Singaporeans Increasingly Aware of Healthspan and Longevity Medicine
Knowledge of lifespan and healthspan and interest in Healthy Longevity Medicine among the general population in Singapore: the Singapore HEalthy LOngevity (HELO) survey https://t.co/urqgBWfzIW https://t.co/y6skIWdASG
Targeted mRNA Nanoparticles Halt Lung Tumors and Cachexia
Follistatin mRNA delivered via targeted lipid nanoparticles enables a dual therapeutic effect by simultaneously suppressing lung tumor growth and preventing cancer-associated muscle wasting (cachexia). https://t.co/56fCFZU0vk
Digital Math Gains Don't Translate to Paper Skills
Is fascinating watching our 5yo learn math from an iPad app, just shockingly quickly. But then also not be able to reproduce any of the concepts on paper 😅 Will keep iterating to figure out how to get concepts to transfer...
Slow Down to Speed Up.
The best advice I've ever received: Slow is smooth and smooth is fast. Lesson: Slow down to speed up.
Kindergarten Prep Leaves Parents Overwhelmed and Emotional
My husband and I went through my sons kindergarten information and I’m already crying lol I’m gonna be a mess in August
Claude Lalanne Mirrors for Y
If you're in New York or can be, run to see the mirrors that Claude Lalanne made for Yves Saint Laurent and Pierre Berger, on display now at Sotheby's Breuer for $15m as part of the Gunzberg sale.
Aging Opens Chromatin, Altering Cell Behavior
The researchers then looked into the changes in the old cells that might explain such pronounced differences in behavior compared with the young cells. Liao Says "It seems as though chromatin opens up with age, so to speak." https://t.co/1kdRDunTea
Space Isolation Overcome: Lessons From Polar Pioneers
An astronaut's antidote to despair (with help from early polar explorers, the astronauts of the prior century) https://t.co/ag0U9xOxOx
Value Efficiency over Busyness: Work Smarter, Rest More
We need to stop glorifying "being busy". Let's glorify: • Doing less but better • Protecting your energy • Resting before burnout • Deep work over long hours • Saying no to bad meetings • Finishing early because you were efficient
Sexist Book Covers Could Rekindle Young Men's
@robkhenderson Mildly sexist thought for the day. If we want to get young men reading again, we should make book covers look like this again. https://t.co/df1W3xhqKH
Bravery Is the Next Step, Not a Setback
You are not behind. You are at the part where you have to be brave on purpose.
Constraints Spark Creativity, Not Block It
Constraints don’t block creativity, they cause it. For a deep dive on how constraints can you more creative, productive, and satisfied, check out my new book, INSIDE THE BOX. Link in my bio. https://t.co/WoLT32w5Rv
Home Gym Costs 80% Less, Near Commercial Quality
6 weeks ago I shared that I was building a home gym… it’s officially done… around 12 pieces of equipment if you include the treadmill and punching bag (which I filled up last night)… obviously the smith machine with cables...
Start Now, Embrace Imperfection, Celebrate Small Wins
Don’t get stuck in the idea stage. Perfect plans don’t exist. Believe in yourself more. Begin before you feel ready. Aim for small victories. Just keep the momentum going.
Annealing Boosts Efficiency of Copper-Plated Heterojunction Cells
The impact of annealing on copper-plated heterojunction solar cells #energysky -- via pv magazine global: https://t.co/DM37J5KaRF https://t.co/POFNPoUMby
Front Squats Maximize Quad Development and Upright Mechanics
Front squats are one of the best squat variations for building strong quads, a rock-solid trunk, and cleaner overall squat mechanics. Because the bar sits up front, they force a more upright torso and hit the knee extensors (quads) harder than...
Best Box Office Quarter
Box office buzz: Best quarter in five years fuels hopes for Hollywood comeback @seekingalpha The full round-up from us at @wallsthorizon by @christinelshort https://t.co/ngUwIEjPh2 https://t.co/ct8xRTD35h
Forgot Our Suitcases Hours Before 5‑Week Trip
We leave for a 5 week international trip in 24 hours…. And just pulled out our suitcases 🤦🏻♂️
Aviation‑Inspired Carbon Fiber Watch Redefines Performance
The Daytona Avia Grey by @diw_official reinterprets performance through the language of aviation and advanced materials. Its high-end carbon fiber case reveals a layered structure where every line is driven by engineering rather than ornament. #DiW #DesignaIndividualWatches #DiWOfficial #WatchCollector #HauteHorlogerie
More Isn't Better—Prioritize Health Over Social Metrics
It’s not always about more. Social media can make this hard to grasp as it always seems like someone else is ahead by doing more. More isn’t always better. Your long term health means more than anything on Strava or...
