Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
AstraZeneca has partnered with actor Joshua Jackson and the Philadelphia Flyers mascot Gritty for the Get Body Checked Against Cancer campaign. The initiative leverages hockey’s "body check" metaphor to urge fans to discuss cancer‑screening options with their doctors. AstraZeneca highlighted that 65% of Americans are behind on recommended screenings and noted rising cancer rates among those under 50. To date the company has contributed $1.1 million to the NHL‑backed Hockey Fights Cancer program.
RFK Jr is trying to get 14 peptides, without data on safety or efficacy, licensed and approved by FDA. His favorite is BPC-157. "Only three small human studies of BPC-157 exist, for instance, the largest of which is a telephone...
Safety‑net health providers are bracing for massive Medicaid cuts enacted by the recent "Big Beautiful Bill," which will strip billions from state programs and impose strict work‑requirement reporting. At the 2026 HIMSS conference, experts warned that these changes could trigger...
Heru unveiled PretestPro™ at Vision Expo, a VR‑powered diagnostic headset that completes four essential eye‑pre‑tests in under two minutes. The wearable platform merges visual field, near cover test, extraocular motility and quantitative pupillometry into a single, AI‑guided workflow, replacing multiple...
Alkermes plc announced the inaugural Alkermes Pathways APN Research Awards™, a competitive grant program offering up to $10,000 per project to licensed psychiatric‑mental health nurse practitioners researching schizophrenia or bipolar I disorder. The application window runs from March 16 to...
Baseimmune announced a new fibrosis‑focused pipeline leveraging its computational protein design platform to create multi‑pathway immunotherapies, starting with idiopathic pulmonary fibrosis (IPF). The company aims to deliver proof‑of‑concept efficacy data for its lead IPF program in 2026‑2027, addressing the limitations...
Rhode Island Senate Bill 2774, introduced on March 4, would prohibit the sale of over‑the‑counter diet pills and weight‑loss or muscle‑building supplements to anyone under 18. The bill requires retailers to store these products in locked cases or behind counters, limiting...
A meta‑analysis of six randomized trials involving 5,924 stable CAD patients with atrial fibrillation found that oral anticoagulant (OAC) monotherapy reduced cardiovascular mortality by 31% and major bleeding by 54% compared with OAC plus a single antiplatelet. The benefit persisted...
Recent advances in collective intelligence and artificial intelligence are enabling large‑scale, data‑driven collaboration among clinicians. Studies show that pooling independent physician judgments can lift diagnostic accuracy from roughly 46% to 76%, and hybrid human‑AI constellations outperform either humans or models...
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Snakebite envenoming kills over 125,000 people each year and leaves three times as many disabled, while current horse‑derived antivenoms trigger severe allergic reactions in nearly half of patients. The high cost—up to $100,000 per course—and limited hospital access leave rural...
On March 12, 2026, TCTMD’s Heart Valve Matters podcast featured Ami Bhatt and John Carney discussing the role of in‑vivo assessments in shaping next‑generation cardiac valve prostheses for children with congenital heart disease. The hosts highlighted how animal studies and...
BridgeBio Pharma reported that its small‑molecule candidate BBP‑418 produced a 1.8‑fold increase in the α‑dystroglycan biomarker in a Phase 3 FORTIFY trial for limb‑girdle muscular dystrophy type 2I/R9, with effects sustained through 12 months. The trial enrolled 81 patients and also showed...
Stephanie Mojica lost 218 pounds after a duodenal‑switch bariatric surgery performed in Mexico, but severe post‑operative dehydration and nutrient deficiencies left her with permanent mobility loss and vision problems. She now relies on a walker and wheelchair, despite having shed the weight...
Innovaccer announced its Gravity platform has earned Built on Validated Partner status with Databricks, confirming production use of the lakehouse stack. The partnership integrates Delta Lake, Databricks SQL, and Managed MLflow into Gravity’s AI infrastructure, streamlining data transformation and model...
The CMS Advancing Interoperability and Improving Prior Authorization Final Rule requires all health‑care entities to deploy specific prior‑auth APIs by January 1, 2027. A February 2026 WEDI survey shows payers have largely caught up, with only 10% still idle, down from 43% a...
