Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
Utah’s Department of Health has green‑lit a 12‑month pilot that lets an approved artificial‑intelligence system automatically process prescription refills for chronic medications. The AI checks dosage, patient history, and insurance eligibility before sending the order to participating pharmacies, aiming to cut pharmacist workload and boost adherence. The program will enroll up to 5,000 patients and operate under strict state‑approved algorithmic oversight. It arrives amid a growing wave of state‑level health‑AI regulations following recent federal guidance on digital health tools.
Researchers have engineered miniature, three‑dimensional spinal‑cord organoids that can be deliberately injured and subsequently repaired with a biocompatible gel. The gel promotes cell survival and rapid axonal regrowth, effectively modeling the healing cascade observed in vivo. This human‑derived platform provides...
The United Kingdom and Brazil have issued safety warnings linking GLP‑1 weight‑loss drugs to acute pancreatitis after recording 19 and 6 deaths respectively. Reports include roughly 1,300 UK and 145 Brazilian pancreatitis cases among millions of users, though the overall...
Amgen reported double‑digit revenue and earnings growth for 2025, driven by strong performance across its oncology, rare‑disease, biosimilar and general‑medicine portfolios. Fourteen products surpassed $1 billion in sales, with Repatha, Evenity and Tespire each posting over 30% year‑over‑year growth. The company...
![[Correspondence] Why Ukraine's Energy Insecurity Is a Maternal Health Crisis](/cdn-cgi/image/width=1200,quality=75,format=auto,fit=cover/https://hixhlmpcokxhartfkpyi.supabase.co/storage/v1/object/public/images/thumbnails/b09028a36dc3b49cdea2e70aeb73b513.webp)
The Russian invasion has turned Ukraine’s energy grid into a weapon, leaving maternity hospitals without reliable power, heat, and medical equipment. Repeated strikes have caused 23 major attacks on health facilities this year, pushing premature‑birth rates to twice the national...
ViVE 2025 convened leading health‑tech innovators to examine how security, artificial intelligence and other emerging technologies are reshaping digital health. Speakers highlighted AI‑driven diagnostics, robust cybersecurity frameworks, and interoperable platforms as essential for scaling patient‑centric care. The event also showcased...
A collaborative team led by UNSW and Nutromics has demonstrated a wearable patch that continuously measures vancomycin levels using DNA‑based aptamer sensors. Published in Nature Biotechnology, the pilot trial showed the patch can track drug concentration in interstitial fluid, offering...
The American Hospital Association (AHA) has launched the “We Care, We Vote” campaign to mobilize its member hospitals ahead of the 2026 midterm elections. The initiative offers a dedicated website featuring voter‑registration tools, turnout guides, and a questionnaire that helps...
The National Security Agency has issued a two‑phase Zero Trust Implementation Guidelines to help organizations adopt zero‑trust architecture in line with Department of Defense standards. The guidance details specific activities and requirements, acknowledging that implementation can be resource‑intensive and costly....
Grail’s multi‑cancer blood test Galleri failed to meet its primary endpoint in a large NHS‑partnered study, casting doubt on its early‑detection claims. The test, priced at $1,000, generated $136.8 million from 185,000 units sold in 2025 but remains unapproved by the...
The Administration for Strategic Preparedness and Response (ASPR) announced its first Defense Production Act Title III investment to boost U.S. manufacturing of essential drugs. The funding targets the chronic shortage of oseltamivir, the antiviral known as Tamiflu, by supporting domestic production...
A JAMA study released Feb 18 reveals that 10 % of Medicare Advantage (MA) beneficiaries—about 2.9 million people—must secure alternative coverage for 2026 as plans exit the market, up from 6.9 % in 2025. The displaced enrollees are disproportionately in preferred‑provider‑organization, non‑special‑needs, small‑carrier, and...
What got you here won’t get you there: a physician’s guide to leadership http://dlvr.it/TR3W2k Physician #HealthIT
I've noticed that PE and VC are getting lumped together by healthcare industry folks that I know as if they're the same thing. I'm not sure how we solve this problem but I suspect having more transparent conversations about it...
FDA Commissioner Tracy Beth Høeg, in her inaugural staff address, announced a renewed focus on evaluating the safety of antidepressants prescribed during pregnancy and monoclonal antibody RSV prophylaxis for infants. She highlighted gaps in existing safety monitoring and pledged more...
