
Dehydration can shrink your brain by over 0.5%, and may be a reason you get a headache. Hydrate to maintain light yellow urine. Also hydrate before an MRI, as dehydration-related small decreases in brain volume can confound MRI-based assessment of brain atrophy which is a biomarker of aging. Dehydration can also negatively effect the efficacy of TMS interventions.

We are sending people to the moon for the first time since 1972 TODAY. Don’t let this historic moment pass you by!
As we enter a new month, I'm leaving thermodynamic computing and going back to quantum computing. The fact that thermo systems will reach 100M+ pbits in scale within a year is too overwhelming to think about, I miss the coziness of...
I don't wanna say but I told you guys Touching receipts -> BPA enters your bloodstream High BPA levels in adolescents -> 50% reduction in Testosterone levels

Immunosenescence and Allergy: Molecular and Cellular Links Between Inflammaging, Neuro-Immune Aging, and Response to Biologic Therapies https://t.co/DMVxerI64T https://t.co/TUPGK6SqUK

Speaking at the Federation Council, Roskosmos chief also confirmed that the post-ISS station would be assembled at ISS out of (New) Node, Science & Power and Airlock modules (as I illustrated back in 2021 ;) Context: https://t.co/wVxTkUEbNa https://t.co/zOHPUfG7hC

If you're looking for a reason to get psyched about the Artemis II launch today, check this out: https://t.co/qlqzQNJzby https://t.co/hbJQThOk2Q
The flimsy case for evolving dark energy There's been a lot of talk about evolving dark energy, and how DESI data demands it. But the case for this remains somewhat weak, while the true underlying puzzles remain unsolved. https://t.co/Xh1dgGu3kI

According to Roskosmos chief, the "first firing of the methane-oxygen engine (presumably the RD-0177M demonstrator) took place just last week" (which would make it between March 23 and 29). Context: https://t.co/RwOb1eWwT3 https://t.co/lZc1VCXbeJ

This study on visceral fat loss blew my mind... It found that sustained visceral fat reduction over years was linked to preserved brain volume and cognitive function in middle age. They tracked people for up to 16 years, and those who lost...
People are going to the Moon (well, almost) again tonight. Saying it five times in a row, and each time feels a little better.

Another feature adding to my terminal plasmid editor is a transcriptome browser. Helps you quickly build blast databases from a heap of transcripts in a single fasta file. Gonna add HMM/Pfam detection and Pfam search. I really love this current...
In addition to the livestream, NASA is also posting live Artemis II updates here: https://t.co/9gcpALfGtC
Science is transcendent -- true to nature in another galaxy on other side of the observable Universe. Humanity could use some of that transcendence here on Earth...by leaving Earth to go to the Moon. "58 Years After ‘Earthrise,’ NASA’s New...

Astaxanthin is a major antioxidant that's 100x more potent than vitamin E and vitamin C - protects skin against UV damage - lowers inflammation and neuroinflammation - lowers lipids and blood pressure - protects against oxidation of fats - protects the eyes - senolytic properties - lowers...
I wrote today about a big study on replication--and why it's so hard to know if a study will hold up or not. Gift link: https://nyti.ms/4sNu3MF
One reason I dislike saying healthspan or lifespan & prefer aging as label for the field over longevity. Aging puts focus on its terrible consequences/pathology. It makes the field defensive like medicine not greedy as some see wanting more life...
Excited to see that the Artemis II fueling is going so well, but can't but feel ... https://t.co/gJGnTj2Cc7
I'm genuinely excited to see America headed back to the Moon. But Artemis is a moondoggle and shows we haven't learned the deepest lessons of the Apollo era. Remember that Apollo did *not* result in durable progress in space. It marked...
How Slow Waves During Sleep Take Over to Clear Metabolic Trash - https://t.co/JnnaGFUeMo via @neurosciencenew #sleep #MedTwitter #CardioTwitter #BrainHealth #dementia #lifestylemedicine #HealthyLivingCommunity #HealthyLifestyle #pavingwellness #health #mentalhealth
Direct Link Between Stress and Addiction Found - https://t.co/rwLwvh4egR via @neurosciencenew #Addiction #mentalhealth #alcohol #substanceusedisorder #health #lifestylemedicine #pavingwellness #HealthyLivingCommunity #WellnessJourney
Imagine the sheer courage of today's Artemis astronauts: testing aspects of the Orion capsule, a new and more distant orbit around the moon, a heat shield that previously disappointed, and...worst of all...an as yet untested. . . um. . ....
The first woman in history is flying to the Moon today. 💅🏼🚀💕 The launch window opens at 6:24 pm EST. Watch live on nasa.gov
Not to throw my adorable and clever students under the bus, but I asked a group of over 30 college students how many countries have put a human on the Moon. Not one student knew for sure, but most suspected...
Research on professional rugby players found that watching what they did wrong after a game led to elevated cortisol and worse performance the next game. Watching what they did well had the opposite effect, a bump in testosterone and better...
If I told you the answer to “How many ER binding sites are in MCF7 cells?” is anywhere between 1,000 and 20,000—would you believe me?
Fueling has started at Kennedy Space Center. Here’s a rundown of all the big events for Artemis II launch day. https://t.co/avBdoxvMmi
As a medical school professor, I've seen textbooks call it "metabolically healthy obesity." A new study proves that label is dangerously misleading. Karolinska Institute tracked 7,275 children with obesity until age 30. The results in JAMA Pediatrics are staggering: -> 9% of "metabolically...
Quantum computers need vastly fewer resources than thought to break vital encryption - Ars Technica https://t.co/pLuvHMFLOP
As a medical school professor, I've recommended metformin to countless patients. But a new double-blind trial just revealed something alarming. Metformin BLUNTED the insulin-sensitizing benefits of exercise in adults at risk for metabolic syndrome. The findings from a 16-week RCT: -> Exercise +...

