Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
North York General Hospital has become the first Ontario facility to launch SmartER Zones, an AI‑driven system that reallocates patients to less crowded emergency‑department zones. Developed with Signal 1, the algorithm monitors wait times, triage data and zone capacity, then pushes real‑time recommendations to nurses via the electronic medical record. Early pilots show patients are moved up to 12 minutes faster, reducing overall wait times and the risk of patients leaving without being seen. The tool preserves clinician decision‑making while improving flow during peak demand periods.
Unity Health Toronto earned Stage 6 validation on both the HIMSS EMRAM and AMAM maturity models, marking the first time all three of its hospitals reached EMRAM Stage 6 and the first North American organization to achieve AMAM Stage 6 under the latest...
Manitoba's health ministry announced a provincewide rollout of the SAFE mobile app, extending its use from Winnipeg’s Health Sciences Centre to Brandon Regional Health Centre, St. Boniface, Victoria and upcoming sites in Thompson. The app provides emergency notifications, direct security...
Danaher announced a $9.9 billion acquisition of Masimo, a leader in pulse‑oximetry and AI‑enabled patient‑monitoring devices. The deal places Masimo as a standalone operating company within Danaher’s Diagnostics segment alongside Radiometer, Cepheid and Beckman Coulter. By adding non‑invasive sensor technology, Danaher...
Sioux Lookout Meno Ya Win Health Centre received two prefabricated modular buildings for its new MRI suite on Feb 18, after a 1,100‑km transport on a 130‑ft super‑load truck. The 1,650‑sq‑ft, magnet‑shielded facility, built off‑site by SDI Canada, is now positioned...
The Canadian Pharmacists Association (CPhA) launched the CPS Content Partner Program, offering API‑based access to its trusted Canadian drug and therapeutic database. The initiative allows EMR vendors, pharmacy management systems, clinical decision support tools, and AI‑enabled health apps to integrate...
VITALL Intelligence has launched the commercial availability of Medly®, a Health Canada‑approved digital therapeutic for heart failure developed at the University Health Network. The AI‑enhanced smartphone app, already used by more than 3,000 patients, has demonstrated a 50 % reduction in...
MiMedx Group reported record Q4 2025 results, posting $118 million in net sales—a 27% year‑over‑year increase—and adjusted EBITDA of $29 million, representing 25% of revenue. The company highlighted a strong profit profile with an adjusted gross margin of 86% and GAAP net...
Universal Health Services reported a 10% same‑facility EBITDA increase in Q2 2025, driven by higher acute‑care pricing and a 5.7% rise in net revenue. Adjusted patient days grew, especially in behavioral outpatient services, while cash flow from operations fell $167 million year‑over‑year....
Brookdale Senior Living reported full‑year 2025 adjusted EBITDA of $458 million, a 19% increase and the fourth straight year of double‑digit growth. Occupancy rose to an 82.5‑83.5% weighted average, the highest level since early 2020, while RevPAR grew 5.7% and adjusted...
Veracyte reported fourth‑quarter 2025 revenue of $140.6 million, a 19% year‑over‑year increase driven by strong testing volume and higher average selling prices. Non‑GAAP gross margin rose to 75.1%, with testing margin reaching 76.1% after the transition to the v2 transcriptome platform....
LivaNova reported Q4 2025 revenue of $361 million, a 9.5% constant‑currency increase, and delivered adjusted EPS of $0.86, marking its fifth straight year of double‑digit earnings growth. The cardiopulmonary segment grew 10% year‑over‑year, propelled by ESSENCE heart‑lung machine placements, while epilepsy...
LifeStance Health reported 2021 revenue of $668 million, a 77% year‑over‑year increase, and generated $49 million in adjusted EBITDA. The company expanded its clinician base to 4,790, a 55% rise, and now operates in 32 states with over 500 centers. Telehealth accounted...
A recent study reveals that carnitine palmitoyltransferase 1C (CPT1C) exerts dual regulatory functions in chronic stress‑induced depression‑related phenotypes. CPT1C enhances surface expression of GluA1‑containing AMPA receptors via SAC1‑mediated lipid signaling while simultaneously dampening mTORC1 activity through AMPK pathways. Genetic deletion...
Amarin reported Q4 2024 revenue of $62.3 million, down from a year earlier as U.S. VASCEPA sales fell under generic pressure. Internationally, the company added pricing and reimbursement wins in Europe and grew partnership revenue, boosting total 2024 revenue to $228.6 million....
