
Your CFO wants more efficiency. Your CMO wants more volume. They're both right. And both wrong. The real question isn't "what should our target be?" It's "where are we at on our marginal frontier?" Spending power = the amount you can increase spend before CAC rises $1. Most brands are either: • 30% under their frontier (leaving money on the table) • 20% over it (burning cash for vanity revenue) The Bridge: contribution margin optimization isn't about spending less OR more. It's about spending exactly at the point where the next dollar nets you zero. Then deciding how far past zero your P&L can afford to go.
These 3 changes to our cold email copy 5x’d demos booked last week. OLD VERSION: Subj: $18 per lead is a lot Body: You’re paying ~$18 per lead or more on Meta right now. And, some more if they don’t convert for the first...

Trust is built over time, and broken in an instant. Is your "scalable" AI strategy mortgaging trust for visibility? I have had to accept my brand getting "less visibility" in GEO to maintain a standard, because we have just that ......
I let Duke Energy control my thermostat. I don’t regret it. #energysky -- via Canary Media: https://t.co/LfzMpD9SLF

The SLS Core Stage is 100% full with liquid hydrogen, reaching that step without the leaks experienced in the first Wet Dress Rehearsal. Core stage LOX also full. Upper stage in progress. https://t.co/l57ViNyv7v https://t.co/osaGFUDs2r
🆕@Nature Genome sequencing of >800,000 people finds Epstein-Barr virus reads and their association with other autoimmune diseases besides multiple sclerosis, including type 1 diabetes, inflammatory bowel disease, and hypothyroidism https://t.co/FKCV4OInT5
Humanoid robotics has split into two timelines: China → deploys, iterates, scales Others → demo, debate, delay The advantage isn’t better robots. It’s tighter AI + manufacturing + deployment loops. Real-world reps beat stage demos.
The 2 long-term investments I'd be making if I sell services to ensure I build something sturdy, especially given the current moment: 1. Building a business that isn't reliant on social media (or even SEO/AEO) for lead-gen. Yes, some business models depend...
No amount of technology or marketing will make a bank relevant without a challenger mindset. Culture determines whether innovation ever reaches the customer. We discuss this with @EFulwiler, CEO of Rival. Watch the full episode: https://t.co/Y31f7tnfQ6 https://t.co/hmRJoRouya

"Solar and batteries can power the world" Tom Brown is mostly on BlueSky these days but this is a great blogpost so I'm sharing it here too. https://t.co/KU6aqsHfEZ https://t.co/1pVWCGUOKs

We often hear the claim that intermittent solar and wind are cost-competitive with reliable sources of electricity. This is an accounting fraud. The cost of solar and wind is paid on top of the cost of an on-demand power source, not instead...
Two massive neobank acquisitions just happened. Stash sold to Grab for $425M (below its $747M raised) and Step got acquired by MrBeast. The neobank middle class is getting repriced: if you can't hit escape velocity, you become infrastructure for someone else's...

Dr. Tour is excited to be speaking at the upcoming Graphene-Connect 2026 happening on March 11–12! @Graphene-Connect @metalgrass #graphene #science https://t.co/q3tYr2c4oI
Not a preplanned motion sequence. A robot deciding mid-jump what to do next. [📍 paper + demo] Researchers just showed a humanoid doing real parkour using only onboard perception. No motion script, no fixed obstacle layout. The system is called Perceptive Humanoid Parkour (PHP). Instead...
🎙️ Evan Beard is the co-founder and CEO of Standard Bots , building AI-trained industrial robot arms designed to automate real factory work, not demos: In this episode, Evan shares a founder path that started in software startups and Y Combinator...
I know founders with perfect Shopify themes getting 1% conversion. I know founders with basic themes getting 6% conversion. Theme beauty doesn't matter. Offer clarity does. Fix your messaging before your design.

lol Grokipedia doesn’t even show up on the @sistrix visibility comparison chart I had to check multiple times to make sure I didn’t type the domain name incorrectly 🤣 https://t.co/NMUTsbS7Yr
Who should we be working with for international 3PLs? Looking to expand to Canada, Australia, UK to start.

Accenture combats AI refuseniks by linking promotions to log-ins https://t.co/ZmTs7FvM9v #ArtificialIntelligence #Innovation #Technology #Tech #TechNews https://t.co/jGIaUWQx0f
Altesa, run by former Trump official, raises $75M for well-traveled lung drug https://t.co/bUx5dcvNJy by @gwendolynawu #biotech #startups

Went deeeeepp on the memory industry in this report. No one used to want to cover memory, and now it is all the industry/supply chain wants to talk about. Some juicy stats 😀 https://t.co/QSHAd1OxK2 https://t.co/dbC4xNxVte
These proposed reforms to pre-clinical drug development and to smoothing the transition to first-in-human studies could be the most consequential steps toward leveling the playing field with China. https://t.co/oVY6N3xo9Y

