A recent preclinical study identified BIRC5 and MCL‑1 as co‑drivers of survival in mantle cell lymphoma (MCL) and demonstrated that simultaneous inhibition with YM155 and S63845 produces strong synergistic killing of cancer cells. The combination was effective across both treatment‑naïve and ibrutinib‑resistant MCL models, markedly increasing apoptosis via mitochondrial dysfunction and reducing cancer stem‑like cell markers. Adding the dual‑inhibition regimen to standard agents such as ibrutinib or bortezomib allowed substantial dose reductions while preserving efficacy. Researchers propose clinical trials to validate safety and therapeutic benefit in patients.
Intermountain Children’s Health and its Primary Children’s Hospital have become members of a national trauma and grief network led by the Meadows Mental Health Policy Institute. The network, which also includes hospitals in Michigan, Louisiana and Texas, aims to standardize...
A multicenter study published in the Journal of the American Heart Association introduced a machine‑learning model that predicts five‑year heart‑failure risk in chronic kidney disease patients with higher accuracy than existing tools. Using routine clinical data, the XGBoost algorithm achieved...

On March 20, 2026 the Federal Trade Commission announced a new Healthcare Task Force that unites antitrust and consumer‑protection resources to curb consolidation‑driven price hikes and quality gaps. The task force will be co‑chaired by leaders from the FTC’s Competition...
Grady Health System announced that President and CEO John Haupert will retire at the end of 2026 after a 35‑year healthcare career, with COO Anthony Saul slated to assume the role on Jan. 1, 2027. The transition coincides with a $1 billion...
A recent Frontiers in Digital Health study examined wearable technology adoption among 64 multiple sclerosis (MS) patients. Although intention to use wearables was comparable to patients with other chronic conditions, only 34% of MS patients wore devices regularly, with 34%...
Sannah Kahal has been appointed vice president of finance at Children’s Minnesota, a Minneapolis‑based health system, effective immediately. The announcement, posted on LinkedIn on March 31, highlights her responsibility for capital planning, controllership, enterprise reporting, financial planning and analysis, decision support,...
Researchers at Penn Vet used lipid nanoparticles (LNPs) to deliver FAP‑CAR mRNA directly to patients' T cells, enabling in‑vivo engineering of CAR T cells that attack cancer‑associated fibroblasts in pancreatic ductal adenocarcinoma. In a preclinical mouse model, a single dose of...
A retrospective cohort of 118,740 Israeli adults found that serum IgE levels below 25 IU/mL were associated with almost double the hazard of developing chronic lymphocytic leukemia (CLL) over a seven‑year follow‑up. The multivariable Cox model adjusted for age, sex, obesity,...

Researchers at Tongji Hospital in Wuhan built a closed‑loop digital intelligence platform that integrates scheduling and report dispatch into the electronic health record. Post‑implementation, exam volume rose 66.4% while CT appointment times fell 72.4% and MRI times dropped 33.8%. However,...
Soficabtagene geleucel (WU‑CART‑007), an off‑the‑shelf CRISPR‑engineered CAR‑T therapy, received FDA Breakthrough Therapy Designation for relapsed or refractory T‑cell leukemia and lymphoma. In a phase 1/2 trial of 28 patients, the drug achieved a 91% overall response rate and a 73% complete...

New data from the PRO‑TAVI trial, presented at ACC.26 and published in The Lancet, show that deferring percutaneous coronary intervention (PCI) in elderly patients undergoing transcatheter aortic valve replacement (TAVR) yields outcomes comparable to performing PCI beforehand. The trial enrolled...

A newly introduced bill in Congress would grant workers up to 12 days of paid reproductive health leave each year, covering period pain, menopause, IVF, miscarriage, and endometriosis. The legislation responds to the fact that roughly half of women experience...

Kobe University researchers engineered a synthetic right‑handed (D) peptide that binds amyloid‑beta, the disordered protein driving Alzheimer’s plaques, and blocks its aggregation. In mouse brain cell cultures the mirror peptide restored cell viability to 100%, compared with 50% survival when...

