Moderna Launches mRNA Hantavirus Vaccine Development in 2024
Did ya know… Moderna began working on an mRNA vaccine for hantavirus in 2024. $MRNA
AI‑enhanced Dog Breath Test Detects Cancers with 90%+ Accuracy
New MCED / cancer screening test: Dogs smell human breathing + Bayesian AI detects multiple cancers with 90.8% sensitivity & 91.3% specificity (AUC 0.962), even in early stages. Phase II India study (1,502 people, 7 cancer types)- strong potential for affordable...
IGF‑1 Switch Drives Biphasic SASP Aging Model
The IGF-1 senescence switch: a biphasic model for SASP-driven aging and precision senomodulation https://t.co/f0BoHbaeCK? https://t.co/NjDlT0O9hQ
T‑Doped Clifford Circuits Efficiently Approximate Unitary K‑Designs
Recent years have enjoyed a strong interest in exploring properties and applications of random quantum circuits. In this work, we explore the ensemble of 𝑡-doped Clifford circuits on 𝑛 qubits, consisting of Clifford circuits interspersed with 𝑡 single-qubit non-Clifford gates. We establish rigorous convergence bounds...
Rare Andes Virus Surfaces on Dutch Cruise, Still Limited Cases
Now back to reality. The Andes Virus was discovered in Argentina in 1995. There have been only around 2000 documented cases in South America in 20 years. That virus wasn't a thing until 8 cases were discovered recently on that...
A Decade Later, Climate Spiral Still Shocks
Spiralling global temperatures (1850-2026) It is exactly 10 years since I first put this animated graphic of changes in global temperature online. #ClimateSpiral It instantly went viral. People watched it over and over again. It still offers the power to shock a decade...
Dual‑LAO Accelerates Robust Binding Free Energy Calculations
New paper published @CommsChem with the @qubit_pharma team led by @Narjes_Ansari: "Dual-LAO for calculating fast and robust relative binding free energies of simple and complex transformations" (#OpenAccess) #compchem #drugdesign @FefeAviat J. Hénin L. Lagardère https://t.co/ktdX8AWMBo
Regular Fish Intake Supports Cognitive Health in Aging
Fish consumption and cognitive function in aging: a systematic review of observational studies "In conclusion, the evidence suggests that regular fish intake (typically ≥1–2 servings per week) is linked to preserved cognitive performance, although some inconsistent findings require further investigations." https://t.co/1axIS85WGf @GeroScienceAGE
Explore Snap, Crackle, and Pop: Interactive Kinematics Simulator
I have always found it charming that the fourth, fifth and sixth derivatives of position are snap, crackle, and pop. Because I could, I asked Codex to throw together a little simulation so you can play with them (as well...
Science Advances Toward Immortality Through Longevity Hacking
Longevity Hacking: Can We "Cure" Death? "For millennia, humanity has dreamed of immortality, but we are finally living in an era where science is catching up to the dream. "(Sparks) https://t.co/wv28wrTI77 #longevityhackers #longevity #science https://t.co/CTo5hLtD4a
Fine‑tuned DNA Model Achieves Precise Basepair
I spent some time getting the right spacing to accurately model a DNA molecule in basepair length. Almost dialed it in; rotating about its length axis. Will make better :)
Living Robot Oscar Can Self‑heal
Meet Oscar: The Living #Robot That Can Heal Itself by @pascal_bornet #Robotics #AI #Biotech #Innovation #FutureOfTechnology https://t.co/qVQMh6Xztu
South African Virus Matches Argentine Strain, No New Threats
“Genetic sequencing of samples in South Africa suggests that the virus is nearly identical to the version seen in Argentina and has not mutated in ways that would make it a greater threat”-@Tuliodna
Portable Device Detects Real-Time GPS Spoofing On‑the‑Move
Portable detector spots GPS spoofing in real time, even on move by Oak Ridge National Laboratory @TechXplore_com Learn more: https://t.co/JUKIEROcOm #Innovation #Technology #EmergingTech https://t.co/4JevkxiUhG
Continuous Physics Reasoning for Millions of Engineers, Instantly
Most engineers have never had sufficient access to real physics analysis — simulation was too expensive, slow, and specialized. @VinciPhysics vision isn’t just replacing Ansys; it’s bringing continuous physics reasoning to 100x more engineers and 1000x more simulations in a fraction...
