Agenus to Host March 2026 Stakeholder Webcast Harnessing the Immune System to Advance BOT + BAL Across Tumor Types and...
Agenus announced a March 31, 2026 stakeholder webcast to detail progress on its botensilimab and balstilimab (BOT + BAL) immunotherapy program. The company highlighted clinical durability across multiple tumor types, with roughly 1,200 patients treated with botensilimab and over 900 with balstilimab in early‑stage trials. Executives will also discuss expanding global patient‑access pathways, including France’s AAC and Named Patient Programs. The webcast will outline Agenus’ strategic priorities for 2026 as it seeks broader adoption of its combination therapy.
Ask Roman Yampolskiy a Question!
Renowned AI safety scholar Roman Yampolskiy, a tenured associate professor at the University of Louisville, will appear in Los Angeles tomorrow for a public discussion on whether artificial intelligence poses an existential threat. Yampolskiy, who helped coin the term “AI safety”...
How I'm Making $150k+/Mo From the "A.I Boom"
The 2024 AI boom has turned the longstanding 15:1 global software wage gap into a capital‑light arbitrage opportunity, allowing solo entrepreneurs to coordinate offshore developers without writing code. Small businesses, exemplified by roofing contractors, lose up to $520,000 annually to...
Amaze Holdings Announces Creator Commerce Media Platform, Designed To Unlock Data-Driven Revenue Streams
Amaze Holdings launched a Creator Commerce Media Platform to monetize its first‑party commerce and audience data. Built on its new demand‑side platform, the service offers four high‑margin products—DSP audience segments, subscription data SaaS, data‑driven brand activation, and enterprise creator‑intelligence tools....
Roko’s Basilisk: A Dangerous Thought About Deadly AI
Roko’s Basilisk, a 2010 thought experiment from the LessWrong forum, imagines a future superintelligent AI that could retroactively punish those who failed to help its creation. The scenario relies on the AI’s perfect simulation abilities to identify past non‑contributors, turning...
GetHealthy Launches Script, an AI-Enabled Platform Expanding Practitioner Commerce Beyond Supplements Across Seven Product Categories
GetHealthy unveiled Script, an AI‑enabled clinical scripting platform that lets health practitioners prescribe comprehensive protocols across seven product categories, from supplements to pet health and diagnostic testing. The solution taps a catalog of over 400 vetted brands and integrates with...
Mastercard Explores Sale of Nets Real-Time Payments Business
Mastercard has engaged investment bankers to explore selling the real‑time payments business it bought from Denmark’s Nets in 2019 for $3.2 billion. The unit, which produces roughly $370 million in revenue and $100 million EBITDA, is expected to fetch a price below its...
Zapier Stopped Work for a Week and Hit 97% AI Adoption
Zapier’s AI adoption surged from 10% in early 2023 to 97% by early 2026, embedding AI agents into daily workflows for its 800‑person global workforce. The transformation resulted from a four‑step structural intervention rather than traditional training or licensing. This...
Apple Discontinues the Mac Pro ↦
Apple confirmed the discontinuation of the Mac Pro, removing its product page and redirecting visitors to the general Mac homepage. The company also stated it has no plans to release future Mac Pro hardware. The decision follows a shift toward...
Boing Boing, March 26, 2026
Boing Boing’s March 26 2026 roundup spotlights three off‑beat tech stories. A dermatologist installed red LED panels in his son’s hospital room, prompting a fresh look at light‑based therapies for pediatric care. Researchers cloned a mouse 58 times, pushing the limits of...
Even If You’re Just Transiting Hong Kong, Refusing To Unlock Your Devices Is Now A Crime
Hong Kong has amended its National Security Law, making it a criminal offense to refuse police access to passwords or decryption assistance for any personal electronic device. The rule applies to all individuals, including U.S. citizens, whether arriving or merely transiting...
Cops Used AI to Match a Photo to an Innocent Grandmother in Tennessee, Then Jailed Her for Nearly 6 Months
Police in North Dakota used AI facial‑recognition software to link a blurry suspect photo to Angela Lipps, a 71‑year‑old grandmother who had never left her Tennessee hometown. Despite her lack of travel history, officers raided her trailer, arrested her at gunpoint...