The Fourth Circuit affirmed a preliminary injunction that blocks West Virginia’s Senate Bill 325, which would have forced drug manufacturers to extend 340B discounts to prescriptions filled by contract pharmacies. The injunction, originally issued by a West Virginia district court,...
GoHealth reported full‑year 2025 results showing a sharp decline in revenue and profitability as it intentionally scaled back Medicare Advantage activity. Net revenues dropped 55% to $361.8 million, and Adjusted EBITDA swung to a $35.1 million loss. The company emphasized a consumer‑first...
Company owner announced that the former chief financial officer has agreed to repay the $21 million he owes to the firm. The statement, reportedly supported by a video, aims to reassure stakeholders about the company’s financial stability. This repayment pledge follows...
Samantha Jacques, senior leader at McLaren Health Care, is spearheading a public‑private partnership through the Health Sector Coordinating Council to safeguard connected clinical environments. Her team delivers unified guidance that addresses the rising tide of cyber threats targeting hospitals and...
A coalition of 17 public‑health researchers and advocates from North America and Europe issued a joint statement calling for stricter regulation of glyphosate after a University of Washington symposium. They cite compelling evidence linking the herbicide to cancer, particularly non‑Hodgkin...
Joseph Mikhael, MD, highlights a dramatic shift in multiple myeloma care for older adults, driven by refined frailty assessments and the rise of targeted immunotherapies such as CAR‑T cells and bispecific antibodies. These advances have translated into higher survival rates...

Over the past two years, the HFMA Oklahoma Chapter partnered with the University of Oklahoma Hudson College of Public Health to embed HFMA certifications into the MHA curriculum. The collaboration has led 54 students to earn the Certified Specialist in...
Pennsylvania enacted Act 57 of 2025, creating an ENDS directory that limits market access to products with FDA PMTA approval before September 9, 2020. The law imposes a $50,000 surety bond, $2,000 per brand‑family and $200 per brand‑style certification fees, plus annual renewals, and...
Medical devices are becoming increasingly sophisticated, blurring the lines between engineering and information technology responsibilities, says McLaren Health Care’s Samantha Jacques, a HIMSS26 Changemaker Award winner. She argues that effective device management now demands close collaboration between clinical engineers and...

Pharmaceutical companies launched an eight‑day acquisition blitz, with six firms announcing deals worth about $25.5 billion. Two of those transactions involve upfront payments exceeding $5 billion each, underscoring the aggressive pace. The deals focus on securing biotech pipelines and specialty drug assets...
The phase 2 ACCESS trial demonstrated that post‑transplant cyclophosphamide (PTCy) combined with tacrolimus and MMF enables high‑survival outcomes for patients receiving mismatched unrelated donor peripheral blood stem cell transplants. One‑year overall survival reached 86% for donors mismatched at less than 7/8...
The Centers for Medicare & Medicaid Services issued a Quality and Safety Special Alert urging hospitals to redesign patient meals in line with the updated Dietary Guidelines for Americans, which prioritize fruits, vegetables, whole grains, and minimally processed proteins while...

The British Columbia Human Rights Tribunal dismissed a registered nurse's challenge to a COVID‑19 vaccine mandate, ruling that a vague medical note does not constitute a protected disability and that a genuinely held political belief does not exempt compliance with...
The U.S. Supreme Court issued an 8‑1 decision that treats gay conversion therapy for minors as protected speech, sharply limiting states' ability to ban the practice. Author Garrick Conley, whose memoir *Boy Erased* chronicled his own abusive experience, described the...

Haag‑Streit has launched its Metis 3D Digital Heads‑Up Module worldwide, extending the Metis 900 microscope line with a 4K, 3‑D visualization platform. The system places a high‑resolution screen in the surgeon’s line of sight, allowing a more upright posture and reducing neck...

MIT researchers unveiled a myoneural actuator (MNA) that rewires sensory nerves to transform existing muscle into a fatigue‑resistant, computer‑controlled motor for paralyzed organs. In rodent models the MNA restored intestinal squeezing and mimicked residual calf muscle function while sending sensory...

Researchers at Brown University analyzed over 75,000 low‑dose CT scans from the National Lung Screening Trial, covering more than 26,000 participants. They found that about 7% of exams contained significant incidental findings (SIFs) that were cancerous, and roughly 3% of...

