Owls See with Sound: Strange, Wondrous Science
What it's like to be an owl – the strange and wondrous science of seeing with sound https://t.co/72zn2DgTE4
Digital Aging Twin Links Liver Coagulation to Systemic Aging
A new computational framework, the Digital Aging Twin, quantifies how different organs age at varying rates and identifies liver-derived coagulation factors as direct drivers of systemic aging, offering a precise tool for personalized aging assessment. agingbiology
Organ Age Asynchrony Predicts Mortality Risk
From ageing clocks to organ networks: Biological age-driven organ asynchrony and inter-organ interactions shaping mortality risk https://t.co/y02SJj7q2q https://t.co/ObuzzNQczW
Digital Twins of Human Lungs Personalize Therapy Assessment
Digital twins of ex vivo human lungs enable accurate and personalized evaluation of therapeutic efficacy https://t.co/0FMBqmiMyM https://t.co/3MrdTqK82w
Merging AI Pattern Recognition with Mechanistic Models Enables Virtual Cells
Minimal life by computer 👉 Progress toward a true virtual cell will depend on uniting AI’s pattern-finding power with the causal rigor of mechanistic models. https://t.co/2VYeaYCEUj @NatureNano https://t.co/nQGCjX7cna
Hantavirus Outbreak Signals Emerging Long‑term Health Trends
1/n: I could be wrong, of course, but my take about this hantavirus outbreak is less about the actual outbreak and more about what it means in the context of the last two decades and moving forward. Let me...
DOSE Trial Reveals Best Heart Failure Infusion Strategy
Bolus or drip? What the DOSE trial actually showed about heart failure [PODCAST] http://dlvr.it/TSV5l4 Podcast #Cardiology
COVID Spread Can Occur without Close, Prolonged Contact
Really good from @PaulSaxMD “In this outbreak in particular, we are still learning about how transmission occurred. Some infected individuals reportedly did not have prolonged close contact, suggesting that simple assumptions about risk may not fully explain what happened aboard...
Outbreaks Prove Strain Doesn't Need Close Contact
Why is everyone ignoring evidence from outbreaks of this specific strain that are *very* clear that it doesn’t require prolonged close contact?
NZ Moves to Block Private Climate Lawsuits, Citing Investment Concerns
New Zealand’s government plans a law change to prevent private legal action against greenhouse gas emitters, arguing cases have created business uncertainty and deterred investment https://t.co/Bhd92C3bJ5
Measure Biology, Not Trends, to Extend Longevity
Most people are trying to optimize their health without ever measuring what actually matters. The reality is: aging is a biological process you can track (and in many cases, influence) when you know what to look for. Longevity isn’t built on trends....
Proteins Can Directly Template Sequence‑Specific DNA Synthesis
For 50+ years, molecular biology followed one golden rule: DNA ➜ RNA ➜ Protein 🧬 This new Science paper just added a shocking new twist: 🧪 Proteins can DIRECT sequence-specific DNA synthesis — without a nucleic acid template. 🤯⚡ Yes, you read that right. A...
One‑point Mediterranean Diet Boost Cuts Mortality by 4%
Adherence to the Mediterranean diet and all-cause mortality: A systematic review and meta-analysis within the Italian National Guidelines “La Dieta Mediterranea” "Each 1-point MD score increase reduced mortality risk by about 4%." https://t.co/l1VEnyEb29 https://t.co/RU5hAnNG1n
Observed Warming Aligns with Climate Model Expectations
"Heating Up to Expectations" | Press release on our new @PNASNews article (via #MichaelMannBlog): https://t.co/ZCGzybvPYs
2024 Temperature Record Validates Climate Model Forecasts
"2024 global temperature record is consistent with model-predicted warming" | Our new article in @PNASNews (open access): https://t.co/wozp1qu3xa
AI's Cure‑finding Will Be Slow without Real‑world Data
1. Sounds like an urban legend. 2. I hope so, because AI progress in curing diseases is going to be a slow process, slowed by layers of experimentation and trials; and bottlenecked by real world data. We just don't have...
Two Decades, Twenty Papers: ETH Quantum Device Lab Milestone
20 Papers from 20 Years of the Quantum Device Lab (@qudev ) at @ETH_en #Zurich. https://t.co/HbtxwXWtcF
Questioning CDC's Current Primer Design Standards and Tools
Jokes aside, what's the current CDC protocol for primer design? Are they using Primer3? Are they using a modern thermodynamic model? Still with that GC clamp juju? I keep hearing primer issues being brought up but thats practically solved...
