
AstraZeneca’s Alexion unit intends to file a new long‑acting enzyme replacement therapy, efzimfotase alfa, as a successor to its Strensiq (asfotase alfa) for hypophosphatasia (HPP). Phase 3 data showed the drug met primary endpoints in pediatric patients but failed to achieve a significant improvement in the six‑minute walk test for adolescents and adults, though fatigue scores improved. Strensiq generated $1.68 billion in sales last year and faces patent expiry by the early 2030s, prompting AZ to seek a biweekly formulation that could simplify dosing. Competitors such as AM Pharma are also advancing alternative ERTs, intensifying market pressure.
Velindre University NHS Trust has chosen Noveva Software Group’s CCube Cloud to power the electronic document management system for Wales’ new flagship cancer centre, slated to open in spring 2027. The cloud‑based platform will replace on‑site paper storage, integrating with...

India’s Union Budget raised the health ministry’s allocation by 10% to over Rs 1.06 lakh crore—approximately $13 billion—signalling a major fiscal push for the sector. The plan earmarks training for 100,000 allied‑health professionals and 150,000 caregivers over the next five years. Funding will also...
The NHS Digital Maturity Assessment 2025 released scores for 47 digital domains, revealing the lowest‑performing trusts. Torbay and South Devon NHS Foundation Trusts (acute and community) sit at the bottom with a 1.5 rating, a slight rise from 1.4 in...
Blackstone announced the closing of its newest life sciences fund at $6.3 billion, topping the original target. The vehicle will back biotech, pharmaceutical and medical‑technology companies from seed to growth stages. Investor enthusiasm for health‑tech has surged since the pandemic, allowing...
Luscii’s flexible digital platform now underpins Maidstone and Tunbridge Wells NHS Trust’s acute virtual ward, enabling remote monitoring across more than 150 conditions. Matron Fay Johnstone’s team has cared for over 4,000 patients at home, delivering hospital‑level care while freeing...

In August, the Trump administration ordered states to re‑verify Medicaid enrollment for individuals whose immigration status was unclear. Five states that reported back found only a handful of undocumented enrollees were removed, with Pennsylvania and Colorado terminating none, Texas 77,...
The State Department has transferred only about $640 million of the $4.6 billion PEPFAR budget to the CDC, leaving a roughly $660 million shortfall for the fiscal year. The Trump administration’s shift from USAID to a CDC‑led model and its new memorandum‑of‑understanding (MOU)...
uBriGene Biosciences has entered a strategic partnership with Cellinfinity BIO to accelerate the development of in‑vivo CAR‑T therapies for both solid tumors and hematologic cancers. The collaboration will apply uBriGene’s LVV Turbo platform, which delivers up to 80% purification recovery...
uBriGene Biosciences has entered a strategic partnership with Cellinfinity BIO to fast‑track in‑vivo CAR‑T programs for both solid and hematologic cancers. The deal leverages uBriGene’s LVV Turbo platform, which delivers GMP‑grade lentiviral vectors with up to 80% purification recovery and...
At the 2026 ACC Scientific Session, Brazilian investigators presented a meta‑analysis of three placebo‑controlled trials (1,060 patients) evaluating lorundrostat in uncontrolled hypertension. Lorundrostat 50 mg reduced systolic blood pressure by 9.08 mm Hg and diastolic by 3.48 mm Hg, while the 100 mg dose achieved an...
A systematic review and meta‑analysis of 15 randomized trials involving 644 patients and 742 implants examined low‑level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT) as adjuncts to non‑surgical debridement for peri‑implantitis. The analysis found modest but statistically significant reductions...
A pre‑print study compared capillary dried blood spot (DBS) microsampling—including filter‑paper punches and Mitra volumetric absorptive microsamplers—with venous plasma for multiplex serosurveillance of seven vaccine‑preventable diseases. The analysis showed strong agreement for six pathogens, with ≥93% of paired measurements within...

The Philippine Health Insurance Corporation (PhilHealth) will launch a Statement of Premium Account (SPA) Generator on April 1 for self‑paying members. Under the new “No SPA, No Payment” rule, members must create a QR‑coded SPA before any contribution can be processed....

Imaging interpretation turnaround times more than doubled between 2014 and 2023, climbing from roughly 2 hours 11 minutes to 4 hours 37 minutes – a 113% increase. The study of 2.6 million Medicare imaging claims shows the steepest jumps in CT (318%) and MR (256%) scans. A...

