Targeted mRNA Nanoparticles Halt Lung Tumors and Cachexia
Follistatin mRNA delivered via targeted lipid nanoparticles enables a dual therapeutic effect by simultaneously suppressing lung tumor growth and preventing cancer-associated muscle wasting (cachexia). https://t.co/56fCFZU0vk
Aging Opens Chromatin, Altering Cell Behavior
The researchers then looked into the changes in the old cells that might explain such pronounced differences in behavior compared with the young cells. Liao Says "It seems as though chromatin opens up with age, so to speak." https://t.co/1kdRDunTea
Arsenic‑Framework Boosts Rhodium Hydroformylation Activity and Selectivity
A new arsenic-lined crystalline framework stabilizes rhodium catalysts, enhancing both activity and selectivity in hydroformylation while minimizing arsenic leaching, demonstrating a practical route for advanced catalytic performance. chemistry
Annealing Boosts Efficiency of Copper-Plated Heterojunction Cells
The impact of annealing on copper-plated heterojunction solar cells #energysky -- via pv magazine global: https://t.co/DM37J5KaRF https://t.co/POFNPoUMby
Higher Albumin Levels Linked to Longer Lifespan
High albumin is associated with longevity Association between age and malnutrition in oldest-old and centenarian populations https://t.co/0denO96lEh
Healthy Diet Cuts Mortality Risk Among Chinese Elderly
Association between Dietary Patterns and All-Cause Mortality in the Chinese Old: Analysis of the Chinese Longitudinal Healthy Longevity Survey Cohort https://t.co/4FoNf4WnRt #mdpinutrients
Artemis Highlights NASA’s Evolving Mission Landscape
This post is now a newsletter, with hyperlinked sources + some thoughts on Artemis and the state of NASA https://ayanaelizabeth.substack.com/p/earth-is-blue-thank-you-artemis
Garlic Intake Linked to Lower Mortality in Chinese Elders
Garlic Consumption and All-Cause Mortality among Chinese Oldest-Old Individuals: A Population-Based Cohort Study https://t.co/Oda8CifdOX #mdpinutrients
IPSC Therapies Succeed; In‑vivo Reprogramming Remains Hype
your regular reminder that Yamanaka factor-driven production of iPSCs is already producing real medicine (eg dopaminergic neural progenitor for Parkinson's, cardiomyocyte sheets for heart failure & more) iPSC tech is not done in vivo... ppl isolate the well behaved cells away...
Daily Evoked Gamma Therapy Shows Safety and Cognitive Benefit
Safety, tolerability, and efficacy estimate of evoked gamma oscillation in mild to moderate Alzheimer’s disease 👉 “Our results demonstrate that 1-h daily treatment with [CogTx-001] was safe and well-tolerated and demonstrated potential clinical benefits in mild to moderate AD.” 🔘 Participants underwent...
Compact X‑ray Telescope Resolves 3.5 Mm at One Kilometer
A new high-resolution X-ray telescope, developed with advanced mirror technology, can distinguish objects just 3.5 mm wide from a kilometer away, marking a significant step toward compact, high-precision space-based X-ray astronomy. spaceinnovation
Uta Frith: Autism Isn't a Spectrum
There is no autism spectrum, says expert (esteemed cognitive scientist Uta Frith) who pioneered our understanding of the cognitive deficits underlying autism. https://t.co/a5e8jZzUbF
First Human Orbital Flight Marks 65-Year Milestone
65 YEARS AGO TODAY: The first human reaches Earth's orbit FULL STORY (and my reconstruction of the event): https://t.co/l1fyUe3ztw https://t.co/KqZ4ndMNXk
Exhausted Yet Relieved, Fans Crave Faster Moon Missions
Anyone else feeling the duality of absolute exhaustion and relief that Artemis 2 is over, and also a sadness in the absence of such an incredible mission to continue captivating the world? I hope @rookisaacman’s plan to launch SLS every...
Dementia Poised as 3rd Leading Death Cause by 204
ADI leads new research forecasting dementia to become the 3rd leading cause of death by 2040 Additionally, the number of people living with dementia "is set to almost triple in number by 2050, to 139 million." https://t.co/WSm2Rhp3ju
Drugs May Slow, but Not Fully Reverse Aging
Just like we can't turn a human into a naked mole rat with drugs (requires too many specific molecular changes), I don't think we will fully reverse ageing pharmacologically. We may be able to slow human ageing with drugs, but reversing...