Moscow Startup Plans First Distributed Solar Observatory Using Cubesats
Moscow-based small satellite developer proposes the "world's first distributed solar observatory" comprised of cubesats spread from Earth's orbit to Lagrange points. https://t.co/oSSdHr16A1
Low‑dose Cialis May Protect Brain Vascular Health, Curb Dementia
ED drugs like Cialis & Viagra, when taken as a low dose daily, can help maintain vascular function in brain and muscle, and are a promising, though still debated, approach for preventing & treating dementias. The human data for Cialis...
Oxygenated Water Boosts Cycling Performance, Study Shows
Can oxygenated water improve athletic performance? In this blog, Dr. Nick Tiller and I discuss findings from a study showing oxygenated water improves cycling performance... Read here: https://t.co/QPFqrbCatN https://t.co/XJ79CryBeH
NASA Pushes Starliner-1 Cargo Demo to 2027
In news that should shock no one, NASA has moved the "Starliner-1" mission from June 2026 on its internal calendar to "under review." This is an uncrewed cargo demonstration flight. Since we've heard very little about this, a slip into...
Self‑aware Robots Share Skills Across Joint Constraints
A Science #Robotics study classifies robots according to their joint constraints and endows them with this self-awareness, enabling diverse robots to learn the same skill safely and without retraining. https://t.co/fAPjb5AcEl https://t.co/ttO8voua0w
Andes Hantavirus Low Transmissibility, Unlikely Pandemic Risk
So Andes hantavirus is infectious, but not very infectious. PCR positive a few days before symptoms. This does not have the makings of a widespread pandemic.
From Millions to 30 Billion Light‑Years: Expanding Cosmic Horizons
A brief history of the cosmic distance record The cosmic distance record has grown, in just a few hundred years, from millions of light-years to over 30 billion light-years. Here's a look back at our history of ever-receding horizons. https://t.co/ahMqrg2lL8
GLP‑1 Drugs Boost Survival, Cut Recurrence in Obese Breast Cancer Patients
In women with breast cancer and obesity or T2 diabetes, a large propensity matching retrospective analysis reports association of GLP-1 drug therapy with improved survival and reduced risk of recurrence https://t.co/GjimCr97S0
Three Patients Sparked Four Airborne Transmission Waves
That prior on-land outbreak? --> 3 patients were main drivers of the outbreak --> 33 secondary cases --> *** 4 waves *** of transmission How did it spread? --> "the route of infection in secondary cases was possibly through inhalation of droplets or aerosolized virions" This...
GNPS2 Enables Comprehensive Drug Metabolism Toolkit
Nature Protocols: A versatile toolkit for drug metabolism studies with GNPS2: from drug development to clinical monitoring https://t.co/lEejrO6gXT https://t.co/qlybcRgD9V
Fractyl Secures Dutch CTA for First GLP‑1 Gene Therapy Trial
Fractyl Health today announced that it has received Clinical Trial Application (CTA) authorization in the Netherlands to initiate the Phase 1/2 first-in-human study of RJVA-001 - $GUTS first clinical candidate from its Rejuva 🧵👇 GLP-1 Gene Therapy platform and the...
Rare Disease Community Gains New Treatment Hope After Five Years
Five years after disaster, a rare disease community gets new chance at treatment Yet another heart-rending story from @Jasonmmast. https://t.co/9vgOKpInL3
Epic 175‑Tweet Deep Dive Into Embryonic Stem Cell History
This lab is drum rolling an upcoming epic tweet storm of 175 tweets on the history of stem cells (embryonic). Can we get a postscript chapter on synthetic embryos/embryoids?
Exercise‑induced Exosomes Deliver NAMPT, Boost NAD, Protect Liver
Interesting new paper: In old mice, exercise releases bubble-like blood vesicles called "exosomes" carrying NAMPT, the enzyme that makes NMN Evidence indicates NAMPT's ability to raise NAD and activate liver SIRT1 may be why exercise counteracts fatty liver and fibrosis 🏃♀️🏃♂️...
Vascular Dysfunction May Drive Cognitive Decline and Dementia
Emerging research links vascular dysfunction to cognitive decline in aging & dementia. Reduced blood flow and blood-brain barrier breakdown may play a key role—and could even be causally connected. Understanding this opens the door to new, much-needed therapies. #Neuroscience #Aging...
Moonfall Mission Deploys Four Ingenuity‑Based Drones to Lunar South Pole
Got out on a new mission and just have to share how cool of a name it is: Moonfall Not only does it sound like a movie (I think it actually was), but the mission will send 4 drones to explore...
