Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
A retrospective cross‑sectional study of 13,638 Chinese adults found that the combined triglyceride‑glucose and body shape index (TyG‑ABSI) is linearly associated with atherosclerotic cardiovascular disease (ASCVD). Each unit increase in TyG‑ABSI raised the odds of ASCVD by 152 % (OR 2.52). TyG‑ABSI outperformed traditional TyG‑based indices, achieving an AUC of 0.718. Inflammatory and oxidative‑stress biomarkers partially mediated the relationship, while adherence to Mediterranean, DASH or HEI‑2020 dietary patterns attenuated the risk.
Researchers evaluated the atherogenic index of plasma (AIP) as a prognostic marker in 314 patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). Over a median 29‑month follow‑up, each 1‑unit increase in pre‑operative AIP was linked to a...
A retrospective cohort of 119 lung‑cancer patients treated with immune checkpoint inhibitors identified sarcopenic obesity (SO) in 15% of cases. Patients with SO experienced the shortest median overall survival (22.6 months) and a three‑year hazard ratio of 3.48 for mortality,...
A new bibliometric study maps the evolution of preoperative carbohydrate loading (PCL) research, analyzing 269 publications from 38 countries up to March 2025. China produced the most papers, while England occupied the most central position in international collaboration networks. The...
A prospective cohort of 300 patients aged 65+ with fragility hip fractures examined how adherence to oral nutritional supplements (ONS) affected mortality. Patients who consistently retrieved ONS for at least three months showed a markedly lower 12‑month death rate (15.2%)...
Your ankle is a window into your heart. A new study found that patients with a thickened Achilles tendon were nearly twice as likely to experience a major cardiovascular event within three years of a coronary stent procedure. An observational study...
New Zealand’s government has launched the second of four rural health training hubs in Wairoa, aiming to attract and retain frontline health staff. The hub will coordinate clinical placements, training pathways, and provide pastoral support such as housing and employment...
HRadiO’s latest episode spotlights Dr Patrick Maguire, co‑founder of Beecroft Animal Specialist & Emergency Hospital, as he shares leadership lessons from veterinary medicine. He argues that upcoming Veterinary Practice Bill regulations will elevate professionalism, accountability, and public trust rather than add...
AI is rapidly improving at reading medical images. But the real question is not whether it will replace radiologists. Most experts see AI becoming a powerful co-pilot: spotting patterns faster, flagging anomalies earlier and helping radiologists focus on complex diagnoses and...
New tissue models could help researchers develop drugs for liver disease by Anne Trafton @MIT Learn more: https://t.co/hkeRZ0W47B #HealthTech #EmergingTech #TechForGood #Innovation https://t.co/LNvft8iX9M
Vantive executive Paul Uthaichalanond highlighted Vietnam's dialysis bottleneck, noting only 5‑10% of roughly 800,000 ESRD patients receive therapy and that 80% of treatments rely on overcrowded hemodialysis centers. He contrasted this with Thailand’s successful “PD‑first” approach, which reduced costs and...
Isaac Health, a telehealth platform for brain health and dementia, announced a partnership with NYU Langone Health, adding a major health‑system channel to its primarily payer‑focused model. The collaboration creates an integrated referral pathway that combines virtual specialty care with...
Well yes, another pandemic is likely, we’ve had a dozen in this new century for reasons I’ve detailed in my 2021 book, Preventing the Next Pandemic @JHUPress it’s demoralizing to watch corrupt organizations exploit this for their financial gain, imagine...
Ascension, a 97,000‑employee health system, is demanding faster, more reliable home‑health services from partner agencies. The system requires same‑day or next‑day visits, referral acceptance within minutes, and acceptance rates above 85%, far higher than the industry average. To improve coordination,...
Capricor Therapeutics reported fourth‑quarter 2025 revenue of $16 million, a modest 4% year‑over‑year increase, while gross margin rose to 86% driven by higher selling prices and manufacturing efficiencies. Net loss widened to $11.9 million as operating expenses outpaced revenue growth, but the...
The Oncology Institute reported Q2 2025 revenue of $119.8 million, a 21.5% year‑over‑year increase, driven by a 41% surge in pharmacy sales that now represent 52% of total revenue. Gross profit rose 34% YoY while SG&A fell to 22% of revenue,...
Champions Oncology reported $14 million revenue in Q1 FY2026, flat year‑over‑year and rebounding from a $12.4 million Q4 dip. GAAP operating loss widened to $0.5 million, while adjusted EBITDA turned slightly positive at $60 000. Gross margin slipped to 43% as outsourced radio‑labeling costs...