Dream Realized: Artemis 2 Astronauts Celebrate Moon Mission
Getting to cover This mission has been a dream. Thanks most to this crew. https://www.space.com/space-exploration/artemis/the-most-special-thing-that-will-ever-happen-in-my-life-artemis-2-astronauts-describe-their-epic-moon-mission
Robotics and BCI: Breakthroughs Shaping Humanity’s Future
keep an eye on robotics and BCI, both are making breakthroughs which will forever shape the future of humanity
Genetics Shape Specific Cognitive Skills, Not Just General IQ
An accessible explanation of the new study on by Steve Stewart-Williams @SteveStuWill here | Beyond General Intelligence: The Genetics of Specific Cognitive Abilities https://t.co/uRnhKsuJQE
Specific Cognitive Skills Proven Heritable in New Meta‑Analysis
Important new finding: For decades there's been abundant evidence for the existence, importance, & heritability of "general intelligence" (despite massive denial in journalism, ed schools, and among intellectual-cultural elites). That is: if you're above average in verbal skills, you're likelier...
Total Protein, Not Timing, Drives Muscle Growth
Some 20+ years ago, when I was studying exercise science, nutrient timing was viewed as a cornerstone of muscle growth. We were taught about the so-called “anabolic window,” which suggested that protein needed to be consumed within ~45 minutes after...
A Decade of DNA Innovation Powers AI‑Biology Convergence
Ten years ago, Emily Leproust had an idea to rewrite how DNA gets made. Most people thought it wouldn't work. Today, Twist Bioscience is the infrastructure layer for biotech and pharma worldwide. At SynBioBeta 2026, she's on the main stage with John...
Rare Diseases Need Molecular Surgery, Not Drug Barriers
The turning point for rare diseases, which affect >300 million people around the world. A call to get rid of its many structural obstacles, to consider it as molecular surgery unlike drug treatments gift link: https://t.co/DQ0OZ9tXXc https://t.co/RELCwTr88i
Decade-Old Study Warns of Looming Climate Tipping Point
Despite the title of this @NatureClimate Change commentary, it's not about NATO. It's about one of the worrying potential climate tipping points, and research we (@rahmstorf et al) did about this a decade ago... https://t.co/NOYmx9O3R7
PCA Is Just SVD in Disguise
🧵 PCA is everywhere in bioinformatics—but did you know it’s just SVD in disguise? 1/ If you've done bioinformatics, you've likely used PCA. But did you know Singular Value Decomposition (SVD) is at its core? Let’s break it down. 👇 https://t.co/LGtVfpAEsD
Light Improves Electrical Performance of Low‑Temp 2D Materials
🧪⚛️ Disorder and illumination - how shining light on 2D systems at low temperatures can sometimes dramatically improve electrical properties, including a preprint from this week. https://t.co/86FPuy8rht
Magnetic System Enables Camera‑free Microrobot Navigation
New magnetic system lets microrobots move without cameras or tracking systems by Neetika Walter @IntEngineering Learn more: https://t.co/RM52ul5JG3 #Robotics #Engineering #ArtificialIntelligence #Innovation #Technology https://t.co/ivuzqLBXTl
From Gagarin to Artemis: Humanity’s Space Journey Begins
How it started - how it's going. Yuri Gagarin was the first, 65 years ago today. Artemis 2 crew, safely back from the Moon this week. I salute the bravery, and marvel at what we can do. We've only just...
MIT's Origami Robot Self-Folds Into Multi‑Terrain Machine
MIT’s Self-Folding Origami #Robot Transforms from Flat Sheet to Crawling, Climbing, Swimming Machine by @tweetciiiim #Robotics #MachineLearning #ArtificialIntelligence #ML https://t.co/6UdsasuOcm
Vitamin C May Halt Aging for Just Cents Daily
Vitamin C for Anti-Aging? New 2026 Science (Human and Monkey) 1/2) Could you really slow aging for as little as 6.2 cents per day? Based on new human and primate data published in Cell Metabolism, it might actually be possible. TL;DR: Vitamin...
Rebalancing Autonomic Nervous System May Slow Aging
“We propose that, at the core of aging, there is an imbalance between the SNS and PNS, which provides opportunities for therapeutic intervention.” How? Read more below👇 👨🏻⚕️ 🔎 “Hand-held, non-invasive wellness devices are being deployed in the U.S. military to enhance...
One Blood Test Detects Multiple Cancers and Diseases
Detecting multiple cancers and other diseases from a single blood sample https://t.co/6gjjYY50dm via @medical_xpress #cancer #research
Aging Shares Disease Hallmarks, May Be Treatable
Is aging a disease? These authors reflect: “Disease is commonly defined as an abnormality of bodily structure or function, distinct from direct physical injury (Bulterijs et al., 2015). Whether ageing itself constitutes a disease has long been debated in the fields of...