Swallowable Soft Robot Measures Stomach Acidity Without Endoscopy
A swallowable, electronics-free soft robot enables real-time stomach acidity measurement and fluid sampling, offering a less invasive alternative to endoscopy by gliding through the stomach and transmitting data via ultrasound. medicalinnovation
Hantavirus Detected on Ship: Risk Remains Unclear
Why the "mildly" is irrelevant here: -we were simply watching for if any other passengers tested positive; not the viral load -the important part of the result is that *the test showed another passenger has hantavirus*. That means people still getting sick...
POD24 Signals Urgent Need for Wise Management
POD24 in follicular lymphoma: time to be “wise” [Mar 17, 2022] @JohnPLeonardMD @BloodJournal https://t.co/jLMd14D4Ur #lymsm https://t.co/991dNQe3JH
First‑line Lymphoma Therapies Linked to Higher Osteoporosis Risk
Increased risk of osteoporosis following commonly used first-line treatments for lymphoma: a Danish Nationwide Cohort Study [Feb 11, 2020] Baech et al. Leukemia & Lymphoma https://t.co/oapmDJlQV7 #lymsm #BoneHealth #SuppOnc #geriheme
PET‑CT Can Opportunistically Assess Bone Density in Hodgkin Lymphoma
Opportunistic Evaluation of Bone Mineral Density by PET-CT in Hodgkin Lymphoma Patients [Jun 6, 2019] Cohen et al. Endocr Pract https://t.co/jdxVy80vMB #lymsm #supponc #oncorad #BoneHealth
Prefrontal Cortex Guides Hippocampal Memory Encoding, Explaining Disorders
New findings show that the prefrontal cortex directs which hippocampal neurons encode new experiences, shaping how memories are linked or kept separate—a mechanism that may clarify memory disruptions in schizophrenia and cognitive decline. neuroscience
Zoledronic Acid Prevents Bone Loss in Lymphoma Therapy
Zoledronic Acid for Prevention of Bone Loss in Patients Receiving Primary Therapy for Lymphomas: A Prospective, Randomized Controlled Phase III Trial [Dec 29, 2012] @Lymphoma_Doc @mtmdphd et al. CLML https://t.co/iPOYSXEA1M #lymsm #SuppOnc #BoneHealth #NCT00352846 https://t.co/UlaqHyy65d
Mild Animal Skin Disease Detected in MSM, No Livestock Contact
Doctors in several European cities are seeing cases of an animal skin disease in men who have sex with men who haven't had contact with the livestock that normally contract this disease. The good news is, it's mild & treatable....
Many Common Surgeries Fail to Outperform Placebos
Imagine a pill that works no better than a sugar pill BUT still gets prescribed thousands of times a year. That's the state of these surgeries: Vertebroplasty- no better than sham (NEJM, 2009) Knee arthroscopy for OA- no better than sham (NEJM, 2002) Meniscectomy-...
Resistant Starch Cuts Visceral Fat, Yet Responses Vary
Resistant starch has been shown in multiple randomized controlled human trials to reduce visceral fat. Today’s video (link below) dives into the data, and why individual variability in response matters.
Super‑heating Event Threatens Climate Risk Pricing for Insurers
The possibility of a super planet-heating event, which would make extreme weather impacts more likely, is challenging underwriters pricing climate risks. https://t.co/Ypdjlpl1jf
EU Updates Carbon Market Benchmarks to Boost Competitiveness
The European Commission proposed updated benchmarks for its flagship carbon market to address concerns over the region’s declining competitiveness https://t.co/Rc7zvWTj8g
Brain Blood Flow Peaks Differ by Region Daily
Blood flow to various parts of the brain follows a daily rhythm 🧠 Regions like limbic & sensorimotor areas peak around midday, while the hippocampus has more blood flow at midnight—and shows the strongest connectivity with the brain’s master clock...
Evolutionary Psychiatry Reframes Disorders by Function, Not Symptoms
Evolutionary psychiatry: Illuminating disorders by the ultimate functions of emotion and thought patterns, not an inventory of symptoms. Overview essay by one of its pioneers, Randolph Nesse - 2023 - World Psychiatry - Wiley Online Library https://t.co/x7TOk0V0u2
Decoding Epigenetic Clocks: Pathways Behind Accelerated Aging
How epigenetic clocks tick: Unpacking the black box by deciphering biological pathways and transcriptomic signatures of accelerated aging https://t.co/MU3R25TEu3
GrimAge Predicts Mortality in Centenarians Beyond Immune Aging
Advances in precision geriatrics. GrimAge methylation clock works in centenarians. Striking new preprint from the Henne Holstege lab (Yaran Zhang et al., 100-plus Study) in n=247 cognitively healthy Dutch centenarians: GrimAge predicts mortality at extreme old age (HR ≈ 1.6...