Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves first CIRM‑funded gene‑editing therapy for rare immune disorder
The FDA has granted approval to KRESLADI, a gene‑editing therapy from Rocket Pharmaceuticals that treats severe leukocyte adhesion deficiency‑I in children without a matching bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine (CIRM), highlighting the agency’s impact on translational research.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
A new Trilliant Health analysis shows that hospitals generate only about one‑third of their gross revenue from patient care, with a median of 29.9% in 2024. The share varies widely, from 8.3% to 86.6%, and is lower for for‑profit facilities (28.8%) than for faith‑based nonprofits (49.3%). Nonpatient‑related revenue and expenses now play a substantial role, accounting for roughly 16% of operating costs and supporting many hospitals that posted negative operating margins in 2023. The findings highlight growing financial reliance on investments, grants and ancillary services such as device sales and pharmacy operations.
The U.S. Food and Drug Administration ordered the Greenbrier Clinic in Sulphur Springs, West Virginia, to suspend its mammography services after an American College of Radiology review flagged serious quality concerns. The FDA’s action covers exams performed between October 28, 2023 and...
Nearly 3,000 registered nurses at six Tenet Healthcare hospitals in California ratified a three‑year labor contract with 93% support. The agreement, effective July 1 2025 through June 30 2028, includes wage increases of 11% to 18% over the term, a dedicated rapid‑response nurse at...
Retail giants are accelerating their pharmacy footprints, with Amazon planning same‑day prescription delivery in 4,500 U.S. cities by the end of 2026 and Walmart promoting 3,000 pharmacy technicians while raising wages to $22‑$40.50 per hour. Walgreens and CVS are also...
A Joint Economic Committee report finds Medicare Advantage plans are being paid roughly 20% more than Original Medicare for comparable care, largely due to aggressive coding intensity and favorable selection. These overpayments trigger a mandatory Part B premium pass‑through, adding an...
The Pentagon has asked Congress for a $200 billion supplemental defense budget, a sum that eclipses the entire annual budget of the Department of Health and Human Services. At the same time, the administration proposes an $18 billion cut to the National...
The latest CareTalk episode spotlights the growing crisis of surprise medical bills that trap millions of Americans in debt. Patricia Kelmar of PIRG breaks down patient rights under the No Surprises Act and explains how the law reshapes billing practices....
Researchers at the National University of Singapore have launched a skin‑conforming hydrogel wearable that delivers clinical‑grade ECG and blood‑pressure data while users move, classifying fatigue with 92% accuracy. The breakthrough could give biohackers and employers a continuous, objective view of...
A coalition of hospital stakeholders, including the American Hospital Association, released Long‑Term Acute Care Hospital (LTCH) Reform Policy Principles to guide Congress. The proposals aim to expand payment criteria for high‑acuity patients, improve the prospective payment system, reconsider the 25‑day...
Ontario will cut provincial funding for seven supervised consumption sites in Toronto, Ottawa, Niagara, Peterborough and London, giving them 90 days to wind down. The $378 million CAD (≈$280 million USD) will be redirected to 19 Homelessness and Addiction Recovery Treatment (HART)...
New York‑based Mantis Biotech unveiled an AI platform that builds physics‑based digital twins of humans, producing synthetic biomedical datasets for drug discovery and other high‑risk biomedical research. The startup says the technology can fill data gaps in rare diseases and...
The American Hospital Association (AHA) submitted comments to the Centers for Medicare & Medicaid Services (CMS) on a proposed rulemaking aimed at strengthening the domestic supply chain for personal protective equipment (PPE) and essential medicines. The AHA supports CMS’s plan...
HHS Secretary Robert F. Kennedy Jr announced on a podcast that the federal government will lift restrictions on 14 injectable peptides, allowing compounding pharmacies to produce and sell them without the usual FDA review. The move bypasses the scientific advisory...
BullFrog AI Holdings saw its Nasdaq‑listed shares climb 126.24% to $1.15 after announcing a commercial agreement with a leading global pharmaceutical company. The deal gives the pharma partner exclusive access to a novel target candidate for major depressive disorder and...