Rice Engineers Turn Dead Spiders Into Necrobotic Grippers
Dead Spiders Reanimated as Necrobotic Grippers by Rice University Engineers by @IntEngineering #Innovation #TechForGood #EmergingTech #Technology https://t.co/qlVrochXmQ
AI Unifies Fragmented Spatial Multi‑omics Into Comprehensive Tissue Atlases
A new AI-powered method integrates fragmented spatial multi-omics data, enabling unified tissue atlases and accurate prediction of unmeasured molecular layers across diverse tissues and species. bioinformatics
Finger‑prick Blood Test Accurately Detects Active TB, Predicts Risk
A finger-prick blood test measuring immune response can accurately detect active tuberculosis and moderately predict future disease in household contacts, offering potential for more targeted TB screening and prevention. tuberculosis
Garlic Compound Blocks Mosquito Mating, Offers Green Pest Control
Garlic contains a compound that disrupts mating and egg-laying in mosquitoes and several fly species by activating specific taste receptors, suggesting a potential for eco-friendly pest control solutions. entomology
Starship Test Rescheduled: May 9, 8 Am–8 Pm
🚨New Starship test closure: May 9th, 8 a.m. - 8 p.m. Looks like the WDR has moved a bit. https://t.co/mHpCFWoYEQ https://t.co/lKlErbZJtr
ART Reverses HIV‑Induced Aging, Cutting Years Off Biological Clock
Great news for HIV positive patients. A study presented at ESCMID Global 2026 found that untreated HIV can accelerate biological aging by up to a decade, but antiretroviral therapy can reverse this effect by nearly four years within about 18...
Australia Pioneers Vapor‑grown Lead‑free Perovskite Solar Cells
Australian researchers develop vapour-based manufacturing process for lead-free perovskite solar #energysky -- via pv magazine global: https://t.co/nnRq0u1o8s https://t.co/i7LsyNAx4t
Stop Signals Delay Step Initiation Across Ages
The stop signal stepping task: how action cancellation commands disrupt step initiation in young and healthy older adults https://t.co/bjTuhURJMH https://t.co/9V14LZst7t
AI-Powered Virtual Clinic Transforms Cancer Detection and Care
There is a genuinely a revolution under way in cancer. We're solving it: from early detection (!), trial matching, and ongoing management. @Color is now an @ASCO clinic -- the first virtual-only one -- leading this revolution in screening and...
Andes Hantavirus Shows Airborne Human-to-Human Spread
The detailed investigation of a prior hantavirus human-human transmission event has evidence of airborne transmission of Andes strain: Patient 1 --> Patient 4 "did not have any physical contact and simply said “hello” to each other as they crossed paths" Patient 1 -->...
Psychedelic Figures Don’t Live Longer than Researchers
Psilocybin and human longevity "All groups exceeded population life expectancy, reflecting the effect of socioeconomic advantage on lifespan, but psychedelic personalities did not outlive cancer and aging researchers." 🙂"We examined mortality among prominent psychedelic personalities, researchers, and advocates who claimed psychedelic use...
AI Reads Retina to Diagnose Multiple Metabolic Diseases
In 2014 I predicted we'd diagnose metabolic disease just by looking into your eyes. Nature Medicine just published the proof. Researchers built an AI called Reti-Pioneer. You look into a camera. It scans your retina. No blood draw. No needles. No lab. What it can...
STING Pathway Emerges as New Cancer Immunotherapy Frontier
The number of new potential ways to rev up the immune response to cancer keeps expanding. Today it's STING-ing it. @ScienceMagazine https://t.co/p9g0Mmc8kG https://t.co/LbKfODQkO1
Eta Aquarids Peak Tonight—Watch From Dark Skies After Midnight
Eta Aquarids Meteor Shower peaks tonight. Populated by dust particles left behind by comet Halley. Best viewing will be from a dark location after midnight. Meteors can appear anywhere in the sky but will radiate primarily from the constellation Aquarius
NY Governor Softens Ambitious Climate Law Amid Rising Energy Costs
NY's governor says she's struck a deal to tone down one of the country's most ambitious climate laws amid soaring energy prices https://t.co/yZq3gF9PWQ
International Team Launches Hantavirus Vaccine Development
JUST IN: Scientists from the UK, US, and South Africa formed a team to develop a hantavirus vaccine, per BBC
Light‑powered Micromotors Capture Uranium From Water
Chinese scientists created light-driven micromotors that actively capture uranium from water, offering a new approach to resource extraction challenges. https://t.co/MQB2iNvSXi
Why the Principle of Least Action Dominates All Scales
One question on my mind, is why the principle of least action is so successful and so prevalent at all scales of the universe.
Recent Longevity Pioneer Deaths Urge Faster Breakthroughs
Craig Venter (79), Ham Smith (94) and Clyde Hutchinson (86) died in the span of just 12 months. Time to accelerate, my friends. It would be sad if we land on Mars and don't make a significant breakthrough in longevity......