Lantern appointed Greg Chisholm as CFO, leveraging experience from HelloFresh, Wayfair, and McKinsey. He is focused on mapping the health‑care business’s complexity and shaping capital‑allocation decisions as the company scales at roughly 50% annual growth. Chisholm points to structural cost...
dxw conducted a two‑week design sprint with NHS England to overhaul reporting for breast‑screening image readers. The team mapped the end‑to‑end workflow, built a unified data model, and defined key performance indicators for readers, unit directors, and the Screening Quality...
The AMA’s 2026 Physician Survey shows AI adoption has more than doubled, with 81% of doctors now using AI tools versus 38% in 2023. Physicians average 2.3 AI use cases, driven by clinical documentation and research summarization. Seventy percent view...
Aplagon Therapeutics has administered the first dose of its intravenous APAC candidate to a patient in a Phase 2a (HEALING) trial for peripheral arterial occlusive disease leading to chronic limb‑threatening ischemia in Finland. The study will enroll approximately 42 CLTI...
A very important prospective (!) study from Google and Beth Israel Deaconess Medical Center about using AI before a new ambulatory primary care visit. The patient talks with a conversational AI that will summarize every important detail for the physician by...
The Recruitment and Employment Confederation (REC) is urging the NHS to add agency workers to its annual Staff Survey, highlighting a critical blind spot that excludes a sizable portion of the workforce. While the survey recently expanded to include Bank‑only...
Jacobs and colleagues present a state‑of‑the‑art review of psilocybin and MDMA‑assisted therapies, highlighting their potential for treatment‑resistant depression and PTSD. The authors emphasize the distinct, session‑based paradigm that leverages acute neurobiological changes to produce lasting clinical benefits. However, they also...
A new American Cancer Society analysis shows colorectal cancer has become the leading cause of cancer death for Americans under 50, overtaking all other malignancies. Roughly three‑quarters of these young patients are diagnosed at an advanced stage because routine colonoscopies...
Tri‑City Cardiology, a Phoenix‑based physician group, and three doctors agreed to pay $4.75 million to settle False Claims Act allegations that they performed medically unnecessary vein ablations between 2017 and 2022. The government alleges the physicians falsified vein measurements, symptom documentation,...
The FDA issued draft guidance that could lower biosimilar testing requirements by permitting foreign comparator data, potentially cutting development costs by about half. Over 80 biosimilars have been approved in the U.S. since the first approval 11 years ago, yet...
An American physician underwent a full “Ningen Dock” preventive checkup at a Tokyo hospital, completing more than 20 tests in just four hours. The $1,800 exam delivered immediate lab results and a physician consultation, contrasting sharply with the fragmented, often...
MedicBite Clinic Madeira opened in Funchal as Europe’s first multidisciplinary facility dedicated to structural alignment medicine, emphasizing the link between posture and longevity. Backed by over €11.5 million in investment and the Guinness‑record‑holding Coolzoone brand, the clinic combines digital‑navigated therapies targeting...
Roche announced a three‑fold expansion of its footprint at Harvard University’s Enterprise Research Campus, increasing space from 30,000 to 100,000 square feet. The move is part of a broader $50 billion U.S. R&D investment plan that aims to add more than...
A recent AHIP survey shows nearly nine in ten U.S. workers are satisfied with their employer‑provided health insurance, citing financial security and peace of mind. Health coverage ranks as the top workplace benefit, with 68% naming it most valuable, and...
Insulet presented data from its EVOLUTION 2C feasibility study of a fully closed‑loop (FCL) automated insulin delivery system for adults with type 2 diabetes at ATTD'26. In the 24‑patient trial, the final algorithm raised time‑in‑range (TIR) to an average 68%,...
Bavarian Nordic has signed a manufacturing agreement with the Serum Institute of India to transfer full technology for its chikungunya vaccine, CHIKV VLP (branded Vimkunya). The deal replaces an earlier partnership with Biological E and builds on the companies' existing mpox‑vaccine collaboration....
The HHS Office of Inspector General’s July 2025 report found that hospitals failed to capture 49% of patient‑harm events among Medicare inpatients, a modest improvement from the 86% miss rate reported in 2012. Staff most often dismissed events as expected complications...
UnitedHealth used its Barclays Healthcare Forum to lay out a cautious 2026 outlook anchored by a 10% Medicare cost trend and modest Medicaid rate gains, while flagging that 2027 should see the payoff from AI‑driven efficiency and OptumHealth margin recovery....