Is $NOW really at risk of AI disruption? $NOW is down ~52% from ATH. The bear case is simple: ~97% of revenue is seat-based. If AI reduces headcount, seat growth slows. But the real question is whether AI replaces ServiceNow… or makes...
The most used multicancer early detection (MCED) blood test (liquid biopsy) uses methylation (GRAIL). But combining that with DNA fragmentomics, as reported today @NatureCancer, improves early detection https://t.co/VkNDR4XuW3
ElevenLabs just lost its moat 🤯 Voicebox just dropped: → Powered by Alibaba's Qwen3-TTS for near-perfect cloning → Ships with a DAW-like "Stories Editor" → No cloud, runs locally on your machine 100% Open Source. 100% Local. Link to repo in 🧵↓ https://t.co/m7aQ5wutK3
#Noire #AI #Avatar #Robotics #Engineering #Professor teaches Robotics as part of her STEM for the streets. Changing the face of STEM one robot at a time. Support her books, robots, apparel and more at NoireSTEMinist.com
Claude Code launched just one year ago. Today it writes 4% of all GitHub commits, and DAU 2x'd last month alone. In my conversation with @bcherny, creator and head of Claude Code, we dig into: 🔸 Why he considers coding "largely solved" 🔸...
Distribution and the human attention premium That marketing and distribution become the principal challenges of scaling content in an attention landscape awash in it seems like an obvious outcome as production costs collapse. But it has not yet emerged as a...
You’re deluding yourself into thinking you’re organized by staring at a dashboard with 50 metrics... … and somehow, you're completely missing the only 4 that actually matter: MER (Marketing Efficiency Ratio): This is your early-warning alarm. If MER dips 10-15% below target, something's leaking....
FDA leaders say one pivotal trial, not two, should be ‘default’ for drug approvals https://t.co/ADRb1miphf by Kristin Jensen #biotech
This is an interesting thread. Everyone is suggesting tools to solve the problem. I’d start by asking more about the data and the questions the customer is trying to answer or problems they are trying to solve first before recommending...
He refused to sell his product until his team used it themselves first. Then 100 customers signed in 6 weeks. 1,000 in year one. @markowitzadam built @DrataHQ to $100M+ ARR by proving trust with evidence - not promises. https://t.co/MZNP2TLl8H
Your first Terraform project will be ugly. Your second one will still be ugly. By the tenth, you’ll understand why the first nine failed. Progress in tech is cumulative. 💗
Sufficiently advanced agentic coding is essentially machine learning: the engineer sets up the optimization goal as well as some constraints on the search space (the spec and its tests), then an optimization process (coding agents) iterates until the goal is...
As the semiconductor industry gets serious about monolithic 3D integration, indium-based oxide semiconductors are drawing more and more attention. https://t.co/TCRHH3C2p6 #semiconductor #3Dintegration @ieee_iedm #indiumoxide #BTI #IGZO

Impactful discussion with 🇳🇱 @MinisterKGG, 🇬🇧 @Ed_Miliband, 🇦🇺 Stephen Jones, 🇪🇸 Sara Aagesen Muñoz & other leading figures on what is needed to ensure electricity systems can cope with the growing range of threats they are facing, both old and...
Silicon Valley’s energy appetite is so insatiable that it is now trying to build a colossal shadow power grid for itself nationwide. But will it work? Said @JigarShahDC : “This whole thing feels like a fairy tale concocted on...
What happens when you drop great tech into a fee-for-service system? Farzad Mostashari has a blunt answer—and it’s worth hearing. See what Aledade is doing to make the math work for value-based care: https://t.co/iMKzsdQSrl @AledadeACO #ValueBasedCare #HITsm https://t.co/lL49Ha2UHC
AI chip startup Taalas @taalas_inc is showing off a chip that can do 16,000 tps/user on Llama3.1-8B, many multiples of its nearest competitor. The catch? The chip ONLY runs Llama3.1-8B, and a model like DeepSeekR1-671B would need 30 separate tapeouts: https://t.co/IJuprQZqaE

Recently I found a YouTube channel — TrainWithShubham He has explained Linux for DevOps in Hindi in a very clear and practical way. From basics like: • What is Linux • Commands • Users & permissions • Networking • LVM Everything is covered in one structured session. If you’re...

Important discussions with 🇳🇱 @MinisterKGG, 🇺🇦 @Denys_Shmyhal, 🇱🇹 Žygimantas Vaičiūnas, 🇵🇱 @motykamilosz & others on Ukraine’s energy security Ukraine’s energy system is facing major challenges, but steps can be taken now to meet urgent power needs while preparing for the future...
SMART Health IT team submitted formal comments on HTI-5. Feel free to read and borrow language. Briefly: Deregulation should not mean losing sight of whether interoperability is actually working. (HTI-5 risks eliminating the instrumentation ASTP/ONC needs to steer a successful...
No because I talk directly with my sites Each of my sites (almost, I'm still migrating) is now on their own Hetzner VPS Like https://t.co/2R4tRNJF0z for example, on that VPS I have Claude Code and https://t.co/wNWBUhh9QZ I asked Claude Code to install that...
Omarchy comes with strong lineup of default themes, but the community has been adding a million more on top of that. Love to see it.
This is a quick question with an equally quick answer—nothing.It’s just like what happened to the movie industry when the camcorder came out. Why? It’s not the camera, it’s where you point it. Traditional software companies do not maintain their competitive...
2026 is the year you launch your first ecom brand. Here's 100 niches you could innovate on today: 1. Wearable blankets (Don't copy me haha) 2. Weighted products (blankets, eye masks, lap pads) 3. Pet comfort products 4. Pet travel accessories 5. Ergonomic pillows 6. Sleep accessories 7....
No matter how sunny a region it is deployed in, solar is not a reliable source of power. Even in sun-drenched Arizona, a series of three low-pressure systems wiped out most of the state's solar energy for 6 days in January...

.@AirbusSpace, after annus horribilis in 2024, reports 16% increase in revenue and return to profitability in 2025. Parent @Airbus says preparations for space merger with @Thales_Alenia_S @LDO_Space continue. @defis_eu @esa @EutelsatGroup. https://t.co/hqR8FTeOcS https://t.co/R22dQJ3mJk
Most UX teams have a bottleneck problem. You've done the research. You know what users need. But every time someone across the organization has a question about users, they have to come to you. You become the gatekeeper. Not by choice. Just...

💬 Having each of your sites/apps as a chat is such a logical idea once you do it It can message you if there's an error (I had this for years already, every server, PHP or JS error or unexpected problem...