Heat + Altitude Training Boosts Hemoglobin Mass in Athletes
Heat training augments haemoglobin mass during altitude camp in endurance athletes 🌡️⛰️ This new study recruited 45 cross-country skiers and biathletes (VO2max ~69.1) to one of three 3-week interventions… 1️⃣ Train and reside at moderate altitude with three weekly heat-suit cycling sessions 2️⃣...
Late-Night Meals May Boost Early Cancer Risk via Gut Microbes
Dark side of nocturnal eating: Unraveling the emerging axis between meal timing, gut microbiota, and early-onset cancer risk https://t.co/TLujxFSshs
Self‑healing Living Robot Oscar Blurs Biology and AI
Meet Oscar: The Living #Robot That Can Heal Itself by @pascal_bornet #Robotics #AI #Biotech #Innovation #FutureOfTechnology https://t.co/BLrPrV8X6P
Therapeutic Phlebotomy Restores Bone Marrow, Reverses Aging
Periodic Therapeutic Phlebotomy Mitigates Systemic Aging Phenotypes by Promoting Bone Marrow Function “our work provides preliminary evidence suggesting that periodic therapeutic phlebotomy exerts anti-aging effects by restoring bone marrow function and mitigating aging phenotypes, subsequently driving peripheral blood functional restoration.” 👉 “...
Zero‑G Liquid Storage Set to Revolutionize Space Missions
New Zero-G Liquid Storage System Could Transform Space Missions by @interesting_aIl #SpaceTech #Tech #Technology #EmergingTech #Space https://t.co/RrdFcR9tCT
Safe Cell Reprogramming Restores Identity, Nature Reports
You're confused. Let me explain: My student @Y_Ryan_Lu worked for years to find a SAFE way to reprogram cells so they'd only RE-GAIN identity, not LOSE it, as Prof Yamanaka showed We tried innumerable combos to find the solution Story is @Nature...
Artemis 2: A Bright Gift Amid Growing Negativity
what a gift to humanity drowning in so much negativity lately - Artemis 2 was... We should celebrate our astronauts, engineers, scientists, and all the awesome people at NASA who made it possible.
First FDA‑cleared Humanoid Robot Performs Precise Spine Surgery
World’s First Surgical Humanoid #Robot Achieves FDA-Cleared Precision in Spine Surgery by @StarSnap_1 #MedTech #Healthcare #HealthTech #Tech #TechForGood https://t.co/4HLmX8wb7y
NMN Reverses Ovarian Aging in Mice, Human Trials Needed
DATA REPRODUCED: In old female mice, NMN restores ovarian follicle reserve in 10 days. Optimal dose was 200-500 mg/kg body weight/day. Equivalent to 35-45 in woman years. Clinical trials are needed 🐭🧓 https://t.co/oVeGUZSaQ0
Memory, Not Models, Limits AI-Driven Scientific Discovery
The biggest bottleneck for agentic AI in science isn't the model. It's memory. What was tried. What failed. Why decisions were made. That institutional knowledge lives in scattered notebooks, emails, and people's heads — and most AI tools have no access to...
Summers Are About 20 Days Longer than in 1990.
"Focusing on 1990–2023, the average rate of growth of summer length across all surface types is roughly six days/decade, yielding a ∼20 d longer summer in 2023 than in 1990.” 😳 https://t.co/dezlogLITB
Orion Heat Shield Passes Reentry, Crew Remains Safe
I just had a moment to chat with Lori Glaze, head of the Artemis program, about how the Orion heat shield held up during reentry yesterday. She said they have imagery in hand from divers at the splashdown site, but...
Mussel‑Inspired Phase Separation Happens in Seconds, Defying Theory
Simulations show that mussel-inspired liquid phase separation can occur in seconds when molecules mix via a flux pathway, challenging classical theories and opening new possibilities for rapid, biocompatible adhesives. materialscience
P&G Brings Biotech Ingredients to Mass‑market Consumer Products
P&G doesn't move on new ingredients unless the science is bulletproof and the consumer performance is there. They're moving on biotech. Three R&D leaders from Procter & Gamble are at SynBioBeta 2026 to talk about how bio-derived ingredients are making it into...
DMN's Sender‑receiver Zones Enable Flexible Perception‑memory Switching
The default mode network contains distinct sender and receiver subregions, enabling the brain to flexibly switch between processing external perceptions and guiding memory-based thought. neuroscience
New Path to Affordable Clean Hydrogen Production
Toward cheaper, cleaner hydrogen production by Zach Winn @MIT Learn more: https://t.co/OapBsYTJTo #EmergingTech #Innovation #Tech #Technology https://t.co/a9Png9Yxc4
Basic Sleep, Exercise, Nutrition Trump Extreme Longevity Hacks
After almost a decade studying the biology of aging, I hate to break it to you: Consistency with the basics — sleep, movement, and nutrition — outperforms most extreme protocols when it comes to longevity.