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Impulsivity in ADHD
Impulsivity in ADHD stems from an imbalance of dopamine and serotonin, leaving the brain unable to regulate the “go” and “stop” signals that govern behavior. Research shows that low dopamine receptor activity and reduced serotonin receptors amplify impulsive actions, from spur‑of‑the‑moment decisions to risky spending. Regular aerobic exercise and reflective self‑inventories have been proven to dampen these symptoms, while structured strategies such as cooling‑off periods add friction to impulsive choices. By channeling the heightened drive into fast‑paced hobbies, individuals can turn a liability into a productivity asset.
Pfizer, Arvinas Win FDA Nod for VEPPANU, First PROTAC Cancer Drug
Pfizer and Arvinas have secured U.S. FDA approval for VEPPANU (vepdegestrant), the first orally bioavailable PROTAC drug, targeting estrogen‑receptor positive, HER2‑negative, ESR1‑mutated advanced breast cancer after endocrine therapy failure. The decision validates the targeted protein degradation platform while raising questions...
Mitochondrial Health Drives Egg Quality and Fertility
The largest cell in your body is your egg. It is one of the only cells you can see with the naked eye. It also contains more mitochondria than any other cell in your body. Hundreds of thousands per egg compared...
Seeking Perspective: Tetons Reveal Distant Horizons
Heading to the Tetons today to look at things that are very, very far away from me.
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15 Stunning U.S. Mountain Ranges Perfect for Your Next Adventure
The article highlights 15 of America’s most iconic mountain ranges, from the mist‑shrouded Great Smoky Mountains to the volcanic Cascades and the towering Alaska Range. It details each range’s signature attractions—national parks, scenic drives, historic railways, and world‑class ski resorts—showing...
Daily Stillness Shields Against Stress‑Driven Decisions
Going into the day without sitting in at least a min or two of stillness makes us susceptible to making stress-based decisions and to being more reactive than responsive. Since stress isn’t taking any days off, we ideally don’t wanna...
Scientists Just Discovered What Coffee Is Really Doing to Your Gut and Brain
Researchers at APC Microbiome Ireland, part of University College Cork, published a Nature Communications study showing that both caffeinated and decaffeinated coffee reshape the gut microbiome and positively affect mood. The trial compared 31 regular coffee drinkers with 31 non‑drinkers,...
Testing SkiErg Gains on Upcoming Running Build‑Up
Almost back to running. A nice easy build up during May is planned. Strength fairly decent. Interested to see if all this SkiErg translates across to running fitness (probably negligible and I’ll be absolutely gasping after 2 mins at 06:00...
My Dream Google Chrome Extension Didn't Exist, so I Vibe Coded It with Claude
A developer built a Chrome extension called “Pomodoro Tab” that goes beyond a simple timer by adding selectable focus levels and a Hard Mode that locks the active tab during work sessions. The core features—Pomodoro countdown, focus‑level toggle, and tab‑locking...
430. METHYLENE BLUE PART II: ANTIBACTERIAL, ANTI-LYME, AND ANTI-VIRAL EFFECTS
This episode dives deep into methylene blue (MB), exploring its historic roots and its emerging role as a broad-spectrum antimicrobial, antiviral, and antiparasitic agent, especially for persistent tick‑borne infections like Lyme disease and Bartonella. The host explains MB’s mechanisms—disrupting bacterial...
Loquats: Underrated Fruit Tree with Citrus‑Peach Flavor
I’ve grown loquats for over ten years and am always surprised how unknown they are as a fruit tree… They produce hundreds of yellowish-orange fruits per year that taste like a tropical citrus peach Great for fresh eating, but I’ve also...
Spring in Cefalù: History, Gelato, and Yacht Views
Enjoyed the perfect spring day in the little Sicilian town of Cefalù, about an hour from the capital Palermo. Like so much of Sicily, it has influences of the conquerors -- Romans, Byzantine, Arabs and Normans. Now it's a major...
Billions of Beetles Blanket the Coastlines of Scotland
A massive surge of heather beetles has blanketed Scotland's Caithness coastline, with billions of dead insects washing ashore. The beetles' larvae inject enzymes that kill heather, turning the iconic purple moorland into dry, brown “ghost heather.” This vegetation loss heightens...
Filters Can't Add Light; They only Attenuate Spectra
Do we think this is real? I’m struggling to see how a filter can *add* or enhance light in a certain spectrum because filters can only - by definition - filter light *out*. What am I missing?
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9 Ways to Cope With Work Stress and Avoid Burnout
The article presents nine actionable tactics for coping with work‑related stress and averting burnout, ranging from a pre‑work ritual and clear daily expectations to organized workspaces, chunking tasks, and music breaks. It highlights the serious health risks of chronic stress,...
First Look: Michael Jordan’s Classic Air Jordan 3 Is Getting an Ultra-Premium Upgrade
Nike is releasing an ultra‑premium version of the iconic Air Jordan 3 as part of its revived Bin 23 collection. The sneaker features a new Team Red/Metallic Gold/Burgundy colorway and combines leather, nubuck, suede and gold hardware, with a pre‑yellowed midsole and waxed‑inspired tongue...
