
Therapeutic Phlebotomy Restores Bone Marrow, Reverses Aging
Periodic Therapeutic Phlebotomy Mitigates Systemic Aging Phenotypes by Promoting Bone Marrow Function “our work provides preliminary evidence suggesting that periodic therapeutic phlebotomy exerts anti-aging effects by restoring bone marrow function and mitigating aging phenotypes, subsequently driving peripheral blood functional restoration.” 👉 “ Here, we demonstrate that periodic therapeutic phlebotomy in D-galactose-induced aging models exerts significant and comprehensive anti-aging effects, which is reflected by a notable improvement in aging-associated behavioral deficits and neurogenesis, a significant decrease in the level of circulating senescence-associated secretory phenotypes, and an obvious mitigation of aging-associated structural degradation and molecular alterations within the muscle, bone, liver, kidney, and nervous systems. 👉 Mechanistically, periodic therapeutic phlebotomy induces bone marrow microenvironment restoration through functional rescue of mesenchymal stem cells and endothelial cells, thereby reestablishing balanced hematopoietic homeostasis. This hematopoietic revitalization subsequently drives systemic improvements in peripheral blood composition and function.” https://t.co/4OZNk572pr
Jobs and I Recognized Siri’s AI Breakthrough First
The Siri team says only two people got it. Me and Jobs. The full story behind Siri for those who care: https://t.co/P0uMBXpb9J (it was launched in my house, and something worth bragging about. It was the first consumer app to...
AI Momentum Shifts to Revenue, Anthropic Outpaces OpenAI
The race in AI is starting to shift toward real business adoption. Anthropic is rapidly gaining traction with paying customers, driven by strong demand for its Claude Code tools, while growth at OpenAI appears to be leveling off. The signal is clear....
Saving Money by Cutting Core Software Wastes Resources
Alex Rubalcava on the SaaS-pocalypse: "I think that it's going to be a really poor use of money and scarce resources like developer time for a company to try to save a few hundred thousand bucks to rip out...
Small-Scale Renewables Power Real, Resilient Progress
Small-scale energy solutions deserve more attention. A 1kW wind turbine may not sound dramatic, but that is often how real progress looks: reliable, practical, and deployable where it is actually needed. Not every clean energy breakthrough has to be massive. Sometimes the value...
Nature-Inspired Porcospino Flex Tackles Inaccessible Terrain
From Nature to #Robotics: Porcospino Flex Navigates the Unreachable by @rohanpaul_ai #Robots #Engineering #EmergingTech #Innovation https://t.co/uFStvXr4Nw
Muse Spark Surpasses Expectations After Llama 4 Hiatus
I think Muse Spark came in far better than most were expecting as the first new model attempt from Meta, especially given the fact that it has been a year since Llama 4 with no models at all (and that...
AI Glasses Bring Remy: Memory Assistant Everywhere
Wait until you have this on your AI glasses. This is part of the Holodeck I keep talking about. This thought written on a Silicon Valley freeway in my autonomous car.
Policy-Driven Scaling Made Renewables Finally Cost‑competitive
Solar, wind, batteries*, and EVs only dropped in price to where they win economically because earlier policy driven by environmental concerns scaled them. * - Batteries are a partial exception due to early scaling from consumer electronics. But that only...
Atlas Robot Advances From Walking to Heavy Lifting
From Walking to Heavy Lifting: Atlas Shows Off Next-Level Skills by @lukas_m_ziegler #Robotics #ArtificialIntelligence #Innovation #MI #ML #Tech https://t.co/ZZiil46lwU
Claude's Performance Decline Drives Users to OpenAI
I understand there’s a ton of Claude fans out there. I was there too 4-5 weeks ago. Then it got way way way worse and without explanation. What’s worse is that I would consider myself a heavy power user. What about...
Prioritize First-Class Agent Memory Systems, Not Storage
Thinking about https://t.co/hdRfMQoQNm, Garry’s post made me realize we’re heading in the right direction, but we need to make agent memory systems first class in journey and make kits continuously improve. I don’t think we should store memories though, only...

