Robert Scoble
Generative Engine Optimization Is Just B2B Snake Oil
SocialDec 16, 2025

Generative Engine Optimization Is Just B2B Snake Oil

Beware the "Generative Engine Optimization" Snake Oil - B2B Marketing Blog | Webbiquity - https://t.co/TVZSwDd1lo

By Tom Pick
How AI Can Lead To A More Valuable And Creative Advertising Industry
NewsDec 16, 2025

How AI Can Lead To A More Valuable And Creative Advertising Industry

Artificial intelligence is reshaping advertising by slashing production costs, expanding access, and automating asset selection, while reinforcing creativity as the sector's core moat. McKinsey estimates generative AI could unlock $2.6‑4.4 trillion across industries, and Gartner predicts agentic AI will resolve 80%...

By MarTech Series
Benchmark Humans Against the Best Alternative, Not Averages
SocialDec 16, 2025

Benchmark Humans Against the Best Alternative, Not Averages

You should measure human capability on a task not in terms of "average human" or "random human", but in terms of your best alternative (to AI) if you were to hire a human to solve the task. Which isn't average...

By François Chollet
Clarity Is the Ultimate Leverage for Inevitable Execution
SocialDec 16, 2025

Clarity Is the Ultimate Leverage for Inevitable Execution

Founders often search for leverage in tools, hires, or tactics. The deepest leverage is clarity. When people know exactly what matters and why, execution stops feeling heroic and starts feeling inevitable.

By Hiten Shah
India’s Digantara Raises $50M for Space-Based Missile Defense Tech
NewsDec 16, 2025

India’s Digantara Raises $50M for Space-Based Missile Defense Tech

Digantara, an Indian space‑surveillance startup, secured a $50 million Series B round to broaden its portfolio from debris tracking to missile detection. The funding, led by new investors 360 ONE Asset and SBI Investment of Japan, brings total capital to $64.5 million and will...

By TechCrunch - Space
Securely Share Revenue Metrics with Anyone via Link
SocialDec 16, 2025

Securely Share Revenue Metrics with Anyone via Link

New @metricablecom feature: Share your revenue metrics with anyone you'd like via a secure link or by inviting them as a viewer. What features should we add next? https://t.co/0NPvWj5RkG

By Andrew Gazdecki
AI's Potential to Create Original Scientific Discoveries
SocialDec 16, 2025

AI's Potential to Create Original Scientific Discoveries

new on @airstreetpress: can ai generate new science? link below https://t.co/5egWvv3OPd

By Nathan Benaich
AI Platform Launches Automated Web Monitoring for Businesses
SocialDec 16, 2025

AI Platform Launches Automated Web Monitoring for Businesses

Gowatch (@gowatchai) is the AI monitoring platform for businesses. Easily set up AI agents that search and monitor the web for your competitors, customers, investments, and more. Congrats on the launch, @charliejmaki, @coreyaanderson, and @14cam31! https://t.co/ZqQwiReJW5 https://t.co/v3d1YYqtn4

By YCombinator
How Companies React to Mistakes Reveals Their Priorities
SocialDec 16, 2025

How Companies React to Mistakes Reveals Their Priorities

You can learn a lot about a company by watching what happens after a mistake. Do people rush to explain it away, or do they slow down to understand it. One path protects egos. The other protects the future.

By Hiten Shah
Founder Focus: Iterate Relentlessly Until Traction Arrives
SocialDec 16, 2025

Founder Focus: Iterate Relentlessly Until Traction Arrives

Founders need “horse blinders.” Campfire iterated for months before hitting real traction — despite early customers. Big lesson from John Glasgow in Episode 222 of The SaaS CFO Podcast. Watch 👉 https://t.co/TSr37V0Z82 https://t.co/ldyqGESF7e

By Ben Murray
Customer Care Pays: The Numbers Prove It
SocialDec 16, 2025

Customer Care Pays: The Numbers Prove It

The numbers behind the value of treating your customers well.

By Tom Pick
Open‑source Chatterbox Turbo Beats TTS Leaders on Latency
SocialDec 16, 2025

Open‑source Chatterbox Turbo Beats TTS Leaders on Latency

If you’re building voice agents, latency matters more than anything. For years, proprietary TTS dominated benchmarks. That’s changing. @ResembleAI’s Chatterbox Turbo is reshaping benchmarks: → Open-source → Crushes ElevenLabs & Cartesia on quality → Far lower latency 🧵↓ https://t.co/7xvyL9q65M

By Data Chaz
AI Search Cuts Clicks, B2B Still Relies on Clicks
SocialDec 16, 2025

AI Search Cuts Clicks, B2B Still Relies on Clicks

As AI search reduces clicks, publishers are exploring licensing and revenue sharing. Here’s what the shift means for #SEO and content strategy. https://t.co/kNgg4TbkpD via @MattGSouthern, @sejournal But is "the click economy over"? Really? Not in #B2B.

By Tom Pick