
Breakthrough Non‑Hormonal Male Pill Shows 95% Efficacy in Phase‑III Trials
A multinational research team announced a reversible, non‑hormonal male contraceptive pill that achieved 95% efficacy in Phase‑III trials. The compound was safe across a diverse cohort with no hormonal side effects, and participants regained normal fertility within three months after stopping treatment.
Also developing:
By the numbers: Gilead to acquire Tubulis for $5B
The Washington Post published a first‑person account of severe liver failure and a subsequent transplant after using a compounded GLP‑1 weight‑loss product. The story highlights the safety risks of off‑label, non‑FDA‑approved formulations that are increasingly marketed alongside AI‑driven GLP‑1 therapies. Industry observers note that the incident could trigger tighter scrutiny of AI‑enabled weight‑loss companies that rely on compounded drugs. Additionally, a new “Chief Health AI Transformation Officer” (CHAITO) role is being discussed to guide AI integration in health systems.
By now we have all read the piece in @nytimes about MEDVi's $1B+ business selling GLP-1s online with a ton of marketing, and very little ownership of infrastructure. I asked two friends @josh_tauber and @keatonbedell: - Is there any moat? (no) -...
Vision problems are rising among California children, yet only 16% of Medi‑Cal‑covered school‑age kids received a comprehensive eye exam between 2022 and 2024, down from 19% eight years earlier. The decline is statewide, with rural counties such as Colusa falling...
The U.S. Food and Drug Administration announced a formal review of novel dietary ingredients, including precision‑fermented supplements. The move aims to clarify safety standards and labeling rules for products that have surged in popularity. Industry leaders say the review could...
Most doctors will tell you your vitamin D is fine if it is above 30. That is not enough for fertility. Vitamin D receptors are on your ovarian follicles, your uterine lining, and your placenta. Women with levels above 30 ng/mL...

As a medical school professor, I was never taught this: meal timing may be more powerful than medication for gut disease. A new clinical trial in Gastroenterology found that intermittent fasting reduced Crohn's disease activity by 40%. Patients who restricted eating to...
Cognizant-owned health‑tech firm TriZetto disclosed a cyberattack that stole personal and medical information of more than 3.4 million patients. The breach, discovered in October 2025, may have lingered since November 2024, underscoring systemic vulnerabilities in health‑technology platforms.

Peptides—short chains of amino acids—are gaining popularity for weight loss, anti‑aging, and injury recovery. While prescription drugs like semaglutide and tirzepatide are FDA‑approved, most products marketed online are experimental, unregulated compounds such as BPC‑157, TB‑500, and CJC‑1295. Scientific reviews show...
Prilenia Therapeutics and Ferrer have opened enrollment for the PREVAiLS Phase 3 trial of pridopidine, a sigma‑1 receptor agonist, marking the only currently recruiting confirmatory study in amyotrophic lateral sclerosis. The trial will involve up to 500 participants across 60...
Hong Kong’s Hospital Authority announced a data breach that exposed the personal and medical records of more than 56,000 patients from hospitals in Kowloon East. The unauthorized retrieval included names, identification numbers, contact details and health information. Hong Kong’s privacy...
A retrospective study at Jinhua Central Hospital compared non‑intubated anesthesia with conventional endotracheal intubation in 55 lung‑cancer patients undergoing thoracoscopic surgery. The non‑intubated group showed earlier ambulation, more stable postoperative coagulation, and a reduced incidence of venous thromboembolism (VTE). No...

The American Board of Internal Medicine (ABIM) has linked internal‑medicine board exam scores to Medicare claims data in research studies without informing or obtaining consent from the physicians involved. By merging exam performance with National Provider Identifier and claims information,...

UK Defence Science and Technology Laboratory and the US DARPA conducted AI‑enabled battlefield medical triage trials, testing whether AI can be aligned with individual medics' ethical preferences. Simulated mass‑casualty scenarios in October 2025 let participants evaluate AI decisions without knowing...

As a medical school professor, I need to warn you: "diet" drinks may be just as dangerous as sugary ones for your liver. A major UK Biobank study of 124,000 people found: -- Artificially sweetened drinks raised liver disease risk by 60% --...

“Despite being one of the safest and most cost-effective permanent contraceptive methods, vasectomy is not guaranteed no-cost coverage under the Affordable Care Act’s preventive services mandate in the same way female contraception is.” Dominick Shattuck digs into vasectomy coverage (an...
A new study in the British Journal of Cancer identifies a molecular triad—nuclear fibroblast growth factor‑2 (FGF2), androgen receptor (AR), and Wnt pathway activation—that defines a targetable subset of antiprogestin‑resistant luminal breast cancer. The researchers demonstrated that nuclear FGF2 cooperates...
The Moreton Men Sports Group in Bury St Edmunds has swelled from 15 to over 200 members and now receives informal referrals from the Norfolk and Suffolk NHS Foundation Trust. By adding yoga and other low‑threshold activities, the group is...