Vertex Pharmaceuticals reported Q4 2025 revenue of $3.2 billion, a 10% quarterly increase, and $12 billion for the full year, up 9% year‑over‑year. Gross margin reached 85.7% and non‑GAAP net income rose 24% to $1.3 billion, underscoring strong profitability. New product...
Nektar Therapeutics reported strong Q4 2020 results, highlighting robust progress on its cytokine platform. The IL‑2 agonist BEMPEG demonstrated a median progression‑free survival of 30.9 months in melanoma and is now enrolled in six registrational trials across melanoma, renal, bladder,...
The Trump administration announced that the Department of Justice will grant the Veterans Affairs (VA) department authority to initiate guardianship proceedings for veterans deemed unable to make health‑care decisions. The policy targets homeless veterans and those without family, allowing state...
Researchers at Harvard’s Wyss Institute and Dana‑Farber unveiled DoriVac, a DNA origami‑based vaccine platform that delivers antigens and adjuvants on a self‑folding nanostructure. In pre‑clinical mouse studies and a human lymph‑node‑on‑a‑chip model, DoriVac generated antibody and T‑cell responses comparable to...
The BMJ rapid response argues that environmentally sustainable prescribing of diabetes medication must extend beyond the waste generated by GLP‑1 agonist pens. It details how the chemically intensive production of peptide drugs and the disposable nature of insulin pens, pumps...
Vima Therapeutics announced an additional $40 million raise, taking its Series A funding to $100 million. The capital will support parallel Phase 2 trials of its lead candidate VIM0423 in isolated dystonia and Parkinson’s disease, expanding the startup’s focus beyond the rare movement disorder....
Yes @JReinerMD and they left out how how >200,000 Americans died needlessly bc they refused Covid vaccinations in 2021-23. Victims of an organized antivaccine disinformation campaign, now being repeated in this new version of HHS
Carrum Health and Virta Health announced a partnership delivering a full‑spectrum weight‑management solution for self‑insured employers. The collaboration links Carrum’s value‑based surgical care with Virta’s virtual nutrition coaching, medication management and GLP‑1 prescribing. It creates a seamless pathway from conservative...
The New York Blood Center opened a 4,000‑square‑foot donor center in the Throggs Neck Shopping Center, marking its first facility in the Bronx and the 21st in the Tri‑State area. The ribbon‑cutting ceremony featured Bronx Borough President Vanessa Gibson and local officials....
The Moving Forward Nursing Home Quality Coalition piloted an on‑call coaching model paired with Quality Assurance and Performance Improvement (QAPI) and leadership training in four low‑rated, high‑Medicaid facilities in Michigan. At Fountain Bleu, hospitalizations dropped from 60% to 22% and...
The skilled‑nursing market saw several high‑profile transactions this week. Excelsior Group acquired the 280‑bed Union Plaza Care Center in Flushing, New York for $75 million, while Selectis Health agreed to sell its two Georgia facilities—Glen Eagle and Eastman Healthcare—totaling 201 beds...
The FDA placed a clinical hold on Regenxbio’s RGX‑111 and RGX‑121 gene‑therapy trials after a pediatric MPS I patient developed a tumor four years post‑treatment. The case marks the first documented long‑latency cancer linked to an adeno‑associated virus (AAV) vector in...
EAA241 - Ph 2 RCT Dara-Bor-Dex vs Cy-Bor-Dex in the treatment of Newly Diagnosed Multiple Myeloma with Light Chain Cast Nephropathy (LCCN) [Study activated 8/11/25] @keruakous https://t.co/1NgvVZ3fTA #NCT07085728 #mmsm @eaonc https://t.co/IvK3UNeem9
#EAonc EAA173 - Daratumumab to Enhance Therapeutic Effectiveness of Revlimid in Smoldering Myeloma (DETER-SMM) - PI: @nsc_natalie https://t.co/VtBMJUjI5X Activated: Apr 30, 2019 #mmsm @eaonc #NCT03937635 @VincentRK @mweissmdphd https://t.co/ikQKjHjscU
A recent report reveals that Medicare Advantage (MA) overpayments are driving higher premiums for traditional Medicare beneficiaries. The analysis shows that excess payments to private MA plans have been passed on to the broader Medicare pool, inflating costs for all...
