Only 90% of Consumed Calories Are Truly Metabolizable
“Digestible energy intake” tells you the difference between how many calories you ingest and how many you actually burn. A typical number: 90%. “Digestible and Metabolizable Energy Intake in Humans: a Systematic Review,” Yoshimura et al, Advances in Nutrition, 2026.
Uterus: From Pear to Watermelon, Generates 90‑lb Contractions
Your uterus is the size of a pear when you're not pregnant. By the third trimester, it grows to the size of a watermelon. When you're in labor, it can generate up to 90lbs of force per contraction. It also contracts...
Oracle and ACRN Health Launch AI-Driven Research in Africa
This collaboration between Oracle Life Sciences and the @acrnhealth is a significant step in delivering modern, AI-driven, patient-centric research and scientific breakthroughs in Africa. https://t.co/Z26aK7wRxW
Rice Professor Calls for Open Abiogenesis Research
Did you see this?👇 Rice Professor Demands Transparency on Origin of Life Chemistry #abiogenesis #science #chemistry https://t.co/37lnNnx0Zo https://t.co/7JCYBRtXbI
MIT's Mirai AI Spots Breast Cancer Years Early
The story of Mirai, MIT's AI model that can detect breast cancer years before humans do: https://t.co/5YbCFJRKUK https://t.co/3NLCkWaAqR
Scientists Remove Essential Amino Acid, Redefining Life's Code
All Life Uses 20 Amino Acids. Scientists Just Deleted One in Bacteria The synthetic bacteria push the limits of life and could open the door to designer proteins and new medicines https://t.co/mVZrQ0z7vz https://t.co/zFzSpnrk6h
Radiologists Draft Consent for Unproven Whole-Body MRI Screening
At @JAMA_current today, 2 radiologists publish what should be the consent form for a total body MRI in healthy people Note: "no major medical society recommends whole-body MRI screening in the general population because it is unproven, and the harms likely...
New NIST Study Shows Gravitational Constant Still Uncertain
A new experiment deepens the physics mystery over “big G” Last month, a NIST team published a 10-year study to measure "big G," the gravitational constant. It didn't settle the debate, but rather revealed what everyone should consider. https://t.co/TQOhe14uVB
Dark Proteome Research Redefines Human Disease Understanding
This, from @MeganMolteni, is frickin' cool. "How a global effort to explore the ‘dark proteome’ is upending our understanding of human disease." I remember when everyone was shocked that there were only 30,000 protein-coding genes found by the Human Genome Project. This...
Pill GLP‑1 Drugs Activate Amygdala Reward Circuit, Not Hypothalamus
Discovery of a new brain reward circuit in the amygdala for small molecule (pill) GLP-1 drug effect, unlike the injectables (hypothalamus), as shown in mice https://t.co/3lkfxROh5Z
Blood Test Now Gauges Tumor Microenvironment Non‑invasively
We've known how important the tumor microenvironment is for cancer progression and treatment, but we never had a non-invasive blood test to assess it. Today, as reported @nature, one has been discovered https://t.co/rDaF5YUwTq
B‑cell Cancer Patients Face Higher Severe COVID‑19 Risk
Patients recently treated for B-lymphoid malignancies show increased risk of severe COVID-19: a #CCC19 registry analysis [Mar 9, 2022] @rubinstein_md et al. @mtmdphd @COVID19nCCC @BCD_AACR https://t.co/IMEbvgZafi #COVID19nCancer #COVID19 #bmtsm #leusm #lymsm #mmsm #mpnsm https://t.co/mKoZFJnNBQ
AI MRI Links Body Composition to Longevity
As a medical school professor and radiologist, this is one of the most important imaging-meets-longevity studies of the year. AI-driven whole-body MRI body composition in 66,608 adults (UK Biobank + German National Cohort, mean age 57.7, mean BMI 26.2), published in...
Hantavirus Spread Undetected on Cruise Ship for Weeks
How a deadly hantavirus outbreak unfolded on a cruise ship for weeks before it was identified https://t.co/HX5mypL6Hr
Exercise Boosts Mood: Data From 8,000 Participants
Physical activity and affective well being (AWB): individual level data from over 8,000 participants with accelerometers and >330,000 AWB ratings. Figure shows AWB metrics before and after physical activity. @NatureHumBehav https://t.co/BNkZVZf3j4 https://t.co/eAB1UMPqNH
New Air‑filled Chambers Found Inside Menkaure Pyramid
Secret chambers have been discovered in a Giza pyramid Researchers from Cairo University and the Technical University of Munich (TUM) have located two air-filled spaces within Giza’s Menkaure pyramid that hint at a possible secret entrance. The Menkaure pyramid is the...