Frank Harrell on Why and How to Do Bayes for Clinical Trials and the Recent FDA Draft Guidelines
Frank Harrell, a former FDA statistician, responded to recent JAMA commentary on the agency’s draft guidance promoting Bayesian methods for clinical trials. He highlighted that while the guidance is a step forward, FDA reviewers still rely on traditional frequentist approaches...
Free Wine From Last Bottle Wines Via Referral
Last Bottle Wines is offering free ground shipping on all orders and a $10 credit for new customers who sign up via a referral link. Existing referrers earn a $30 credit when someone uses their link. Wines are priced $8‑$12...
![[Targeted] AmEx Offer: Use Apple Pay Three Times & Receive $10 Statement Credit](/cdn-cgi/image/width=1200,quality=75,format=auto,fit=cover/https://www.doctorofcredit.com/wp-content/uploads/2018/06/amex-offers.png)
[Targeted] AmEx Offer: Use Apple Pay Three Times & Receive $10 Statement Credit
American Express has re‑issued a targeted offer that grants a one‑time $10 statement credit once cardholders complete three purchases using Apple Pay on an eligible mobile device. The promotion, which cycles periodically, is currently active through May 21, 2026 for qualifying AmEx cards....
ETA Prime Answers the Question: What if the MacBook Neo Had Thermo-Electric Cooling?
The MacBook Neo, a low‑cost laptop powered by Apple’s A18 Pro, suffers from rapid thermal throttling because it lacks active cooling. ETA Prime first applied a copper plate and thermal pad to move heat to the aluminum chassis, which already...
Traffic Violation! License Plate Reader Mission Creep Is Already Here
A recent 404 Media report reveals that Georgia State Patrol used a Flock Safety automated license plate reader (ALPR) to issue a traffic ticket for a motorcyclist holding a phone, contradicting the vendor’s claim that its technology is not employed...
Here’s What I’m Building.
The author’s Gumroad store collapsed, prompting a full rebuild under a new LLC called The Biblical House. The venture consolidates three content streams—Biblical Man, Dead Hidden, and Biblical Womanhood—into a single storefront. Upcoming releases include refreshed digital guides, video teaching,...
Version 3 of VDA 5050 Is a Toolkit for Automation Projects
VDMA Materials Handling has launched VDA 5050 version 3.0, an open communication interface that lets a single controller manage mixed fleets of mobile robots. The update adds a zone‑based navigation model, path‑sharing capabilities, localized error reporting and a standardized power‑saving...
What Does the White House AI Framework Mean for Free Speech?
The White House unveiled a new AI framework aimed at guiding the development and deployment of artificial intelligence while safeguarding democratic values. Among its provisions are requirements for transparent labeling of AI‑generated content and mechanisms to curb deepfake misinformation. The...
Pharmaceutical Executive Daily: Trump Administration Misses Deadline to Nominate Permanent CDC Director
The Trump administration failed to meet the 210‑day deadline to nominate a permanent CDC director, leaving the agency without confirmed leadership for most of the second term. Meanwhile, the FDA granted accelerated approval to Denali Therapeutics’ Avlayah, the first enzyme...
Google Brags About Android Web Browser Benchmark Scores on Unnamed Devices; Gullible Reporters Fall for It
Google’s Chromium blog announced that Android flagships have set new records in the Speedometer 3.1 and LoadLine web‑browser benchmarks, claiming the platform is now the fastest for mobile web browsing. The post does not name the devices or software versions, and...
Demand for Legal Engineers Skyrockets in the AI Age
The legal‑tech market is witnessing a rapid surge in demand for legal engineers as generative AI reshapes contract analysis, compliance automation, and litigation support. Job postings for legal engineers grew 48% year‑over‑year in the first quarter of 2026, with median...
Designer Carbon Materials Enable CO2 Release Below 60 Degrees Celsius
Researchers at Chiba University have created nitrogen‑doped carbon adsorbents called viciazites that release captured CO₂ at temperatures below 60 °C, far lower than the >100 °C needed for conventional amine scrubbing. By positioning nitrogen functional groups adjacently on the carbon surface, the...
True Positive Weekly #154
The latest True Positive Weekly curates a snapshot of AI research and industry signals, highlighting the persistent gap between hype and real AI applications. It showcases an interactive GPT‑2 visualization, a deep dive into AI chip hardware‑software co‑design, and a...