Platforms Profit From Both Attention Hijacking and Recovery
Platforms charge companies to hijack our attention, then charge us to reclaim it. A very elegant way to monetize both the problem and the fake solution. YouTube perfected the art of monetizing both the interruption and the escape. #AI #Advertising #AttentionEconomy...

AI Token Demand Set to Explode, Driving Datacenter Surge
This chart puts the datacenter demands into perspective very clearly. Amazon has done more capex in the last 3 years than its entire history. Right now most AI adoption is on chat tools that are relatively token efficient. Comparatively, coding...
Heat Shield Fine Despite White Discoloration, Says Jared
Jared clarifies the status of the heat shield; some observers were concerned by an area of white discoloration but it's no big deal.
SpaceX Valued Near $15 B, Not $16 B, with Starlink $11‑12 B.
The legacy Twitter business was supposed to be $2.9B last year and xAI was hoping for $500M. That would mean SpaceX itself is just over $15B (not the $16B many have been stating) and Starlink is in the region of...

Separate Negative Runs, Group Positives for Cleaner Circuit
Realized late this afternoon that I had messed up on the Enterprise. In an effort to reduce wiring and tidy things up and I had grouped the negative runs. The MOSFET switches that I’m using switch on the circuit via...

AI Lets Sales Scale Without Adding Headcount
Scaling Without the Headcount: How AI is Redefining Sales Efficiency by @Timothy_Hughes https://t.co/DxLm3lfJ1t @DLAIgnite #SocialSelling #DigitalSelling #Sales #SalesTips #SalesLeader #Salesforce #SalesEnablement #Marketing #Leadership #ArtificialIntelligence #TechNews https://t.co/ZvpjkYB4fK
Droptec Launches Advanced Net Gun for Drone Defense
#Drone Defense Reinvented: Droptec GmbH Introduces Advanced Net Gun System by @IntEngineering #Innovation #EmergingTech #Technology #Tech https://t.co/Mg3WtW8EV1
AI Video Leaps From Slides to Cinematic Shots
Six months ago, AI video looked like a PowerPoint with motion blur. Today, Seedance 2.0 generates physics, audio, and cinematic shots from one image. And GlobalGPT is providing Seedance 2.0 with no limits, no restrictions and no invite codes: https://t.co/Qzg0FX3EcS
Zero‑G Liquid Storage Set to Revolutionize Space Missions
New Zero-G Liquid Storage System Could Transform Space Missions by @interesting_aIl #SpaceTech #Tech #Technology #EmergingTech #Space https://t.co/RrdFcR9tCT

Safe Cell Reprogramming Restores Identity, Nature Reports
You're confused. Let me explain: My student @Y_Ryan_Lu worked for years to find a SAFE way to reprogram cells so they'd only RE-GAIN identity, not LOSE it, as Prof Yamanaka showed We tried innumerable combos to find the solution Story is @Nature...
Vendors Prioritize Subscription Revenue Over Customer Value
Vendors profit from annual subscriptions before you see business value. This system prioritizes their financial gain over customer needs. Next, we’ll explore consultant motives and the full machine benefiting these parties. #BusinessStrategy #CustomerValue #VendorAgreements https://t.co/lF4yYKZPaA
XPeng’s IRON Robot Shows Humanoids Ready for Everyday Use
XPeng’s IRON #Robot Proves Humanoids Are Ready for Daily Tasks by @TheHumanoidHub #Robotics #ArtificialIntelligence #Innovation #Technology https://t.co/WCkK9GCHkG

Amazon Leo to Deploy Ka‑Band mmWave by 2026
Amazon Leo plans to launch services commercially by mid-2026 according to Andy Jassy. The spectrum for user links is millimeter wave (Ka band). Shannon-Hartley Theorem: C = B \log_2(1 + S/N) Where: •C = channel capacity (bits per second) •B = bandwidth (Hz) •S/N =...

