
Ok. Here she is in all of her GEO-Interplanetary Class, Spacecraft Carrier, glory. The Blue Ring… https://t.co/5iAPBEBKPG
“And now we have to ask, what is spacetime really? And we know it can’t be as simple as the way we perceive it … I kind of wonder if the next step in really understanding reality is that there’s...

You’ve probably heard that longevity is 20% genetics and 80% lifestyle But that would make it an outlier because almost every other human trait is closer to 50% genetic Dr. Uri Alon is a physicist and systems biologist whose recent research suggests...

In the era of molecular and organ clocks and marked inter- and infra-individual variability of the aging process, we need to move beyond chronological age. "biologic measures predict outcomes more robustly than chronologic age" @NEJM https://t.co/DKmIfdJJUF https://t.co/d5Gc6xGKqn
Blue Ring 1 is coming together nicely and is passing through Safe to Mate testing. Any interest in pictures?

As a medical school professor, I've watched GLP-1 drugs transform diabetes and obesity treatment. Now a Nature Cancer review reveals they may suppress cancer too. GLP-1 drugs reduce insulin resistance, lower inflammation, and cut body weight -- three of the biggest...

TTN shows up as one of the most mutated genes in almost every cancer exome. New bioinformaticians see it and think they found something. They didn't. It's a 364-exon gene encoding the largest human protein. It collects mutations like a lint...
Oral GLP-1 wars, FDA drift, HIV franchise defense, and a few biotech landmines | Ep. 970 https://t.co/sx4kBXzgSL [ 02:30 ] oral GLP-1 battlefield heats up [ 03:08 ] convenience factor drives adoption [ 04:51 ] tolerability issues hit persistence [ 05:45 ] Novo writes $2.1...
"Lactate was at the scene of the crime but was not the criminal. It was actually trying to help" Lactate: The Most Misunderstood Molecule in Biology👇 https://t.co/3skDRDEuqw

Instead of only short bursts of movement, add walks that last 15+ minutes. Among people averaging <8,000 steps/day, those who got most of their daily steps from walks lasting 15+ minutes had the lowest cardiovascular risk and among the lowest mortality...

As a medical school professor, I used to teach that aging is gradual wear and tear. But a Vanderbilt study in Nature Cell Biology reveals something far more disturbing. Your cells are actively dismantling themselves through a process called ER-phagy. Starting early...
A view from Europe on the self-inflicted damage to UK particle, astro and nuclear physics. What a mess this is.
I didn’t expect a piano to make music visible but this does. That caught my attention. Someone spent three years trying to turn sound into something you can see. No AI. No screens. Just experimentation. They tried lasers, smoke, different materials. Nothing worked. Until they found...

Scientists “Bottle the Sun” With Revolutionary Liquid Battery 🔋 ☀️ https://t.co/OwRj1KreUq 💬 Solar energy has one persistent weakness: it disappears at sunset. Finding a reliable way to store that energy for later use remains one of the biggest obstacles to expanding renewable...

β-Hydroxybutyrate, a primary metabolite of ketogenic diets and its dual role in modulating colorectal cancer: from molecular mechanisms to therapeutic insights https://t.co/pPCdm2AcFo https://t.co/mPtz1Xqiep

SIRT6 Regulates Protein Synthesis and Folding Through Nucleolar Remodeling "Our data suggest that SIRT6 deficiency results in proteostasis loss through nucleolar dysfunction." https://t.co/w1SfUiUxg4 https://t.co/5bqVFfS0lg
Latent space data helps us understand the geometry of disease (and health). One simple example is our voice. It can predict future risk for cognitive diseases and other health issues, years and decades before you have clinical presentation.
A new analysis shows that postmenopausal women with higher cardiovascular risk, as measured by the PREVENT score, are significantly more likely to experience major bone fractures, highlighting a close link between heart and bone health. womenshealth