Southcoast Health announced the creation of an in‑house police department, deploying a 12‑officer force led by newly appointed chief Marc Duphily. The move follows five years of using Massachusetts State Special Police and is driven by a sharp rise in...
The phase III SCOUT‑HCM trial showed that mavacamten (Camzyos) significantly reduced left ventricular outflow tract (LVOT) gradients in adolescents with obstructive hypertrophic cardiomyopathy (HCM) compared with placebo. Forty‑four patients aged 12‑17 were randomized to weight‑based doses of 2 or 5 mg daily, achieving a...
The American Hospital Association (AHA) responded to CMS’s Request for Information on the Comprehensive Regulations to Uncover Suspicious Healthcare (CRUSH) initiative, urging data‑driven, low‑burden regulatory changes. It called for stronger oversight of Medicare Advantage organizations and enhanced transparency tools for...
The Centers for Medicare & Medicaid Services reported that average out‑of‑pocket premiums for Health Insurance Marketplace enrollees jumped from $113 in 2025 to $178 in 2026, a $65 monthly increase. The rise follows the expiration of the enhanced premium tax...
The Malcolm Baldrige National Quality Award for Performance Excellence was granted to two hospitals—one in New York and one in New Mexico—recognizing their superior patient safety, leadership, and operational performance. Administered by the National Institute of Standards and Technology, the...
Doctors Without Borders has condemned Gilead Sciences for refusing to sell its long‑acting HIV prevention drug lenacapavir directly to the humanitarian organization. The company had previously negotiated a limited‑supply request, while a separate deal with the Global Fund aims to...
The Centers for Medicare & Medicaid Services (CMS) finalized an Interoperability and Prior Authorization Rule that obliges payers to publish annual aggregated prior‑authorization metrics, with the first set due March 31 for calendar‑year 2025. The rule also shortens decision timelines to seven...
Health care hiring remains a primary engine of U.S. job growth, projected to add 693,000 positions by 2025. Without those additions, the broader economy would lose roughly 570,000 jobs, highlighting a stark labor gap. Viventium’s acquisition of Apploi positions the...
Barclay Berdan, CEO of Texas Health Resources, will retire in September after four decades with the system, having overseen major clinical, digital, and operational transformations since taking the helm in 2014. The board has appointed senior executive vice president and...
The Centers for Medicare & Medicaid Services reported ACA enrollment at 23.1 million for 2026, a 5% dip from the 2025 peak but still 8% above 2024 and 41% higher than 2023. New consumer sign‑ups fell 13% to 3.6 million, while returning...
Erbe announced a Class 1 FDA recall of 40,952 single‑use flexible cryoprobes after reports of loud ruptures that injured healthcare staff. The failures were traced to insufficient adhesive application, causing gas‑inlet loosening and tubing bursts outside the patient’s body. At least...
New Zealand’s recent cyber‑security strategy follows high‑profile health data breaches that exposed over 120,000 patients’ records. The government argues that existing privacy legislation does not impose enforceable cyber standards on private IT contractors supporting public health providers. It calls for...
The article warns that expanding clinical authority without matching accountability creates diffuse responsibility that harms patient clarity and safety. It argues that diagnostic uncertainty cannot be captured by metric‑driven systems, leaving physicians to shoulder unmeasurable judgment. The piece calls for...
Eli Lilly’s oral selective estrogen receptor degrader INLURIYO (imlunestrant) received FDA approval on September 25 2025 for adults with advanced ER‑positive, HER2‑negative breast cancer harboring an ESR1 mutation after endocrine therapy failure. The decision rests on the EMBER‑3 trial, which enrolled 874...
Health savings accounts (HSAs) are being promoted by Republicans as a solution to rising healthcare costs, positioning them as a tool for smarter consumer spending. However, experts argue the tax‑advantaged accounts mainly benefit affluent Americans and may shift more expenses...
Merck reported that its experimental oral PCSK9 inhibitor, enlici‑tide, outperformed a range of commonly prescribed cholesterol‑lowering medicines in a head‑to‑head comparator trial. The data bring the drug a step closer to becoming the first oral PCSK9 therapy on the market....
