CD47 Blocks Mouse but Not Human Macrophage Phagocytosis
"the classic “don’t eat me” signal CD47 has minimal impact on human macrophage phagocytosis. By contrast, CD47 strongly suppressed mouse macrophage phagocytosis."
Exercise Decline Accelerates Aging—New Review Offers Solutions
We now exercise five times less than we did 100 years ago. Our lifestyles are accelerating aging New review @Cell_Metabolism how to counter it https://t.co/rmb527oP0Y
Japan Funds South Africa Ammonia‑coal Tech to Cut Emissions
Japan is seeking to boost its presennce in South Africa by offering an energy transition loan and a technology that allows ammonia to be blended with coal to reduce power plant emissions https://t.co/BC6XVYmL82
Embryos Begin Female; Male Development Requires Y Gene
The female form is the human default. For the first 7 to 8 weeks of pregnancy, every embryo looks the same. They all start with a bipotential gonad and both sets of reproductive ducts. Around week 7, if a Y chromosome...
Roscosmos Completes Crew Capsule Processing Stand at Vostochny
Last month, Roskosmos completed processing stand for the crew capsule of the PTK (Orel) new-generation spacecraft, which the ship's 2nd worksite in Vostochny spaceport. Similar installations are planned for PTK's other components. CONTEXT: https://t.co/a3ipLmZ6e9 https://t.co/aQzomFk80C
Time‑Restricted Eating Counteracts Hypoxia‑Induced Glucose Dysregulation
Time-restricted eating improves intermittent hypoxia-induced dysglycemia "In IH, TRE mitigates adverse hypoxic effects on glucose homeostasis, via improvements in pancreatic insulin secretion. Some beneficial glycemic effects of TRE are accentuated in IH. TRE may represent a novel therapeutic strategy in OSA" https://t.co/SQgSGnX6Ay
Moderate Training Boosts Brain Metabolism; HIIT Adds Benefits
High-intensity interval and moderate-intensity continuous training on cerebral energy metabolism in older rats "These findings suggest that MICT is the preferred regimen for enhancing cerebral metabolic function and neurovascular adaptation, while HIIT serves as a complementary strategy to involve other brain...
Sleep Deprivation Leads to Major Muscle Atrophy in Rodents
Lack of sleep directly produces substantial muscular atrophy in rodent models (although it is not always easy to disentangle the effects of stress and sleep loss in such cases). https://t.co/ah019I6zNw
CSAIL Revives 80s Three‑s
In the '80s, future MIT prof. Bill Freeman envisioned a three-sided zipper that could switch items between soft & rigid states. Last year, CSAIL revived his idea w/an automated design tool. It 3D prints "Y-zippers" that snap gear, robots, & art...
RDL Generates More Hamstring Force Than Max Sprint
Stop underloading your hamstrings in the gym, the Romanian Deadlift (RDL) crushes sprint-level demands. New BJSM study (2026) used MRI + EMG + 3D motion capture + musculoskeletal modelling to measure actual muscle force & stretch in the hamstrings (BFlh, semimembranosus,...
Chemical Reprogramming Triggers Toxic Lipid Droplets In Vivo
https://t.co/F6dZ4lFcUZ problem is that most groups don't publish negative results here's a recent paper from @gladyshev_lab showing that chemical reprogramming (yes, different thank OSKM) causes lipid droplet formation and significant in vivo toxicity
Scientists Edge Closer to Mapping Psychedelic Brain Effects
Science gets closer to understanding how a psychedelic trip changes the brain https://t.co/XWKXo1TIAL via @nbcnews
Orexin Therapies Unlock New Horizons Beyond Narcolepsy
Orexin drugs for narcolepsy and more. Listen to Richard Pops @popsalks discuss the emerging opportunity, and his 35-year-career, on The Long Run. Sponsored by @AlphaSenseInc & Dash Bio. https://t.co/Qr6oJ8AwzB
New Brain Pathway Protects Women From Parkinson’s Progression
A newly identified brain pathway strengthens dopamine-producing neurons and slows Parkinson’s progression, but this protective effect was observed only in females, highlighting the importance of sex-specific approaches in future therapies. neuroscience
Laser‑threshold Triggers Self‑generated Magnetic Fields in Fusion Plasma
Simulations show that when laser intensity crosses a specific threshold, rapidly expanding fusion plasmas can self-generate strong magnetic fields, fundamentally altering heat flow and plasma behavior in direct-drive inertial fusion systems. fusionenergy
Colored Microplastics Absorb Sunlight, Boost Warming Beyond Estimates
Airborne colored microplastics absorb significantly more sunlight than uncolored particles, trapping nearly one-fifth as much heat as soot and intensifying global warming beyond previous estimates. microplastics
Single 25 Mg Psilocybin Dose Triggers Month-Long Brain Changes
A single 25 mg dose of psilocybin leads to brain structural changes that were seen at 1 month. From a cross-over study of 28 healthy volunteers, no prior psychedelic, who also were also assessed after 1 mg. Behavioral results in...