A key study of $GRAL's Galleri test in the UK failed to reach its primary endpoint, but showed benefits on a secondary endpoint. Tell me what you all think. https://t.co/CDrvokqPop
HopeHealth, a nonprofit health system serving Rhode Island and southeastern Massachusetts, celebrated its 50th anniversary as the nation’s second hospice and highlighted a period of significant growth in hospice and palliative care. CEO Diana Franchitto noted that aging demographics and...
The FDA announced it will drop the historic requirement for two adequate and well‑controlled studies in certain new‑drug approval pathways, a move that could accelerate timelines and lower development costs. The change is especially relevant for therapies targeting unmet medical...
Novo Nordisk’s shares have slumped 66% from their 2024 peak, reflecting weak 2026 guidance and fierce competition from Eli Lilly in the GLP‑1 arena. The Danish firm recently introduced the first oral GLP‑1 pill, positioning it ahead of Lilly’s upcoming tablet and...
The Advisory Committee on Immunization Practices (ACIP) cancelled its scheduled February 25‑27, 2026 meeting, and no new date has been announced. The cancellation occurs amid a wave of senior HHS leadership changes, including the departure of Deputy Secretary Jim O’Neill and General...
Researchers at Gladstone Institutes discovered that red blood cells (RBCs) act as a primary glucose sink during hypoxia, explaining why people living at high altitude have lower blood sugar. PET/CT scans showed 70% of the extra glucose clearance in hypoxic...
Many thanks to Freedom Together Foundation medical research consortium for hosting my remarks this week @RockefellerUniv discussing our vaccine development program and my work on the history of medical science vs anti-science in America https://t.co/etbLqiezEA
Chronilogix announced an integration that embeds its AI‑powered coaching technology into the Balance for Life wellness app. The combined solution delivers on‑demand behavioral health support for depression, anxiety and stress, while also addressing chronic condition management. By offering 24/7 personalized...
The article outlines the four canonical health‑care system models—Beveridge, Bismarck, national single‑payer, and hybrid—and shows that the United States operates a hybrid structure combining elements of each. It highlights WHO’s six criteria for high‑performing systems and notes that despite world‑class...
Eli Lilly reported that its biologic Omvoh (mirikizumab) sustained steroid‑free remission for three years in Crohn’s disease patients in the Phase 3 VIVID‑2 open‑label extension study. More than 90% of participants remained in remission, with 80% experiencing relief from bowel urgency. The...
Dock Health announced that its productivity platform is now deployed at Mayo Clinic to automate referral and specialty workflows across cardiovascular, e‑consult and contract programs. The solution creates structured, real‑time workflows that trigger when orders enter the EHR, automatically assigning...
A recent open‑access study of 514 Canadian seniors examined peripheral inflammation using IL‑6 and C‑reactive protein. The analysis revealed that elevated IL‑6 levels were present in 12% of cognitively normal participants but rose sharply to 36‑55% among Alzheimer’s, mixed dementia,...
Lonza has expanded its advanced synthesis portfolio to provide end‑to‑end support for antibody‑drug conjugates (ADCs) and other bioconjugates. The company fully integrated the Synaffix‑derived ADC platform—including GlycoConnect® conjugation, HydraSpace® spacers and toxSYN® linker payloads—into its services. A new dual‑payload ADC...
🆕@Nature Genome sequencing of >800,000 people finds Epstein-Barr virus reads and their association with other autoimmune diseases besides multiple sclerosis, including type 1 diabetes, inflammatory bowel disease, and hypothyroidism https://t.co/FKCV4OInT5
The author recounts a recent struggle with Medicare Part D after a prescription fell off the plan’s formulary, raising the out‑of‑pocket cost from the expected $500 to nearly $600. By appealing the denial, the drug was reinstated on the formulary, the...
HHS is intensifying its focus on third‑party vendor security after the 2024 Change Healthcare ransomware attack, which exploited a remote‑access portal lacking multifactor authentication and exposed the data of about 190 million individuals. The breach threatened the liquidity of the entire...
CoverMyMeds outlines how access and affordability challenges evolve across a biopharma brand’s lifecycle, from launch through loss of exclusivity, and offers actionable, data‑driven strategies to mitigate them. The firm emphasizes real‑time analytics, provider‑focused tools, and tailored patient assistance to reduce...