Agilon Health reported FY 2025 revenue of $5.93 billion but posted a negative medical margin of $57 million and an adjusted EBITDA loss of $296 million, with the medical cost trend rising to 6.5% and a $35 million operating expense reduction. Management guided 2026 revenue...
Sarepta Therapeutics reported a blockbuster fourth quarter, with ELEVIDYS gene‑therapy sales of $384 million, surpassing guidance by $60 million, and total net product revenue of $1.79 billion for 2024, up 56% year‑over‑year. The company achieved GAAP profitability and cash‑flow positivity, confirming the financial...
Procept Biorobotics reported a 48% year‑over‑year revenue increase to $79.2 million in Q2 2025, driven by strong U.S. growth and a 58% surge in handpiece and consumable sales. Gross margin expanded to 65.4%, up 640 basis points, while adjusted EBITDA loss narrowed...
Pennant Group reported Q2 2025 revenue of $219.5 million, up 30.1% year‑over‑year, and adjusted EBITDA of $16.4 million, up 24.5%. All three operating segments—home health & hospice, senior living, and other services—showed double‑digit growth, with home health/hospice revenue reaching $166 million and senior...
RxSight reported Q4 2025 revenue of $32.6 million, a 19% year‑over‑year decline driven by sharply lower Light Delivery Device placements. The Light Adjustable Lens accounted for an all‑time high 86% of sales, lifting gross margin to 77.5% despite overall losses. The...
Soleno Therapeutics reported $190.4 million in net revenue for fiscal 2025, representing less than nine months of commercial sales of its VICAT XR therapy. The company turned profitable, posting $20.9 million net income and generating $48.7 million of operating cash in Q4, ending the...
Teladoc Health reported Q2 2025 revenue of $631.9 million, a modest 1.6% decline YoY, while adjusted EBITDA reached $69.3 million, hitting the high end of guidance. Integrated care drove growth, delivering $391.5 million in revenue and expanding U.S. membership to 102.4 million, surpassing 100 million members....
Sensus Healthcare reported Q4 2025 revenue of $4.9 million, a steep decline from $31 million a year earlier, as sales to its former largest customer evaporated. The company highlighted the launch of exclusive CPT codes for its SRT and IGSRT platforms, which...
![[Comment] Fundamental PEPFAR Reform Risks a Period of Structural Vulnerability in the HIV Response](/cdn-cgi/image/width=1200,quality=75,format=auto,fit=cover/https://hixhlmpcokxhartfkpyi.supabase.co/storage/v1/object/public/images/thumbnails/70f64a13fa8aff7cafa109f493d87837.webp)
One year after the 2025 policy upheaval, the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) remains without congressional reauthorization, leaving its funding and implementation in flux. The program’s shift toward an “America First” bilateral strategy has re‑engineered coordination mechanisms...
University of Queensland, backed by NIISQ funding, is developing a virtual reality programme to teach fall‑recovery skills to people with spinal cord injury. Building on seven years of research, the project aims to improve confidence, independence and long‑term outcomes by...
The American Association of Post‑Acute Care Nursing (AAPACN) unveiled a multi‑year blueprint to tackle nursing‑home workforce burnout, funding volatility, and negative public perception. Its strategy centers on culture change, leadership development, and technology‑driven documentation tools to ease staff burdens. AAPACN...
Epic announced nine significant updates in the past 30 days, ranging from new hospital go‑lives and record‑setting lab data‑exchange deployments to the rollout of its AI Charting tool. Major health systems such as UPMC and Northwell Health are deepening their...
A JAMA Network Open study of 44,078 stroke admissions found that dual‑eligible beneficiaries enrolled in Medicare Advantage (MA) were significantly more likely to leave the hospital for low‑quality skilled nursing facilities (SNFs) than their fee‑for‑service (FFS) peers. Roughly 58 % of...
Washington University researchers built a clinically informed AI system that can flag cervical spondylotic myelopathy (CSM) up to 30 months before formal diagnosis. The team trained seven models on more than 2 million electronic health‑record entries, comparing large foundation models with...
Th FDA is absolutely correct, and confirms what I’ve said all along. This $IBRX @DrPatrick “lymphopenia” push means nothing until or unless they come up with real data showing patient benefit. The “number” doesn’t matter.
A randomized trial in 16 rural communities across Kenya and Uganda paired digital tools with home‑based testing and provider training. Over two years, the intervention lowered HIV incidence from 22 to 7 cases among roughly 42,000 adults, a 70% reduction....
U.S. News & World Report unveiled its inaugural Best Home Health Agency rankings, assessing more than 12,000 Medicare‑certified providers. The analysis identified over 1,300 agencies that exceeded expectations and another 5,280 that met standard performance levels. Ratings are built on...
