Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
Novartis announced it will pay up to $2 billion upfront to acquire Excellergy Inc., securing the biotech’s next‑generation anti‑IgE candidate. The move comes as Xolair, Novartis’ blockbuster allergy drug, prepares for imminent biosimilar competition that could erode its market share. By adding Excellergy’s high‑affinity, long‑acting antibody, Novartis aims to refresh its allergy portfolio and sustain revenue streams. The acquisition underscores the company’s strategy to invest heavily in innovative biologics to offset upcoming patent cliffs.
Worki, an AI‑driven workforce platform, targets the 34% of health‑system overhead tied to non‑clinical roles by unifying fragmented HR systems and deploying intelligent agents. The solution offers a phased, data‑backed pathway that can deliver 20% or more cost reductions, projecting...
CompHealth’s advanced practice, therapy, and laboratory staffing division has earned the Health Care Staffing Services (HCSS) Certification from the Joint Commission, the nation’s leading independent health‑care accreditor. The certification confirms compliance with rigorous national safety and quality standards and was...
WEX Inc. launched a specialized Health Reimbursement Arrangement (HRA) to help employers manage the soaring costs of GLP‑1 medications, which are now used by an estimated 34 million Americans for weight management. The solution lets companies allocate a fixed contribution for...
A University of Illinois study found that more than 98% of full‑time wheelchair and scooter users worry about falling, and 68% reported a fall‑related injury in the past year. Researchers created the Fall Concerns Scale, a device‑specific tool that captures...
Recursion Therapeutics announced the appointment of Vicki Goodman as its new chief medical officer, bringing her extensive oncology and drug‑development experience from a decade as CMO at Exelixis. Goodman will oversee clinical strategy for Recursion’s AI‑driven pipeline, aiming to accelerate...
Researchers at UCLA Health and Stanford Medicine reported that a neoadjuvant regimen combining hypofractionated radiation, the experimental immunomodulator BO‑112, and anti‑PD‑1 therapy (nivolumab) can reshape the tumor microenvironment of soft‑tissue sarcoma. Preclinical mouse work and a Phase I trial in 14...
The article argues that extending healthspan—years lived in good health—should eclipse the pursuit of sheer longevity. It highlights the growing gap between longer lifespans and rising chronic disease burdens, urging a shift toward interventions that improve quality of life. Researchers...
Researchers at UC San Diego introduced the MetALD‑ALD Prediction Index (MAPI), a biomarker panel that leverages routine blood tests to differentiate alcohol‑associated liver disease from metabolic steatotic liver disease. In a 503‑patient US cohort, MAPI achieved 60% sensitivity, 80% specificity,...
The heart oxygenates itself first. The first branches of the ascending aorta are the left and right coronary arteries. Yet the culture of medicine actively trains physicians to do the exact opposite. In a recent conversation on The Podcast by KevinMD, integrative...
The Queensland Crisafulli government announced a sweeping overhaul of its public health service boards, adding 50 new members. Among the appointees are former LNP MP Darren Zanow to the West Moreton board, Cairns candidate Yolonde Entsch to the Torres and Cape...
AstraZeneca announced that its investigational COPD antibody achieved positive results in two Phase 3 trials, marking a turnaround after a previous mid‑stage failure. The studies demonstrated statistically significant improvements in lung function and exacerbation rates across a broader patient population...
As a medical school professor, I teach my students to prescribe drugs. But a landmark review in Cell Metabolism argues we should prescribe exercise first. Febbraio and Pedersen -- the scientists who coined "exercise as medicine" -- reviewed 233 studies on...
The World Health Organization announced that more than 60 countries—two‑thirds of the 93 surveyed—have incorporated refugees and migrants into their national health policies. The new WHO report establishes the first global baseline for tracking inclusive, migrant‑responsive health systems, signaling a...
A joint analysis of the Women’s Health Initiative and the All of Us Research Program, covering roughly 222,000 men and women, shows that the highest intake of several B‑vitamins is associated with up to a 20 percent lower incidence of stroke....
The UK government has issued new guidance limiting screen time for children under five to one hour per day, with stricter rules for under‑twos. The advice, backed by health experts, urges “screen swaps” and joint viewing, while parents grapple with...
As a medical school professor, I was trained to focus on WHAT patients eat. But this massive meta-analysis says WHEN may be just as important. 41 randomized controlled trials. 2,287 participants. Published in BMJ Medicine. The finding: time-restricted eating improved nearly every...