8 Key Features to Look for in a Sublimation Printer
The article outlines eight essential features to evaluate when selecting a sublimation printer, from print resolution and speed to ink compatibility, connectivity, and maintenance. High dots‑per‑inch output delivers sharper graphics, while faster machines meet tight production deadlines. Versatile ink support...
Honeycomb CEO on the 30-Second Fix that Took Hours
Christine Yen, CEO of Honeycomb, recounts a 13‑year‑old outage at Parse that exposed a critical visibility gap, later solved by Facebook’s Scuba tool. The experience inspired her to build Honeycomb, a real‑time observability platform that links infrastructure metrics to business‑level...
What Is an AI Presentation Maker for PowerPoint? (Full Guide)
AI presentation makers embed directly within PowerPoint to automatically generate and edit slides based on simple prompts, documents, or web content. They streamline the creation process by handling structure, design, and speaker notes, cutting draft time from hours to minutes....
The Pulse: Is GitHub Still Best for AI-Native Development?
GitHub’s reliability has slipped to roughly 90% uptime, equating to about nine hours of downtime per year. The decline is linked to surging traffic from AI‑powered coding agents and a perceived leadership vacuum after the CEO’s departure. A third‑party status...
TACC Launches CFDE Cloud Workspace for NIH Common Fund Datasets
The Texas Advanced Computing Center (TACC) has publicly launched the Common Fund Data Ecosystem (CFDE) Cloud Workspace, a collaborative effort with Johns Hopkins, Penn State and the San Diego Supercomputer Center’s CloudBank. The platform gives researchers instant, no‑cost access to...
ICC Launches Aquarius R-117A Immersion-Native 1U Server with 6 NVIDIA H200 GPUs
ICC unveiled the Aquarius R-117A, an immersion‑native 1U server that packs six NVIDIA H200 SXM GPUs and a single‑socket AMD EPYC Turin processor with up to 192 cores and 3 TB DDR5 RAM. The system delivers 846 GB of combined GPU memory...
How to Leverage Claude for Data Analysis
Anthropic’s Claude Code helped a sales team produce a full data‑analysis case study in under an hour, turning natural‑language goals into Snowflake SQL without direct data access. By leveraging an existing dbt project, Claude iteratively generated and refined queries, quickly...
Why Best-of-Breed Beats All-in-One for Revenue Managers
Hotel IQ and RateGain have announced a strategic partnership that merges Hotel IQ’s internal business intelligence with RateGain’s competitive rate intelligence. The integration delivers a single‑sign‑on, real‑time view of pacing data and competitor pricing, powered by an AI engine that...
Silicon Insurance: Why eFPGA Is Cheaper Than a Respin — and Why It Matters in the Intel 18A Era
As semiconductor nodes become ever more complex, the financial risk of ASIC respins has surged, with mask sets at Intel’s 18A process costing tens of millions of dollars. Embedded FPGA (eFPGA) offers "silicon insurance" by embedding reconfigurable logic that can...
How to Spot Artificial Intelligence Recruiters Who Target Candidates From LinkedIn
Research firm Gartner predicts that by 2028 one in four job candidates worldwide will be fabricated, fueling a surge in AI‑generated recruiter outreach. Executives are receiving polished, generic emails that often originate from Gmail accounts and contain vague role descriptions,...
Spacebring Launches Lem AI Agent For Coworking Space And Flex Office Operations
Spacebring, a platform serving more than 500 coworking locations worldwide, has launched Lem AI agent to automate routine administrative tasks. The AI assistant handles support ticket triage, retrieves operational data via natural‑language queries, and drafts community communications. Lem AI is...
Opt-Out Is Not Consent
GitHub announced that, starting April 24, it will automatically use interaction data from Copilot Free, Pro, and Pro+ individual users to train its AI models unless users manually opt out. The data includes code, file names, repository structure, cursor context,...
The Rise of the AI Super Agent: How HIX.AI 2.0 Is Redefining the All-in-One AI Workspace
HIX.AI 2.0 launches an all‑in‑one AI workspace that replaces fragmented tool stacks with a Coordinator‑driven, autonomous task planner. The platform combines research, data structuring, multi‑format content creation, and lightweight coding into a single, skill‑based architecture. Users can initiate complex workflows—such...
