Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves first CIRM‑funded gene‑editing therapy for rare immune disorder
The FDA has granted approval to KRESLADI, a gene‑editing therapy from Rocket Pharmaceuticals that treats severe leukocyte adhesion deficiency‑I in children without a matching bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine (CIRM), highlighting the agency’s impact on translational research.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
Wayne State University researchers deployed mobile health units across Detroit from July 2022 to August 2025, evaluating 5,128 adults in 5,973 encounters. The screening revealed that 44.7% had mildly decreased eGFR and 11.3% met criteria for stage‑3 or worse chronic kidney disease, rates notably higher than national averages. Partnering with Ford Motor Company, the program demonstrated that placing testing infrastructure in high‑risk neighborhoods can uncover undiagnosed CKD, especially among older, Black, and diabetic patients. The authors suggest that population‑wide mobile screening could close care gaps and support cost‑effective early intervention.
At the 2026 American Academy of Dermatology meeting, phase 3 ADORING 1 and 2 trials demonstrated that once‑daily tapinarof cream significantly improves rash and itch in moderate to severe atopic dermatitis, with effects evident by week 1 and sustained through eight weeks. The studies...
Hydrosil Dry Eye Gel, priced at £9.56 (≈ $12), is gaining traction among hay‑fever sufferers seeking relief from itchy, dry eyes. The gel’s gentle, barrier‑supporting formula delivers lasting moisture without triggering additional irritation, making it suitable for sensitive skin around the...
The Society of Vascular Surgery is pushing a heart‑team model that brings vascular surgeons into peripheral artery disease (PAD) discussions, enabling earlier diagnosis and broader treatment options. Dr. William Shutze notes that involving surgeons can shift patients from “no‑option” status...
Ruxolitinib cream (Opzelura) demonstrated significant facial repigmentation and quality‑of‑life gains in vitiligo patients, especially those reaching F‑VASI75/90 thresholds, according to post‑hoc analyses of the TRuE‑V trials presented at the 2026 AAD meeting. Real‑world survey data revealed that just over one‑fifth...
In 1992, scientists discovered a chemical in Gila monster venom that mimicked GLP-1, the hormone your gut releases to signal fullness. By tinkering with its structure, pharma companies extended its duration from two hours (the Gila monster version) to one...
Why Does My Elbow Hurt So Much? Tennis elbow affects 1–3% of the population at any given time. Over a lifetime, virtually everyone will experience it. The vast majority of people who develop it have never played tennis. They are carpenters,...
In a recent FDA Q&A, Dr. Sarah Yim explained that the agency has now approved 50 biosimilars covering 15 reference biologics, spanning treatments from oncology to diabetes. She clarified the distinction between biosimilars and interchangeable biosimilars, noting that the latter...
A Monash University-led study of 545 Australian three‑ and four‑year‑olds found 43% meet criteria for an anxiety disorder, with 31% showing specific phobias. Researchers caution the findings are preliminary but say they highlight a growing mental‑health concern that could reshape...
Pharma firms are leveraging real‑world data (RWD) to map the patient journey of non‑small cell lung cancer (NSCLC) and uncover social determinants of health that hinder care. The new eBook highlights how gaps in biomarker testing, socioeconomic barriers, and incomplete...
A peer‑reviewed eight‑week trial of Dzeny’s AI therapist showed a 43% drop in GAD‑7 anxiety scores, matching traditional CBT effect sizes. At the same time, New York‑based Blossom Health closed a $20 million seed/Series A round to roll out its AI “copilot”...
Akeso Inc. announced a 51.5% year‑on‑year increase in 2025 commercial sales to RMB3.033 bn (about $425 m) and secured Chinese regulator clearance to launch Phase II trials of two first‑in‑class antibody‑drug conjugates. The results underscore the biotech’s rapid commercial expansion and its strategic...
A reported case of a patient being denied insurance coverage for a medically diagnosed condition cannot be substantiated with the provided sources. No specific numbers, parties, or quotes are available, and details were not disclosed.
More than 2,750 American doctors, nurses and researchers have applied for positions in Canada, spurred by U.S. federal funding cuts and restrictive abortion laws. British Columbia’s targeted recruitment campaign has already secured 400 hires, while a volunteer‑run social‑media movement fuels...