Bioinformatics Advances Faster than You Can Keep Up
🧵 You’re not behind in bioinformatics. The field just evolves faster than anyone can follow. 1/ It’s not you. Bioinformatics evolves too fast. And not just from new algorithms— But from how fast technology itself changes. https://t.co/5UvXR7l1yX
Harvard-Backed Trials Still Face Skeptical Disagreement
Have a team at Harvard Medical School, and drug pipeline in human trials, and scientific papers dating back to 2008 challenging that assumption No - I don’t agree 🤣
More Steps Can Counteract Sedentary Disease Risk
As a medical school professor, the most actionable longevity finding of April 2026 came from 15,327 adults in the All of Us Research Program, published in Nature Communications. Researchers tracked Fitbit data over years (millions of person-days). They asked: can extra...
Early Clues Showed Airborne Human-to-Human Andes Transmission
Important that the sequencing was done to confirm Andes (h2h strain), of course, but there were obvious early signals that this was h2h and airborne before that: --> index patient got it before boarding, second patient got it *weeks* later. Now...
Self‑Destructing Plastic Degrades Completely in Two Weeks
Plastic pollution doesn’t seem to be getting better. But what if we could engineer plastics to get rid of themselves? A team of scientists in China recently demonstrated this somewhat comically idealistic solution, reporting their findings in a recent paper published in...
Microsoft May Drop Ambitious Clean‑energy Goal for Data Centers
Microsoft Corp. may shelve one of the industry’s most ambitious clean-energy targets as it tries to remove hurdles that could hold it back in the race to power data centers, according to people with knowledge of the matter. https://t.co/V2xpfWIiLr
Atlantic Current Slowdown Threatens Climate and Weather Patterns
A key Atlantic current is weakening. Here’s why it matters. | DW News (with an interview with me). https://t.co/e2m3LlEapg
Higher Protein May Offset Low‑energy Availability Effects
Does protein intake influence low-energy availability symptoms?🪫 This new study recruited healthy active females (n = 9) and males (n= 10) to complete 3 x 5-day dietary conditions 1️⃣ Adequate energy availability (AEA: 45 kcal/kgFFM/day) 2️⃣ Low energy availability (LEA: 15...
Perspective Shifts: Still Looks Hide Rapid Motion
Physics just exposed how easily our eyes can fool us. A drone looks completely still inside a moving car. But here is the twist: It may look frozen in the air, yet it is actually moving at nearly 100 km/h. Relative to the car,...
Klotho Deficiency Heightens Stroke Risk in Aging
The antiaging protein Klotho is a key factor in susceptibility to cerebral ischemia Highlights: • Klotho deficiency links aging to higher vulnerability to ischemic stroke • Klotho deficiency increases inflammation and disrupts the blood–brain barrier. • Loss of Klotho intensifies ischemia-induced oxidative and ER...
Bird Flu Deadly, but Far Less Contagious Than
Y'all, let me help you feel better by making you feel comparatively worse. The WHO has tracked 13 human bird flu infections so far this year. In February, it wiped out 7.4 million chickens in PA alone. Estimates for how many...
Swarm Satellites Distinguish Space Weather, Boost Early Warnings
Swarm satellites are enabling precise differentiation between electromagnetic signals from space weather and natural hazards, advancing early-warning systems and improving the resilience of critical infrastructure. spaceweather
High Solar Activity Accelerates Low‑Earth‑Orbit Debris Decay
Space debris in low Earth orbit descends more rapidly when solar activity exceeds two-thirds of its peak, altering satellite collision risk and requiring updated mission planning as solar cycles intensify atmospheric drag. spaceweather
Direct Protein Reading Platform Ends Proteomics Blind Spot
🐠 Everything we know about biology has been built on an incomplete picture. DNA tells us what a cell might do. Proteins tell us what it’s actually doing. Pumpkinseed announced their $20M Series A today (led by Future Ventures and NfX)...
