Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
Researchers are expanding CAR‑T cell therapy beyond cancer to treat autoimmune diseases such as lupus and rheumatoid arthritis. Sail Biomedicine’s chief products and operations officer highlighted on the Pharmaceutical Executive podcast that the company has pivoted to RNA‑based CAR‑T platforms, which offer rapid expression and fast repopulation suited for autoimmune modulation. Early results indicate significant therapeutic effects, while the high cost and logistical complexity that hampered oncology applications remain concerns. Competitors originally focused on oncology are similarly redirecting efforts toward non‑cancer indications.
Eli Lilly has issued a public warning after testing revealed a significant impurity formed when tirzepatide is compounded with vitamin B12. The impurity’s health effects are unknown, and the company has alerted the FDA and urged patients to consult physicians....
New York lawmakers rejected Gov. Kathy Hochul's proposal to reform the state's surprise billing arbitration system. The governor's budget aimed to save $56 million by exempting Medicaid and lowering benchmark rates, aligning them with average private insurer payments. The legislature...
Montefiore’s White Plains Hospital Center filed a state plan to construct a 2,320‑square‑foot cardiac extension clinic in Mount Kisco, Westchester. The outpatient facility, slated to cost about $1.8 million and be built in roughly seven months, will provide echocardiography and cardiac...
Durham Police have opened a criminal investigation into alleged failures in breast‑cancer treatment at the County Durham and Darlington NHS Foundation Trust. A 2022 report found unnecessary surgeries, missed cancers and substandard care at the University Hospital of North Durham...
Durham Police have launched a criminal investigation into alleged failures in breast‑cancer treatment at County Durham and Darlington NHS Foundation Trust. A 2022 report identified unnecessary surgeries, missed cancers and substandard care at the University Hospital of North Durham and...
Anthem Blue Cross and Blue Shield, operating as Elevance Health, is extending its "non‑participating care providers" policy to California, marking the 12th state to face a 10% administrative penalty on hospital claims that involve out‑of‑network radiologists. The policy, first rolled...
A BBC questionnaire sent to over 5,000 English GPs received 752 responses about fit‑note refusals for mental‑health claims. While 540 doctors said they have never denied a fit note, 162 admitted to at least one refusal, highlighting tensions around the...
Weight‑loss GLP‑1 drugs such as Wegovy and Zepbound are celebrated for delivering 15‑21% average weight loss, yet roughly one in ten patients are “non‑responders,” shedding less than 5% of body weight. The article follows Jessica Layeux, a cybersecurity professional who...
Republican leaders are uneasy as Health Secretary Robert F. Kennedy Jr. pushes an aggressive anti‑vaccine and pesticide‑reduction agenda under the Make America Healthy Again (MAHA) banner. While the White House cools on his vaccine stance, Kennedy’s supporters demand stricter COVID‑19 vaccine...
North West London and North Central London Integrated Care Boards have launched a preliminary market engagement to procure an end‑to‑end digital solution for complex care commissioning, with a budget of up to £3.8 million. The platform will replace outdated systems, improve...
George Medicines has signed an exclusive licensing and supply agreement with South Korea’s Ahngook Pharmaceutical to bring its triple‑combination antihypertensive pill, GMRx2, to the Korean market. The single‑pill formulation blends telmisartan, amlodipine and indapamide in three dose strengths, aiming for...
Codoxo has launched Deepfake Detection, an AI‑driven solution that scans medical documentation, diagnostic images and claim context in seconds to flag synthetic or manipulated records. The tool embeds explainable risk scores into payer fraud‑prevention workflows, enabling health plans to intercept...
International Workplace Group (IWG) has introduced Humanly, a flexible workspace concept tailored for healthcare and wellbeing practitioners in the United Kingdom. The inaugural 7,700‑sq‑ft site at Dockside Chatham Maritime offers private consultation suites, treatment rooms and gym studios on short‑term,...
Philips reaffirmed its commitment to expand equitable, high‑quality healthcare in Indonesia, citing the country’s 98% universal health coverage and rising non‑communicable disease burden. The company highlighted its Strengthening Indonesia’s Healthcare Referral Network (SIHREN) program, which will extend image‑guided therapy and...
ADHD affects roughly 7 million children in the United States—about 11.4% of the 3‑17‑year‑old population—and prevalence has risen by a million since 2016. Nearly 30% of diagnosed children receive no medication or behavioral therapy, and formal assessment remains uneven across geography,...
