
FDA approves first CIRM‑funded gene‑editing therapy for rare immune disorder
The FDA has granted approval to KRESLADI, a gene‑editing therapy from Rocket Pharmaceuticals that treats severe leukocyte adhesion deficiency‑I in children without a matching bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine (CIRM), highlighting the agency’s impact on translational research.
Also developing:
By the numbers: Syneron Bio raises $150M Series B

The interview with Tina Valbh highlights how prior‑authorization workflows crumble at every handoff, from clinicians to multiple vendors, creating delays and patient confusion. She points out that patients rarely receive real‑time updates, leaving them unaware of denials or required actions. The fragmentation stems from too many stakeholders and poor coordination, turning a cost‑control tool into a barrier to care. Valbh recommends streamlining processes and boosting transparency to turn prior authorization into a seamless, patient‑centric experience.
A decade ago, I used to think "I'm just a dietitian, I'm not a *real* member of the healthcare team that actually matters." Then I realized that I could be the best f*cking advocate my patients had ever had. And that...

This administration let Hewlett Packard Enterprise keep Juniper Networks, settled with Ticketmaster, and let Google keep Chrome. But healthcare keeps being the exception. The Federal Trade Commission's new Healthcare Task Force looks like the beginning of a coordinated enforcement apparatus...

FTC Chairman Andrew N. Ferguson announced a new Healthcare Task Force that merges the Bureaus of Competition, Consumer Protection, Economics and the Offices of Policy Planning and Technology. The effort implements President Trump’s February 2025 executive order to boost competition,...

Healio’s latest editorial highlights the expanding role of GLP‑1 receptor agonists in immune‑mediated inflammatory diseases, emphasizing weight‑independent anti‑inflammatory mechanisms. Emerging data suggest central nervous system GLP‑1 activation can modulate peripheral immunity, linking the gut‑brain‑immune axis. The FDA’s recent approval of...

Xeruborbactam (QPX‑7728) is a broad‑spectrum β‑lactamase inhibitor designed to revive the activity of β‑lactam antibiotics against multidrug‑resistant Gram‑negative bacteria. Developed by Qpex Biopharma and Shionogi, the molecule targets both serine‑ and metallo‑β‑lactamases, addressing a key resistance mechanism. Preclinical data show...

The FDA will convene a March 27 public meeting to revisit the DSHEA “innovation door,” specifically the phrase “dietary substance for use by man to supplement the diet by increasing the total dietary intake.” Industry leaders from the Natural Products Association,...

Jodi Bigness, hospice manager at Partners in Care, has been named to the Frontline Honors Awards Class of 2025, recognizing her dedication to patient‑centered hospice care. In a recent Hospice News interview, she debunks common misconceptions about hospice, emphasizing comfort,...

One of the biggest fears about healthcare's AI revolution is that AI can erode physicians’ expertise and their performance may drop when AI is removed. A new scoping review provides examples for that. In colonoscopy, the adenoma detection rate dropped significantly...

Is healthcare actually a market? According to Chris Klomp, RFK's No. 2 at HHS, the answer is: Not yet. I sat down with Chris and Jon Gordon to discuss how we turn technology into a "deflationary force" instead of a cost-adder. The...

The U.S. Supreme Court denied Takeda Pharmaceutical and Eli Lilly’s request to block a racketeering lawsuit, allowing a class action alleging the companies concealed Actos’s link to bladder cancer to proceed. The suit targets tens of thousands of insurers and other...

Rural hospitals, already strained by shrinking Medicaid enrollment and decades of closures, now face an acute threat: 315 facilities are at immediate risk of shutting down and another 450 are in serious jeopardy. A core driver of this crisis is...

A new prenatal therapy combining in‑utero surgery with placental stem‑cell patches, tested in the CuRe trial, has shown promising safety results for spina bifida. Six pregnancies underwent the procedure between 19 and 26 weeks, all delivering without infection, fluid leak,...
Integrated DNA Technologies (IDT) announced the launch of two in‑vitro diagnostic kits, Archer FUSION Plex‑HT Dx and VARIANT Plex‑HT Dx, marking its entry into the next‑generation sequencing (NGS) IVD market. Built on IDT’s proprietary anchored multiplex PCR chemistry, the kits offer targeted DNA and RNA...

