AstraZeneca lung drug gets ‘surprise’ win in COPD trials https://t.co/QuRlOQtzdT @ByJonGardner $AZN $RGN $SNY $RHHBY
Cryonic preservation is pricey and might never work. Some people think it’s worth it anyway.
No one, it seems, is happy with NASA's new idea for commercial space stations. https://t.co/SVhXpYQAnK

Is sun avoidance a risk factor for mortality?☀️ In this 2014 study from Sweden, sun avoidance was associated with nearly a 2x higher rate of all-cause mortality compared to the most active sun exposure habits. They did find increased risk of malignant...

Kudos to @UCLAHealth for assessing genomics of their patient population, published @CellCellPress today. But why weren't the results of increased polygenic risk scores (PGS) provided to the patient participants? https://t.co/F15isJfDQy https://t.co/3AW7peHa1C
The Shocking Speed of China’s Scientific Rise When will Chinese research pull ahead of the U.S.’s? https://t.co/BBemz3lomx
This adds to the building story for ergothioneine, which we covered in a deep dive (2h): https://t.co/VvaoPbC3eB
Now at 1M+ views. What struck me most here wasn’t the views. It was the engagement. People are ready to engage seriously with aging biology. Now the opportunity is to turn that energy into stronger collaboration, better translational science, and...
LENG8 has been identified as a key protein that monitors and controls RNA quality in cells, ensuring only properly processed RNA is exported from the nucleus while defective RNA is retained and degraded. molecularbiology
Brain benefits of intense exercise, including impulse control @foundmyfitness on the Huberman Lab podcast out now. https://t.co/ikb1qKevnc
Outstanding piece here from @leilei_wuu on AstraZeneca's in vivo CAR-T for multiple myeloma. There's data on 5 patients, which is pretty lean, but 4 come out MRD negative in two months, which is extraordinary. We're going to see a lot...
ReCoSplat: Reconstructing 3D Worlds From Sparse Visual Data In this episode of Artificial Intelligence: Papers and Concepts, we explore ReCoSplat, a novel approach to 3D scene reconstruction that leverages sparse visual inputs to generate detailed spatial representations. Instead of requiring dense...
As someone who has covered cancer drug development for 25 years, one of the few things I am sure of is that the odds of technology folks thinking they understand biology are much higher than the odds they actually do.

Shared and specific blood biomarkers for multimorbidity "Metabolic disturbances emerged as a key driver of multimorbidity. If confirmed, these processes could represent targets for interventions to mitigate disease accumulation." https://t.co/3nuctP2eAC https://t.co/yxk5CZHiHV

As a medical school professor, I teach my students to prescribe drugs. But a landmark review in Cell Metabolism argues we should prescribe exercise first. Febbraio and Pedersen -- the scientists who coined "exercise as medicine" -- reviewed 233 studies on...

As a medical school professor, I was trained to focus on WHAT patients eat. But this massive meta-analysis says WHEN may be just as important. 41 randomized controlled trials. 2,287 participants. Published in BMJ Medicine. The finding: time-restricted eating improved nearly every...
When we seeded Denali the idea was to break the curse of the blood/brain barrier. It took a decade and tons of faith and money. Biotech is hard. Curing diseases is hard. This is a good summary. ...

It was a pleasure to participate in the Investment and Innovation Pathways to a Healthy Asia session at the Global Investors’ Symposium in Hong Kong. A timely discussion on where durable value is being created in healthcare across Asia, from prevention...
The life of a chemist is about to change dramatically as we move away from tedious trial-and-error and deeper into the comfort of the prompt window. We don't need fewer medicinal chemists; we need more high-novelty drugs on the market...

Efficacy of Alpha-Lipoic Acid in Patients With Ischemic Heart Failure: A Double-Blind, Randomized, Placebo-Controlled Study | @JACCJournals https://t.co/nW9SbwEDfy https://t.co/qsemjmMb9k

Measurement-induced non-commutativity in adaptive fermionic linear optics We show that mid-circuit measurements of fermions with internal degrees of freedom can induce the equivalent of "magic" to free fermionic circuits and render them classically hard to sample. https://t.co/r7rZBcyLHL Fermionic linear optics (FLO) with Gaussian...
The coolest meeting I had this week with was Paul, who used ChatGPT and other LLMs to create an mRNA vaccine protocol to save his dog Rosie. It is amazing story. "The chat bots empowered me as an individual to act...

