Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
The article offers candid advice for professionals targeting health‑tech startup jobs, emphasizing the trade‑off between flashy titles and actual compensation. It stresses the need for candidates to be opinionated, self‑aware of their performance level, and to leverage AI tools for productivity and outreach. Remote positions are highlighted as especially competitive, while growth‑stage startups are presented as the most rewarding environments. Specific hiring tips, from crafting targeted cold emails to asking incisive interview questions, round out the guidance.
Flashy AI tools make headlines, but industrial or medical AI often generates the real profits. https://t.co/phSUIEUOy5
A large UK observational study published in Chest found that angiotensin‑converting enzyme (ACE) inhibitor use is linked to an 18 % relative reduction in all‑cause mortality among idiopathic pulmonary fibrosis (IPF) patients, with a hazard ratio of 0.82. The analysis covered...
NIH‑backed researchers reported a four‑marker blood test that improves early detection of pancreatic ductal adenocarcinoma. The panel combines CA19‑9, THBS2, ANPEP and PIGR, achieving 91.9% overall accuracy at a 5% false‑positive rate and 87.5% sensitivity for stage I‑II disease. The study...
The episode breaks down the CMS‑9883‑P proposed rule for the 2027 ACA payment notice, highlighting transformative provisions such as State Exchange Enhanced Direct Enrollment (SBE‑EDE), the certification of non‑network Qualified Health Plans, the repeal of standardized plan options, a lower...
Starting in January, new Medicaid work requirements will compel about 20 million low‑income adults in 42 states to log at least 80 hours of work, volunteering, or schooling each month to retain coverage. The rules disproportionately affect middle‑aged adults, especially women...
Tribal health‑insurance programs that rely on ACA premium subsidies are facing a funding crisis after the enhanced tax credits expired at the end of 2025. Premiums have surged, forcing tribes like Fort Peck and Blackfeet to limit enrollment and risk...
BioRestorative Therapies announced completion of patient enrollment for its Phase II BRTX‑100 trial in chronic lumbar disc disease, enrolling 99 subjects at 15 U.S. sites. The double‑blind, sham‑controlled study randomizes participants 2:1 to receive an autologous hypoxically cultured mesenchymal stem cell...
A new wave of eight biotech firms is redefining antibody‑drug conjugates (ADCs) by pursuing unconventional targets, advanced linker chemistries, and novel cytotoxic payloads. Companies such as Adcendo, Adcentrx, and Tubulis are advancing phase 1/2 programs that address sarcoma, Nectin‑4, NaPi2b, and...
In this episode of The Retirement Answer Man, Roger Whitney walks listeners through the three primary health‑care options available before Medicare eligibility: COBRA continuation coverage, ACA marketplace plans, and part‑time employer group insurance, while also noting other alternatives like private...
The episode explores EnGene's experimental gene therapy, detalimogene, for treating non‑muscle invasive bladder cancer, a condition affecting half a million new patients annually. Ron Cooper, EnGene's CEO, explains how the therapy uses a non‑viral vector to deliver a dual payload...
The American Conference Institute will host its 22nd Annual Paragraph IV Disputes Conference on April 21‑22, 2026 in New York’s Times Center. The two‑day forum gathers brand‑name and generic drug stakeholders to discuss Hatch‑Waxman litigation strategies, recent case law, and evolving PTAB practices. Featured...
Home‑based care providers are confronting a fragmented employment‑law landscape, prompting a Polsinelli webinar that outlines urgent compliance steps. Within the next three to six months firms should audit wage, leave and worker classification, verify salary‑range postings, and evaluate AI‑driven recruiting...
Amazon One Medical launched Health Insights, a beta tool that converts routine bloodwork into personalized health information. Developed with Lifeforce, the feature evaluates over 50 biomarkers and delivers a wellness score, domain‑specific analysis, and evidence‑based lifestyle recommendations at no extra...
A JAMA Internal Medicine cohort study of more than 600,000 Medicare hospitalizations found that reinstating the three‑day inpatient rule lengthened stays but did not curb skilled nursing facility (SNF) discharges, improve 30‑day outcomes, or lower Medicare spending. The rule increased...
Dr. Mehmet Oz described alcohol as a “social lubricant” while the U.S. dietary guidelines were revised to eliminate the traditional one‑drink‑for‑women, two‑drinks‑for‑men cap. The updated recommendations now only advise Americans to drink “less,” despite evidence that even low‑level consumption raises cancer...