Boston Globe Deletes Two Hostile BSO Quotes
The Boston Globe’s latest print edition omitted two anonymous, critical quotes about the Boston Symphony Orchestra that had appeared online. One quote came from a board advisor questioning the accusatory tone of an internal memo, and the other from a...
Self‑Funded Vision Pays Off After Years of Obsession
Fun and inspiring listen about a filmmaker haunted by an idea for years, putting his own money on the line to make it happen—and winning.
Review Flags Neurotoxic Risks of Silver Nanoparticles in Rodent Studies
Researchers from Çanakkale Onsekiz Mart University and University Montpellier published a review on 29 April 2026 that links silver nanoparticle exposure to multiple neurotoxic mechanisms in rodent models. The paper warns that expanding biomedical applications—such as neural implants and drug‑delivery systems—must contend...
Correcting Weight Misinformation Aligns with Neutral Care
If you see me correcting weight loss or metabolic misinformation on here, it doesn't negate my weight-neutral perspective or approach to care. Misinformation about weight & metabolism causes real harm. It sends people chasing solutions that don't work, and then blaming...
SpaceX Lifts Off 45 Satellites on Nighttime Falcon 9 From Vandenberg
SpaceX launched 45 satellites on a pre‑dawn Falcon 9 from Vandenberg Space Force Base on May 3, 2026. The mission carried South Korea's CAS500-2 Earth‑observation satellite as its primary payload, marking a rare nighttime deployment for the company and expanding...
Drop the Crab Mentality, Unlock Humanity’s Prosperity
The moment we lose that crab in the barrel mentality, we will prosper as a human race.
Loyal's Canine Longevity Pill Nears Market After FDA Deems Likely Effective
Loyal, the biotech startup founded by Celine Halioua, has moved its canine longevity pill closer to market after the FDA deemed it likely effective in February 2025. The drug, which could add a year to a dog’s healthy lifespan, arrives amid...
'Michael' Box Office: The King of Pop Moonwalks Past the King of Rock and Roll
The Michael biopic posted a $54 million second‑weekend, a 44% decline from its $97 million opening, bringing its ten‑day domestic total to $184 million. Its 3.75× weekend multiplier signals strong all‑ages appeal, outpacing the second‑weekend holds of Elvis (‑41%) and Bohemian Rhapsody (‑37%)....
The Spiritual Personality Trait Linked To Happiness (M)
Recent research identifies a distinct spiritual personality trait that consistently correlates with higher happiness levels. Individuals scoring high on this trait report greater hopefulness and a more positive appraisal of their life circumstances. The study, conducted by psychologist Dr. Jeremy...
The Real Work Starts After a Mental Health Crisis
Emergency physician Dr. Kenneth Scott Burnham recounts his own descent into mental‑health crisis after 23 years of stabilizing patients in the ER. He describes the stark contrast between acute crisis care and the unsupported, confusing period that follows discharge. Burnham...
Small Daily Habits Compound Into Lifelong Longevity
As a scientist studying aging, I can’t stress this enough: You don’t need to optimise everything. What really moves the needle is the compounding effect of small habits repeated over years. The 20-minute daily walks. The nutrient-dense, fibre-rich breakfast bowl...
Academy Bars AI‑Generated Actors and Scripts From Oscar Eligibility
The Academy of Motion Picture Arts and Sciences announced that AI‑created performers and chatbot‑written scripts will be ineligible for Oscar awards. The rule requires that credited roles be performed by living humans with consent and that screenplays be human‑authored, a...
Screens Can Be Part of a Child's Healthy Bedtime Routine, Study Shows
A new meta‑analysis by Deakin Institute and the University of Queensland examined 4,562 participants aged three to 25 across 25 studies. It found that daily screen use before bed may delay bedtime slightly but does not significantly affect total sleep...
'It Was Quite a Light Show!' NASA Astronaut Spies Dramatic Fireball From the International Space Station (Photos)
NASA astronaut Chris Williams photographed a bright fireball from the International Space Station cupola on April 27, 2026 while the station passed over West Africa. The streak, which split into multiple fragments, is believed to be the re‑entry of debris from the Progress MS‑34...
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Can You Take Benadryl While Breastfeeding? What Parents Need To Know
Benadryl (diphenhydramine) is a first‑generation antihistamine that can enter breast milk, potentially making a nursing infant drowsy or irritable. Health professionals advise limiting its use to emergencies because regular dosing may also lower the parent’s milk supply and impair coordination....
Embassy of the Free Mind / Easy Search on Phone / Free Wireless Speaker
A recent roundup highlights several niche cultural and tech resources. The Embassy of the Free Mind in Amsterdam has digitized thousands of rare occult manuscripts, making them freely searchable online. Android users can now use Google’s Circle to Search to...