Human Longevity, Inc. and the LEV Foundation announced a strategic partnership to analyze blood samples from centenarians and supercentenarians. The collaboration will use HLI's AI‑driven precision longevity platform and LEV’s expertise in lifespan extension to uncover molecular drivers of exceptional...
Novo Nordisk announced that the U.S. Food and Drug Administration has approved Awiqli (insulin icodec-abae), the first and only once‑weekly basal insulin for adults with type 2 diabetes. The approval follows the ONWARDS phase 3a trial program involving roughly 2,680 patients and...
A preclinical study in Small describes an inulin‑butyrate nanogel that releases butyrate directly in the inflamed colon of mice, markedly improving colitis outcomes. The nanogel remains stable through the upper GI tract and is enzymatically activated by colonic microbes, delivering...
Hyman, Phelps & McNamara (HPM) announced a vacancy for a 3rd‑to‑6th year associate attorney on its drug development team. The role supports clients through the full FDA pre‑market lifecycle, from pre‑IND strategy to IND, NDA/BLA submissions and dispute resolution. Candidates...
Hims & Hers announced it will stop actively marketing compounded GLP‑1 drugs and focus on a broader portfolio of FDA‑approved, branded GLP‑1s through a new partnership with Novo Nordisk. The pivot follows a 70% stock plunge and aims to sustain...
South Korean AI firm Neurophet has signed a memorandum of understanding with the Alzheimer’s Network for Treatment and Diagnostics (ALZ‑NET) to build an imaging‑monitoring infrastructure for emerging Alzheimer’s therapies. The deal brings Neurophet’s FDA‑cleared tools—Aqua, Scale PET, and Aqua AD...
It was a pleasure to participate in the Investment and Innovation Pathways to a Healthy Asia session at the Global Investors’ Symposium in Hong Kong. A timely discussion on where durable value is being created in healthcare across Asia, from prevention...
The U.S. Department of Justice has filed an antitrust lawsuit against NewYork‑Presbyterian Hospital, alleging the health system leverages its 30% Manhattan market share to compel insurers into costly, all‑or‑nothing contracts. The suit says the practice inflates premiums for millions of...
Legion Health, a Y Combinator‑backed startup, launched an AI‑driven bot that can renew select psychiatric medications for patients in Utah for a $20 monthly fee. The service, the first in the U.S. authorized to let AI prescribe mental‑health drugs, begins...
myTomorrows, a Dutch health‑tech firm, has partnered with Spain’s Clínica Universidad de Navarra (CUN) to embed an AI‑driven clinical‑trial matching engine directly into CUN’s electronic health record. The system leverages large language models to parse multilingual unstructured notes and structured...
A multidisciplinary team at Washington University in St. Louis implanted nanodiamond quantum sensors inside living mouse cells and recorded real‑time magnetic and temperature fluctuations from mitochondria. The breakthrough, presented at the March 16, 2026 APS meeting, demonstrates a new route...
Simulations Plus has launched strategic partnership programmes with three pharmaceutical companies to embed AI‑driven modelling into the drug development lifecycle. The collaborations will integrate Simulations Plus platforms—ADMET Predictor, GastroPlus, Thales and MonolixSuite—into model‑informed drug development (MIDD) workflows, enabling natural‑language interaction and automated...
Zhongzhi Pharmaceutical Holdings Limited announced a full‑year 2025 net profit of RMB17.29 million ($2.4 million), an 82% plunge from the previous year, while revenue dropped 21.5% to RMB1.737 billion ($243 million). The sharp contraction underscores growing pressure on Chinese drug makers amid a tightening...
A new population study in The Lancet Healthy Longevity found that older adults who experience delirium during a hospital stay face a three‑fold higher risk of developing dementia later, even if they entered the hospital with few or no chronic...
The 31st Annual Executive War College will convene April 28‑29 in New Orleans, bringing together clinical laboratory executives to address reimbursement, staffing, compliance, and emerging technologies. A new Executive Forum on Digital Pathology Management will spotlight AI‑driven workflows and data...
The West Hancock Ambulance Service, a volunteer‑run EMS provider serving Britt and surrounding Iowa towns, marked its 50th anniversary with a community celebration on July 19. Founded in early 1976 after local funeral homes ended ambulance operations, thirteen residents pooled...