The cross‑sectional study of 902 adult survivors of the 2023 Herat earthquake found substantial deficits in health‑related quality of life (HRQoL). Approximately 38% reported low physical HRQoL and 37% low psychological HRQoL, with women, widowed/divorced persons, large households, low‑income and...
Corneal Allogenic Intracorneal Ring Segments (CAIRS) have been used to improve vision in keratoconus and post‑LASIK ectasia, but a multicenter case series of nine eyes reveals notable complications. Patients experienced progressive corneal neovascularization, lipoid keratopathy, and segment extrusion, linked to...
A retrospective case‑control study at St. Paul Hospital Millennium Medical College identified six key determinants of neonatal mortality among 324 NICU admissions from 2020‑2022. Lack of antenatal care (ANC) visits, home delivery, pregnancy‑induced hypertension, low birth weight, prematurity, and fetal...
A cross‑sectional study of 238 gastrointestinal cancer patients used symptom‑level network analysis to map the frailty‑depression relationship. The strongest links were found between slowed gait and low physical activity, and between bradykinesia/agitation with suicidal ideation and guilt. PHQ‑4 (lack of...
Researchers at Haji Adam Malik General Hospital examined 69 acute ischemic stroke patients to determine whether admission D‑dimer and fibrinogen levels reflect stroke severity. Patients with severe strokes had median D‑dimer levels of 2060 ng/mL versus 620 ng/mL in moderate cases, and...
C2N Diagnostics has signed a partnership with BeauBrain Healthcare to introduce its PrecivityAD2 blood test for Alzheimer’s disease in South Korea, targeting patients aged 50 and older with mild cognitive impairment or dementia. Clinical studies published in JAMA and npj...
Researchers have created a New Zealand rabbit model that mimics biliary stenting by using a transduodenal wall puncture and a modified intravenous catheter. The experimental group achieved an 86.7% technical success rate, with most complications being mild and transient. Serum liver...
A retrospective cohort of 169 critically ill patients receiving tigecycline showed significant reductions in blood glucose at three daily time points. Hypoglycemia occurred in 11.2% of patients and was linked to a nearly four‑fold increase in 28‑day mortality (OR 3.83). Larger...
A cross‑sectional study of 495 ureteroscopic lithotripsy cases identified stone length and maximum stone density as independent risk factors that extend operative time, while simple ureteral stones reduce it. Using LASSO selection, researchers built a Gamma regression model and a...
A 12‑year‑old girl presented with recurrent fever of unknown origin, later developing intermittent joint pain. Extensive infectious, rheumatologic and oncologic testing, including cultures, metagenomic sequencing and bone‑marrow analysis, were negative. MRI and PET‑CT revealed multifocal hypermetabolic bone lesions, prompting concern...
Los Angeles County now hosts more than 3,000 life‑science companies, outpacing peer regions, and generated roughly $58 billion in annual economic output. Venture‑capital inflows surged to $4.4 billion in 2024, a 119 % jump, underscoring growing investor confidence. The ecosystem benefits from a...
The Unilab Center for Health Policy (UCHP) and Naga City signed a Memorandum of Understanding to launch a collaborative research and implementation agenda aimed at strengthening primary health care. The partnership will develop digital tools, conduct a comprehensive health system...
From skin checking applications and AI to remote care devices and robotics, the field is going through a paradigm shift making patients more and more the point of care. Smart algorithms will soon diagnose skin cancer, dermatologists consult patients online, and...
Cairn Surgical has filed a De Novo 510(k) application with the U.S. FDA for its Breast Cancer Locator (BCL) System, a device designed to improve the accuracy of breast‑conserving surgery. The company completed a pivotal U.S. trial that demonstrated a...
The UK government has negotiated a UK‑US pharmaceutical trade deal that raises NICE’s cost‑effectiveness threshold from £20‑30k to £25‑35k per QALY. The higher threshold will deem more expensive drugs cost‑effective, increasing NHS drug spend while reducing rebate rates from 22.9%...
The UK National Health Service faces widening health inequities driven by ageing demographics, workforce shortages, and funding gaps, especially in deprived regions. A digital‑first community care model—leveraging remote patient monitoring, telehealth, AI‑driven personalization, and integrated data analytics—offers a pathway to...