Now THAT is some strong RUBY expression. Filtering transgenic callus a heap of times really pays off. Chasing the red hue without any herbicide or antibiotic pressure. Just hormones to induce callus and careful scalpel work. Some German Chammomile for...
A quasi-liquid layer at the surface of clathrate hydrates accelerates their growth by enhancing CO2 mobility, offering new insights for applications in gas storage, desalination, and carbon containment. materialsengineering
If AI can now solve math, discover physics and chemistry breakthroughs faster than human PhDs, why are we still training humans to be physicists? Serious question. Should education shift from 'learn to do X' to 'learn to direct AI doing...
Latent Space as a Physiological Map: All our medical data, genomes, scans, notes are just different shadows of one underlying physiological state. Health = a point in high-dimensional space. Disease = a drifting trajectory Treatment = a vector,...
NASA released details of the ISS medical evacuation of astronaut Mike Fincke in January 2026 #space #astronomy #science https://t.co/Juis0InB8P
“Huntington’s Disease and The Triad of Therapeutic Conviction”. Debut blog from Eric Green, CEO of Trace Neuro, explaining why and how advances are happening in HD. Genetics, cellular understanding, and enabling modalities. https://t.co/pAr9EQs5gJ
This is so awesome. @JohnSchloendorn and Alice Gilman at R3 Bio talk through what they’re doing at R3 Bio: building something that's never existed before. They're designing genetically engineered whole organ systems. See them featured in WIRED. @WIRED full story here: https://t.co/8z5iGXR0uK
The Trump administration is talking with some offshore wind developers about buying back the leases they purchased from the federal government years ago to develop energy projects along the US coast https://t.co/w6VR2H3AC3
Brown fat loses its heat-producing function with age due to epigenetic changes that reduce activity of key genes like PGC1A, with specific enhancers playing a critical role in maintaining this function. https://t.co/Dnnawd5r41
Solar and wind are making remarkable progress. The day/night cycle will be solved by current economic battery trends. The real long term challenge has always been winter: Those dark winter days or weeks when the wind also fails. For that...
French energy giant TotalEnergies says it will no longer aim to reach net zero emission targets by 2050 https://t.co/oJaqzNTGaQ
Researchers found that the cholesterol-related protein SREBP-2 can trigger apoptosis under stress by interacting with IRAK1, revealing a new mechanism for how cells self-destruct. This suggests that beyond telomeres, which signal aging through gradual shortening, cells can also initiate death...
The Bitter lesson from AI applied to today's Bio AI models tells us most will be washed away with raw compute and data. Today's Startups and Academics will (mostly) fight it but that too will fall. Raw compute and data is what...
Aging may or may not be classified as a disease, but that’s largely semantics. What matters is that aging is a malleable, targetable biological process, and slowing human aging would result in massive health benefits.
JPMorgan’s institutional clients have started paying more attention to so-called tipping points in climate https://t.co/MkV9vxVmwj

Local warnings and at least one NOTAM indicate an upcoming launch from Plesetsk between April 1 and 15 to an orbit with an inclination 63 degrees toward the Equator: https://t.co/EhSC0xsQVM https://t.co/E7nBV3xpBV
Ask Ethan: Does dark energy curve the Universe over time? Our Universe was once ruled by radiation and matter, but those densities eventually dilute. Would spatial curvature appear? Even if it did, dark energy now flattens the Universe once again. https://t.co/zF67EySaRB
In 1992, scientists discovered a chemical in Gila monster venom that mimicked GLP-1, the hormone your gut releases to signal fullness. By tinkering with its structure, pharma companies extended its duration from two hours (the Gila monster version) to one...
Artemis II crew is enroute to KSC. Expected to land abt 2:30 pm ET. NASA's Jared Isaacman and CSA's Lisa Campbell will be there to greet them. Crew then will answer questions from the media. Full list of public...
Today on Volts: at this point, it is all but inevitable that global temperatures will exceed the 2° threshold & continue rising. Should we shoot sulfur particles into the stratosphere to block some of that heat? I talk with the...

Is NAD+ a key factor in ovarian aging and dysfunction? Insights and uncertainties from current research https://t.co/OWU1Hhcreu https://t.co/IH7uKdRsa9

When you put your finger in a newborn's palm, they grip it so hard it is almost shocking. It is called the palmar grasp reflex. It is strong enough that some newborns can briefly support their own body weight hanging...
Out at sea, a Canadian whale scientist witnessed something close to a miracle /via @globeandmail https://t.co/nykQ2LNHh4
AstraZeneca lung drug gets ‘surprise’ win in COPD trials https://t.co/QuRlOQtzdT @ByJonGardner $AZN $RGN $SNY $RHHBY
Cryonic preservation is pricey and might never work. Some people think it’s worth it anyway.
No one, it seems, is happy with NASA's new idea for commercial space stations. https://t.co/SVhXpYQAnK

Is sun avoidance a risk factor for mortality?☀️ In this 2014 study from Sweden, sun avoidance was associated with nearly a 2x higher rate of all-cause mortality compared to the most active sun exposure habits. They did find increased risk of malignant...

Kudos to @UCLAHealth for assessing genomics of their patient population, published @CellCellPress today. But why weren't the results of increased polygenic risk scores (PGS) provided to the patient participants? https://t.co/F15isJfDQy https://t.co/3AW7peHa1C
The Shocking Speed of China’s Scientific Rise When will Chinese research pull ahead of the U.S.’s? https://t.co/BBemz3lomx
This adds to the building story for ergothioneine, which we covered in a deep dive (2h): https://t.co/VvaoPbC3eB
Now at 1M+ views. What struck me most here wasn’t the views. It was the engagement. People are ready to engage seriously with aging biology. Now the opportunity is to turn that energy into stronger collaboration, better translational science, and...
LENG8 has been identified as a key protein that monitors and controls RNA quality in cells, ensuring only properly processed RNA is exported from the nucleus while defective RNA is retained and degraded. molecularbiology