
TMTB Weekly
The week was dominated by AI headlines, highlighted by Anthropic announcing a $30 B annual recurring revenue run rate and sealing a joint infrastructure deal with Google and AMD. Meta responded with its Muse Spark model, positioning the company alongside other state‑of‑the‑art systems. Meanwhile, software stocks endured their steepest three‑day decline relative to semiconductors, even as the TMT sector posted its strongest week on record. Geopolitical risk resurfaced as U.S. forces moved to block the Strait of Hormuz, keeping oil prices elevated.
Put Top Customers and Engineers in a Chat
Protip: Create an X group chat with your best and most demanding customers. Put your engineering leads in said group chat. Respond and ship quickly. Face the music. We have one going for @v0. DM if you want to be a...
Show HN: BoringBar – a Taskbar-Style Dock Replacement for macOS
Show HN introduces boringBar, a taskbar‑style dock replacement for macOS Sonoma and later. The app reorganizes windows by desktop, offers instant thumbnails, a searchable launcher, and one‑click desktop switching, while optionally hiding the native Dock. Users can trial the full...
SYNAOS Scales NA Operations as Demand for Interoperable Intralogistics Accelerates
SYNAOS, a provider of intralogistics orchestration software, announced a major expansion of its North American operations to meet rising demand for vendor‑agnostic automation. The move follows its collaboration with Rockwell Automation and OTTO Motors to advance the VDA 5050 standard for mixed‑fleet...

YouTube Adds More AI
YouTube has extended its conversational AI assistant from phones and browsers to smart TVs, gaming consoles, and streaming devices. The feature, accessed via an on‑screen “Ask” button or remote microphone, lets viewers pose questions about a video without stopping playback....

AI’s Dumb Genius Problem
The piece contends that AI’s next breakthrough lies not in bigger language models but in a missing “context engine” that links models to real‑world outcomes. It compares current AI use to brilliant minds working without a briefing, and cites Google’s...

User Doubts OneKeyCash After Missing Payment Option
Alright, is OneKeyCash a complete scam? I've booked 8 properties for an upcoming trip and not once have I ever had the opportunity to select OneKeyCash as a payment option. @vrbo @expedia @hotelsdotcom
Reddit Demands Authenticity, Not Spammy Lead Funnels
Reddit is not your free billboard. It's not a marketing channel where you dump your landing page, cross your fingers, and wait for conversions. It's one of the last places on the internet where strangers will give you brutally honest feedback if...

Grab MSI’s RTX 5080 Gaming Laptop for Just over $2,000 — Offers Fast 240 Hz QHD+ Display, Dual Storage Slots,...
MSI’s Vector 16 HX AI gaming laptop now retails for $2,099 on Newegg, making it one of the cheapest machines equipped with Nvidia’s RTX 5080 GPU. The 16‑inch QHD+ panel runs at a rapid 240 Hz, while the Intel Core Ultra 9 275HX delivers up to 5.4 GHz...
New Frontier Models Democratize AI for Everyone
We love the best frontier models but it’s worth noting there are a lot of new ones and they can also be good and useful too, especially when it comes to bringing the capabilities to more people I think about the...

Welcome to Agents Week
Cloudflare launched "Agents Week" to unveil a new infrastructure built for AI‑driven agents, which require a one‑to‑one compute model rather than the traditional many‑to‑one approach. The company highlights that scaling agents for millions of knowledge workers would demand 500 k–1 M server...

Meta AI Climbs to #3, Trailing only ChatGPT
Meta AI is currently ranked #3 on the US App Store’s Top Downloaded chart — behind ChatGPT but ahead of Claude and Gemini.
Free Certifications to Jumpstart Your Tech Career
Free certifications that can help you break into tech: 🎓 Google IT Support Certificate — Coursera 🎓 AWS Cloud Practitioner — free prep on YouTube 🎓 CompTIA Linux+ — great for SRE path 🎓 TryHackMe — free tier available No excuses. No gatekeeping. 🖤💻 Save this.

Expert Witness Credibility Is Destroyed by AI Opinions
The article warns that using generative AI to draft expert‑witness opinions jeopardizes a clinician’s credibility and can trigger Daubert challenges, because AI lacks licensure and accountability. It distinguishes between AI as a production tool—prohibited—and AI as a training aid that...
Immune Cells in the Nose Slow Influenza Virus, Study Finds
A University of Gothenburg study reveals that CD4 memory T cells linger in the nasal lining and can quickly reactivate when influenza re‑enters the body, curbing viral replication. In mouse models these resident cells lowered viral loads and limited tissue...

Meta Spent $88 Billion on a Brand No One Asked For
Meta poured roughly $88 billion into its seven‑year Metaverse push, yet the platform never attracted more than about 900 daily active users. The effort failed because it tried to invent a new category without a clear consumer need, delivered a subpar...

Exhausted Yet Relieved, Fans Crave Faster Moon Missions
Anyone else feeling the duality of absolute exhaustion and relief that Artemis 2 is over, and also a sadness in the absence of such an incredible mission to continue captivating the world? I hope @rookisaacman’s plan to launch SLS every...