Merck presented Phase III CORALreef AddOn trial results for enlicitide decanoate, an oral PCSK9 inhibitor, in hypercholesterolemic adults on statins. At eight weeks, the drug lowered LDL‑C by 64.6%, outperforming bempedoic acid, ezetimibe and their combination. It also achieved 54.6%...
Humber Teaching NHS Foundation Trust has secured NHS England funding to spearhead the rollout of appointment‑management functionality within the NHS App, a capability that will be extended to 11 other trusts using the SystmOne electronic patient record system. The new...

Mitchell H. Katz, CEO of NYC Health + Hospitals, announced the system is prepared to let artificial‑intelligence algorithms perform first‑read radiology interpretations once state regulations allow. He highlighted AI’s growing role in mammogram and X‑ray analysis and the potential for...

Singapore’s Communicable Diseases Agency will implement enhanced precautionary measures against measles starting 1 April 2026. The policy follows detection of three genetically linked cases in January and 12 additional cases through March, most of whom were unvaccinated. Measures include mandatory testing for...

A new Gallup poll released March 31 shows healthcare is the top domestic worry for 61% of Americans, reclaiming the lead from the economy. Overall anxiety about the 16 surveyed issues fell to an average 43%, the lowest level since early 2020,...

BayCare, a west‑central Florida hospital system, is allocating roughly $22.5 million to centralize and expand interventional radiology (IR) services at St. Anthony’s Hospital in St. Petersburg. The investment will fund two new bi‑plane suites, 12 pre‑ and post‑procedure bays, and dedicated patient waiting...

Hong Kong's mental health indicators have reached a critical red‑light level, with depression and anxiety scores climbing to 7.27 and 5.9, the highest since 2012. A recent survey shows 55 % of residents hesitate to seek professional help, while AI assistants...

Teva Pharmaceutical received U.S. FDA approval for Ponlimsi, a biosimilar to Amgen’s Prolia (denosumab), covering all approved indications. The approval was granted after extensive analytical and clinical studies demonstrated comparable efficacy, safety, and immunogenicity to the reference product. In parallel,...
Adult orthodontic treatment is increasingly common as modern technologies like clear aligners and ceramic braces make discreet, effective tooth movement possible well beyond adolescence. While teeth can shift at any age, successful outcomes hinge on healthy gums, adequate bone density,...
Choosing Invisalign is only half the journey; selecting a qualified provider determines treatment success. In Thornton, providers differ in experience, digital planning, communication, and post‑treatment support. The article outlines criteria such as case volume, use of intraoral scanners, clear timeline...

Medical technology is transforming how clinicians diagnose binocular vision disorders, which often hide behind generic eye‑strain complaints. Traditional eye exams focus on static acuity, missing dynamic issues like accommodative and vergence dysfunction that cause headaches, dizziness, and reading difficulty. New...

Dr. Nishi Patel outlines how echocardiography and cardiac MRI together shape modern cardiology in the United States. Echocardiograms serve as a low‑cost, widely available first‑line tool that provides real‑time functional data, while cardiac MRI delivers high‑resolution tissue characterization for complex...
Researchers have engineered a bioinspired nanoparticle that co‑assembles an anti‑VEGF peptide with copper ions, adds a ROS‑scavenging moiety and a cell‑penetrating peptide, and achieves deep corneal delivery. The formulation extends ocular residence to roughly 70 minutes and reaches 300 µm in a...
Researchers have fabricated a large‑scale ferroelectric ceramic wafer (PNN‑PZT) using solid‑state sintering, achieving record‑high sensitivity for self‑powered X‑ray detection. At 150 °C the detector reaches 248 µC Gy⁻¹ cm⁻² sensitivity and a detection limit of 6.76 nGy s⁻¹, surpassing commercial amorphous selenium devices. The material exhibits...
A 2026 Frontiers in Nutrition study of 250 kidney‑transplant recipients found that pre‑operative visceral adipose tissue (VAT) measured by CT strongly predicts post‑transplant dyslipidemia. While BMI and other fat depots correlated with lipid abnormalities in univariate tests, multivariate models identified...
Researchers analyzed over 158,000 adults aged 50+ with vision or hearing impairment using the TriNetX database. After propensity‑score matching, those with vitamin D deficiency (<20 ng/mL) faced a 55 % higher hazard of developing dementia over ten years compared with individuals with...
Researchers applied the ACE Star evidence‑based model to create a standardized enteral nutrition protocol for neurocritical care patients in a Chinese tertiary ICU. Compared with a historical control, the protocol lowered feeding intolerance incidence from 70% to 31% and boosted...
A new review in *Metabolism* outlines how L‑carnitine may counteract metabolic dysfunction‑associated steatotic liver disease (MASLD), which now afflicts roughly one‑third of the global population. The authors detail L‑carnitine’s role in boosting mitochondrial fatty‑acid oxidation, improving insulin sensitivity, and dampening...