GLP-1 and the cardiovascular system "This Review summarizes the effects of GLP-1 and GLP-1RAs in the CV system..." https://t.co/Sy7Jjb96WD https://t.co/v3T01fIcOs

Scientists demonstrate quantum battery prototype with rapid charging #energysky -- via pv magazine global: https://t.co/AxphAp5wAP https://t.co/HjngLBmLdA

Billionaire-backed scientists aim to grow 'headless humans' to farm their organs... and help biohackers live for longer https://t.co/uQOzEtBapf https://t.co/HYZCMCOPy3
Serum uric acid levels and longitudinal change in cognitive function in older adults: a sex-stratified population-based study https://t.co/vl5LLY6mBc
Great to see a new work showing that C1ORF112 is upregulated in tumor tissues and that it promotes breast cancer proliferation. We computationally predicted C1ORF112 to be related to cancer back in 2012, and we were the first to study and...
Nicotine e-cigarettes are linked to quit rates 20% to 40% higher than traditional nicotine replacement therapies, with consistent evidence showing greater effectiveness for smoking cessation over at least six months. smokingcessation
Genetic analysis has confirmed the Galapagos lava heron as a distinct species, overturning decades of classification and highlighting the ongoing evolutionary mysteries of the islands. ornithology
Discontinuation of maintenance therapy in multiple myeloma guided by multimodal measurable residual disease negativity (MRD2STOP) - @bdermanmd et al. @ajjakubowiak #ASCO24 Abstract 106 https://t.co/FBTY7SnCxK #NCT04108624 #mmsm #mmMRD

Clinician attitudes and practices toward measurable residual disease in multiple myeloma [Jun 7, 2020] @bdermanmd @jagoda_jasielec @ajjakubowiak Brit J Haematol https://t.co/8zhxYfYwZQ #mmsm #mmMRD https://t.co/lbZ4AFZ1YM
NASA will unveil the Nancy Grace Roman Space Telescope -- which Nicky Fox cheers as under budget and ahead of schedule -- at Goddard Space Flight Center on April 21. Press bfg at 4:00 pm ET will be on YouTube....

A ~20% reduction in New Glenn capacity compared to the originally expected 61 satellites... https://t.co/H4l2vyx0DP

Scientists have developed soft artificial electrofluidic fiber muscles that can be bundled together like skeletal muscles to lift heavy weights or launch objects in the blink of an eye. Learn more in Science #Robotics: https://t.co/QigPsEJDBc https://t.co/46eSTl1Y53
New Paper - Evidence suggests regeneration may be a natural and achievable biological process worth prioritizing over merely slowing aging—ideally beginning in midlife (around 40–60) to postpone decline, with the potential to reverse aging later in older individuals. Insights from...
MARVEL: The Portable Microreactor Powering Electricity, Heat, and Clean Water by @tweetciiiim #Innovation #EmergingTech #TechForGood #Technology https://t.co/gcf8YkLij0

Engineers developed a tiny 20-milligram tag to track wasp movements. To meet weight constraints, they couldn’t afford to put a battery on the tag and had to resort to a capacitor to send a radio pulse. https://spectrum.ieee.org/rf-tags

Most cancer drugs go after the same targets: EGFR. PD-L1. HER2. Not because they’re the best targets. Because they’re the only ones we’ve been able to see. RyboDyn Inc. is going after what’s been invisible. The San Diego team, led by Imad Ajjawi, PhD,...

NAD⁺ supplementation for anti-aging and wellness: a PRISMA-guided systematic review of preclinical and clinical evidence https://t.co/au5YIC11Hw https://t.co/fMsAOSQF6f
Really excited to share new VR research for IBS symptom support. Our NIH-funded randomized trial is showing notable benefits, and we’re presenting it today at #vMed26.

🆕 @ScienceMagazine How do our cells have long term memory of inflammation that can later lead to persistent, chronic inflammation and disease? Through specific epigenetic chromatin changes, aka "memory domains" @ScienceVisuals https://t.co/mt70OwH144 https://t.co/DMk7SaIuBc https://t.co/FaPpN0331q

Optimal randomized measurements for a family of nonlinear quantum properties: We answer how non-linear quantities can be estimated with the same standards as expectation values in classical shadows. https://t.co/6e3fWUyL0p Quantum learning encounters fundamental challenges when estimating nonlinear properties, owing to the inherent linearity...

At #vMed26 we’re not just seeing the future of medicine, we’re tasting it 🍫😄 This poster shows how aligning sight, touch, and taste can make a virtual chocolate bar feel real. It’s one of 40 highly creative projects in this year’s...

The problem of AI sycophancy addressed in the new issue: @ScienceMagazine cover and original research by @chengmyra1 and colleagues https://t.co/P8112DRIIH https://t.co/7natpzaVpG

Pleased to join the Scientific Advisory Board at @LifespanRI, an organization dedicated to accelerating research on age-related disease and extending healthy human lifespan. Looking forward to contributing to this important work. 🚀 https://t.co/HSdyrtABCK https://t.co/754TAi6znw
The Arctic's winter sea ice shrank to a record-low level for the second year running, a sign of how climate change is reshaping the region https://t.co/VZQkqvH89X
The widely reported “hole in the Universe” is a lie It's 2026. There still isn't a hole in the Universe, and the famous nebula they always show when describing it doesn't have anything to do with the Universe at all. https://t.co/91kWOrNZTD

Fusion power plant possible by 2045 with massive effort, says science academy #energysky -- via Renew Economy: https://t.co/wmE6rq570P https://t.co/FjHhMUqKyq

Writing a talk that includes this gem from Apollo 12 so thought I’d share it! Also if you know where those TV transmissions might live let me know, Google has truly become crap as a search engine. #author #history #space...

"A much stronger cancer-preventive potential of obesity prevention and control than previously established" https://t.co/QatHKVMbfz @JAMAOnc https://t.co/OQ62MunGTu