AI Sparks a Meaning Crisis, Not a Labor Crisis
A bunch of people have written me back saying this was the best newsletter I have ever sent (flattering) ... so here it is for those who don't subscribe: AI Is Not a Labor Crisis. It Is a Meaning Crisis.

Defending Europe’s Financial Sector in the Age of AI‑Accelerated Cyber Threats
The IBM X‑Force Threat Intelligence Index 2026 shows Europe as the third‑most attacked region, responsible for 25% of global cyber incidents, with the financial sector bearing 35% of those attacks. Credential theft and exploitation of public‑facing applications each account for 40%...
Advanced Cardiac MRI Identifies Early Signs of Transthyretin Amyloidosis
Advanced cardiac magnetic resonance (CMR) imaging can pinpoint early, low‑burden transthyretin cardiac amyloidosis (ATTR‑CA) by revealing a basal‑predominant late gadolinium enhancement pattern. The study of 83 patients showed that quantitative tissue markers such as extracellular volume (ECV) and native T1...

The Guardian View on AI Politics: US Datacentre Protests Are a Warning to Big Tech | Editorial
The United States is witnessing a surge in AI datacenter construction, with Amazon, Microsoft and others committing roughly $710 bn this year. Grassroots protests—from MAGA‑aligned voters in Texas to liberal teachers in California—are demanding environmental safeguards and community protections. The backlash...
Untitled
On April 6, 2026, NASA’s Artemis II mission performed a historic lunar flyby, the first since Apollo 17 in 1972. The Orion spacecraft rounded the Moon’s far side, reaching a peak distance of roughly 407,000 km—making it the farthest humans have traveled from Earth...
LLM Memory Mirrors Human Limits: No Free Lunch
This is a really nice overview post on LLM memory. Nothing is earth-shattering, but it's all laid out well. And the author highlights how there's "no free lunch" and how context windows might not save us. @yishan is spot on in...

Secure Your Spot in AI-Driven Music Industry
"If you don't claim a seat at the dinner table, you're liable to wind up on the menu." I spoke to Michael Nash, Chief Digital Officer & EVP of @universalmusicgroup and @kakuls, CEO of @splice at HumanX, the AI conference in...

The Attack Your Security Strategy Wasn’t Designed to Spot
A new class of attack targets Microsoft 365 tenant configurations, letting threat actors manipulate identities, encrypt data and extort firms without deploying malware. Microsoft reported 176,000 configuration‑tampering incidents in May 2024 and 45% of large enterprises suffered a misconfiguration‑related breach in the...
Neuroscientist's AI-Powered Startup Aims To Transform Human Cognition With Perfect, Infinite Memory
Former Harvard Medical School professor and neuroscientist Amir Kreiman, together with co‑founder Spandan Madan, launched Engramme, an AI startup that claims to give humans perfect, infinite memory by linking a personal "memorome" to large memory models. The platform promises automatic...

How to Build a Custom GPT That Doesn't Suck
A recent Substack post shows that while 68% of U.S. small businesses now use AI, 80% of that usage is limited to generic chat, leading to costly hallucinations. The author illustrates the problem with a benefits‑administration solo‑entrepreneur whose poorly built...
Pasqal and True Nexus Team Up to Model Food Proteins with Quantum Computing
Pasqal and True Nexus have launched a strategic partnership to apply neutral‑atom quantum computing to food‑protein modeling. The joint effort will create the first fully vectorized, dynamic 3D model of protein gelation, a breakthrough that could shift alternative‑protein development from...
Targeted Microbubble Therapy Cuts Kidney Damage in Rat Model of Chemotherapy‑Induced AKI
Researchers led by Si, Mo and Zhao demonstrated that E‑selectin‑targeted microbubbles combined with ultrasound dramatically improve methylprednisolone’s renoprotective effect in rats with cisplatin‑induced acute kidney injury, cutting serum creatinine and preserving tubular cells. The pre‑clinical breakthrough points to a new...

Oracle AI World NYC 2026 - the Halftime Recap with Rebecca Wettemann
In this brief halftime recap from Oracle AI World NYC 2026, host John Reed chats with analyst Rebecca Wettemann about Oracle's enterprise AI strategy. She highlights Oracle's strength in unifying data across its database, OCI, and Fusion applications, which enables...
CDP Market Projected to Top $9.7 B by 2026, Fueling Sales Ops Innovation
Markets & Markets estimates the global customer data platform (CDP) market will grow from roughly $9.7 billion in 2023 to a substantially larger size by 2026. The forecast underscores how unified first‑party data is becoming a cornerstone for sales, revenue operations,...
Re: The Power of the Markets: The Scandal that Keeps on Taking
A letter to the BMJ criticizes the pharmaceutical industry’s reliance on experimental trials that deny patients post‑trial access to new drugs. It argues that powerful, profit‑driven groups manipulate regulations, limiting transparency and compromising the NHS’s ability to provide affordable treatments....
Ola Electric’s Stock Jumps Over 90% on Cheaper Model and Battery Push
Ola Electric’s shares surged from ₹21.21 to ₹40.88 after the company announced a 30% price cut on a flagship scooter and a renewed focus on battery production. The rally lifts the firm’s market value to roughly $1.9 billion, but analysts warn...