The CMS Transforming Episode Accountability Model (TEAM) now holds hospitals financially accountable for costly surgical episodes, prompting a shift toward true specialist collaboration. Hospitals must craft Collaboration Agreements that align incentives, share data, and avoid punitive scoring to keep surgeons...
GE HealthCare announced FDA clearance for three next‑generation MRI products: the 1.5‑T Signa Sprint with Freelium, the 3‑T Signa Bolt, and the AI‑driven workflow platform Signa One. The Sprint uses a helium‑free magnet that consumes less than 1 % of traditional coolant, while the...
MIT researchers have created a miniature ultrasound system roughly the size of a smartphone and costing about $300, capable of capturing real‑time three‑dimensional breast images. The device uses a square‑array probe with CODA geometry, reducing transducer elements from 1,024 to...
Amazfit, Zepp Health’s flagship wearable brand, launched the T‑Rex Ultra 2, a rugged GPS smartwatch aimed at extreme‑environment users. The device combines comprehensive biotracking—heart rate, SpO₂, sleep, breathing, and stress metrics—with 30‑day battery life, 100‑metre water resistance, and a Low Temperature...
Altesa, run by former Trump official, raises $75M for well-traveled lung drug https://t.co/bUx5dcvNJy by @gwendolynawu #biotech #startups
Researchers used Mendelian randomization to demonstrate that the inflammatory cytokine IL6 directly increases all‑cause mortality, while its soluble receptor IL6R has the opposite effect. Elevated circulating IL6R was linked to lower risk of lung cancer, diabetes, stroke and coronary artery...
Health systems are turning to cloud‑based generative AI to slash documentation overload. City of Hope deployed HopeLLM, an agentic large‑language‑model platform that creates concise medical‑history summaries in minutes, freeing clinicians from nightly “pajama time.” Providence built Provaria on Azure, using...
These proposed reforms to pre-clinical drug development and to smoothing the transition to first-in-human studies could be the most consequential steps toward leveling the playing field with China. https://t.co/oVY6N3xo9Y
Britain’s Labour government is under growing pressure over its contracts with U.S. data‑analytics firm Palantir, which include a £330 million NHS platform and a £240 million defence deal awarded without competition. Critics cite the company’s founder Peter Thiel, its work with ICE, and...
Hims & Hers Health announced a definitive agreement to acquire Australian digital‑health firm Eucalyptus for up to $1.15 billion, with $240 million paid in cash and the balance structured as deferred and earn‑out payments. Eucalyptus, founded in 2019, serves more than 775,000...
The most used multicancer early detection (MCED) blood test (liquid biopsy) uses methylation (GRAIL). But combining that with DNA fragmentomics, as reported today @NatureCancer, improves early detection https://t.co/VkNDR4XuW3
Verdiva Bio, an obesity‑focused biotech, is gearing up for a data‑heavy 2026, with Phase 2 results for its lead long‑acting peptide slated for the third quarter. The company is also courting strategic partnerships, eyeing potential deals with major pharma players after...
CareYaya, a student‑matching platform, connects college students with seniors and disabled adults to provide non‑medical in‑home assistance. By paying students directly at about $20 an hour, the service reduces care costs roughly 50 % compared with traditional agencies. The app’s algorithm...
FDA leaders say one pivotal trial, not two, should be ‘default’ for drug approvals https://t.co/ADRb1miphf by Kristin Jensen #biotech
Vanda Pharmaceuticals received FDA approval for tradipitant (Nereus®), an oral selective NK1 receptor antagonist, to treat motion‑induced nausea and vomiting. The approval marks the first new drug for motion sickness in more than four decades, highlighting a significant regulatory milestone....
BioSpace’s Denatured podcast featured Verdiva Bio’s R&D head Jane Hughes and MitoRx CEO Jon Rees discussing next‑generation obesity therapies that move beyond the limitations of GLP‑1 agonists. They highlighted how GLP‑1 treatments can cause muscle loss and suffer from poor...
MedStar Health is scaling its Signature concierge primary‑care program by partnering with Withings Health Solutions to supply patients with cellular blood‑pressure cuffs and scales. The collaboration leverages MedStar’s existing telehealth and remote‑patient‑monitoring infrastructure to collect real‑world physiologic data outside the...
An analysis by the Parkland Center for Clinical Innovation using its Community Vulnerability Compass finds that four out of five rural Texans live in areas highly vulnerable to life‑threatening chronic diseases. Over 670,000 residents face elevated risk for coronary heart...