GAO reports that federal HHS grant programs allocated $103.2 million from 2022‑2024 to improve mental health among the 17 million‑strong health‑care workforce. Studies show 34% of workers experienced depression and 57% anxiety in 2022, while burnout rose to 46% from 32% in...
The UK government has set an interim NHS waiting‑time goal that by the end of March 2026 at least 65 % of patients should wait no longer than 18 weeks for elective treatment. To meet this, each English NHS trust must either achieve...
The UK government has set a new interim target for England’s NHS to have at least 65 % of patients receive planned treatment within 18 weeks by the end of March 2026. Each NHS trust must either reach a 60 % compliance rate or...
Anthony Guerra, founder of healthsystemCIO, shares his personal productivity system built around Apple Reminders. He structures a master "Work" list with sub‑lists, sections, and date‑based items that he drags and updates throughout the day. The core insight is that effective prioritization—not...
Night‑shift physicians experience circadian misalignment that raises fatigue, metabolic and cardiovascular risk. Dr. Oraedu presents evidence‑based tactics—steady sleep windows, strategic light exposure, timed nutrition, caffeine timing, brief exercise, health monitoring, and wind‑down rituals—to counteract these effects. Applying these habits can...
GLP‑1 drugs such as semaglutide have surged from diabetes treatment to a mass‑market weight‑loss solution, with roughly 12.4% of Americans now using them. Global sales are projected to climb from $50‑60 billion today to over $135 billion within a decade, driven largely...
The FDA unveiled the Adverse Event Monitoring System (AEMS), a unified platform that shifts drug safety surveillance from quarterly updates to real‑time reporting and is expected to save roughly $120 million over five years. Simultaneously, a direct‑to‑employer drug‑purchasing model is gaining...
Suicide is now the LEADING cause of death for US medical residents. We are losing 500 physicians a year. That is an entire med school class. Stop demanding "resilience" from doctors and start fixing the system. Tie executive bonuses to wellness, not...
Yup, as Dr Bernie says, public health is not a zero-sum game, need a focus on women's AND men's health/ Momentum builds for a federal office of men’s health focused on disease prevention https://t.co/ONPLMEzKWv via @statnews https://t.co/ASKuoMrJSO
Eli Lilly warned that compounded versions of its GLP‑1 drugs Mounjaro and Zepbound, when mixed with vitamin B12, may contain unsafe impurities. The alert follows growing off‑label compounding as demand outpaces supply. Lilly’s notice urges clinicians and patients to verify product sources...
Such a dismal conclusion. Taking on debt, skipping meals, delaying retirement, etc, etc, in order to cover healthcare costs. When does America come to grips with healthcare costs? Something has to give. https://t.co/L48u4W2CDG
In January there was ChatGPT Health, Claude Health. Today there's Microsoft CoPilot Health. And more to come in the genAI -> health landscape https://t.co/TInH9YTvwA
The FDA announced that a single pivotal trial can now satisfy efficacy requirements for new drug applications, replacing the previous two‑study mandate. This change raises expectations for data depth, quality, and risk‑based management throughout the trial lifecycle. Guests Oxana Iliach...
Pierre Fabre and $ATRA said FDA meeting to discuss the Ebvallo CRL has been scheduled. (Likely occuring within the next month.)
The FDA is targeting telehealth marketing of GLP-1 drugs. Who’s prescribing them? Medical groups face ‘tricky’ questions when partners make misleading claims via @KatieMPalmer https://t.co/pf4Fwa7W7r
Olympus has introduced the VISERA ELITE III surgical imaging platform in the United States, the third joint offering from the Sony‑Olympus Medical partnership. The system combines continuous auto‑focus, true 4K, 3D, narrow‑band and fluorescence (IR/ICG) imaging in a single software‑driven unit that...
The Whiteboard Windfall: A Lesson in NHS Negotiations by @Timothy_Hughes https://t.co/dOWFQNFRXU @DLAIgnite #SocialSelling #DigitalSelling #Sales #SalesTips #SalesLeader #Salesforce #SalesEnablement #RevOps #Leadership #Marketing #SalesNegotiation https://t.co/sWTVEyWdht