CMS released a proposed rule for the 2027 ACA marketplaces aimed at curbing rising premiums and stabilizing enrollment after enhanced subsidies expired in 2026. The rule would allow non‑network plans to sell on the exchanges, extend catastrophic coverage terms up...
Researchers at the Miami Itch Center, led by Dr. Gil Yosipovitch, found that nocturnal pruritus spikes due to circadian shifts in cytokines, increased skin permeability, and a modest rise in skin temperature. The study links chronic itch to chronic pain,...
Healing Hearts Changing Minds (HHCM) announced a $566,260 grant program called Walking Each Other Home, supporting seven hospice, palliative and psychedelic care organizations across the United States. The funding will enable clinical trials of psilocybin for brain‑tumor patients, ketamine‑assisted psychotherapy...
The Maryland Maternal Health Innovation Program (MDMOM), funded with $15.8 million from HRSA, is coordinating data, quality improvement, workforce development, and community engagement across all 32 birthing hospitals in the state. Led by Dr. Andreea Creanga, the initiative has instituted statewide...
AdvaMed announced Melissa Torres as its new executive vice president of technology and regulatory affairs, succeeding long‑time leader Janet Trunzo. Torres arrives with more than two decades of FDA leadership, most recently as associate director for international affairs at CDRH....
Mayo Clinic launched an in‑house Nurse Virtual Assistant, a generative AI tool that instantly curates patient records and policy information for nurses. The initiative demonstrates a problem‑first approach, targeting clinician workflow inefficiencies rather than shoehorning technology. The article expands the...
Florida enacted the Sunshine Genetics Act, creating the nation’s first state‑backed newborn whole‑genome sequencing program. The five‑year pilot will offer free opt‑in testing to 100,000 infants, funded by a mix of private and state resources, and establishes a new Institute...
Philips Chief Medical Officer Dr. Carla Goulart Peron outlined the company’s push into digital health, emphasizing expanded CPAP and respiratory solutions integrated with consumer wearables. She highlighted AI’s role in early detection, especially for stroke and women’s heart disease, while...
Senators Josh Hawley and Elizabeth Warren introduced the Break Up Big Medicine Act, a "Glass‑Steagall"‑style bill that would prohibit common ownership of health‑care providers with insurers, PBMs, or drug/medical device wholesalers, forcing divestiture within a year. The legislation targets vertically...
The article warns that reliance on AI tools and GLP‑1 weight‑loss drugs creates shortcut mentalities that weaken the brain’s motivation circuits. Behavior‑change expert Kyra Bobinet argues that these “easy buttons” prevent the iterative learning process that builds lasting competence. She...
Baxter International announced it is cutting roughly 90 positions at its Marion, North Carolina IV solutions plant, representing about 3% of the site’s workforce. The facility, which supplies roughly 60% of U.S. IV fluids, recovered from Hurricane Helene damage but...
Oracle announced new capabilities in its Fusion Cloud SCM suite tailored for process manufacturers. The updates introduce AI‑assisted recipe synchronization, dynamic batch sizing, and granular yield modeling to handle blending, mixing, and batch‑based production. Enhanced traceability features include lot‑specific unit‑of‑measure...
The KFF Health News Minute, a weekly health‑policy briefing, highlighted a range of pressing issues in February. It noted that the expiration of extra Affordable Care Act subsidies is leaving American farmers vulnerable, while hospitals are launching their own Medicare...
CommonSpirit Health at Home announced an aggressive hospice growth plan through 2026 and beyond, prioritizing de novo site launches and selective acquisitions. Leveraging its extensive health system network, the organization will shift upstream by using EHR‑based eligibility triggers to identify...
In this 15‑minute episode, DDW host Bruno Quinney recaps five major stories from the past week, highlighting breakthrough cancer therapies that promise greater efficacy and safety, and new research aimed at enhancing brain function in Alzheimer’s patients. He also touches...
In this episode, Michael Carr, VP and CIO of Health First, discusses the organization’s integrated payer‑provider platform built on Epic’s suite, including the provider rollout and the Epic Tapestry health‑plan implementation. He highlights how consolidating nine disparate systems into a...
The episode announces that CDC’s National Firefighter Registry for Cancer (NFR) has surpassed 40,000 participants, making it the nation’s largest firefighter cohort for studying occupational cancer risk. It explains how the registry gathers detailed work histories and links them to...
