High Hs‑CRP, Not LDL, Drives Statin Benefit
"But my cholesterol is normal." JUPITER trial (NEJM): 18,000 people, normal LDL, high hs-CRP. Statin → cardiac events ↓44%, heart attacks ↓54%, strokes ↓48%. 322,000-person UK Biobank: hs-CRP outranked LDL. Full episode 🎙 https://youtu.be/FBLB1CQGBPM
Climate Change Fuels Emerging Infections; Defunding WHO Is Reckless
No I don’t think so, usually hantaviruses are not as transmissible person-to-person as coronaviruses, but it’s another reminder of the risk of global infections emerging due to climate change, globalization, and why it’s reckless to defund @WHO @CDCgov
Longevity Genes Can Switch From Benefit to Harm
As a medical school professor, I tell students: be careful with "longevity gene." Prof. Nikolai Slavov (Northeastern) just argued that single "longevity genes" are oversimplified. The same gene's effect on lifespan can flip sign with age -- helpful early, harmful later....
Invasive Nanowire BCIs Needed, Non‑Invasive for Biomarkers
I love brain-to-computer interfaces and one of my first papers and granted patents was in AI/ML for BCI. And I was very much impressed with BrainCo's non-invasive BCIs and artificial limbs and sensing fingers (that they sell to Tesla btw)....
Photonic‑Crystal Laser Beams Data Across River in First Demo
The laser inside your 4K Blu-Ray player is dim and unfocused. A newer kind, built from photonic crystals, is so bright and directional it can beam data across a river with minimal hardware. A Glasgow company just showed it working...
Quiet Hurricane Season Still Threatens US Power Grid
This Atlantic hurricane season could be on the quiet side. But seasons with a lower number of storms can still do major damage to the US power grid https://t.co/YNJRTdjMyz
Extracellular Vesicles Deliver SASP, Fuel Aging, Offer Therapies
Extracellular Vesicles as Key SASP Carriers Driving Cellular Senescence, Inflammaging, and Therapeutic Opportunities in Aging and Age-Related Diseases https://t.co/SURS5ZbTD9 https://t.co/IXM2BkdurZ
Targeted Therapies Resurge; some Phase 3 Trials Risk Obsolescence
With a rapid fire raft of trial updates coming out of #esmobreast26, one thing stood out... targeted molecules are back in fashion and a few companies might be left holding the baby if their phase 3 trials have already started: https://t.co/jlKDLsecVZ...
LabClaw Goes Autonomous in LifeStar 2.0 Lab
Cool news - we launched LabClaw in our LifeStar 2.0 lab. It can now run multiple projects autonomously, learn new skills and evolve. https://t.co/ukRqpgiVXP
Energy Transition's Financial and Political Hurdles Explored
Professor Emily Grubert joins the Zero podcast to discuss the difficulty of managing the financial and political costs of the energy transition https://t.co/lmaFu7dp1J
Record‑breaking El Niño Offers Early Glimpse of 2035 Climate
"A climate monster is growing in the Pacific Ocean, perhaps the most fearsome El Niño since before scientists even began modeling them. It will give us at least a brief preview of a hotter and more chaotic world — a...
Andes Hantavirus Sparks Complex Public‑Health Challenge
Hantavirus outbreaks rarely happen. This Andes strain is ‘a complicated public-health situation.’ @jaimy_lee reports https://t.co/Tqqt7pODWB via @MarketWatch
Tiny BCI Chip Delivers High‑Bandwidth Wireless Neural Links
Ultra-Compact Brain–Computer Interface Chip Enables High-Bandwidth Wireless Neural Communication by @CUSEAS #MedTech #Healthcare #HealthTech #Tech #Technology https://t.co/nWSUX4xCRz
Global Temperatures Set to Break Records Next Week
The next week is looking like it might be toasty for global temperatures in the latest model runs. If this holds it would put us well into record territory for this time of year: https://t.co/FdGqR3FlU3 https://t.co/doCUvDKqKU
Oncology Care Ignores Patient Survival vs QoL Preferences
"Patient preference for extending survival or maintaining QoL was not associated with up-front treatment modifications or downstream outcomes, suggesting a possible lack of responsiveness of the current oncology care delivery system to patient preference." https://t.co/0RXf4h2dr3 In: Outcomes of Older Adults With Advanced...
Early Adversity Predicts Later Functional Decline and Multimorbidity
Adverse childhood and adult experiences, intrinsic capacity decline, and subsequent physical-psychological-cognitive multimorbidity: a prospective cohort study from China "Childhood adversity is associated with reduced intrinsic capacity in later life, reflecting early functional vulnerability, while both childhood and adulthood adversities contribute to...