GE HealthCare obtained FDA 510(k) clearance for Photonova Spectra, its photon‑counting CT system. The scanner uses Deep Silicon detectors with 8‑bin energy resolution, delivering simultaneous spectral and high‑definition images in a 0.23‑second rotation. NVIDIA GPU‑accelerated reconstruction handles the 50‑fold data...
The article argues that drug pricing debates must focus on aligning prices with the full value medicines deliver to patients and society. It critiques current health technology assessment (HTA) practices for using narrow benefit definitions, which can depress prices and...

MLB The Show 26, Sony’s flagship baseball simulation, is being repurposed as a digital‑health tool to gamify physical and cognitive rehabilitation. By embedding reward systems, progress tracking, and multiplayer interaction, the game transforms repetitive therapy into an engaging experience. Therapists...

Patient monitoring systems must align alert methods with room dynamics. In quiet patient rooms, discreet solutions such as pressure‑sensitive pads, low‑volume local alarms, pager alerts, and nurse‑call integration minimize disturbance while still notifying staff. High‑traffic wards require louder audible alarms,...
A population‑based study of 148 first‑line CLL/SLL patients in Alberta found that time‑limited venetoclax‑obinutuzumab was used in 51% of cases, while continuous BTK inhibitor therapy accounted for 44%. Patients with del(17p) or TP53 mutations chose BTK inhibitors in 84% of...

A National Academies report finds no clinical guidance exists for treating long‑term health effects of JP‑5 jet fuel exposure, which contaminated drinking water for roughly 93,000 residents and service members in Hawaii in 2021. The study documents limited, suggestive evidence...

Samsung Medison announced that its two U.S. imaging units, Neurologica and Boston Imaging, will merge under the new corporate identity Samsung HME America. The consolidation brings together ultrasound, digital radiography and CT operations into a single, globally‑branded organization. Samsung says...

Theranica’s Nerivio, a remote electrical neuromodulation (REN) device, has secured nationwide coverage for roughly 130 million lives through Blue Cross Blue Shield plans. The therapy’s dual acute and preventive indications offer a drug‑free alternative that expands access to underserved groups such...
United Health Services completed the acquisition of virtual behavioral health platform Talkspace at $5.25 per share, valuing the company at roughly $835 million enterprise value. The purchase brings about 6,000 licensed clinicians into UHS’s network, directly addressing chronic staffing shortages and...

University of Exeter researchers have launched a study to determine whether people living with acquired brain injury (ABI) employ social camouflaging strategies. Led by MSc student Faye Brookes and Associate Professor Anna Adlam, the project will use a 20‑30 minute...

PromptWell and Ellipsis Health have announced a partnership that merges PromptWell’s AI‑driven timing engine with Ellipsis Health’s emotionally intelligent voice agent, Sage. The combined platform predicts the exact moment a patient is most likely to answer and then engages them...

The ongoing Iran‑Israel conflict has not yet crippled global pharmaceutical supply chains, but it threatens the modest 0.3% of worldwide drug output and 0.6% of active‑pharmaceutical‑ingredient (API) production that originates in the region. Disruptions to key shipping lanes, especially the...
The $PFE/ $VALN Lyme vaccine was a product for which there was a lot of hope. Results today show OK efficacy. Vaccine efficacy landed at 70%; investors hoped for 80% but thought as low as 60% would be relevant. But the...

Another win for Dizal, but how do US patients get hold of Zegfrovy? Via @ApexOnco -> https://t.co/4GVjyHS9vz https://t.co/bjjrnZkNL6

Patient dissatisfaction is driving a surge in DIY health hacks, especially in gastroenterology where one‑third of patients report avoiding care after negative experiences. Influencers promote trends like "fibermaxxing," urging excessive fiber intake that can aggravate conditions such as small intestinal...
Another day, another acquisition by drug wholesaler monopolist Cencora. This one is EyeSouth Partners's retina business for $1.1 billion. https://t.co/F6Cj1hXCzy
A thrill to be on @CBSMornings today talking AI and Healthcare (and about my book, "A Giant Leap") with @nateburleson & @DrLaPook. Interview is here: https://t.co/YJygJk0qh8