A BBC investigation found that two British families who underwent IVF at Dogus IVF Centre in northern Cyprus received sperm from different, undisclosed donors, meaning their children are not biologically related. DNA testing confirmed neither child was conceived with the...

Home Halo, a non‑medical home‑care provider, is entering franchising with a goal of opening 10‑15 locations in the next year and scaling to 20‑30 new sites annually thereafter. The company’s first franchisee controls twelve territories in eastern Massachusetts, using a...
Colorectal cancer diagnoses are rising among adults under 50, prompting a shift in screening recommendations. The U.S. Preventive Services Task Force now advises average‑risk individuals to begin colonoscopy screening at age 45, down from 50. High‑risk patients—those with symptoms, family...

The UK’s statutory sick pay (SSP) remains at £118.75 a week (about $150), one of the lowest among advanced economies. Despite new legislation eliminating the three‑day unpaid waiting period and extending coverage to part‑time and low‑wage workers, the rate has...
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Paxil (paroxetine), a short‑acting SSRI, often triggers withdrawal symptoms within two to three days of dose reduction, with effects lasting up to six weeks or longer. Over half of antidepressant discontinuers report such symptoms, including nausea, dizziness, vivid dreams, anxiety,...

Pancreatic cancer’s five‑year survival sits at just 13%, making early, expert care essential. The University of Michigan Rogel and Blondy Center emphasizes a multidisciplinary, high‑volume approach that includes surgeons, oncologists, dietitians, and palliative specialists. Patients are urged to seek centers...

The U.S. Air Force School of Aerospace Medicine’s Missile Community Cancer Study, now analyzing 148,078 cases from 1976‑2010, found statistically higher rates of testicular cancer and Hodgkin lymphoma among intercontinental ballistic missile (ICBM) personnel compared with other Airmen. Earlier phases...

A large cluster‑randomized trial of more than 21,000 acute ischemic‑stroke patients across 77 Chinese hospitals tested an AI‑powered clinical decision support system (CDSS). The tool, which combines AI‑assisted imaging with guideline‑based treatment prompts, lowered the 3‑month composite vascular‑event rate from...

The National Institutes of Health announced 15 winning teams in its Nutrition for Our Immune System Health (NOURISH) Autoimmunity Challenge, each receiving a $10,000 prize. The challenge solicited scalable, patient‑centered ideas that integrate diet, microbiome, and multi‑omics approaches to study...
Cheshire Independent Living Services in London, Ontario has rolled out GoldCare’s integrated healthcare software, including a consumer portal that offers real‑time access to personal attendant schedules. The portal empowers consumers and families with direct visibility, enhancing autonomy and reducing reliance...
On March 31 2026 the Canadian Institute for Health Information released Version 2 of the Canadian Core Data for Interoperability (CACDI), a national standard that defines core patient, clinical, and provider data for seamless exchange. Co‑designed with patients, clinicians, Indigenous groups and digital‑health...
Royal Victoria Regional Health Centre in Barrie completed a one‑year pilot of Hypercare for its Vascular Life and Limb emergency pathway. The platform replaced individual phone calls with a single‑tap, secure group alert, cutting hospital acceptance time from 15 minutes...
Medly, a smartphone‑based remote monitoring system for heart‑failure patients developed by Toronto’s University Health Network, is now being commercialized by Vitall Intelligence. The platform gathers weight, blood pressure and heart‑rate data via Bluetooth devices and uses an algorithm to flag...

The FDA has warned consumers to avoid Boner Bears Honey, a sexual‑enhancement honey sold online and in some stores, after laboratory tests revealed it contains undeclared sildenafil and tadalafil. The product was identified during an inspection of Pure Vitamins and...
Neurosurgeons at Toronto’s St. Michael’s Hospital have begun using the Hyperfine Swoop® low‑field MRI scanner inside the operating room to obtain immediate post‑resection images. The portable 0.064‑tesla device can be wheeled into the suite, allowing scans within minutes while surgeons...
The University of Ottawa has inaugurated the Ottawa Medical Artificial Intelligence Research Institute (OMARI), an applied‑research hub embedded in its Faculty of Medicine and linked to the city’s six hospitals. Led by AI expert Dr. Khaled El Emam, OMARI aims to...
MiNK Therapeutics reported a cash position of $14.3 million, extended through 2026 after a $1.2 million raise, while posting a $2.9 million net loss for Q4. Clinical data showed AGENT‑797 combined with PD‑1 achieved a median overall survival of roughly 23 months in heavily...