Cruise Ships Amplify COVID: R0 Jumped to 14.8
Don’t forget, on the Diamond Princess Cruise early in the COVID pandemic the Ro reproductive number for the original lineage went from around 2 to 14.8, cruise ships can be a crucible for respiratory viruses https://t.co/uTxKalftA7
Obesity Requires More Than Lifestyle Changes, Biology Matters
Why Lifestyle Alone Is Insufficient in Obesity: Biological Evidence, Conceptual Analogies and a Legacy of Missed Opportunities in Patient Care https://t.co/MOXZrDVWZD
Unfunded $24B Could Have Delivered 100‑Day Prototype Vaccines
Every so often I think about how, in 2022, for $24B we could had "prototype vaccines ready for each of the 26 known viral families that cause human disease" so they can be deployed in 100 days if there was...
Disorder Enables High Efficiency in Lead‑Halide Perovskites
Scientists discover why lead-halide solar perovskites work efficiently despite being structurally ‘messy’ #energysky -- via pv magazine global: https://t.co/NTeLaiE7Uw
Hummingbirds Defy Physics: The Science Behind Their Hover
Between science and magic – how hummingbirds hover at the edge of the possible https://t.co/8YHI3TgsBb
Dr. Katharine Wilkinson Guides Our Climate Crisis Navigation
This week's edition of Talking Climate features guest editor and fellow climate Katharine, Dr. Katharine Wilkinson, as she helps us navigate our way through the climate crisis.
Cut Ultraprocessed Foods to Lower Heart Disease Risk
A consensus statement from @escardio today to limit intake of ultraprocessed foods for reduced risk of heart disease https://t.co/5spHDVmkb3 https://t.co/GvTvcVzzjD
SIRT6 Shields Aorta by Cutting Inflammation and Aging
SIRT6 appears protective in aortic disease, as higher levels reduce vascular inflammation and smooth muscle cell aging, thereby helping prevent both aortic aneurysm and dissection progression. https://t.co/eXuKrR7oNF
AI Speeds Dangerous Bio Design; Economics Drive Safety Race‑to‑bottom
"What keeps me up at night is the fast pace of acceleration of open weight models in the ecosystem. They do not prioritize the same type of safety refusals." - Yunyun Wang, @OpenAI We just ran a biosecurity panel at...
Even a Dog Loves Scaling Virtual Biology Panel
Not all our #SynBioBeta2026 attendees walk on 2 legs 🐶 Taco here found the "From Cells to Patients: Solving the Scale Mismatch in Virtual Biology" Main Stage Panel particularly interesting. https://t.co/6xMHnozSqd
Socioeconomic, Lifestyle, and Genetic Factors Jointly Shape Intrinsic Capacity
Associations and interaction effects of socioeconomic, lifestyle, and genetic factors on intrinsic capacity https://t.co/crOBp21bRN https://t.co/LgbFdA0GEe
Bed Rest Lowers Cholesterol, Raises Insulin Resistance and Inflammation
The effects of bed rest on cardiometabolic health: A systematic review and meta-analysis "HDT lowered total cholesterol but increased insulin and homeostatic model assessment for insulin resistance, and both reduced high-density lipoprotein cholesterol. C-Reactive protein increased with HBR, and tumour necrosis...
Supercomputers Reveal Tectonics Direct Yellowstone’s Magma Paths
Chinese researchers used supercomputers to model Yellowstone, revealing that tectonic forces shaped magma pathways and sparking ambitions for full planetary simulation systems. https://t.co/K2BkE8z7JY
First‑in‑class Molecular Glue Shows Breakthrough Pancreatic Cancer Results
We're seeing major advances vs pancreatic cancer. Today @NEJM data for daraxonrasib @RevMedicines https://t.co/IinceclK6w Context for this first-in-class molecular glue https://t.co/IinceclK6w https://t.co/odhmXQqzMF
Quick Turnaround: Good Longevity Trial News Arrives
I post about working around longevity clinical trials and an hour later @j_n_justice tells me good news about longevity clinical trials... 😍
Hant
I'm not in full-blown panic mode about the hantavirus outbreak - the most plausible situation is that it's not that transmissible among humans - but this seems like a bad idea.
