Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
The Montreal Heart Institute (MHI) has opened the Centre for Advanced Simulation in Heart Valve Therapy, the first high‑fidelity valve simulation centre in the Americas. Acquired from Simulands, the platform supports training across transcatheter, repair and emerging minimally invasive procedures. The initiative is a core pillar of MHI’s goal to double the number of valve‑disease patients it treats by 2028 and to train 40‑50 international surgeons each year. Funding from the MHI Foundation and technology partners Abbott and Simulands made the launch possible.
The CHEO Research Institute’s pediatric AI tool, ThinkRare, is moving beyond its home site to McMaster Children’s Hospital, Alberta Children’s Hospital and Stollery Children’s Hospital, marking one of Canada’s first national deployments of a real‑time, clinically embedded AI algorithm. ThinkRare...
EyePoint reported Q4 2025 results, highlighting rapid enrollment of over 900 patients in two pivotal wet AMD Phase 3 trials (Lugano and LUCHIA) with top‑line data expected mid‑2026. The company also initiated Phase 3 DME studies (COMO and CAPREIT) slated for first...
Cross Country Healthcare reported Q4 2018 revenue of $200.9 million, down 9% year‑over‑year, and a net loss of $19.7 million. CEO Kevin Clark, a co‑founder, returned to lead a turnaround, eliminating the COO role and promoting internal leaders. The company...
Sight Sciences reported fourth‑quarter 2025 revenue of $20.4 million, a 7% year‑over‑year increase, driven by $19.7 million from interventional glaucoma and $0.7 million from the newly reimbursed interventional dry‑eye segment. Gross margins remained strong at 87% overall, while operating expenses fell 25% after...
Niagen Bioscience reported Q2 2025 revenue of $31.1 million, a 37% year‑over‑year increase, and lifted full‑year revenue guidance to 22‑27%. Gross margin improved to 65% driven by a higher‑margin sales mix and inventory efficiencies. The company expanded its Niagen Plus clinic...
Ardent Health reported solid volume and revenue growth in Q3 2025, with revenue up 8.8% to $1.58 billion and adjusted EBITDA rising 46% to $143 million. However, the company lowered its full‑year adjusted EBITDA guidance to $530‑$555 million, citing accelerating professional‑fee expenses and...
Viemed Healthcare reported a 14.7% year‑over‑year revenue increase in fiscal Q2 2025, driven entirely by organic growth across its core ventilation, sleep therapy, and resupply segments. Adjusted EBITDA rose 12% to $14.3 million, while SG&A fell to 45.7% of revenue, reflecting...
Brook.ai, led by CEO Oren Nissim, is scaling its remote patient monitoring (RPM) platform to cut hospital readmissions and improve care plan adherence. The company reports over 50% of its hypertension cohort achieving control within ten weeks and a roughly...
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The viewpoint piece separates health justice from the more commonly discussed health equity, arguing that the two concepts are often mistakenly merged. It highlights how decades of research on social determinants have produced a flood of studies documenting health gradients...
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Non‑inferiority trials are increasingly employed to evaluate new therapies that may offer advantages beyond efficacy, such as safety or convenience. However, their design and analysis present unique methodological challenges that can compromise study validity. The commentary outlines essential considerations, including...
LiveRamp announced the integration of Newton Research and SemantIQ agents into its data‑collaboration platform, allowing autonomous AI to handle audience creation, cross‑media measurement and spend optimization for health and life‑science marketers. Simultaneously, Doceree launched RepTwin and the Site LLM, a...
SeeYouDoc, a Filipino health‑tech startup founded in 2018, has become a leading digital healthcare platform linking patients, clinicians, hospitals and local government units via web and mobile apps. The solution delivers telemedicine, digital prescriptions, electronic health records, appointment scheduling and...
New Zealand has rolled out an artificial‑intelligence scribe tool across every emergency department, giving more than 1,250 clinicians automated note‑taking support. The pilot showed doctors could see an extra patient per shift, and post‑deployment surveys reported 80% of staff noting productivity...
Nursing homes can boost their CMS Five‑Star ratings by adopting an "upstream" management approach that anticipates quality‑measure triggers before they occur. Operators are urged to analyze community trends, validate data, and engage interdisciplinary teams from admission through discharge. Proactive oversight...