Open‑source R is reshaping statistical programming in clinical trials, offering CROs a cost‑effective, flexible alternative to traditional licensed tools. Its extensive package ecosystem, combined with RMarkdown and Shiny, enables rapid automation, interactive reporting, and reproducible workflows. While sponsors are increasingly...
Ambulatory Surgery Center (ASC) owners are increasingly using sale‑leasebacks to unlock the equity tied up in their buildings. By selling the property to an investor and signing a 10‑15‑year triple‑net lease, physicians retain operational control while converting real‑estate assets into...
The Sequoia Project released two practical guides on February 9, 2026 to accelerate automated, computable patient consent across the United States. One guide provides model legislative language to align state‑level sensitive health‑data laws with national technical standards, while the second offers...
The skilled‑nursing sector entered 2026 with strong occupancy and higher state reimbursements, restoring profitability for many facilities. Financing remains robust, but activity has shifted toward acquiring and refurbishing existing homes rather than new construction. Regional operators are snapping up underperforming...
In this episode Edward Corona dissects the sudden 16% plunge of Hims & Hers Health (HIMS), linking it to a dual blow from GLP‑1 hype‑driven expectations and mounting legal and FDA scrutiny. He explains how lawsuits and regulatory pressure are...
Evans Senior Investments brokered the sale of the nonprofit Glencroft Center for Modern Aging in Glendale, Arizona, fetching $30.15 million—about $134,000 per bed—despite a 47% occupancy rate and a 1‑star CMS rating. The deal doubled the seller’s expected proceeds by creating...
The FDA’s new guidance clarifies, rather than rewrites, the line between general‑wellness wearables and regulated medical devices, emphasizing intended use as the decisive factor. By allowing sensor‑rich products to remain unregulated if they avoid medical claims, the agency reduces regulatory...
Healthcare providers are grappling with rising, unpredictable cloud costs as AI‑driven workloads expand. Experts from AWS and Trend Micro stress a hybrid approach, placing latency‑critical patient data on‑premises while leveraging cloud elasticity for analytics and AI training. Successful cost control...
Maine’s state‑run CoverME.gov marketplace reported its lowest enrollment since launch, with 58,523 consumers signing up in 2026 – a 9.5% drop from the previous year. New customer registrations fell 24%, while the share of enrollees receiving Advance Premium Tax Credits...
The Centers for Medicare & Medicaid Services (CMS) issued a regulatory update effective April 13 that expands documentation, face‑to‑face (F2F) and prior‑authorization requirements for Medicare‑covered DMEPOS items. Eight new oxygen‑related codes join the F2F/WOPD list, while seven additional items—five orthoses and...
athenahealth and b.well Connected Health have launched a point‑of‑care workflow that lets patients share their health records digitally via a QR code, eliminating paper forms, faxes, and multiple portal logins. The solution integrates b.well’s patient‑controlled data aggregation with athenaOne, the...
The episode reviews KLAS Research’s 2026 report on comprehensive ambulatory EHR and practice‑management (PM) suites, revealing that integration of clinical and financial workflows is the top driver of satisfaction for ambulatory organizations. The study of 176 providers shows 71% value...
The article argues that relying on "at‑the‑elbow" support to compensate for clunky telehealth platforms hides deeper usability problems. It highlights how bundled EHR video tools often lack essential workflow integration, forcing organizations to spend on training, staffing, and workarounds. These...
The episode dissects a misleading chart promoted by the Paragon Health Institute that Senate Majority Leader John Thune used to argue against extending ACA subsidies, claiming Obamacare premiums have skyrocketed. Health policy experts, including Brookings senior fellow Matthew Fiedler, explain that the...
The healthcare industry still relies on geofencing, which ties patient records to a specific geographic zone, hindering data continuity when patients relocate. This limitation clashes with the push toward national interoperability championed by TEFCA and CMS frameworks. Experts argue that...
The article argues that designing products and services with disability in mind catalyzes broader innovation. It cites early examples like the Safety Tub walk‑in bathtub, showing how solutions for seniors sparked new market categories. The authors, a mix of academic...
Amprion Diagnostics has commercialized a seed‑amplification assay, SAAmplify‑αSYN, that detects misfolded alpha‑synuclein in cerebrospinal fluid, earning FDA breakthrough‑device status in 2019. The test can identify Parkinson’s, Lewy‑body dementia and up to half of Alzheimer’s cases years before clinical symptoms appear....