It’s a beautiful morning in Florida. We will be watching closely as they fuel up the space launch system. The Artemis two mission will carry four people to the moon. It’s a moment in history and I’ll keep you posted.#milesobrien...

Breakthrough News: Over the past 12 months we were working in secret on a clandestine project - the foundation model for search for and communication with Extracellular Life. Today, we managed to establish our first contact. The aliens want to engage...
NASA says it is go to begin tanking the SLS for today's Artemis 2 launch attempt. https://t.co/wfaqCkBpTO
Europe faces weeks of volatile spring weather, with competing atmospheric factors raising the risk of cold spells, storms and late-season snow. https://t.co/FlIR2N8BkT

1/🚨@CaribouBio announced that the U.S. FDA has granted Regenerative Medicine Advanced Therapy (RMAT) designation to CB-011 - $CRBU allogeneic anti-BCMA CAR-T Cell Therapy for treating relapsed or refractory multiple myeloma (r/r MM) cancer which is being evaluated in the CaMMouflage...

New group preprint: "Faster Molecular Dynamics with Neural Network Potentials via Distilled Multiple Time-Stepping and Non-Conservative Forces”, which introduces the DMTS-NC approach - a strategy designed to further accelerate atomistic molecular dynamics simulations using foundation neural network models. https://t.co/SIbycvoca7 Significant Speedups: using...
You will soon be able to order sunlight the way you order a ride. That is not a metaphor. Reflect Orbital is building small satellites with deployable mirrors that can redirect sunlight to a specific area on Earth, on demand. What stands...

Building on data in untrained subjects, this study in trained athletes found that speed is not lost during detraining and may even increase. In this way, it contrasts with strength, which is lost. https://t.co/4fiSlHL1UJ

Neuroinflammation in Alzheimer's Disease: The Role of Obesity, Gut Microbiota, and Therapeutic Potential of Omega-3 Fatty Acids and Neural Stem Cells https://t.co/IB7nxSSupQ https://t.co/YSLYmsInF2

Alright, the Artemis II launch is less than a day away. So I want to address some recurring criticisms I've seen: it's too expensive, we need to solve problems down here, it's too dangerous, it does nothing for the greater...
Between 1968 and 1972, twenty-four humans entered lunar space, where the Moon's gravity dominates that of the Earth (within about 66000 km from the selenocenter). Only five of them are still alive.

Adiponectin and aging: Mechanistic insights, clinical paradox, and therapeutic horizons "Adiponectin has been implicated in aging and the onset of age-related disease.... Adiponectin signaling protects multiple tissues from age-associated decline... Adiponectin signaling agonists as therapeutics in metabolic and age-related disease." https://t.co/9NcjtjlbjR
What’s more dangerous than doing power work? Not doing it. A 2025 study of 3,889 people found those with the lowest muscle power had a nearly 6x higher risk of death than the highest group. Slow training builds slow people. Slow people die...
This tweet and accompanying paper are fairly misleading (note: paper is from July ‘24) There are many issues w the study itself that it’s a bit tough to go into here. But most importantly, the paper concludes: “Our findings support the...

Implantable islet cells could control diabetes without insulin injections by Anne Trafton @MIT Learn more: https://t.co/aPCxukXMW1 #MedTech #HealthTech #Tech #TechForGood https://t.co/hXbxvs5HTM
I am so unbelievably excited for this Artemis launch but I really REALLY wish they weren’t doing it on April fools day… the conspiracies have already started
Wishing @NASAAdmin and the entire @NASA team the best for tomorrow's Artemis launch attempt - and a special 'bon voyage' to @centerforastro alum @Astro_Christina !

This is not good. “Everywhere chemicals” leaching from plastics may have contributed to 1.97 million preterm births and 74,000 newborn deaths worldwide in one year (2018), with an estimated 6.69 million years of life lost. Born at 28 weeks. The...
I think it will actually launch this time for the simple reason that NASA events and holidays (however small) just like to go together.
The scientific consensus is that surface warming is linear in cumulative carbon emissions--there is no evidence of any "tipping point" behavior in global surface temperature (though some climate subsystems e.g. ice sheets may exhibit threshold behavior): https://t.co/9SZ2bigjAM