Know What's Happening in Healthcare
Know What's Happening in Healthcare
KKR and GIC delay sale of 80% stake in Philippines’ Metro Pacific Health
Private equity firm KKR and Singapore sovereign‑wealth fund GIC have postponed the sale of their combined 80% stake in Metro Pacific Health, the Philippines’ largest private hospital group. The delay is due to an inability to secure a valuation that meets investor expectations, a challenge worsened by geopolitical uncertainty from the Iran conflict. Metro Pacific Health, which retains a 20% stake, had hoped to acquire an additional share as part of the transaction.
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By the numbers: Syneron Bio raises $150M Series B
Singapore passed a Health Information Bill requiring all licensed providers to share key patient data via a national EHR, with cybersecurity safeguards and a 2027 rollout. Guyana launched a national EHR that includes online appointments and imposes hefty fines for data breaches, aiming to cut waiting times and digitise records. The UNDP is facilitating a Zambia‑India partnership to build interoperable, open‑source medicine traceability systems. Spain is consulting on a Royal Decree to make waiting‑list data transparent and analytically accessible for primary care.
Never‑smokers now account for 10‑20% of U.S. lung‑cancer cases, a share that is climbing despite overall declines. Current USPSTF guidelines limit low‑dose CT screening to heavy‑smoking adults, leaving most never‑smokers unscreened. Shira Boehler’s incidental finding on a whole‑body MRI prompted...
The FDA is actively phasing out animal‑testing requirements for certain therapies, a move echoed by the NIH and codified in the pending FDA Modernization Act. This regulatory shift opens the door for artificial intelligence and human‑derived organoid models to become...
Are people actually aging slower today? Or are we just cherry picking the data? We are in the beginning of a longevity revolution.
Treasure Health, a Florida hospice provider, has added its first chief operating officer, Shannon Cooper, and appointed Jennifer Creel as chief clinical officer to spearhead a people‑centered innovation agenda. The leadership duo will focus on compliance, workforce support, and mission‑aligned...
A large Swedish cohort study of 2.7 million children tracked over 35 years shows that while boys are diagnosed more often in childhood, the male‑to‑female autism ratio narrows to about 1.2 by age 20 and may reach parity in adulthood. The...
In this 16‑minute DDW Highlights episode, host Bruno Quinney recaps five major drug‑discovery stories from the past week, focusing on a breakthrough study linking specific biomarkers to improved cancer survival rates and the launch of a multinational consortium tackling chronic...
A ValuePenguin study finds that a median‑income American household would need to allocate about 7.3% of earnings to afford a two‑milligram monthly supply of Ozempic, the flagship GLP‑1 weight‑loss drug. In the poorest states, the cost can approach one‑tenth of...
Tanaka Precious Metal Technologies has built a total‑solution system for contract manufacturing of in‑vitro diagnostic test kits, adding dedicated dispensing and packaging lines for extraction buffer. The new infrastructure lets the company handle every step—from assay development to final product...
https://open.substack.com/pub/pauloffit/p/weaponizing-the-fda-against-vaccines?utm_campaign=post-expanded-share&utm_medium=web A closer look at the FDA's recent kill shot against an mRNA influenza vaccine.
Dr. Ronald L. Lindsay recounts how he built a fully operational pediatric medical home at a regional military hospital in just two and a half years, delivering 24/7 care to vulnerable children from worldwide military families. His interdisciplinary developmental‑behavioral clinic...
The article argues that the next breakthrough in immunology and inflammation (I&I) therapeutics will come from multi‑drug and multi‑target strategies rather than single‑target antibodies, which have hit an efficacy ceiling. It traces the evolution from early blockbuster biologics like Humira...
Dave Newman, MD, Chief Medical Officer of Virtual Care at Sanford Health, explains how the system’s expansive virtual care program—spanning 78 specialties across 300,000 square miles—has become essential for rural patients, saving them an average of 176 miles per visit....
In a healthsystemCIO webinar, senior IT leaders from RWJBarnabas Health, Ardent Health Services, and the University of Maryland Medical System discussed how to manage the flood of application requests while fostering innovation. They emphasized establishing a single, standardized intake point,...
Ocular Therapeutix announced that its experimental drug Axpaxli met the primary endpoint in a Phase 3 trial for wet age‑related macular degeneration, maintaining vision in 74% of patients at nine months and 66% at one year after a single injection....
I interviewed a dual-boarded psychiatrist and internist who warns that the ambiguity of CPT codes is being used to criminalize physicians. Dr. Muhamad Aly Rifai joined me to discuss the chilling case of Dr. Ron Elfenbein. During the COVID-19 pandemic, Dr. Elfenbein...
