One‑sentence AI Pipeline Transforms Drug Discovery Workflow
What if your next drug discovery pipeline started with one sentence, not 6 months of scripting? In this latest deep dive with @scispace, I saw a shift that feels bigger than incremental AI gains. Upload single-cell data and get clustered cell types, UMAPs, marker annotations, causal gene rankings, and ADMET analysis in one structured flow. This changes the operating model. Here’s the breakdown…
China Deploys Drones for High‑Rise Fire Rescue
China Unveils #Drone Firefighting Tech for High-Rise Rescue and Fire Control by @MarchUnofficial #Innovation #EmergingTech #Technology #Tech #TechForGood https://t.co/X3TFjnP0XV
Use Gen AI to Argue Bull and Bear Views
Jeremy https://t.co/SHKmqpIutV, you’d instead use gen AI tools to argue the bull and the bear arguments https://t.co/QnEXYv9D2P
India Adds 44.6 GW Solar, Hits 150 GW Milestone.
India just smashed the 150 GW solar milestone >Added 44.6 GW of solar in 1 year, up 87% y-on-y (that's more than the total installed solar capacity of the UK or Spain) >Global solar leaderboard shifting fast: India now 3rd largest solar...
AI‑Engineered Steel Boosts 3D‑Print Strength, Cuts Costs
🔺 Scientists use AI to create ultra-strong, rust-proof steel for 3D-printed parts New AI-designed steel delivers high strength, flexibility, and rust resistance while cutting cost and processing time for 3D printing. https://t.co/hbm3AUGt2z https://t.co/b3vLdGRclh
Delay Cookie Consent Until Interaction to Boost Conversions
Full-Screen Cookie Banner are the biggest conversion killer. You know that you can delay consent (and tracking) until the visitor interacted (e.g. scrolled a bit) with you page? So that user get a chance to understand if your offering is...
Aging
RIP Dr Skulachev who made serious contributions to the ROS theory of aging. Unfortunately, no FDA-approved drug out of his work yet. One of my goals is to have several FDA approved drugs before or after I die. Papers and...
Digital Dashboards Need Retro Flair, Not Just Beach Vibes
10/10. Modern digital dashboards really should get a bit more creative and offer a retro theme too. Unlike... *checks notes* a bloody beach theme on the MBUX Hyper screen.
Claude AI Grows Tomatoes Autonomously for 100+ Days
Anthropic’s Claude #AI #Autonomously Grows Tomatoes for 100+ Days in Groundbreaking Experiment by @d33v33d0 #ArtificialIntelligence #MachineLearning #ML https://t.co/lhMuLS70zA
Samsung Drops Native Messaging App From Default in 2024
@MKBHD @WVFRM RE Samsung messages It was 2021 when Samsung started pre installing Google Messages, but Samsung Messages was on the phone as well. 2024 is when Samsung's messaged wasn't included out of the box, and had to be downloaded...
Autonomous Agents Turn Compute Into Unlimited Demand
My take: When agents are free to work, chat, design, code, buy, sell, and self-organize 24/7 the demand for compute will become limited only by compute availability itself. Agents are Jevons Paradox embodied.
Tree‑Climbing Pruning Robot Outpaces Monkeys
Faster Than a Monkey: This Tree-Climbing Pruning #Robot Is Wild by @IntEngineering #Robotics #Engineering #ArtificialIntelligence #Innovation #Technology https://t.co/7Hldaa6bJU
Kuvera's Decline Drives Users to New
The enshittification of Kuvera has begun, with Cred "revamping" the app. What mutual fund app is now everyone moving to?
Over the Moon After Seven Hours of Stunning Recovery Images
So many amazing images at recovery. What is your fav? I'm quite figuratively "over the moon" having watched everything unfold over the past 7 hours.
AI Chat Slows Down when Browser Tab Loses Focus
Does it feel like your AI slows its response if you leave the browser tab? Is this just me?
Artemis II’s 3D Flight Path to the Moon
Artemis II mission route in 3D! https://t.co/MwqPxMYofs #artemis #ArtemisII #moonmission #moon #journeytomoon #space #SpaceLovers @lexfridman @KirkDBorne @Ronald_vanLoon @erikbryn @antgrasso @sallyeaves @Nicochan33 @HaroldSinnott @mvollmer1 @marcusborba @CatherineAdenle @vinod1975 @YuHelenYu @ingliguori @fogoros @ylecun @TerenceLeungSF @SourabhSKatoch @wil_bielert @HsrYueli @faustospain @Whats_AI @kaifulee @demishassabis @marek_rosa @AndrewYNg @BernardMarr...