Google Backs Immersive Eyewear Brand Gentle Monster's Retail Revolution
Big fan of Google’s $100m investment in Gentle Monster to do smart glsses. Been to a few of its stores and layouts are slick. The South Korean lux eyewear brand does ~$600m a year. Retail setups have dope sculptures and 3D...
Give Your Body What It Needs, Period Returns Naturally
Things I did to get my period back after 16 years: - Gained 25 pounds on purpose - Stopped running - Ate 2,500+ calories a day - Added carbs back - 7-8 hours of sleep - Reduced my exercise intensity (temporarily) - Stopped fasting - Worked on...
Indie Comedy Delivers Back‑to‑Future Fun, Surprises Critics
Watched this last night. Very good, like an indie comedy version of Back to the Future. It sucks you into its crazy world. Great characters you enjoy hanging out with. Pleasantly surprised bc previews looked dumb, altho it did get...
2026 Box Office: Chinese Pegasus3 Leads US Blockbusters
Global #BoxOffice Top10 2026 releases ONLY #Pegasus3🇨🇳$646.3M #TheSuperMarioGalaxyMovie 🇺🇸 $628.8M #ProjectHailMary 🇺🇸 $510.7M #HOPPERS🇺🇸$354.4M #WutheringHeights 🇺🇸$241.4M #BladesOfTheGuardians🇨🇳$214M #Scream7🇺🇸$212M #ScareOut🇨🇳$198.5M #GOAT🇺🇸$186.2M #Dhurandhar2 🇮🇳$184.6M https://t.co/k4TNJvuMTl
Bieber’s Vulnerable Moment Shows Courage in Spontaneous Connection
Justin Bieber giving the audience a voice felt spontaneous & lo-fi. But also took real courage. It could’ve gone horribly, embarrassingly wrong. We could be having a different conversation about him. It resonated because of the collective nostalgia (his & ours)...
Discover Ever-Present, Unlimited Peace Through Awareness
Rupert’s audiobooks are now available to listen anywhere. An invitation to explore awareness, not as an idea, but as your direct experience. “As we become aware of being aware, we come to recognise that awareness is ever-present, unlimited and inherently peaceful.” https://t.co/KGwcg0dKmO
No Hollywood Remake of 1984 yet, Despite Star Power
I can’t believe there hasn’t yet been a big splashy Hollywood remake of 1984 starring, like, Timothée Chalamet and Sydney Sweeney.
Artemis Highlights NASA’s Evolving Mission Landscape
This post is now a newsletter, with hyperlinked sources + some thoughts on Artemis and the state of NASA https://ayanaelizabeth.substack.com/p/earth-is-blue-thank-you-artemis
Saying No Enables Flow and Focus
You can do anything, but you can’t do everything. You must say no in order to flow.
Personal Awareness Defines True Meta‑consciousness
If awareness is not personal, what does it truly mean to be aware of being aware? Watch Rupert’s latest video here on YouTube: https://t.co/nsJ7SxLqUg https://t.co/o34x3TP0U6
New Hunger Games Poster Revealed, Trailer Arrives Tomorrow
New poster for THE HUNGER GAMES: SUNRISE ON THE REAPING. Trailer drops tomorrow. Stars Joseph Zada, Jesse Plemons, Ralph Fiennes, Glenn Close, Kieran Culkin, Elle Fanning, Mckenna Grace, Maya Hawke, Whitney Peak, Kelvin Harrison Jr. #TheHungerGames @Lionsgate https://t.co/cJJf9JmSOi
IPSC Therapies Succeed; In‑vivo Reprogramming Remains Hype
your regular reminder that Yamanaka factor-driven production of iPSCs is already producing real medicine (eg dopaminergic neural progenitor for Parkinson's, cardiomyocyte sheets for heart failure & more) iPSC tech is not done in vivo... ppl isolate the well behaved cells away...