Immunology: From “Solved” To Discovering Diverse Cell Roles
“In 1960, immunologists essentially said the field was basically solved. A few years later, people figured out there were different types of immune cells doing totally different things.” ~@salonium
New Framework Separates True Aging Effects From Study Bias
Mitigating the Hawthorne effect in aging “This Comment proposes a methodological framework to distinguish true biological aging modulation from the confounding effects of study participation.” https://t.co/h9Z2qiFzwv https://t.co/KdnJfSJzhe
Young Gut Microbes Fail
Gut microbiota transplantation from young adult mice fails to restore low bone and muscle mass in old mice https://t.co/BXKJo3Ovi6 https://t.co/JZ3O4BqXd6
Venter's Brilliance Shines at 80 Despite NIH Snub
J. Craig Venter, at 80 here (just before his death), with a high cognitive capacity on full display Also note the issues with the NIH not funding his grant to sequence the first human genome https://t.co/YhDkLjwCBt
Reduced-Gravity CPR Simulator Shows Unique Hemodynamics for Space Resuscitation
A high-fidelity CPR simulator replicates blood flow in reduced gravity, revealing distinct hemodynamic responses compared to Earth conditions and offering new insights for resuscitation strategies during space missions. spacemedicine
13‑Year Study Redefines Colonoscopy’s Population‑Level Impact
Colonoscopy, cancer prevention, and the new arithmetic of benefit - @TheLancet “The study's 13-year results compel a recalibration of what colonoscopy can—and cannot—achieve at the population level. https://t.co/vDOv0cSkjY
Space Mission Lessons: Risk, Teamwork, Endurance Revealed
Thrilled to be bringing my live talk “The Sky is Not the Limit: Lessons from a Year in Space” to Australia this November. I’ll take audiences behind the scenes of my 143-million-mile mission- the risks, teamwork, and endurance that made...
Anemia Raises Alzheimer Biomarkers and Dementia Risk in Seniors
In a large study of older adults, anemia was linked to higher levels of blood biomarkers associated with Alzheimer’s disease, neurodegeneration, and brain inflammation, as well as a significantly increased risk of developing dementia over time. https://t.co/cnUbvkidIO
Aged Male Mice Stay Glucose Tolerant Despite Obesity
Aged Male Mice Remain Glucose Tolerant Despite Increased Energy Storage Efficiency Favoring Diet-Induced Obesity https://t.co/PzeRMKqvKw https://t.co/mUihjmGsSG
Brain IGF-1 Shields Male Mice From Age‑Related Decline
Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice https://t.co/7U25aLdLFv
Plant-Inspired Robot Grips Objects Gently
This Plant-Inspired #Robot Handles Objects with Care by @MIT #Robotics #Engineering #ArtificialIntelligence #Innovation #Technology https://t.co/IpDoXtRMOa
Nastent Nasal Insert Outperforms CPAP in Compliance
Your doctor will not tell you this. Most CPAP patients hate it and abandon it within months. Their oxygen crashes at night. Their mitochondria suffer. Their glymphatic system cannot clear amyloid beta. A clinical trial just completed on Nastent. It is...
Blocking IGF1 Senescence Reverses Hair Follicle Aging
Targeting IGF1‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging - Wang - 2025 - Aging Cell - Wiley Online Library https://t.co/LwbNFih66G
5-MeO-DMT Boosts Brain Complexity, Rekindles Childlike Curiosity
My brain became 40% more child-like in 3 minutes. This is what it felt like. Me: “What question do we ask them next?” My daughter: “Are they scared of the dark too?” My six year old daughter and I were...
Beihang Unveils 2 Cm Microbot Achieving Ultrafast Untethered Speed
Beihang University Unveils 2 cm Microbot with Ultrafast Untethered Speed via @WevolverApp #AI #Robotics #MachineLearning #ArtificialIntelligence https://t.co/BN6RijA61e
When $160M Incomes Become Normal, Civilizations Vanish
How long do civilizations last? The Drake Equation, Bel‑Air mansions for everyone, & the Great Filter; or, where is everybody when $160 million a year incomes are normal? (Behind the paywall, at least initially, because I am not yet happy...
PhD Defense Takes Precedence Over Artemis Image Talk
Y’all I want to talk about all the new Artemis images that just dropped but I am defending my PhD tomorrow so that’s gonna have to wait 😅
Airborne COVID Transmission Confirmed on Diamond Princess
Reupping this piece from NYT when they covered our modeling of Covid transmission on the Diamond Princess cruise ship that demonstrated it was spread person-to-person through the air, when people said that couldn’t possibly be happening… https://t.co/pB5qyRFC5u https://t.co/QkW8sr7LVW
IPCC Scenario Panel Drops Alarmist RCP8.5 and Peers
A rare piece of good news from the international climate bureaucracy: The committee that developed the GHG emissions scenarios used in the IPCC's climate models has removed the three most unrealistic and alarmist scenarios: RCP8.5, SSP5-8.5, and SSP3-7.0. These scenarios, especially RCP8.5,...
US Emissions Falling, but Net‑zero Delayed to 2100
US emissions will likely continue to decline over the next decade even with the partial repeal of the IRA (and the passage of the OBBBA). But the rate of decline puts us on track to get to net zero emissions...