Frontier AI's Rapid Threat Looms if Misused
We live in such a perfect world considering where frontier AI could easily take us in under a year if the villains were a bit more creative. Some of the very realistic ideas that are on the surface I am...
Starlink Group 17‑21 Launches From Vandenberg at 0504 UTC
LAUNCH at 0504 UTC Apr 11 of Starlink Group 17-21 from Vandenberg Space Force Base
Huawei’s Fold Signals the Dawn of Post‑Keyboard Computing
Huawei may have just shown where personal computing is heading next. And it looks a lot less like a traditional laptop. The MateBook Fold takes an 18.3-inch OLED display, folds it like a book, and turns it into a smaller 13-inch device...
S Plus Production Slumps, Edge Model Likely Replacement
Galaxy S Plus is not lasting another generation. Might not even last this one. Production breakdown: S26 Ultra: 1.5 Million S26 Plus: 200K S26: 1.3 Million S26 Plus is getting dangerously close to S25 Edge level production. At this point I'd just launch the S26...
Yudkowsky’s Double Talk: Safety Proposals vs Bomb Threat
“Yudkowsky talks out of both sides of his mouth. He wants us to believe that his proposals for avoiding an AGI apocalypse are within the bounds of established norms, yet in a moment of honesty he says that he would...
AI Agent Integration Still Stuck in Altair BASIC Era
Yes, this is indeed a somewhat frustrating setup to get OpenClaw + GBrain + LLM Knowledge Wiki talking to your phone. These are all things that need to be fixed. We're in the Altair BASIC era of AI agents. (Screenshot below...
Designing Legible AI Codebases & Embracing Friction
AI Engineer conference in Europe is pretty good. A few slides from Armin Ronacher's talk: Designing agent legible codebases and embracing friction links below
Brain‑Inspired AI Delivers Scalable, Energy‑Efficient Parallel Computing
We absolutely must understand how the brain works to solve brain diseases. @unconvAI is taking inspiration from the brain, and is ultimately solving a different problem: it is building machines that can solve many problems in parallel in a massive...
BYOAI's Rise Brings Huge Governance Risks for Untrained Users
BYOAI Revolution: Why “Bring Your Own AI” is the new BYOD and the massive governance risks of an illiterate workforce building their own bots https://t.co/rHwTssIIiG via @DLAIgnite #SocialSelling #DigitalSelling #Leadership #ArtificialIntelligence #TechNews #AgenticAI #AIAgents #AI
Moya: First Biomimetic AI Robot Mimics Human Expressions
Meet Moya: World's First 'Biomimetic AI Robot' That Can Bend, Smile and Wink with Unsettling Human-like Accuracy https://t.co/37i9oYo8rd #biomimetic #humanoidtech #humanoid #robot #Robotics #AI #TechRevolution #TechInnovation #ArtificialInteligence #PhysicalAI @SpirosMargaris @PawlowskiMario @mvollmer1 @gvalan @ipfconline1 @LaurentAlaus @Shi4Tech @Fisher85M @kalydeoo @Ym78200 @Nicochan33 @chboursin @3itcom @Fabriziobustama...
AI Turns Knowledge Work Into Mass‑Produced Synthetic Labor
AI is synthetic labor. It gives us the ability to mass-produce knowledge labor itself. And accelerate it. The implications are incredible and terrifying.
New IDS Enhance SCADA Cybersecurity Protection
New intrusion detection systems boost protection of SCADA systems against cyber threats #energysky -- via pv magazine global: https://t.co/110epGR3u2
New GBrain Connectors Enable Agent Chat and Phone Calls
Two things I'm excited to ship for GBrain for the next 36 hours: Connectors to Claude Cowork / Perplexity Computer so your GBrain can talk with the locked down agents via MCP GBrain Skillpack that will let you have Call-Your-Claw-By-Phone via Twilio...
Waymo's Scattered Rollout May Avoid Rapid
Why does Waymo spread their cars across dozens of cities? They should completely saturate one city til they match Uber’s pick up times. I assume they’re trying to lose because winning in self-driving means putting too many people out of work,...
Hawai‘i Campus Adds Solar Carports with Battery Storage
University of Hawai’i branch campus to install solar carports with battery system #energysky -- via Solar Power World: https://t.co/mP7B0rliLk
WA Households Miss Negative Pricing, Boosting Solar‑battery Push
In Western Australia, domestic customers don't have access to negative pricing events - because? @SynergyEnergy How about it @RogerCookMLA - a further incentive to put solar into batteries - and into batteries on wheels?