Around 60 blood banks, including 29 charitable ones, operate in Lucknow despite repeated Food Safety and Drug Administration (FSDA) inspections that uncovered critical safety lapses. Inspections have repeatedly flagged missing testing equipment, absent qualified doctors, and poor record‑keeping, yet many...
CMS‑0057‑F, a new regulatory mandate, is prompting health plans to shift from viewing it as a compliance burden to a strategic advantage. Payers are aligning the rule’s four required APIs with business goals, automating prior‑authorization, and improving data sharing. By...
A six‑year, single‑center study of 1,001 eyes shows the PreserFlo MicroShunt dramatically lowers intraocular pressure (IOP) and medication use in glaucoma patients. IOP fell from a baseline 24.8 mmHg to 9.6 mmHg one day after surgery and remained around 13.7 mmHg through four...
Tenpoint Therapeutics announced that Yuvezzi, the first FDA‑approved eye‑drop for presbyopia, is now commercially available in the United States. The formulation combines carbachol 2.75 % and brimonidine tartrate 0.1 % to induce pupil constriction within 30 minutes, providing up to ten hours...
HFMA’s FastFinance newsletter has launched a podcast, offering finance leaders a new audio format for industry updates. A recent HFMA analysis reveals that non‑patient‑care services now generate the majority of hospital revenue, with patient‑care share varying widely by hospital type....

Researchers at Lund University have unveiled a deep joint‑learning AI model that can simultaneously identify five neurodegenerative conditions—including Alzheimer’s, Parkinson’s, ALS, frontotemporal dementia, and prior stroke—from a single blood sample. Trained on the Global Neurodegenerative Proteomics Consortium’s database of over...

The Nursing and Artificial Intelligence Innovation Consortium, led by FSU Dean Jing Wang, is tackling the gap between laboratory‑tested AI tools and real‑world nursing workflows. It aims to create national standards that embed nurses in AI‑enhanced clinical processes, ensuring predictions...

Vanda Pharmaceuticals reported that its NK1‑receptor antagonist tradipitant achieved its primary endpoint in a Phase II trial for gastroparesis, showing a roughly 30% improvement in nausea scores versus placebo. The data suggest the drug could address a sizable unmet need in...

A bipartisan Provider Reimbursement Stability Act of 2025 aims to halt the erosion of Medicare physician payments by capping annual cuts at 2.5 % and raising the budget‑neutrality threshold to $54.3 million, indexed to medical inflation. The bill also mandates five‑year reviews...

The American College of Lifestyle Medicine unveiled “Project Remission,” a digital film series highlighting how lifestyle‑medicine interventions can lead to type 2 diabetes remission. The series features real‑world case studies, expert interviews, and implementation models such as group visits and dedicated...

Colombo & Hurd secured an EB‑2 National Interest Waiver for a Colombian neurologist specializing in Alzheimer’s disease, enabling him to expand affordable, non‑pharmacologic care in underserved rural U.S. communities. The petition was approved in just three days with premium processing...

Stanford researchers engineered natural killer (NK) and cytotoxic T cells to overexpress metabolite‑sensing G protein‑coupled receptors, most notably GPR183, enabling the cells to home toward tumor‑derived metabolic cues. In mouse models of triple‑negative breast and ovarian cancer, GPR183‑enhanced NK‑92 cells...
A new longitudinal study of 4,015 Chinese adults aged 45 and older shows that adverse childhood experiences dramatically increase the likelihood of developing both clinical depression and a chronic physical disease later in life. Participants with four or more childhood...

Roxana Mehran, MD, an interventional cardiologist and professor at Icahn School of Medicine, began her one‑year term as president of the American College of Cardiology (ACC) at the ACC.26 conference in New Orleans. Mehran, a recognized leader in women’s heart health,...

Three Minneapolis‑area medtech startups—Person Health, Vail Scientific, and Peytant Solutions—will present technical talks at DeviceTalks Minnesota on May 4. Person Health is developing graphene‑based nanosensors for a non‑invasive breath test that detects early‑stage lung cancer. Vail Scientific offers a handheld breath...

Genetically modified pig livers have entered early clinical testing, with a Chinese patient surviving 171 days after transplantation. Researchers in China are exploring pig livers as auxiliary support, while a University of Pennsylvania team is evaluating extracorporeal pig livers as...
The Aston Ambulance Authority launched a 24/7 paramedic service on March 24, covering Aston Township, Lower Chichester, Trainer and Marcus Hook. The new operation employs 17 paramedics, an EMS chief and a medical director, filling the pre‑hospital care void left by the...

Ensemble, a leading revenue cycle management provider, and Cohere are expanding their partnership to create the healthcare industry’s first RCM‑native large language model. Unlike generic LLMs that rely on heavy prompt engineering, the new model is fine‑tuned from scratch on...

Oliver Robinson’s November 2023 suicide prompted a Manchester coroner to conclude that his privately prescribed medicinal cannabis probably contributed to his death. The inquest highlighted failures at Curaleaf Clinic, including reliance on outdated records and lack of coordination with NHS providers....