Humanoid Robot Alex Gains Real-World Skills Pre-Debut
US: Humanoid #Robot Alex evolves with real-world capabilities ahead of public debut by Jijo Malayil @IntEngineering Learn more: https://t.co/8g7D9LB1R4 #Robotics #EmergingTech #Technology #Innovation https://t.co/R8mRWjvXdq
Artemis 2: A Bright Gift Amid Growing Negativity
what a gift to humanity drowning in so much negativity lately - Artemis 2 was... We should celebrate our astronauts, engineers, scientists, and all the awesome people at NASA who made it possible.
AI Set to Supercharge CAD Engineering by 100×
More of this please Actually if you believe computer aided design and engineering is about to become 100x more awesome thanks to AI, it might just happen now
Boston Dynamics' Arms Achieve 24 Degrees of Freedom
24 Degrees of Freedom: Inside Boston Dynamics’ Powerful #Robotic Arms by @fluxfolio_ #ArtificialIntelligence #Innovation #Technology #Engineering https://t.co/wEKK0FSO64
Button Color Drives Massive CTA Performance Boost
Legit - changed the color of a button. We did some analysis and testing on ads of color theory and how their audience responded. We found drastic changes based on color of CTA. So we applied that to the website.

Three Key Pillars That Define Successful AI Strategies
Three Pillars That Make Or Break An #AI Strategy by Monisha Somji @Forbes Learn more: https://t.co/8jUOLyD3c5 #ArtificialIntelligence #MachineLearning #ML https://t.co/TKLDqGSdyX
AI Offers Insight; Humans Retain Final Judgment
A fun use of AI: upload a giant wine list and ask for the most unique bottle under your price point based on your palate. A serious use of AI: the exact same idea — in high-stakes work. AI gives you access...
First FDA‑cleared Humanoid Robot Performs Precise Spine Surgery
World’s First Surgical Humanoid #Robot Achieves FDA-Cleared Precision in Spine Surgery by @StarSnap_1 #MedTech #Healthcare #HealthTech #Tech #TechForGood https://t.co/4HLmX8wb7y

High‑dose Dexamethasone Improves Outcomes in Newly Diagnosed Myeloma
Lenalidomide + high-dose dexamethasone (RD) vs lenalidomide + low-dose dexamethasone (Rd) as initial therapy for newly diagnosed multiple myeloma: an open-label RCT [10/22/2009] @VincentRK et al. @TheLancetOncol https://t.co/hXxlFINejC #NCT00098475 #EAonc E4A03 #mmsm #caxtx #ctsm https://t.co/GnehXu71Td

Grateful for the DIY Arduino ESP32 Watch
@olleewatch , I love this dearly; thank you for making it. #tech #arduino #esp32 #watches #electronics

AI Advice Still Needs Doctor Confirmation for New Parents
A month into fatherhood, I've used every clinical AI tool I have access to: OpenEvidence, DoximityGPT, Gemini - and I'm STILL asking my doctor friends for advice... but WHY? Isn't AI supposed to make physicians obsolete? Let’s not act surprised: of...

Earth: A Fragile Lifeboat, We’re All Crew
Christina Koch’s reflection on Artemis II crew: “When we saw tiny Earth…what struck me wasn’t necessarily just Earth. It was all the blackness around it. Earth was just this lifeboat hanging undisturbingly in the universe…Planet Earth. You are a crew.” https://t.co/ck2ZZjj1ZC

Plaud NotePin: AI Wearable Boosts Meeting Note‑Taking
I review the Plaud NotePin Wearable AI Note Taker device and find that there's a lot to like with this smart little gizmo. It's particularly helpful for meetings and lectures, as I demonstrate in this detailed video: https://t.co/Q45YtD8M9E #ai #aiWearable...
Cheap Scanner Lacks USB Port, Buyer Regrets Purchase
So glad the $500 printer / scanner combo I bought last year doesn't have a flashdrive port. So, so happy. /s (never, ever buying a scanner like this again. 🤬)
Human Commands Dozens of Robots: Control's Future
One Human, Dozens of #Robots: The Future of Control Is Here by @CyberRobooo #Robotics #Engineering #ArtificialIntelligence #Innovation #Technology https://t.co/5wACrsFngs
Audiophile-Grade Sound, Budget Price, Plain Design
Audiophile level headphones for much less than you expect? I check out the Dekoni x HiFiMAN Cobalt Closed-Back Headphones and find lots to like. Well, other than the humdrum styling, that is: https://t.co/J7kBkKHwQo #audio #audiophile #headphones @dekoniaudio @hifimanofficial