U.S. servicemembers are experiencing a sharp increase in mental‑health diagnoses, with a 17% rise between 2022 and 2023. Only 13% of clinicians possess sufficient cultural competence to treat veteran populations, and merely 31.7% of affected personnel receive any care, while...
Cigna Healthcare Hong Kong has launched the VitalGuard Critical Illness Plan, adding a lump‑sum protection product to its medical insurance suite. The plan offers up to HK$4 million coverage for 110 diseases, including 58 critical illnesses, with a 5‑year renewable term...
Wiley is licensing its extensive portfolio of peer‑reviewed medical content to OpenEvidence, the clinical AI platform used by more than 40% of U.S. physicians. The deal brings the Cochrane Database of Systematic Reviews, Cochrane Clinical Answers, and over 400 Wiley...
Breast cancer treatments, especially chemotherapy and endocrine therapy, often induce menopause or exacerbate menopausal symptoms such as hot flashes, vaginal dryness, and bone loss. These symptoms can be temporary or permanent, depending on age, treatment type, and ovarian reserve. Nonhormonal...
Breast cancer survivors face heightened cardiovascular risk, as radiation, certain chemotherapies, HER2‑targeted drugs, and hormone treatments can impair heart function. Advances in imaging and cardiac‑sparing radiation techniques allow clinicians to detect and mitigate damage early. Oncologists now coordinate with cardiologists...
A new West Health‑Gallup poll reveals that one‑third of Americans – about 82 million people – are cutting everyday expenses or borrowing money to afford health‑care. Health‑care costs now rank above food, gas and utilities as the nation’s top economic worry....
Medical‑technology giant Stryker disclosed an Iran‑linked cyberattack that compromised its Microsoft Intune mobile device management (MDM) platform, forcing remote wipes of thousands of laptops and smartphones worldwide. The breach, claimed by the Handala collective, showed no ransomware but highlighted the...
The Global Map of Medical Drone Projects And Trials We analyzed the state of medical drones worldwide. To achieve that, we had to dive into the global literature and announcements to find all of these exciting projects that involved the use...
Find out more about kidney health and how to support underprivileged kidney patients at https://www.kdf.org.sg (link in bio) #worldkidneyday #worldkidneyday2026
The FDA has opened a public docket to solicit comments on its long‑standing Scale‑Up and Post‑Approval Changes (SUPAC) guidances for immediate‑release solid oral, non‑sterile semisolid, modified‑release solid oral dosage forms and the manufacturing equipment addendum. The agency seeks feedback on...
If you are curious about seeing what may be the last competent FDA advisory committee left standing in action as they contribute to determining access to flu shots next fall, join me, @jessicamalaty, & @SaveAmericaMvm at 12:30 pm ET on...
Interaction #Analytics Topic #AI Delivers Faster, Smarter Analysis with #GenerativeAI. Visit Booth 4843 to see #AI-first #CX in action. @NICELtd #HIMSS26 #HIMSS2026 https://t.co/2Ji4nhmAmx
The Australian government is considering legislation to ban infant‑formula advertising as the voluntary marketing agreement expires in February 2025. Recent analysis identified 158 online ads that use health‑boosting claims to tap parental anxiety, despite breastfeeding rates falling to only 37 percent by...
NiCE is defining the next standard of care... with data that moves as fast as the patient. Visit Booth 4843 to see #AI-first #CX in action. @NICELtd #HIMSS26 #HIMSS2026 https://t.co/3ffKU5tupi
Gut Microbiota Manipulation by Probiotic Lacticaseibacillus paracasei DG I1572 as New Therapeutical Strategy to Counteract Vascular Inflammaging https://t.co/91dumlTNgU https://t.co/tkL0m8P6nd
Cancer deaths in the U.S. peaked around 1990. After adjusting for aging of the population, mortality has fallen by about 35% since then. The biggest drivers: • Smoking declined dramatically • Screening improved • Treatments got better A massive and often overlooked public health success. https://t.co/Ev7pSnunoY
Here’s my take on what HHS and the White House got wrong about autism in 2025-2026 and how they could turn this around and do something innovative and helpful https://t.co/pxLaDLInlf
Wish you could hear everything around you, whether you're at a noisy restaurant or just watching TV at home? I check out the Cearvol Nano OTC Hearing Aids in various locations and find it's a great way to turn up...