CMS Administrator Dr. Mehmet Oz warned Maine that Medicaid fraud will no longer be tolerated after reports that Paradise Residential Services billed over $16 million in inflated rates, charging twice the national average for autism residential care. The provider, accused of...
FDA seeks feedback on voucher program; Study data lift ‘overhang’ on Insmed shares https://t.co/BCRJAUwGIJ $INSM + 7% $SRPT $SNY $GSK #biotech
The data is finally catching up: $600B+ opportunity by 2030. Women’s health remains one of the most asymmetric opportunities in healthcare—where the next generation of category-defining companies like @mavenclinic will be built. https://t.co/K9nUGweSDK
A Maryland‑wide predictive model using Medicare fee‑for‑service claims and publicly available social‑determinant data generated risk scores for 346,614 beneficiaries, released on June 7 2024. The model retained 95 statistically significant factors out of 219 candidates and produced a mean score of 0.0124,...
As someone who lived in Vermont and still spends the summer there, it's disappointing to see the ambiguity in Pfizer's data on a new Lyme disease vaccine. It's a serious threat. Now we can move on to speculating on the...
I've been saying this for the longest time, and including fecal pH in my grant applications, too I predict that we'll see a significant correlation for fecal pH with neurodegenerative diseases in future papers...

Pharmaceutical manufacturers are re‑examining traditional PBM‑centric distribution by offering direct‑to‑employer drug purchasing models. Companies like Andel charge a per‑prescription transaction fee and eliminate administrative or per‑member fees, aiming to lower drug spend for employers. Their platform centralizes prescription intake, routes...
Paradox: The FDA approved some fecal transplants for C. difficile. But accessing treatment got harder. https://t.co/AFFyCGPeKW
The news is mixed in the preliminary results from a Phase 3 trial of a needed #Lyme disease vaccine, @matthewherper reports. https://t.co/bcbfeXchk1

Researchers published a meta‑analysis of 19 randomized trials showing that topical diclofenac gel significantly reduces the incidence of grade 2 or higher chemotherapy‑induced hand‑foot syndrome, especially in patients receiving capecitabine. The analysis also identified topical silymarin, pyridoxine 400 mg, and celecoxib as...
"Over the past year, the U.S. has added 156,000 jobs—but healthcare alone was responsible for 375,000 new jobs." https://t.co/85IevT4vGd

Somerset Indus Capital Partners announced the closing of its third fund with $288 million in commitments, surpassing the $250 million target. The fund, backed by development finance institutions, global investors and family offices across Europe, the U.S. and Southeast Asia, will target...
Her son needed a fecal transplant for a fearsome C. diff infection. Getting one required a tortuous journey https://t.co/Ln54u1iTPV via @statnews

Carefam, a conversational AI platform for healthcare staffing, emerged from stealth with a $14.5 million Series A led by Pitango HealthTech and backed by Emerge. The solution automates candidate outreach, interview scheduling, and credential verification, escalating only complex decisions to human HR...

A new retrospective cohort study of over 3 million commercially insured U.S. adults found that COVID‑19 infection dramatically increases the risk of kidney complications compared with influenza. Adjusted hazard ratios show nearly double the risk of any kidney disease (HR 1.93), a...

Guideline Update Provides New Testing & Tx Recx for Pts w/ ER-Positive, HER2-Negative Met Breast Cancer w/ ESR1 Mutations [May 17-18, 2023] @ASCO Daily News - https://t.co/3ZVrEkQEN5 @DrHBurstein et al. @JCO_ASCO https://t.co/68e7D0CSgU #bcsm #PrecisionMedicine #LiquidBiopsy https://t.co/KBx2hq2BDW

Lenalidomide + high-dose dexamethasone (RD) vs lenalidomide + low-dose dexamethasone (Rd) as initial therapy for newly diagnosed multiple myeloma: an open-label RCT [10/22/2009] @VincentRK et al. @TheLancetOncol https://t.co/hXxlFINejC #NCT00098475 #EAonc E4A03 #mmsm #caxtx #ctsm https://t.co/3Pa2TRMntk

Medicare Part B premiums jumped to $202.90 a month in 2026, the first time they have cleared the $200 threshold. The Social Security cost‑of‑living adjustment added $56 to the average benefit, leaving retirees with a net gain of only about $38...