Hill Valley Healthcare purchased two Virginia skilled‑nursing facilities from a Welltower affiliate for $82.4 million, marking the REIT’s exit from assets originally bought for under $15 million each. Capital Funding Group closed a $51.2 million bridge‑loan to acquire four multi‑state SNFs with 487...
The Therapeutic Goods Administration (TGA) has launched two concept papers for public consultation, proposing revisions to PIC/S GMP Annex 6 for medicinal gases and Annex 15 for qualification and validation processes. The Annex 6 update seeks to reflect modern manufacturing technologies and computerized...
Grow Therapy announced a $150 million Series D round, bringing its total financing to $328 million. The round, led by TCV and Goldman Sachs Alternatives, will fund expansion into employer‑sponsored mental‑health benefits, deeper health‑system partnerships, and advanced AI tools for providers and patients....
Eaton announced a suite of infrastructure‑focused cybersecurity solutions to help hospitals comply with the Healthcare Cybersecurity Act of 2025. The portfolio includes network‑managed UPS systems, a gigabit Network M3 Card with secure boot and traffic filtering, and the Brightlayer digital power‑management...
Health systems are confronting an accelerating physician unionization movement, adding pressure to labor negotiations amid a broader wave of strikes. A new “Weird Number” reveals that 20 states now require minimum income thresholds for patients receiving free or discounted services,...
CMS has issued a new toolkit to help states improve behavioral health services for children covered by Medicaid and the Children’s Health Insurance Program. The guidance highlights early screening and intervention under EPSDT, care coordination, crisis response, telehealth, and workforce...
The FBI has issued a reminder to critical‑infrastructure operators to adopt mitigations outlined in a June 2025 fact sheet targeting Iranian‑affiliated cyber actors. These actors, motivated by ongoing geopolitical tensions, frequently exploit unpatched software, default passwords, and internet‑exposed operational technology (OT)...
The Independent Medical Alliance (IMA) returned to Washington, D.C. in early February 2026 for a series of meetings with senators, congressional staff, HHS officials and national media. Representing more than 12,000 clinicians across 35 specialties, IMA presented frontline clinical data...
Following strong interest in the ASH25 hematologic malignancy intelligence report, Biotech Strategy Blog released a new strategic intelligence series covering the ASCO GU meeting data on prostate, bladder, and renal cell cancers. The first installment focuses on advanced prostate cancer,...
Physician unionization is accelerating as healthcare unions expand beyond nurses to target doctors. Membership of the intern‑resident‑fellow union more than doubled, reaching over 40,000 by 2025, and the new SEIU Doctors United group is launching a national campaign to organize...
Hospital groups and state attorneys general are urging the Centers for Medicare & Medicaid Services to withdraw two proposed rules that would ban gender‑affirming, or “sex‑rejecting,” procedures for minors and prohibit Medicaid and CHIP payments for such care. CMS estimates...
CISA issued an updated analysis of RESURGE malware on February 26, expanding the agency’s 2024 findings about the threat targeting Ivanti Connect Secure devices. The report reveals that RESURGE can persist silently on compromised VPN appliances and stay dormant until...
Nonprofit design studio Civilla released a report and toolkit to help states rapidly adapt Medicaid eligibility systems to the new work‑requirement provisions of HR 1. The resources include user‑tested online application templates, policy guidance, and recommendations such as integrating work‑related questions...
The FDA has approved the first generic version of Flovent HFA, a fluticasone propionate inhalation aerosol delivering 44 µg per actuation for asthma maintenance in patients aged four and older. The generic, produced by Glenmark Specialty SA, matches the brand’s safety and efficacy...
Lumina Care’s Chief Clinical Officer Laura Geiger explains how the company embeds telehealth into skilled‑nursing facilities to extend clinical support from admission through discharge. By establishing standardized, patient‑centered protocols and real‑time EMR integration, Lumina acts as a virtual extension of...
The telehealth urgent‑care market is hitting a wall as provider labor costs become effectively fixed by government regulation, while patient acquisition expenses continue to drain margins. Companies such as Keycare rely on health‑system referrals and Teladoc on insurer‑driven enrollment to...
A retrospective registry analysis of the 2023 Canadian wildfire smoke event found that short‑term spikes in ozone and fine particulate matter (PM₂.5) were linked to a measurable rise in both the incidence and severity of strokes in Camden, New Jersey. Ozone...
Virginia lawmakers are proposing a prescription‑drug affordability board that will use Medicare’s annually negotiated drug list as its benchmark. The board would also impose upper payment limits, creating a ceiling on what insurers pay for those medicines. This strategy would...