St. Louis‑based SSM Health co‑owns Navitus Health Solutions, a pharmacy‑benefit manager serving 18 million members across 800 clients nationwide. Navitus differentiates itself with a fully transparent, pass‑through pricing model that avoids hidden mark‑ups and spread pricing. The approach comes as Congress...
The BIO Europe Spring podcast recorded in Lisbon highlighted Europe’s push to reclaim biotech leadership amid dominant US and Chinese pharma giants. Host Robert Barrie distilled insights from investors and executives, emphasizing the continent’s strategic focus on gene‑therapy and mRNA...
Hospitals face tighter budgets, staffing shortages, and rising drug costs, prompting a search for more efficient medication management. RFID technology, once limited to retail, now offers real‑time, item‑level tracking that reduces manual errors and streamlines documentation. Advances in ultra‑high‑frequency tags...
On March 27, 2026 BioWorld reported a flurry of regulatory actions affecting a broad swath of biopharma and med‑tech companies. The snapshot lists approvals, designations and submissions for firms such as 3D Systems, Agilent, Deciphera, Royal Philips and several others....
Johnson & Johnson’s Darzalex (daratumumab) received European Medicines Agency approval for self‑administration, becoming the first oncology injectable cleared for home use. The Type II label change allows patients or caregivers to give the subcutaneous injection after the fifth dose, covering all...
A young soldier returning to Texas after a two‑week stay in Puerto Rico developed high‑grade fever, retro‑orbital headache, a diffuse maculopapular rash with petechiae, thrombocytopenia and mild liver enlargement. Laboratory findings showed leukopenia and a platelet count of 50,000, and...
CareTria’s CEO Willis Chandler told Pharmaceutical Commerce that 50% of patients abandon specialty drugs due to fragmented support and lengthy benefit verification. The company’s automated platform unifies provider, pharmacy, and payer workflows, slashing the time from prescription to therapy from...
Boston Children’s Hospital deployed Etiometry’s AI‑driven clinical intelligence platform to capture continuous high‑frequency physiologic data across its pediatric ICU. The system aggregates and visualizes signals in real time, giving clinicians a shared, longitudinal view of each patient’s trajectory. Early results...
The SaaS-pocalypse playing out in public stocks reflects a real fear. Legacy SaaS companies, even with their existing distribution and install base, may be unsuccessful in bolting on AI capabilities to their legacy platforms. There is fear that their user...
A health system’s new virtual‑care program let a former CIO schedule a same‑day appointment, complete intake via an app, and see a physician in a 15‑minute video visit. The experience showcased rapid, real‑time scheduling and thorough clinical interaction, proving virtual...
Artificial intelligence has moved from pilot projects to core clinical tools, with the FDA authorizing more than 1,400 AI‑enabled medical devices by the end of 2025, most via the fast‑track 510(k) pathway. Radiology dominates usage, but AI is expanding into...
AnaptysBio announced the spin‑out of its biotech operations into a newly formed independent public company, First Tracks Biotherapeutics. The separation isolates AnaptysBio’s early‑stage pipeline, giving First Tracks a focused platform to advance its candidates. The announcement also highlighted promising data...
Is sun avoidance a risk factor for mortality?☀️ In this 2014 study from Sweden, sun avoidance was associated with nearly a 2x higher rate of all-cause mortality compared to the most active sun exposure habits. They did find increased risk of malignant...
Vida Health has introduced a Metabolic Control Framework that shifts from isolated disease programs to a population‑level strategy for obesity, diabetes, hypertension, hyperlipidemia, MASH, OSA and COPD. The framework relies on a proprietary Metabolic Control Index, which aggregates clinical, biometric...
Milestone Pharmaceuticals received FDA approval on December 12, 2025 for CARDAMYST, a 70 mg nasal spray of etripamil designed to rapidly convert acute paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm. The pivotal RAPID trial enrolled 255 adults across eight countries, showing...
Long‑time SSRI user Elizabeth, 64, was instructed to stop Celexa abruptly and start Zoloft, triggering severe emotional, sensory, and cardiac symptoms. Her experience illustrates how rapid tapering can lead to protracted withdrawal, a condition often misdiagnosed as a new depressive...
Healthcare vendors are rolling out a suite of AI tools aimed at streamlining billing, coding, imaging, and fraud prevention. CentralReach’s AI agents cut revenue‑cycle work by up to 40%, while Innovaccer’s Flow Capture autonomously codes roughly 80% of patient encounters....