Russia's Ekspress‑AMU4 Launch Pushed to 2028
Ekspress-AMU4, Russia's first civilian geostationary communications satellite to be developed in isolation from the West, completed acoustic tests, but its launch just slipped from 2026 to 2028 due to components' delays... https://t.co/Mz5ys2bFrq
Large AI Models Gain Spatial Intelligence for Complex Robot Manipulation
A new Science #Robotics study endows large AI models with spatial intelligence, enabling them to guide robots through complex manipulation tasks such as orienting objects towards a camera or rearranging spoons to align them perfectly. https://t.co/HtYuOHGgTd https://t.co/5pEPLQOHeM
From Telecom to Longevity: Big Science Aging Talk
TODAY @ 10AM PT: LBF Conversation with Todd White @DToddWhite (Director @ Thalion Initiative). We'll be discussing Big Science for Aging Biology, fundraising, and his founder story pivoting from a career in telecom to longevity biotech. 👉 RSVP: https://t.co/UJP8xs8nrc
MRI Body Composition Predicts Diabetes, Heart Events, Mortality
Body composition from MRI of 66,000 people was linked to diabetes, major cardiovascular events, and all-cause mortality @radiology_rsna https://t.co/KUkMppvorA https://t.co/FdyHjpWqW1
White House Reviews SEC Plan to Scrap Climate Disclosures
The White House is reviewing a proposal from the Securities and Exchange Commission to formally end Biden-era climate disclosure rules for publicly-traded companies. https://t.co/Xw3zksqcOJ
Multivitamins Show No Overall BP Benefit, Help Low‑Diet Individuals
Long-Term Effect of Multivitamin Supplementation on Incident Self-Reported Hypertension and Blood Pressure Changes in the COSMOS Trial "MVM supplementation versus placebo did not reduce hypertension incidence or lower BP overall. Exploratory analyses showed greater reduction in hypertension risk and BP changes...
ReBASE Reveals Climate’s Impact on Extreme Events
How would observed extreme events differ in warmer or cooler climates? First results from the ReBASE (Reanalysis-Based Attribution and Storylines of Extremes) project are now available, with analysis by Rhidian Thomas & Vikki Thompson. #EGU26 Poster: https://t.co/L5JIubN8QW https://t.co/2guqTmSYQU
Genetic Variant Determines Individual GLP‑1 Drug Response
As a medical school professor, I get asked why GLP-1 drugs work miracles for some and barely budge for others. A new Nature paper from 23andMe gives part of the answer: your genes. Researchers ran a genome-wide association study in 27,885...
Gallium Needle Softens at Body Heat, Boosts Injection Safety
KAIST Develops Gallium Needle That Softens at Body Temperature for Safer Injections by @tweetciiiim #MedTech #HealthTech #Tech #TechForGood https://t.co/g8iTdzNeF9
RAGE Gene Therapy Cuts Inflammation, Not Lifespan
It's a gene therapy that targets the RAGE pathway (Receptor for Advanced Glycation End-Products) that mediates inflammation and oxidative stress signaling. So far, the mice data doesn't show significant longevity benefits and mostly reduced inflammation and vascular stiffness and kidney damage. On...
Superintelligent AI Not Required to Improve Cancer Outcomes
Big tech companies claim superintelligent AI could one day cure cancer. But do we really need smarter AI to change cancer outcomes? https://spectrum.ieee.org/can-ai-cure-cancer-javorsky?share_id=9456123
Science Drafts the Brain’s First User Manual
Your brain didn’t come with a user manual, but science is finally writing one. 🧠 Credit: Tay SW, Ryan P, Ryan CA. Systems 1 and 2 thinking processes and cognitive reflection testing in medical students. Can Med Educ J. 2016 Oct...
Male‑dominant Dementia Risks Highlighted in 2024 Lancet Report
Broadening dementia risk models: building on the 2024 Lancet Commission report for a more inclusive global framework Your dementia risk profile may differ by sex. Which risk factors matter most for you? 🤔👇👨⚕️ "The 2024 report identifies 14 modifiable risk factors for...
Myqorzo ACACIA Study Achieves Dual Primary Endpoint Success
$CYTK Here we go! Myqorzo ACACIA study results in nHCM --> BOTH co-primary endpoints hit with statistical significance. There may be debate about magnitude of improvements for Myqorzo via KCCQ-CSS and peak V02. But, if you were dreaming for a...