The pharmaceutical industry faces commercial risk as it prepares for the 2033 transition to a uniform 12‑digit NDC format, with experts warning that thousands of zero‑prefix collisions could trigger PBM claim rejections, disrupt patient‑hub enrollments, and corrupt market‑intelligence data. Simultaneously,...
In this episode, Dr. Zev Neuwirth, a veteran physician and healthcare strategist, explains why the U.S. health system is fundamentally broken, pointing to the collapse of primary care, soaring administrative costs, and the failures of employer‑based insurance. He argues that...
Primary care physicians handle a wide range of everyday health issues, from respiratory infections to chronic disease screening. The article outlines nine common conditions they treat, emphasizing early detection and continuity of care. It highlights how primary care can spot...
An 18‑month strength‑training trial involving 377 knee‑OA patients boosted hip‑abductor, hamstring and quadriceps strength but did not lower knee joint loading or pain. A post‑hoc analysis of the 88 strongest responders confirmed significant muscle gains—45% in quadriceps, 68% in hamstrings,...
MediClin: 2025 revenue +4.8% to €784.5m, EBIT +3.5%. Drivers: post‑acute growth, stable occupancy; acute fell after Heart Centre sale. Risk: narrow 2026 EBIT range. Buy, watch 2026 EBIT. — Viktor Kopylov, PhD, CFA. More insights: t.me/si14Kopylov
MIT researchers discovered that three widely used anesthetics—propofol, ketamine and dexmedetomidine—produce an identical destabilization of brain dynamics, measurable as a loss of dynamic stability. Using EEG‑based perturbation analysis, they showed that despite distinct molecular targets, each drug pushes the brain...
HaemaLogiX, an Australian clinical‑stage biotech, is developing precision immunotherapies for multiple myeloma by targeting novel antigens KMA and LMA that appear only on malignant plasma cells. Peer‑reviewed research validates these targets, allowing the company to spare healthy plasma cells and...
The Trump administration touts recent reductions in Affordable Care Act (ACA) enrollment fraud while unveiling a sweeping set of 2027 regulations aimed at tightening eligibility verification and curbing broker misconduct. Complaints about unauthorized enrollments climbed to 341,906 in 2025, prompting...
Northwestern Medicine has upgraded its mobile stroke unit (MSU) with a 32‑slice CT scanner, replacing the older 16‑slice system. The new, smaller‑footprint vehicle can perform advanced imaging en route, allowing clinicians to differentiate ischemic from hemorrhagic strokes before hospital arrival....
Wearable devices have moved beyond consumer hype, offering concrete value for healthcare providers. The article outlines five practical pathways—remote patient monitoring, EHR integration, patient engagement tools, security/compliance foundations, and focused use‑case design—to embed wearable data without overhauling existing IT stacks....
A cross‑sectional analysis of 4,118 U.S. adults aged 20‑69, published in *Neurourology and Urodynamics*, found that overactive bladder (OAB) is independently linked to a higher recent‑fall risk. OAB prevalence was 19.6% while 28.3% of participants reported a fall in the...
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The Rockefeller Foundation’s new report projects that expanding Food Is Medicine programs to the 43 million Americans with diet‑related conditions could generate roughly $45 billion in economic activity, create 316,000 jobs, and funnel more than $5.6 billion to small and mid‑size farms. Medically...
Abcuro presented Phase II/III MUSCLE trial data for ulviprubart (ABC008) in inclusion body myositis (IBM) at the GCOM 2026 meeting. The study enrolled 272 patients who received either 0.5 mg/kg, 2 mg/kg, or placebo. Across the entire cohort the drug showed only...
Efficacy of Alpha-Lipoic Acid in Patients With Ischemic Heart Failure: A Double-Blind, Randomized, Placebo-Controlled Study | @JACCJournals https://t.co/nW9SbwEDfy https://t.co/qsemjmMb9k
Phio Pharmaceuticals (NASDAQ:PHIO) and Galectin Therapeutics (NASDAQ:GALT) are small‑cap biotech stocks compared across nine investment factors. Phio enjoys stronger institutional backing (57% vs 12%) and a higher consensus target price of $14, implying over 1,000% upside, while Galectin’s target is...
On March 5, 2026, HL7 International launched the Caliper FHIR Accelerator, an implementation community aimed at real‑time medical device data interoperability. The initiative builds on HL7’s 2025 device‑workgroup and aligns with standards from IEEE, ISO, IEC, and IHE. By extending...