A prospective cohort of 217 opioid‑naive patients undergoing outpatient cervical or lumbar spine surgery revealed dramatic variation in postoperative opioid consumption based on procedure complexity and technique. Single‑level cases averaged 75 MME, while multilevel procedures more than doubled that figure to...
At the American Academy of Dermatology (AAD) meeting in Denver, Takeda, Alumis, Priovant and Incyte each unveiled late‑stage dermatology data, ranging from novel biologics to targeted small molecules. Sanofi and Biogen also presented, highlighting mixed results in eczema and lupus...
Eli Lilly is pressuring the U.K. government to raise NHS drug prices and eliminate the VPAG rebate scheme before it resumes new investment in Britain. The company is also exploring outcome‑based pricing for its anti‑obesity medicines. In parallel, Lilly struck a...
The U.S. Department of Health and Human Services announced a $100 million STREETS program to expand addiction treatment and housing support for people experiencing homelessness. The initiative, part of the Great American Recovery Initiative, will start in eight pilot communities and...
The American Hospital Association’s inaugural Healthier Together Conference will take place May 12‑14 in Dallas, and early‑bird registration rates expire on March 31. The three‑day event will convene health‑care leaders to discuss community‑health partnerships, data‑driven care coordination, and strategies for addressing social...
A longitudinal study of over 4,300 depressed Chinese seniors compared with 43,000 non‑depressed peers found depression dramatically increases dementia risk. Depressed participants were almost five times more likely to develop Alzheimer’s disease and 1.9 times more likely to develop vascular...
Cyril Land’s struggle to secure voluntary assisted dying (VAD) in regional Victoria highlights systemic barriers that persist despite a national rise in VAD usage. A 2026 Go Gentle Australia report shows Victoria recorded only 799 VAD applications last year—well below...
Perth registered enrolled nurse Daniel Luckhurst was struck off after two separate aggressive episodes with vulnerable patients on a psychiatric ward at Bentley Hospital in August 2023. In one incident he seized a phone from an Aboriginal patient and used...
On March 27, 2026 the FDA’s Center for Devices and Radiological Health issued new guidance on incorporating voluntary patient preference information (PPI) throughout a medical device’s total product life cycle. The document supersedes the 2020 guidance and details when and...
Hey @BernieSanders, look up who owns HealthFirst, the insurer that cut off her insurance for a nickel and explain to us all why you are not actively supporting the Break Up Big Medicine Bill ? Why am I calling you out...
Glia-to-Axon Transfer of Ribosomes and miRNAs: A Novel Paradigm in Neural Repair "Schwann cell-derived exosomes thus represent both a novel mode of glia–neuron communication and a promising avenue for next-generation therapies for nerve regeneration." https://t.co/xU3zmkA5OA https://t.co/kK3FrVuN7T
Medicinal cannabis prescriptions are expanding across Australia, yet THC‑containing products can impair driving for several hours. Inhaled doses peak within the first hour and may affect cognition for up to six hours, while oral formulations can linger for eight to...
Really interesting. One of their predictions is 100% success chance for $MLTX in psoriatic arthritis.
Since the FDA ordered a nonprofit to stop shipping fecal transplant material in 2024, patients with recurrent C. diff have struggled to find cures. @EricBoodman documented one mom's long journey to keep her son alive. https://t.co/48ADcDGU0b via @statnews
Choosing laser safety glasses requires matching the eyewear to the specific laser wavelength and power level. Optical density (OD) ratings must correspond to the laser’s wavelength range to provide adequate attenuation. Industries such as manufacturing, healthcare, and research often operate...
Researchers at Liverpool School of Tropical Medicine have discovered a previously undescribed Treponema species strongly associated with noma, a fatal disease affecting impoverished children. Using metagenomic sequencing and machine learning on saliva samples, they identified the bacterium early in disease...
A recent European dermatology study of 73 skin‑biopsy samples shows that pairing traditional dermatopathology with PCR‑based molecular testing markedly improves the ability to distinguish eczema from psoriasis. While pathology alone achieved 76.9% accuracy, the integrated method resolved ambiguous cases and...
Apple’s App Store will now label apps that qualify as regulated medical devices on their product pages in the United States, United Kingdom and European Economic Area. Developers must indicate this status in App Store Connect if their app falls...