Researchers have engineered a tumor‑targeting, tumor‑microenvironment‑responsive supramolecular nanoprodrug that switches size to enhance deep tumor penetration. The nanoprodrug simultaneously induces redox imbalance—accumulating reactive nitrogen species and depleting glutathione—to amplify ferroptosis, while depleting cholesterol to rejuvenate exhausted T cells. This multidimensional...
Researchers have engineered β‑tricalcium phosphate (β‑TCP) granules coated with selenium‑doped mesoporous silica nanoparticles (SeMIA) linked via pH‑responsive imine–alendronate bonds. The imine linkers remain stable at physiological pH but cleave in the mildly acidic osteosarcoma microenvironment, releasing nanoparticles that selectively kill...
Airglove Medical has launched Airglove v2, an air‑warming glove designed to improve vein physiology before venepuncture. Clinical evaluations across more than 150 UK hospitals reported an 87.5% first‑time cannulation rate in oncology patients, a group known for difficult IV access. The...
Researchers have created subcellular-sized, silicon‑based microdevices that incorporate ZnO nanosheets to act as piezoelectric generators. When deformed by cellular forces or external ultrasound within the biomedical range, these nanostructures produce localized electrical potentials that depolarize cell membranes and trigger calcium...
Compass Pathways announced that its synthetic psilocybin therapy, COMP360, achieved statistically significant improvements in two identical Phase 3 trials for severe major depressive disorder. Both studies met primary endpoints, showing greater reduction in depression scores than placebo‑controlled psychotherapy. The data suggest...
I'll give a presentation today to medical students at Semmelweis Medical School about the rise of digital health and AI, as part of the 𝐷𝑖𝑠𝑟𝑢𝑝𝑡𝑖𝑣𝑒 𝑇𝑒𝑐ℎ𝑛𝑜𝑙𝑜𝑔𝑖𝑒𝑠 𝑖𝑛 𝑀𝑒𝑑𝑖𝑐𝑖𝑛𝑒 course that I co-launched. 𝐈𝐟 𝐭𝐡𝐞𝐫𝐞 𝐢𝐬 𝐨𝐧𝐞 𝐦𝐞𝐬𝐬𝐚𝐠𝐞 𝐲𝐨𝐮 𝐰𝐨𝐮𝐥𝐝 𝐫𝐞𝐚𝐥𝐥𝐲 𝐥𝐢𝐤𝐞...
Queen Victoria Hospital NHS Foundation Trust has rolled out the Archie electronic patient record (EPR) system in its Minor Injuries Unit (MIU), marking a rapid digital transformation. Within three months, the MIU recorded 16,465 annual patient visits and achieved a...
The UK Competition and Markets Authority (CMA) has opened a phase‑1 merger inquiry into Welltower Inc.’s recent acquisition of more than 600 care homes from Barchester, HC‑One, Aria Care and Danforth Care. The regulator has already served initial enforcement orders...
Seven years after Germany’s Digital Healthcare Act (DVG) introduced the world’s first reimbursement pathway for digital health apps, the DiGA ecosystem has matured from speculative beginnings to a €234 million market serving nearly one million prescriptions. The fast‑track approval process accelerated...
The Leicester, Leicestershire and Rutland ICB and Northamptonshire ICB have released a five‑year strategic commissioning plan to 2031 that places digital and data at the core of population health, neighbourhood health and prevention initiatives. A new digital and data strategy...
Artificial intelligence is moving from hype to concrete healthcare applications, as highlighted in a new AIAInow session featuring Stanford Medicine and Starkey Hearing. The event showcases AI’s role in diagnostics, where neural networks now exceed human specialists, and the transformation...
Developers of cell and gene therapies must choose between fully integrated turnkey platforms and modular, multi‑device systems. Integrated solutions deliver rapid time‑to‑value and simplified workflows, ideal for low‑volume autologous products, but they restrict reagent flexibility and scale. Modular platforms provide...
The pharmaceutical industry now invests over $5 billion annually in patient support programs (PSPs), which boost adherence by roughly 30 % and lower overall healthcare costs. Diagnostic laboratory testing is a cornerstone of these programs, delivering timely data that guides dosing, monitors...
Prior authorization is a pre‑approval step insurers require before covering a prescription or treatment. The criteria triggering a request remain opaque, turning even routine care into a paperwork marathon for physicians. Patients often endure delays, risking condition worsening while providers...