Glen Tullman, CEO of Transcarent, says consumer‑directed care powered by generative AI is the next structural shift in a fragmented, costly health system. His WayFinding platform moves patients from simple search to agentic actions such as automated scheduling, symptom checking,...
Cigna’s long‑time chief executive David Cordani announced his retirement, ending a 17‑year tenure and making way for COO Brian Evanko in July. His departure marks the fourth CEO exit among the nation’s top five health insurers within two years, underscoring...
The integration of AI tools such as large‑language models into clinical workflows is flattening the traditional Dunning‑Kruger curve, causing users of all expertise levels to overestimate their performance. Studies show modest performance gains but a larger perceived boost, a phenomenon...
A phase‑1 pilot of low‑dose intralesional cemiplimab in early‑stage cutaneous squamous cell carcinoma (CSCC) demonstrated rapid tumor regression with visual objective response rates of 66.7%–75% and pathologic complete responses of 58.3%–66.7%. Safety was favorable, with no grade ≥ 3 events and minimal...
The FDA has sent warning letters to 30 telehealth companies for falsely marketing compounded GLP‑1 products as equivalent to FDA‑approved drugs. The letters cite claims that obscure product sourcing and suggest the compounds are the same as regulated medications. This...
A new eye‑tracking study recorded how people with full sight, low vision, and blindness navigate a one‑mile urban route in New York City. The research found that walking speed declines with visual impairment while blind participants exhibit higher fixation rates...
Tirzepatide: In the SURMOUNT-1 trial, weight reduction percentages were dose-dependent: 5 mg: ~15.0% weight reduction. 10 mg: ~19.5% weight reduction. 15 mg: ~20.9% weight reduction (Jastreboff et al., 2022). https://www.nejm.org/doi/10.1056/NEJMoa2206038 https://www.gatlan.com/ @GatlanHealth 
The gut and environmental toxins are key underpinnings of the Parkinson's disease pandemic @jclinicalinvest https://t.co/e8o4UuIafG https://t.co/7634Yg2Qo5
Technimount has launched the Techni-INO, a crash‑tested bracket that securely holds D‑Size INOmax gas cylinders during EMS transport. The solution complies with SAE J3043 safety standards, reducing the risk of cylinders becoming projectiles in collisions or sudden stops. It incorporates...
The article challenges the notion that Direct Primary Care (DPC) can thrive solely on individual consumer subscriptions, arguing that household‑income constraints limit universal demand. It highlights Bureau of Labor Statistics data showing modest health‑care spending capacity, especially for middle‑income families...
The FDA granted accelerated approval to navepegritide (Yuviwel), a once‑weekly CNP prodrug, for children aged two years and older with achondroplasia and open growth plates. In the phase 2b ApproaCH trial, the drug raised annualized growth velocity to 5.89 cm/year, a 1.49 cm/year...
A Super Bowl ad by Novartis promotes a finger‑free PSA blood test, emphasizing a painless alternative to rectal exams. PSA screening has been shown to reduce prostate cancer deaths, yet its high sensitivity also uncovers indolent tumors that may lead...
Prime Medicine $PRME to seek approval for gene editing treatment after two-patient trial https://t.co/nBnrUzqSCN via @Jasonmmast
Interventional cardiologists performed the first ATLAS transcatheter aortic valve replacement, anchoring a Sapien 3 valve to a crushed Palmaz stent in a 75‑year‑old woman with severe non‑calcified aortic regurgitation and prior aortic dissection. The heart team selected the non‑coronary cusp for...
Cross‑sectional surveys of 225 clinicians and 522 patients reveal a stark mismatch in treatment priorities for alopecia areata. Clinicians rank rapid, near‑complete hair regrowth as the top goal, while patients place low‑risk safety profiles above speed. The data also show...
Harvard researcher Dr. Adam Rodman warns that more than one‑third of U.S. adults are already turning to large language models like ChatGPT for medical advice, despite widespread gaps in digital health literacy. Many patients struggle to download their own records...
New post‑hoc analyses of the phase 3 STOP‑HS1 and STOP‑HS2 trials show that oral povorcitinib, a selective JAK1 inhibitor, delivers rapid, high‑threshold lesion clearance in patients with severe hidradenitis suppurativa. In the 75 mg arm, up to 57% of participants achieved complete...