Inflammatory Genes Link Obesity, Diabetes to Pancreatic Cancer
Shared inflammatory genes are active in both pancreatic cancer and metabolic diseases like obesity and diabetes, providing insight into why metabolic conditions worsen cancer outcomes and highlighting potential targets for improved prediction and treatment. cancerbiology
Early Quasar Winds Quench Star Formation in Young Galaxies
Observations indicate that powerful winds from early quasars expelled vast amounts of gas from their host galaxies, likely shutting down star formation and influencing the evolution of massive galaxies soon after the Big Bang. astrophysics
Natural Playgrounds Strengthen Children’s Immune Systems
Finland replaced artificial playground surfaces with natural elements like mud and soil, and the results surprised even researchers… … Children playing in these "rewilded" environments showed significant improvements in their immune systems, including reduced pathogens and increased immune-regulating T cells, highlighting...
Six Players, No Controls: Limited Microbiome Insight
Six (yes, 6) college football players with non-concussive head injury (NHI) and changes in their gut microbiome. No controls. What can you conclude from this? Not this: "Our results provide strong evidence for a link between NHIs and changes in the...
Meta‑analysis Finds No Benefit to Extra DHA
I am sometimes asked why @getkion fish oil does NOT have “extra” DHA…fact is, a recent meta-analysis of 96 randomized controlled trials at https://t.co/YZMb5dar8P showed no clear advantage of decreasing the EPA:DHA ratio…learn more about the formula here: https://t.co/8REbBJKoBJ
Why I’m Passionate About Space Science – Free Post
I wrote about why I space science in this free post on @cosmoquest.org 's patreon.
Climate Science Isn’t Uncertain—Basics Remain Clear
Science is never truly settled… right? 👋 I’m a climate scientist, & today I'm addressing trolls that try to make climate science sound uncertain. Yes, science is always learning more. That doesn't mean we are confused about the basics. You can argue...
Scaling Climate Health Tools Yields Massive Payoffs
We have the tools to anticipate and prevent climate-related public health crises. Our task now is to scale them. A new report from @WRIClimate shows the payoffs if we do: https://t.co/1UK253k1x7
IBM Quantum Simulates 13,635‑Atom Protein, Hitting HPC Limits
And @JMChow shares how @ClevelandClinic on an @IBM quantum system has reached the limits of HPC - 13635 atoms in a protein molecule. #IBMThink https://t.co/PdyO2n1ZIz
Young‑Adult Work Activity May Shield Against Dementia
Physical activity across the life course and neural biomarkers 💡"PA done as part of one's job or schooling during young adulthood, such as standing and walking, may be protective against dementia later in life." https://t.co/tGarY3gUA2
Gut Microbiome Resilience: Key to Longevity
Gut Microbiota Resilience and Environmental Stressors: A Hidden Key to Lifespan Optimization? "...The review also outlines practical ways to bolster resilience: fiber-rich, plant-based and fermented foods; targeted probiotics, prebiotics/synbiotics, and (in special cases) fecal microbiota transplantation; regular physical activity; good sleep...
Peptides Boost Hormones, Yet Trigger Serious Metabolic Side Effects
People mistakenly believe peptides are only good. Peptides can be bad, too. They can cause adverse effects. Some dangerous. I did a peptide experiment and measured its effects in my body. The results are complicated. I tried a peptide called CJC-1295....
Evolvable AI May Outpace Life, Evade Control
A new study warns evolvable AI systems could adapt and reproduce faster than any biological species, escaping human control entirely. https://t.co/7Azzs5dsRB
Seed Oils Aren't Inflammatory; Cooking Methods Are
New study shows that seed oils DON'T really cause inflammation: https://t.co/kxEXYt2ghe This is something I've mentioned on my podcast a few times... ...it's not the oils per se. It's frying them, eating them in ultraprocessed foods/with fast food, etc. Guilt by association....
Heroic Psilocybin Dose Dramatically Rewires Brain Connectivity
“Scientists gave people a “heroic” dose of psilocybin and then looked at their brain. Here’s what happened” https://t.co/M9FjCRGNNq
Microplastics Linked to Neurodegenerative Disease Risk
New research reveals a concerning connection between microplastics and neurodegenerative diseases. As we strive for better health, it's crucial to understand the impact of our environment on our well-being. Dive into the details and learn how to protect yourself and...
Only 90% of Consumed Calories Are Truly Metabolizable
“Digestible energy intake” tells you the difference between how many calories you ingest and how many you actually burn. A typical number: 90%. “Digestible and Metabolizable Energy Intake in Humans: a Systematic Review,” Yoshimura et al, Advances in Nutrition, 2026.
Uterus: From Pear to Watermelon, Generates 90‑lb Contractions
Your uterus is the size of a pear when you're not pregnant. By the third trimester, it grows to the size of a watermelon. When you're in labor, it can generate up to 90lbs of force per contraction. It also contracts...