Creator Economy Briefing: Alix Earle Launches Skincare Brand, Unilever Appoints Influencer Agency, Ambassador Marketing Gains Traction
Today's creator‑economy briefing highlights a shift toward long‑term ambassador partnerships, the rise of influencer‑turned‑founders, and enterprise‑level investments in structured influencer programs. Brands are replacing one‑off campaigns with ongoing creator relationships to boost credibility, while Alix Earle launched her skincare line...
‘No More Energy Bills’: Housebuilder Adopts Finnish Timber System Touted as Better than Passivhaus
Oakmont Contracting has partnered with Finnish firm Talo to adopt its four‑decade‑old panellised timber system for new UK homes. The off‑site method promises to cut construction time by roughly half and eliminates traditional concrete foundations. Talo’s dry‑kilned Nordic timber delivers...
Vision Pro and Cosm: Two of a Kind?
Apple’s Vision Pro delivers impressive hardware and natural displays, yet it lacks the daily content cadence needed to become a habit‑forming device. The article points to Cosm, a high‑end immersive venue where fans pay for shared sports experiences, as proof...
Scoop: Meta Gets Ready to Launch Two New Ray-Ban AI Glasses
Meta and its hardware partner EssilorLuxottica are preparing to launch two new Ray‑Ban AI glasses, as indicated by recent FCC filings that list the devices as production‑ready units. The filings suggest the models are close to market, echoing the rapid...
The "Negative Space" Prompting Technique
A robotics startup in the Pacific Northwest struggled with AI‑generated documentation that hallucinated features and added marketing fluff, delaying product launch. The engineering team’s standard prompts produced inaccurate safety manuals and API docs, requiring extensive manual editing. The author introduced...
Transistor-Inspired Triboelectric Nanogenerator Powers Human-Machine Interfaces without Batteries
Researchers at Chonnam National University unveiled an air‑breakdown triboelectric nanogenerator (AB‑TENG) that harvests static electricity from human skin to power ultrathin input devices without batteries. The device delivers up to 290 V and 22 mW at a modest 24 N contact force, outperforming...
How to Finance Your Store’s Transition to Agentic Commerce
Shopify merchants generating $250 K‑$5 M annually are urged to adopt agentic commerce—a AI‑driven model that boosts conversion and average order value—while preserving cash flow. The article outlines a financing framework that leverages equipment‑technology loans, leasing, and vendor‑financing to fund AI infrastructure...
Prusa Firmware Update Speeds MMU3 Filament Swaps
Prusa Research released firmware version 3.0.4 for the Original MMU3, trimming the average filament‑swap cycle from 52 seconds to roughly 42 seconds – a 20% speed gain. The update can shave up to nine seconds off each swap, translating into hours...
ByteDance Rolls Out Seedance 2.0, as OpenAI Scraps Sora
ByteDance unveiled Seedance 2.0, a text‑to‑video model that produces near‑Hollywood‑quality clips, prompting immediate backlash from major studios over potential copyright infringement. The company paused its global rollout while expanding the service in Africa, Latin America, the Middle East, and Southeast...
Scaling the Flow: Why Integrated Plumbing Software Is the Modern Technician’s Best Tool
Integrated plumbing software is reshaping how contractors manage dispatch, sales, and payments, moving the industry from paper‑based chaos to real‑time digital ecosystems. Tools like Workiz provide GPS‑driven dispatch, on‑the‑spot invoicing, and digital price books that let technicians close sales in...
Programmable Metasurface Achieves Beam Scanning and Multi-Band Radar Cross-Section Reduction
Researchers at Xidian University unveiled a programmable metasurface only 0.065 wavelengths thick—87% slimmer than traditional stealth designs—that can dynamically steer beams and suppress radar signatures. The 12 × 12 prototype scans ±45° at 5.2 GHz with a 17.23 dBi peak gain while delivering more than ‑6 dB...
Argonne Researchers Develop AI System to Enhance Electric Grid Efficiency and Reliability
Argonne National Laboratory unveiled GridMind, an agentic AI co‑pilot that lets power‑grid operators run scheduling, weather‑impact and reliability simulations through natural‑language conversation. The system uses a multi‑agent architecture coordinated by large language models such as GPT‑5, GPT‑4o and Claude 4 Sonnet,...