Experience a Starlink Satellite's Full Orbit Firsthand
Here you can follow a Starlink satellite through an entire orbit… …in a first person view. 🤩
Germany Launches €5 Bn Auction for Industrial Decarbonisation
Germany kicks off an auction to offer up to €5 billion to help heavy industries cut their carbon emissions https://t.co/2MKA0UuXtz
Musk Must Deliver on Lifetime Mars Colonization Promise
This only means that @elonmusk must deliver on his promise to take humans to #Mars in this lifetime ✨ https://t.co/zMvgA9zBw4 #ColonizeMars #MissionMars
Coauthoring Landmark EU Study on Longevity Research
Very proud to be one of the authors of this important paper to support longevity research in the European Union, with many of the leading experts in our region. https://t.co/RpsdF5zmXD #healthylongevity #ageing #longevitydividend #geroscience #healthpolicy https://t.co/HRCphTuY3Q
Astaxanthin's Lifespan Boost Hinges on Dose and Timing
Astaxanthin was tested for lifespan in mice. In 2023, it increased lifespan by ~12% in male mice But a new 2026 study found no effect. The big difference: dose and timing. Full video breakdown: https://t.co/6r7rqMc8jw https://t.co/Lm8ApCG64t
Geothermal Power: Mars' Viable Renewable Energy Option
Can clean, renewable energy sources be used on Mars? Mars is a cold, barren planet far from the sun, and with little atmosphere and no flowing water. If people were to live there, could they obtain their energy from clean, renewable...
New Method Dramatically Cuts Inter‑animal Variability
"Second, and relatedly, this method dramatically attenuates inter-animal variability." Good time to resurface an old figure: https://t.co/VgRlZrurPE
New Trial Compares Dara‑Bor‑Dex vs Cy‑Bor‑Dex in MM with LCCN
EAA241 - Ph 2 RCT Dara-Bor-Dex vs Cy-Bor-Dex in the treatment of Newly Diagnosed Multiple Myeloma with Light Chain Cast Nephropathy (LCCN) [Study activated 8/11/25] @keruakous https://t.co/1NgvVZ3fTA #NCT07085728 #mmsm @eaonc https://t.co/Jrh4teOxUK
Daratumumab Boosts Revlimid Efficacy in Smoldering Myeloma
#EAonc EAA173 - Daratumumab to Enhance Therapeutic Effectiveness of Revlimid in Smoldering Myeloma (DETER-SMM) - PI: @nsc_natalie https://t.co/VtBMJUjI5X Activated: Apr 30, 2019 #mmsm @eaonc #NCT03937635 @VincentRK @mweissmdphd https://t.co/oQzEYsPoU4
Phase 3 Trial
.@SWOG S2213 Ph3 RCT Dara-VC Induction Followed by ASCT or Dara-VCD Consolidation & Daratumumab Maintenance in Pts w/ Newly Diagnosed AL Amyloidosis [Activated: 12/1/23] https://t.co/OizUfJCc2c #mmsm #bmtsm https://t.co/zWMK1RfCFW
Sunlight Boosts Heart Health Beyond Vitamin D
Sunlight: Time for a Rethink? 🤔 “Growing evidence shows that sunlight has health benefits through vitamin D–independent pathways, such as photomobilization of nitric oxide from cutaneous stores with reduction in cardiovascular morbidity. Sunlight has important systemic health benefit as well as...
Explore the Diverse Types of Cosmic Black Holes
Do you know your black holes? Watch to find out what different types of black holes there are, and we think there are, in the universe. How many did you know?
New Climate Dashboard Offers Daily Probabilistic ENSO Forecast
I've updated my Climate Dashboard to provide a daily updating probabilistic ENSO forecast similar to NOAA's, using 637 ensemble members across 13 different models (weighted by unique model). Here are the current results using the Oceanic Nino Index (ONI) https://t.co/MnveT7pFLN
Gene Therapy Targets Childhood Blindness by Fixing Retinal Gene
Jean Bennett and Albert Maguire developed a gene therapy approach to correct a gene in the retina to treat childhood blindness. https://t.co/WJ99qvcUT1
Starship and SLS Can Achieve 4K Orbit without Extra Hardware
Some interesting notes besides the amazing 4K streaming from orbit (YES PLEASE), the inclination and altitude mentioned tells us two things. 1. Starship could do this from Starbase, so it wouldn't require 39A pad to be operational. 2. SLS could do...
Autonomous Lab Discovers Brighter Lead‑Free Nanoplatelets
An autonomous laboratory rapidly identified brighter, lead-free light-emitting nanoplatelets by autonomously testing and optimizing synthesis recipes, offering a scalable approach to accelerate safer nanomaterial discovery for optoelectronic applications. nanotechnology
Berlin Lakes Harbor Widespread Antibiotic Resistance, Urban Waters Highest
Antibiotic-resistant bacteria and their genes are widespread in Berlin-area lakes, with urban waters and wastewater treatment plant effluent showing the highest diversity and load, but resistant genes also persist in rural lake sediments. antibioticresistance
Ocean Wave Power Enables Low‑Cost Floating AI Data Centers
I'm delighted to be a small part of this. The oceans are an incredible untapped resource for energy that can power AI. The most intense wave energy is thousands of miles from human settlements, but can power floating data centers...
Quantum Supremacy Already Here—Even on Amazon Prime
next time someone asks me “when will we achieve quantum supremacy” i’ll just be like duh it already happened, it’s even on amazon prime https://t.co/uh9gAhiB9B