A new JAMA Network Open study by the Perelman School of Medicine analyzed over 160,000 visits across five University of Pennsylvania Health System hospitals and found telemedicine episodes cost an average of $96 compared with $509 for in‑person visits, a...
The South Carolina Department of Public Health announced that the measles outbreak has climbed to 979 confirmed cases, surpassing 900 for the first time in decades. The majority of infections are among unvaccinated individuals, with more than 850 cases lacking...
The American Hospital Association (AHA) praised FTC Chair Andrew Ferguson’s call to shift merger challenges from the agency’s in‑house adjudicatory process to federal Article III courts. The AHA argues that court litigation would lend greater credibility to the FTC’s antitrust...
UCLA researchers engineered T cells with two fungal proteins that let them import and metabolize cellobiose, a sugar tumors cannot use. This protected fuel restores T‑cell viability, cytokine production, and tumor‑killing capacity in glucose‑deprived environments. In mouse models of lung,...
The Congressional Budget Office now projects that the Medicare Hospital Insurance Trust Fund will remain solvent through 2040, pushing the solvency horizon 12 years farther than its 2025 estimate. The projection reflects lower-than-expected payroll‑tax collections, diminished interest earnings, and reduced...
Neuroscientist Soha Farboud demonstrated that focused ultrasound can instantly alter activity in the human frontal eye fields, biasing participants to look left or right in a computer task. The non‑invasive method delivers inaudible sound waves through the skull, reaching deep visual...
A new multicenter CHAMBER trial published in JAMA Pediatrics shows that valved holding chambers (VHCs) used for inhaled salbutamol in children aged 0‑3 produce markedly different clinical outcomes. Children treated with a higher‑delivery VHC had a 20% hospital admission rate...
The American Hospital Association (AHA) urged Congress to expand Medicare‑funded residency slots by 14,000 over the next seven years and to modify visa rules so foreign‑trained physicians can serve in underserved areas without a mandatory home‑country return. It also called...
A retrospective study of 801 multiple myeloma patients undergoing autologous stem cell transplantation found that 8.7% developed atrial fibrillation post‑procedure. Age over 65, prior paroxysmal AF, and obesity were independent risk factors, with a median onset of 13 days. Post‑transplant...
University of Houston researchers warn that implanted nerve electrode cuffs can be unintentionally activated during MRI scans. Simulations show fast‑switching gradient fields and RF‑induced heating lower activation thresholds, sometimes below peripheral nerve stimulation limits. The findings suggest existing MRI‑conditional guidelines...
The FDA has granted approval for Dupixent (dupilumab) to treat allergic fungal rhinosinusitis (AFRS) in adults and children six years and older, marking the first indication for this rare sinus disease. The approval follows a 52‑week trial that demonstrated significant...
I love that biotech has returned to the "data in the morning, raise in the afternoon" way of living its best life. $VIR $PVLA
When decisions depend on milliseconds, moving data closer to where work happens matters. Edge computing and edge AI are reshaping manufacturing, energy, healthcare, and smart infrastructure, where latency, autonomy, and reliability are critical. More: https://t.co/0MYapoejKN @TMobileBusiness Partner
Accord BioPharma’s Filkri (filgrastim‑laha) received FDA approval as the fifth biosimilar to Amgen’s Neupogen. The indication set mirrors Neupogen’s, covering chemotherapy‑induced neutropenia, AML, bone‑marrow transplant, severe chronic neutropenia, and radiation‑induced syndrome. Approval was based on two randomized trials in healthy...
New data presented at CROI 2026 show that people living with HIV who have maintained viral suppression for 25‑30 years on antiretroviral therapy regain robust HIV‑specific CD8⁺ T‑cell function. Using flow cytometry and single‑cell RNA sequencing, researchers found these cells display...
The United States faces a critical vascular surgeon shortage that is directly fueling a rise in preventable amputations. Only about 5,800 vascular surgeons practice today, while the current demand exceeds 8,000 and is projected to reach 9,000 within a decade...
The FDA has granted traditional approvals to ten oncology drugs that originally received accelerated approval after post‑marketing studies verified clinical benefit. The list includes agents such as Braftovi, Epkinly, and Padcev, with conversion dates ranging from 2022 to 2026. These...
Addus Homecare reported a 33.3% year‑over‑year rise in adjusted EBITDA to $50.3 million in Q4 2025, driven by a 25.6% jump in total service revenue to $373.1 million. Hospice services generated roughly $70 million, representing 18.8% of quarterly revenue, with daily census climbing...