Digital health developers are being urged to embed nurses, physicians, and patients directly into the design process, a stance championed by Susan Hull, the HIMSS‑ANI Nursing Informatics Changemaker honoree. Hull argues that tools built without real‑world clinical input often miss...
In 2026, six hospitals across the United States will end or relocate their labor and delivery services, adding to the 29 maternity unit closures reported in 2025. The facilities—spanning West Virginia, Kentucky, Indiana, Tennessee, Iowa, and Arkansas—cited chronic staffing shortages,...
UCLA Health has appointed Katherine Andriole, PhD, as the inaugural associate dean for health AI strategy and innovation at the David Geffen School of Medicine, effective March 26. She also assumes directorship of the UCLA Center for AI and SMART Health....
#Measles update: #CDC reports the confirmed case total this year to date is 1,575 — or 69% of the number of cases in the entirety of 2025. That's up 88 from last week. 94% of the cases are parts of...
.@flexpa is integral to enabling the AI-powered healthcare system currently being built. and we're ready for all of it.
AI adoption in healthcare and life sciences is surging, with physician usage climbing to 66 % and firms investing heavily in machine‑learning platforms. Despite this momentum, a reproducibility crisis looms, as more than 70 % of researchers report difficulty replicating results, jeopardizing...
Patients aren't turning to AI because they trust it more than their doctors. They're turning to it because their questions don't stop between appointments. First piece on Substack: https://t.co/OciXwTtxM1
Healthcare wants AI in revenue cycle, but adoption is lagging. 67% have high hopes. Only 14% have implemented it. Why? Data quality and workflow trust. Insights from Experian Health + Integris Health 👇 https://t.co/SdtyNSwza6 @Experian_Health #IntegrisHealth #AIinRCM #HITSM
Major cardiovascular societies, led by the ACC and AHA, released a consensus document outlining requirements for establishing and maintaining transcatheter tricuspid valve intervention (TTVI) programs in the United States. The guidance sets minimum institutional volumes—such as at least 50 open‑heart...
AstraZeneca lung drug gets ‘surprise’ win in COPD trials https://t.co/QuRlOQtzdT @ByJonGardner $AZN $RGN $SNY $RHHBY
Could a simple blood test predict your risk of getting #Alzheimers dementia years, or even decades, before you experience memory loss? https://t.co/oLROODZbFz
Xavier University in Cincinnati will launch the world’s first Jesuit osteopathic medical school in fall 2027 after a $2 million gift from alumni Gary and Connie Sharpe, split with a new nursing program. Ground was broken in 2024 for a 130,000‑square‑foot...
Novartis targets Xolair successor in buyout of startup Excellergy https://t.co/eGYQ2AxTd5 by @gwendolynawu $NVS $RHHBY #startups #biotech
Kudos to @UCLAHealth for assessing genomics of their patient population, published @CellCellPress today. But why weren't the results of increased polygenic risk scores (PGS) provided to the patient participants? https://t.co/F15isJfDQy https://t.co/3AW7peHa1C
NYC Health + Hospitals has launched a $2.75 million program deploying PeriWatch Vigilance, an AI‑driven early‑warning and decision‑support system for maternal‑fetal care. The tool, currently active at the North Central Bronx hospital, will be expanded to all 11 system hospitals by...
Now at 1M+ views. What struck me most here wasn’t the views. It was the engagement. People are ready to engage seriously with aging biology. Now the opportunity is to turn that energy into stronger collaboration, better translational science, and...
Half of U.S. med students are women. But some specialties still haven’t caught up. Heading to the Women in GI Conference in Atlanta where I’ll serve on the faculty. Honored to be in the minority. Representation isn’t just about fairness. It’s about better...
A wave of senior appointments is reshaping hospice leadership across the United States. Montgomery Hospice named longtime hospice operator Sara McKay as COO, while VITAS Healthcare installed Juan Gomez as VP of Finance after a stint in revenue‑cycle management. Three Oaks Hospice...
Benadryl (diphenhydramine) is an over‑the‑counter antihistamine that also acts as an anticholinergic, causing drowsiness and other side effects, especially in older adults. Observational studies link long‑term high anticholinergic exposure to increased dementia risk, though causation remains unproven. The drug appears...