The Perfect Storm in Energy Infrastructure: High-Density Hydro, Cost Deflation, and Geopolitical Security
The energy transition is now driven by security concerns as grids strain under intermittent renewables, making long‑duration energy storage (LDES) the prime source of infrastructure alpha. High‑Density Hydro, pioneered by UK‑based RheEnergise, uses a 2.5‑times denser R‑19 fluid to slash...
Reddit AI Visibility Webinar Claims 2,000% Search Lift and Six‑Figure Deals
Search Engine Journal will host a May 5 webinar that outlines a five‑stage Reddit community framework promising up to a 2,000% increase in AI‑search visibility within 90 days and the potential to close six‑figure enterprise contracts. The session is led by...

DoT Strengthens Telecom Safety Push, With Sanchar Saathi at Its Core
India’s Department of Telecommunications is intensifying its focus on user‑centric security through the Sanchar Saathi platform. The app gives individuals visibility into every mobile number tied to their identity and lets them flag unknown connections. Features such as Chakshu reporting,...
GE Aerospace Expands AI to Full Production, Slashing False Alarms by 50%
GE Aerospace has moved its artificial‑intelligence tools from pilot projects into full‑scale production, cutting false engine‑alarm alerts by more than half and accelerating lead times by over 60%. The shift follows a three‑fold increase in AI spending and a strategic...
Instant AI Workspaces Turn Adoption Into Competitive Edge
99% of Ramp uses ai daily. but we noticed most people were stuck — not because the models weren't good enough, but because the setup was too painful and unintuitive for most. terminal configs, mcp servers, everyone figuring it out...
Gemini Live 2.5: Best, Fast, Smart Voice Agent
It’s official, Gemini Live 2.5 voice agent is the best It’s smart, it’s fast, it has large enough context Coming to GBrain Voice shortly

Scale AI Autonomy by Climbing Permission Ladder, Not Skipping Steps
This isn’t a “learn AI agents” roadmap. It’s a permission ladder for autonomy. Skills → memory → coordination → control → monetization. Skip steps and you don’t get scale — you get outages. https://t.co/Z6mgmIIIFj
China Deploys Robots to Revolutionize Hospital Operations
How China Is Transforming Hospital Operations with #Robots by @Arcfunmi #Healthcare #MedTech #HealthTech #TechForGood https://t.co/Tx2XMAoO8i

Lily Pond Myth Reveals AI’s Exponential Doubling
The Great Doubling: What the Lily Pond Myth Teaches Us About the AI Singularity by @Timothy_Hughes https://t.co/2ON532sDsl @DLAIgnite #SocialSelling #DigitalSelling #Sales #SalesTips #SalesLeader #Salesforce #Marketing #Leadership #ArtificialIntelligence #Innovation #Technology #Tech #TechNews
2027 Mercedes CLA 250+ Redefines Intuitive Self-Parking
I don’t use the auto park assist feature in many cars since I can park faster on my own manually, but the 2027 Mercedes-Benz CLA 250+ has one of the most intuitive self parking features I’ve come across. @MercedesBenz @mercedesbenzusa @raybanmeta...
Human Inquiry Skills Gain Value in AI Era
The rise of AI will massively increase the value on being able to generate new information that isn't yet available in digital form. Can you call people and ask questions? Can you observe things in a systematic way? Can you...

Looking for Beginner-Friendly High‑Status Vulnerability Recommendations
What’s a good high status vulnerability for someone just getting into high status vulnerabilities https://t.co/clyMBT4YLd

Assess Your AI Product’s Market Readiness Today
Is Your #AI Product Ready For The Market? by @AlKingsley_Edu @Forbes Learn more: https://t.co/EHIgSEH3P6 #ArtificialIntelligence #MachineLearning #ML https://t.co/iS5lKrrWrp

Recruiting Insights: AI-Era Policy, LinkedIn Trends, Automation Future
Recruiting Brainfood - Issue 496 https://t.co/SB7HuuZ53v Industrial Policy for the Intelligence Age, What LinkedIn posts can tell us about what's happening in recruiting, Global TA benchmark report and an ancient dream of replacing humans with machines... https://t.co/0QehAKuPxK
Automate SEO Title Tags with AI for Instant CTR
Why are SEOs still manually writing title tags when Claude can generate 20 variations optimized for CTR and search intent in 15 seconds? Just plug your Ahrefs, GA4, GSC, build your dashboard, plug your CMS, monitor the situation and approve...

East Coast Urban Corridor Deserves Japan‑Style High‑Speed Rail
It seems pretty reasonable to me that the dense urbanism that extends from Boston to Miami should be connected by high-speed rail, as in Japan. https://t.co/oPwSqixSot
Seeking B2B Software Partner for Free 60-Day AI Search Pilot
I am looking for ONE B2B software company with killer SMEs that is willing to test a pilot program with me for AI search viz via @LinkedIn. This is a 60-day experiment around a real, currently untapped research question, and...