.@SWOG S2213 Ph3 RCT Dara-VC Induction Followed by ASCT or Dara-VCD Consolidation & Daratumumab Maintenance in Pts w/ Newly Diagnosed AL Amyloidosis [Activated: 12/1/23] https://t.co/OizUfJCc2c #mmsm #bmtsm https://t.co/FoT3i0xGcL
Genomic landscape of multiple myeloma and its precursor conditions [May 21, 2025] Jean-Baptiste Alberge et al. @IrenemGhobrial @NatureGenet https://t.co/DDWGRrpI4Y #mmsm #PrecisionMedicine #cagenome https://t.co/LY1MzFXSBN
Forj Medical, a global medtech CDMO, announced the leadership team for its new advanced manufacturing plant in Tacares de Grecia, Costa Rica. The 53,000‑square‑foot facility, completed in December 2025, will assemble complex medical devices for surgical navigation, electrophysiology, diabetes, cardiovascular...
Multimodal antigenic escape to GPRC5D-targeted T cell engagers in multiple myeloma [Jan 15, 2026] @hollyleeYJ et al. @NBahlis @NatureMedicine https://t.co/mz393mPMAq #mmsm #PrecisionMedicine #tcellrx THREAD: https://t.co/lNX9b7LsnR HT @AuclairDan https://t.co/2qih7LwP1c
Duplicate patients. Broken workflows. Support tickets piling up. Bad identity matching quietly destroys healthcare software. Learn the warning signs → Download the free eBook 🔗 https://t.co/SJg2gLlUzK @rhapsodyhealth #healthcareSaaS #HITSM https://t.co/fTTcYnGhHM
A coalition of SNAP recipients has filed a lawsuit to block sugary‑drink bans in five states, arguing that the Trump administration overstepped its authority under the federal food‑assistance program. The plaintiffs contend that recent policy changes violated statutes governing SNAP...
⏳For too many, aging is a long series of painful losses that ends in a slow, brutal defeat💀 🧪Support geroscience, the biology of aging with potential to prolong healthspan. 📢Demand proactive, preventive longevity medicine for all👨⚕️🩺 https://t.co/Z2x069KI3t
Three‑year follow‑up of the AGENT IDE trial shows the Agent paclitaxel‑coated balloon (DCB) outperforms uncoated balloon angioplasty in treating in‑stent restenosis (ISR), with target‑lesion failure (TLF) rates of 32.7% versus 40.9% (hazard ratio 0.72). The advantage is driven mainly by...
At the 2026 HIMSS Global Health Conference, former VA deputy CIO Nathan Tierney warned that traditional leadership playbooks are failing amid intersecting financial pressures, workforce instability, cyber risks, and rapid tech change. He highlighted how executives often substitute endless meetings,...
Sonex Health and the Institute of Advanced Ultrasound Guided Procedures published a manuscript in the Journal of Ultrasound Medicine confirming that ultrasound‑guided carpal tunnel release (UGCTR) is as effective as traditional open or endoscopic surgery while offering superior patient comfort...
Elutia Inc. reported its Q4 and full‑year 2025 results, highlighting the $88 million sale of its BioEnvelope business to Boston Scientific and a cash position of $36.4 million plus $8 million in escrow. The company submitted a 510(k) for the base biologic matrix...
The HIMSS conference, a cornerstone for health‑tech networking, is increasingly viewed as an inefficient sales funnel. In 2024, roughly 28,000 attendees generated only about 40 qualified conversations per exhibitor, costing $800‑$2,000 per meaningful lead. Advances in large language models and...
The American Society of Nuclear Cardiology (ASNC) announced that the nationwide shortage of technetium‑99m radiotracers used to diagnose transthyretin cardiac amyloidosis is expected to ease by late March. Curium, a key supplier, has already released a PYP lot in mid‑February...
Calgary‑based NanoTess has signed a distribution agreement with diabetes‑care company Embecta to place its NanoSALV Catalytic gel in more than 14,000 Canadian pharmacies. NanoSALV, authorized by Health Canada in 2022, uses micron‑scale catalytic particles to speed cellular reactions, reduce inflammation...
In a First, Researchers Use Stem Cells and Surgery to Treat Spina Bifida in the Womb by @ShellyFan https://t.co/4xO4I0iLJL https://t.co/HV1CGzlMXU
A growing shortage of pediatricians willing to accept Medicaid leaves nearly half of U.S. children in care deserts, especially in urban and suburban areas. Medicaid’s lower reimbursement rates force many practices to operate on razor‑thin margins, prompting closures of pediatric...
The FDA announced a unified adverse‑event database that will eventually incorporate all of its existing reporting systems, including the vaccine‑side‑effect tracker jointly operated with the CDC. The new platform, called the Adverse Event Monitoring System, centralizes data from drugs, biologics,...
/file/attachments/orphans/Op-ed-funding-global-development_415965.jpg)
Traditional aid models are losing traction as funding shrinks and health needs grow, prompting a call for bold, sovereign leadership in global health. The High‑Level Council argues that ambition, not scarcity, should drive system design, emphasizing people‑centred, integrated services. Examples...