University Hospitals of Northamptonshire partnered with Isla Health to digitise and re‑engineer clinical pathways across 15 specialties, eliminating manual bottlenecks. The overhaul slashed paediatric epilepsy processing from three days to ten minutes and cut pain‑management referral times from eight days...
CStone Pharmaceuticals has secured FDA clearance for its investigational new drug application, allowing the launch of a Phase II trial of CS2009, a trispecific antibody that simultaneously targets PD‑1, VEGFA and CTLA‑4. The global study uses a parallel, multi‑cohort expansion design...
ExCellThera and its subsidiary Cordex Biologics have secured a Status 1 listing under Germany’s NUB programme for their cell therapy Zemcelpro (dorocubicel). The therapy, which received conditional marketing authorisation from the European Commission, targets adults with haematological malignancies lacking suitable donor...
China’s pharmaceutical sector is rapidly expanding, now generating its own GLP‑1 drugs alongside imported treatments. Novo Nordisk reported a 5% decline in Ozempic sales in China last year, the first dip since its 2021 launch, while sales grew elsewhere. The...
Pain that comes from mammography has been a common challenge in screening. But what if a device can change that experience? Here is a no-compression breast CT. As far as I know, no-compression dedicated breast CTs like the Koning Vera exist...
As I’ve written @BakerInstitute MAHA = a system of pseudoscience designed to undermine scientific biomedicine in America for the benefit and profits of the wellness influencer industry. It’s incredibly corrupt and endangers the health of Americans. Vaccines are just the...
Digital health firms in 2026 face a sharp tension between accelerating AI capabilities and tightening data regulations across the UK and EU. Hyper‑personalised care, driven by wearables and AI‑powered NHS apps, promises better outcomes but raises compliance challenges. New frameworks...
"Dual Wielding in I&I: A Pivotal Year Ahead" - new blog - Atlas EIR Cody Tranbarger with a tour de force on the bispecific opportunities in autoimmune... https://t.co/StQJX0vgfx
Can you guess what this device is for? It is made by Koushicare, and it helps people with dry eye. https://t.co/FilgMQ1JEy
In this episode Ryan Morrissey breaks down the essentials of Medicare for listeners approaching age 65, covering Parts A, B, C, and D, associated costs, and the critical timing of enrollment to avoid penalties. He explains the differences between original...
#GSK Exdensur (depemokimab) approved in EU for treating "severe asthma with type 2 inflammation and chronic rhinosinusitis with nasal polyps". Follows from the SWIFT and ANCHOR phase III trials.
Nema Health announced that its intensive cognitive processing therapy (ICPT) achieved a reported 99% cure rate for post‑traumatic stress disorder (PTSD) within a month, according to a new study. The findings were presented by CEO and psychiatrist Sofia Noori, who...
Danaher, a US healthcare conglomerate, is close to finalizing a roughly $10 billion acquisition of Masimo, the maker of pulse‑oximetry and other medical monitoring devices. The deal, still subject to antitrust clearance, would add Masimo’s sensor technology to Danaher’s Life Sciences...
Biopharma faces a tightening fetal bovine serum (FBS) market as U.S. cattle inventories hit record lows and European disease outbreaks curb supply. Prices have surged more than 300% over five years and release timelines have lengthened from weeks to months...
A University of Utah Health study examined red‑light photobiomodulation (PBM) as a preventive therapy for repetitive head acceleration events in collegiate football. Twenty‑six Division I athletes were randomized to active or sham transcranial and intranasal PBM over 16 weeks, receiving three...
Paras Health has appointed Balkishan Sharma as chief human resources and business transformation officer, a move that underscores the network’s drive toward operational excellence and growth. Sharma returns after a six‑year stint with the group and brings more than 18...
Radiology societies, led by the Society of Interventional Radiology, have asked Cigna to reverse policy 0539, which labels implantable peripheral nerve stimulation (PNS) for chronic pain as medically unnecessary. The groups cite robust randomized trials, FDA clearance, and a favorable...
Congress renewed the Rare Pediatric Disease Priority Review Voucher (RPD PRV) program, extending it to September 30 2029 and eliminating the dual sunset dates. The FDA released its Rare Disease Innovation Hub’s 2026 Strategic Agenda, allocating $1 million in funding and outlining plans...
Big deal scoop by @sindap and @mroliverbarnes - US healthcare manufacturer Danaher is closing in a $10bn deal to buy medical tech group Masimo. A deal could be announced as early as Tuesday provided it does not hit any last-minute...
What if a physician could inject you with a plasmid that would induce an immune response against a protein needed for cancer cell survival? This novel strategy is being tested and looks promising for refractory cancers. Talking Biotech 488 ...