Monopoly Go!Chat Hits #1, Learning App Store Secrets
up to #3, coming for the crown 👑 that being said, MONOPOLY GO!Chat is now #1, so i’m learning a lot about the App Store https://t.co/Vz1pwoxdpY
Building Apps That Profit and Save Lives During Floods
Building a profitable app feels great, but even better: Building tech that helps people in need. @kurbaitaev seeing a dangerous flood hit his home country Dagestan by doing what he does best: Building. The app quickly went viral and empowered many...
Data Centers Face 2026 Ballot, Fail Initial Test
Data centers are on the ballot in 2026 — and just failed the first test #energysky -- via Canary Media: https://t.co/T5JkqFSW8w
Magnetic Privacy Filter Shields MacBook From Shoulder Surfers
Tired of shoulder surfers seeing everything on your MacBook screen when working in public? Then you'll want to learn all about the Afterplug Magnetic Privacy Filter Screen, which I demo and test in my latest review video: https://t.co/dVTvZyGDMc #privacy #macbook...
LLM Drafts Are Useful, but Require Careful Human Editing
Amazing how many established leaders and intellectuals think they can fool everyone with pure llm generated writing. Pangram 100% level It can be very helpful to get a draft of a sentence or paragraph from an LLM…but how do you not...
Human Cells Lag Far Behind Yeast in Large DNA Integration
“Ultra large” in this paper is 8 kb 😭 > shows how far we are from achieving the sort of SynBio we routinely do in yeast in primary human cells. 50 kb integrations are fairly routine in yeast
Disable Adaptive Reasoning on Opus & Sonnet via Env Variable
To disable adaptive reasoning on Opus 4.6 and Sonnet 4.6 and revert to the previous fixed thinking budget, set CLAUDE_CODE_DISABLE_ADAPTIVE_THINKING=1. When disabled, these models use the fixed budget controlled by MAX_THINKING_TOKENS. https://t.co/sPAkOwVB9C
A Proxy Without SLOs Is a Liability
Your proxy is either a guardian or a liability. There’s no in-between. If it doesn’t have its own SLOs, timeouts, and runbook — it’s not a safe proxy. It’s a false sense of security with a load balancer in front. 🫥 What’s yours running...
Substack's In-App Payments Set for Global Rollout by Mid‑2026
Substack in-app payments haven't become a big thing yet, as they're only available in the US and a few other countries. But I think they'll be rolled out globally by mid-2026 https://t.co/iHQrkcgbb6
AI‑generated Fact Checks Win Broader, Less Biased Approval
Neat experiment finds AI fact checks are rated as more helpful & less ideological than human ones "LLM-generated Community Notes can achieve broader cross-ideological acceptance than human-written notes, receiving more positive ratings from raters across the political spectrum" https://t.co/Ofg1kYNxYe
SaaS Buybacks Soar While Companies Remain Deeply Underwater
software is trying to catch a falling knife SaaS companies have announced >$70B in buybacks this year… almost all are underwater
Artemis II Nails Precision: Distance, Speed, Reentry on Target
Artemis II return stats, per flight director Rick Henfling (via FDO): • Distance traveled: 700,237 miles • Top speed: 24,664 mph • Reentry angle: Within 0.4% of target • Entry distance: 1,957 miles • Landing location: Within 1 mile of target
Colorado Aerospace Powers Artemis’s Record‑Fast Reentry
An incredible moment for American innovation and exploration. As NASA’s Artemis mission returns to Earth, astronauts are reentering our atmosphere at speeds nearing 25,000 mph — among the fastest speeds ever traveled by humans. Colorado is proud to play a role in...
Coding AI Voice Agent by Pool, Dynamic VAD Works
I don’t even know what is going on with software anymore because I’m by a pool in Kona Big Island right now and coding my personal AI voice agent by chatting with it on Telegram on my iPhone while sipping...
Renewables and Nuclear to Power Half of World by 2030
The IEA expects renewables and nuclear to provide half of global electricity by 2030 as power demand accelerates. https://www.metalnomist.com/2026/04/clean-power-growth-will-reshape-global.html
Layers Makes Demo Video Creation Super Easy
Layers is one of my favourite tool and creating demo videos are now super easy
Artemis Returns Safely, Celebrating Humanity’s Space Triumph
Artemis home, safe in the sea, Millions watched, one HUM-AN-ITY. From questions asked to answers flown, Science made the unknown… known. To every hand that shaped the way, Thank you for bringing her home today 🌙 Goodnight, everyone ✌️
Master GPU Latent vs CPU Deterministic in 2026
Open source and knowing what goes in latent space (GPU) and what goes in deterministic space (CPU) ^^ the defining concepts to know and implement in 2026