Daily Evoked Gamma Therapy Shows Safety and Cognitive Benefit
Safety, tolerability, and efficacy estimate of evoked gamma oscillation in mild to moderate Alzheimer’s disease 👉 “Our results demonstrate that 1-h daily treatment with [CogTx-001] was safe and well-tolerated and demonstrated potential clinical benefits in mild to moderate AD.” 🔘 Participants underwent...
Taper Week: Rest, Not Fitness Gains, Is Key
If you’re tapering for your race now, here are a few things that might be helpful to hear. Zoom out from this week for a second. Your body is responding to months of training. Do not go into any of...
Three Simple Weekly Tasks to Boost Indie Writing
Try to do these 3 things this week as an indie author: 1. Use your strongest performing trial reel and post it every day this week, with the same description, diff music, vary the length, use 1+ stickers, and change the...
Modest $8M Opening Keeps $18M Film Viable
The Will Packer-produced 'You, Me & Tuscany' opened with $8 million, an underwhelming figure but not a disaster for an $18 million flick that ran into unexpected genre competition.
Imagine Your True Self Without Others' Opinions
Thought experiment: Who would you be if for even a moment you released and were completely free from the concerns and opinions of others?
Relationships Need Maintenance, Not Repair Like a Car
As a couple’s counselor, do you know what I have to constantly emphasize? Your partnership is no a car, so Maintenance ≠ Repair
Final Edits Done, Sunset River Reflections Seal Progress
Down to the last 15 pages of the first round of copy edits for my first book. Chose to review it by the river at sunset.
Daily Learning Invests in Your Future Self
Learning is a daily investment in your future self. Each new insight expands your capacity.
Uta Frith: Autism Isn't a Spectrum
There is no autism spectrum, says expert (esteemed cognitive scientist Uta Frith) who pioneered our understanding of the cognitive deficits underlying autism. https://t.co/a5e8jZzUbF
Make the Overwhelming Feel Routine
When I was in HS I used to eat a full dinner—steak, chocolate milk, you name it—and then head right out the door for 9 miles at 6min pace It sucked for a week, then your body adapted & it was...
Progressing Fast: Seasonal Training Boosts Race Speed
Short-course season progressing well Idea was to take the pressure off my training and focus on improving swimming (winter) then bike top end (spring), then bike tempo (summer) Cocoa Beach Tri this morning, 1-2-3 less than a minute apart. 2nd for me Each...
Beavis & Butt‑Head Movie Succeeds by Breaking TV Format
The smartest-ever movie version of a TV show was Beavis and Butt-Head Do America, because it built its plot on shattering the structure of the show – they took away their television and forced them to leave the house
Hidden Nutrient Depletion Threatens Women Trying to Conceive
Things that deplete your nutrient stores that nobody warns you about: - Birth control (zinc, magnesium, B2, B6, B12, folate, vitamin C, vitamin E) - PPIs for reflux (B12, magnesium, iron, zinc) - Metformin for PCOS (B12) - Undereating for years - Pregnancy - Breastfeeding - High...
Box Office Down 16% as New Hits Rise
WKND #BoxOffice Chart ▶️ #SuperMarioGalaxy still has high score ▶️ #ProjectHailMary cracks $250M ▶️ #YouMeAndTuscany debuts in 4th Top 10 at $120.7M, down 16% from last year when Minecraft held #1 spot. See full wknd chart at: https://t.co/H9rtcx7IlP.
Only Books that Boost Results Truly Improve Sales
Most sales books sound great in theory. But only a few actually change how you sell every day. The real test is simple: did it improve your results? Comment below the sales book that changed how you sell. https://t.co/XP6GT41RoQ
Health Is a Holistic Balance of Mind, Body, Spirit
How I define health: • Mind, body, spirit • Low resting heart rate • Consistent energy levels • Body I feel proud to see in the mirror • Progressively improving strength levels • Body with relatively few aches and pains • Low levels of intrusive thoughts or...
Work Thoughts Won’t Stop After 24‑Hour Break
I used to say that I needed 24 hour breaks from work. So I can take a day off on the weekend and work the other day. But recently it takes me about 24 hours just to stop myself from...
Arthurian Legends: Mostly Myth, Not Medieval History
Picked up this book thinking I would learn about King Arthur, and perhaps pick up a little about British history. But a third of the way through, I'm learning that historians agree that it's almost completely made up, the 1100s...