Prada 2 Delivers $233M Global Opening, M
BOX OFFICE: Prada sequel struts to a $77M opening (domestic) and a massive $233M worldwide. Some stats: - 2nd biggest global opening of 2026 - Biggest opening ever for Meryl Streep - Prada 2 took in over 70% of the original film’s total...
Wytchwound Pulls Us Under Her Spell with Eponymous EP
Scottish singer‑songwriter Eve has launched her new project Wytchwound with a self‑titled EP that fuses dark grunge, folk and gothic tones. The six‑track record draws on the 17th‑century Fife witch trials, giving the condemned women a modern voice through haunting...
Physics‑Driven Resorbable Sensors Enable Flow‑Following Environmental Monitoring
As a follow-up to our recent Comment article in Nature Communications (https://t.co/iw17gRHNBJ) and our original paper in Nature (https://t.co/CPajKHsld5) on environmental monitoring using tiny, eco-resorbable wind/water dispersed wireless sensors, we just published a Perspective piece in the new journal APL...
A Fearless Activist and a Rebel for Her Time
Clare Paterson’s new biography, *The Nine Lives of Annie Besant*, chronicles the life of the British‑born activist who became the first woman president of the Indian National Congress in 1917 and a leading figure in the Theosophical Society. The book traces...
Argue with an Aim
The post "Argue with an Aim" revisits the ancient roots of argument—from Greek rhetoric and the Socratic method to Aristotle’s logic—asserting that its true purpose is truth‑seeking, not ego‑driven victory. It highlights how modern debates often devolve into self‑serving posturing...
Family Offices Add Wellness Services for Next‑Gen Principals
Folks constantly ask me, what do I do? What is a family office chief wellness officer (CWO)? I help family offices add health, wellness, longevity, and lifestyle design services into their offerings. Modern principals, particularly the next-gen, want their family offices...
Focus, Optimize, Write: Indie Author Weekly Sprint
Try to do these 3 things this week as an indie author: 1. Push one book—hard. Stop trying to market everything. Pick your strongest entry point and drive traffic there. - ads, trial reels, social media posts etc Does this move that...
Full Trailer for 'Knight Rider: Declassified' Geeky 80s Throwback Doc
A five‑part, five‑hour documentary titled *Knight Rider: Declassified* is set to debut, offering never‑before‑seen interviews with the original cast, creators, and crew of the 1980s TV hit. Produced by Richard Grant Bennett and Rocco DeVilliers, the series was filmed in...
20-25% of 1976 Bands Still Touring After 50 Years
From summer 1976 Amazing that 20% - 25% are still touring in some form 50 years later https://t.co/R19XzUrEDS
Kids Are Joy; You Can Balance Family and Career
I had three kids under 24 months when I founded @boomsupersonic. And I didn’t have a supportive partner. Kids are a joy not a burden—even under difficult circumstances. You can have a family and an ambitious career—particularly if you choose your...
Graduation Day Is a Strange 80s Slasher Worth Watching on Tubi
Graduation Day, a 1981 low‑budget slasher directed by Herb Freed, has resurfaced as a cult oddity thanks to a new 4K restoration of its original 35 mm print. The film’s bizarre plot—featuring a stopwatch‑wielding killer and a Navy‑officer heroine—sets it apart...
Calm Politeness Amid Conflict Is a Superpower
The ability to stay calm and polite, even when people upset you, is a superpower.
Deep Learning Unlocks Untapped Prevent
Latest @EricTopol https://t.co/cPXyNN0DOe (v.i.) highlights DL-enabled oppys to gather additional health insights from imaging medical establishment isn't taking advantage of. Thru dif lens, describes meaningful preventive hlth oppy for entreps. @DanielSodickson @NathanPriceSci https://t.co/UC5Sgn6WR4
Daily Prebiotics & Probiotics Protect Gut and Health
How many prebiotics and probiotics are you consuming each day? They help keep your gut microbiome healthy with a thick mucosal lining and tight junctures that help prevent leaky gut, inflammation, and many chronic conditions. Nourish your body. #Health #Healthy #lifestyle https://t.co/8SIpj8fuuq
China's IMAX Boosts The Devil Wears Prada 2 to $550K
One place where fans CAN see #TheDevilWearsPrada2 on IMAX scrns? CHINA Film did $550k there this wknd from its IMAX scrns, $8.5M total from all scrns in the mkt. https://t.co/ySWghASDYi
Sodium's Performance Boost: Limited Evidence Beyond Hydration
Sodium is often promoted as a performance enhancer, but what does the evidence say? This blog reviews the limited research on sodium intake during exercise and questions whether it improves performance beyond supporting hydration. Click here: https://t.co/ekABuKBMDR https://t.co/B5SZbA1psH
You Can Achieve More, Faster than You Think
"People underestimate themselves and overestimate how long things take. You can do far more than you think, far better, and far faster." via @farnamstreet
Second Half of Non-Awakening Series Now Free
So they dropped the second half of my non-awakening series on the Waking Up app. You get 30 days free to check it out. link in reply https://t.co/EWr9vdTfZp