NMN Reverses Ovarian Aging in Mice, Human Trials Needed
DATA REPRODUCED: In old female mice, NMN restores ovarian follicle reserve in 10 days. Optimal dose was 200-500 mg/kg body weight/day. Equivalent to 35-45 in woman years. Clinical trials are needed 🐭🧓 https://t.co/oVeGUZSaQ0
Anthropic Holds Back Its Most Powerful AI
Why Anthropic Refused to Release Its Most Powerful AI Yet? https://t.co/1RIVXmUYqh via @YouTube #mythos #anthropic #GenerativeAI #AI #artificialintelligence #GenAI #LLMs @PawlowskiMario @chidambara09 @Ym78200 @CurieuxExplorer @efipm @bigfundu @sayedflah @Ronald_vanLoon @cyngn @belindabeibi @odisseiaalfa @DigitalColmer @MyCompanionsAI @KirkDBorne @patricegorissen @jeffkagan @EdwardKens50830 @enilev @insom_ai333 @ChrisCCrowley...
NVIDIA GTC 2026 Unveils Next‑Gen Humanoid Robotics
Robotics at NVIDIA GTC 2026 https://t.co/M0J97VUKjA via @YouTube #gtc #humanoidtech #humanoid #robot #Robotics #AI #TechRevolution #TechInnovation #ArtificialInteligence #PhysicalAI @lexfridman @KirkDBorne @Ronald_vanLoon @erikbryn @antgrasso @sallyeaves @Nicochan33 @HaroldSinnott @mvollmer1 @marcusborba @CatherineAdenle @vinod1975 @YuHelenYu @ingliguori @fogoros @ylecun @TerenceLeungSF @SourabhSKatoch @wil_bielert @HsrYueli @faustospain @Whats_AI...
Hexapod Robot Adapts Terrain with Switchable Locomotion Modes
Multimodal Hexapod #Robot Switches Locomotion Modes to Adapt to Any Terrain via @ZappyZappy7 #Robotics #EmergingTech #Technology #Innovation #TechForGood https://t.co/DEVyTek5is
Chinese Firm Unveils Advanced Robotic Hand
New robotic hand by Chinese tech company https://t.co/KwdmBOyRTl via @YouTube #humanoidtech #humanoid #robot #Robotics #AI #TechRevolution #TechInnovation #ArtificialInteligence #PhysicalAI #robothand @AlbertoEMachado @Eli_Krumova @postoff25 @Khulood_Almani @anand_narang @NutritiousMind @baski_LA @TanyaSinha_ @devaang @AlAmadi1 @jeancayeux @enilev @efipm @mvollmer1 @Nicochan33 @RagusoSergio @FrRonconi @Shi4Tech @sallyeaves @LaurentAlaus @Fabriziobustama @smaksked...

Saramonic Air SE Delivers Reliable Audio Over Football‑Field Distances
Saramonic Air SE wireless microphone review, including tests and audio demo. This compact wireless lav mic system keeps a strong connection at distances beyond the length of a football field, giving vloggers tons of flexibility. My review: https://t.co/9xHsO8Y3WI #microphone https://t.co/hCCYfj6fPF

Passive AI Strategies Undermine Sales Revenue Goals
Rethinking the Sales Process: Why “Wait and See” AI is Failing Your Revenue Goals by @Timothy_Hughes https://t.co/7UsnSpKjGN @DLAIgnite #SocialSelling #DigitalSelling #Sales #SalesTips #SalesLeader #Salesforce #SalesEnablement #Marketing #Leadership #MarketingStrategy #ArtificialIntelligence
gpt-5.4-mini Cuts Cost, Boosts Speed and Accuracy
Used #gepa #optimize_anything to replace sonnet calls with gpt-5.4-mini calls for transcript entity extraction. Needed 2 passes on full pod transcripts but gpt-5.4-mini still cheaper / faster by ~2x / 5x and yielded better results.
Write Daily, Publish Publicly, Turn Content Into Sellable Capital
My free guide to building a massive online audience: Write: • 300 words per day • Create with your reader Publish: • Practice in public • Double down on what works Expand: • Turn high-performing topics into longer-form pieces • Turn longer-form pieces into Intellectual Capital you can sell