Aging Boosts Incremental Ideas, Stifles Disruptive Breakthroughs
How is innovation in science impacted by aging researchers? @ScienceMagazine "Aging enhances combinatorial innovation but limits disruptive breakthroughs" @ScienceVisuals Figure showing anchor publication of a scientist typically early in career (top) and declining innovation over length of career (bottom) https://t.co/E2Q6Zzdf4s
GLP Success, Injection Comfort, and Broad Curiosity Fuel Peptide Boom
3 things set the stage for peptides to become a WAY bigger than “supplements”: 1) GLPs (with RCT support) inadvertently made the “peptide” label seem generally approachable 2) GLPs made people less wary of injecting themselves 3) Women & men of many ages...
Moderna CEO Labels Spike Protein “Garbage” In New Vaccine
Whoa. 🫣 This is incredible. Stephen Hoge, president of Moderna, gave an interview on April 17 to the "why should I trust you?" podcast in which he referred to the spike protein — famously in all the Covid vaccines —...
Macrophages Detect Threats Through Cell Volume Shifts
The mechanism by which macrophage cells sense danger to drive an immune response and inflammation has been elusive. A new report highlights change in cell volume as the signal @JCellBiol https://t.co/VQJHtWvczx https://t.co/DQaETZRD0L
China, EU Unite on Carbon Pricing, Challenge Trump
China and the European Union have joined forces in a bid to create a global alliance on carbon pricing, putting them at odds with the Trump administration’s push to invest more in fossil fuels https://t.co/ALnazovHMy
Preprints Safeguard Vaccine Safety Data From FDA Suppression
"The Paper That Didn't Disappear" FDA reportedly held back several vaccine safety papers headed to publication. Fortunately, one was on medRxiv and remains available. Why preprints matter; my latest Substack: https://t.co/YfTbkEPBU4 Also discussed in #healthandveritas podcast. https://t.co/k24zPtoGA2
Modern Physics Has Definitively Discarded the Aether
Why science has abandoned the existence of the aether There are many working in theoretical physics who keep trying to bring back the long-discredited idea of the aether. But physics doesn't need it at all. https://t.co/HpcewdykT0
Evolution Shows GLP‑1s Can’t Substitute Exercise
No pill for exercise: My friend and Harvard colleague, the biological anthropologist Dan Lieberman, invokes evolution to explain why GLP-1s can’t replace physical activity https://t.co/hhN9gCZZmP
AI Poised to Transform Surgery From Planning to Recovery
The impact of AI for surgery (pre-op, intraop, post-op) is going to be extensive A new review https://t.co/04oo4GpQG5 Our previous review @NatureMedicine https://t.co/zDuBUUJUUi https://t.co/V9zDcKQY2K
CRISPR Selectively Eliminates KRAS‑mutant Cancer Cells
The CRISPR Killer as in KRAS mutated cancer cells https://t.co/y1zrmYbIAQ Explainer thread @N8Krah co-author https://t.co/CIweqZMUqY
Hidden Microproteins Reshape Our View of Disease
"The human genome encodes for a new category of molecule" "The ‘dark proteome’ is upending our understanding of human disease" @Nature "Expanding the human proteome with microproteins and peptideins" https://t.co/5ncSKGKHBH https://t.co/2Rx65FJCbG @statnews @MeganMolteni https://t.co/7mATxNQ1EO @TheEconomist
Mild Sleep Loss Alters Blood DNA Methylation Patterns
Prolonged Mild Sleep Restriction Changes Epigenome-Wide DNA Methylation in Peripheral Blood Cells: A Randomized Crossover Trial https://t.co/nb9s0AP9O1
Choosing a Reference Genome Stalls Bioinformatics Before Coding
Bioinformatics is hard before you even write a single line of code. Here's why. 1/ You haven’t started your DNA-seq analysis. You haven’t aligned a read. And yet you’ve already hit a wall. Which human genome to use? https://t.co/nAj5MOqEFm
SGLT2 Inhibitors Cut Cardiovascular Death by 14%
As a medical school professor: when I trained, "diabetes drugs" meant blood-sugar drugs. That ceiling has been broken. Meta-analysis in Am J Med (Jaiswal et al, U Chicago, Mar 26 2026) pooled 18 RCTs, n=95,913 patients with diabetes, heart failure, or...
10‑Marker Bioage Score Outperforms Chronological Age
As a medical school professor: chronological age is a tax bracket. Biological age is the actual bill. Aging Cell paper from MARK-AGE (Moreno-Villanueva, Burkle et al, U Konstanz, 2026) screened 362 biomarkers in ~3,300 adults across 8 European countries, then distilled...
One Year In, Code Works—But Self‑Deception Looms
1/ A year into bioinformatics, your code starts to work. But that’s also when it gets dangerous. Because now you can fool yourself. https://t.co/DM21NQAgjk