Researchers at Keck Medicine of USC found that adults with metabolic dysfunction‑associated steatotic liver disease (MASLD) who engage in episodic heavy drinking—four or more drinks for women, five for men at least once a month—are about three times more likely...
Mizuho Securities lowered its price target for Autolus Therapeutics plc (NASDAQ:AUTL) to $10, down from $12, while keeping an Outperform rating. The adjustment follows Autolus' Q4 earnings, which posted a loss per share of $0.34 versus a $0.43 consensus estimate...
Clatsop County’s Emergency Medical Services Academy launched a free, four‑day summer program for 20 high‑school students, offering hands‑on training in CPR, ride‑alongs, and hospital tours. Funded by the Oregon Health Authority, the pilot immerses teens in ambulance, fire, and air‑medical...

1/ A new @CMSinnovates ACO model was released this week In our interview with @AbeSutton on the #ACOshow I teased him about how every new CMMI director seems to believe the world needs yet another primary care model (instead of improving...

Vietnam has dramatically reduced its infectious disease burden, cutting malaria cases by 78% and dengue hospitalizations by 45% over the past decade. The government pledged roughly $2 billion in U.S. dollars to modernize disease surveillance and expand vaccination programs. Despite these...
The MedHELM framework, built by Stanford’s CRFM, Stanford Healthcare, and Microsoft, introduces a clinician‑validated, 121‑task benchmark that evaluates large language models across the full spectrum of medical work. It replaces USMLE‑style exams with multi‑turn, longitudinal case vignettes covering decision support,...
K.C. Pharmaceuticals voluntarily recalled 3,111,072 bottles of over‑the‑counter eye drops sold at CVS, Walgreens, Kroger and other chains after the FDA identified a lack of assurance of sterility. The FDA classified the action as a Class II recall, prompting retailers to...
Vitals Vault announced the appointment of Dr. Robert Lufkin, a New York Times bestselling author and former UCLA/USC professor, as chief medical officer. The move is intended to sharpen the company’s AI‑based intelligence engine and expand its imaging services as it scales...
Novo Nordisk issued a press release claiming its Wegovy (semaglutide) tablets outperform the newly approved orforglipron (Foundayo) tablets, basing the claim on a simulated treatment comparison to be presented at the Obesity Medicine Association meeting. The article warns that such...

Joseph Masterson, a 63‑year‑old lawyer, survived a cardiac arrest and spent 18 days in the intensive care unit, including 14 on a ventilator. During his stay he developed delirium, required antipsychotics, and lost weight despite tube feeding. After discharge he...

KFF Health News spotlighted two pressing health issues this spring. On April 2, editor‑at‑large Céline Gounder discussed the FDA’s approval of a new weight‑loss pill during a CBS Mornings interview, outlining its clinical promise and market potential. A week earlier, Southern correspondent...
Why hospital systems fail to notice the human behind the bill [PODCAST] http://dlvr.it/TRsYCQ Podcast #EmergencyMedicine

Urgent care centers offer a faster, lower‑cost alternative to emergency rooms for non‑life‑threatening conditions such as minor fractures, cuts, and infections. By leveraging online check‑in tools, patients can reserve a spot and skip paperwork, cutting wait times dramatically. Visiting during...
Dental implant infections present early warning signs such as swelling, pain, bleeding, pus, or implant mobility. The article outlines safe home remedies—including salt‑water rinses, alcohol‑free antibacterial mouthwash, gentle brushing, cold compresses, and over‑the‑counter pain relievers—to manage mild cases. It also...

Chelsea and Westminster Hospital in London has become the first UK facility to employ an augmented reality system during pre‑surgical consultations for endometriosis. The AR platform, created by Medical iSight, projects anatomically accurate 3‑D models onto a headset, allowing patients...

Egg freezing has moved from a niche procedure to a growing option for UK women in their 20s and 30s, with private clinics charging roughly $4,500‑$8,300 per cycle plus annual storage and later IVF fees that can push total costs...
Feels like I’ve talked about everything — weight loss, GLP-1s, founder diaries… But have not formally introduced our platform. So here goes — MYRESET. — A next-generation digital health platform built for weight loss in Malaysia. Founded by doctors (myself + my co-founder), with real experience in telehealth...
Yes, health insurer and Silicon Valley owned AI companies are taping therapy sessions and using that data. It's a creepy situation driven by health insurers not wanting to pay for mental health care. https://t.co/zLyh5fcdvr

A new PLOS Medicine analysis of 27.8 million Medicare beneficiaries found that long‑term exposure to fine particulate matter (PM2.5) raises Alzheimer’s disease risk by about 8.5 % per incremental increase. The study shows the majority of the risk stems from direct brain...
This year 5 tech companies have introduced AI chatbots to consumers for health support @AnthropicAI @perplexity_ai @OpenAI @Microsoft @amazon @nicnguyen, a @WSJ journalist, tried some out. gift link https://t.co/vwO261Q6qB https://t.co/VFPyvc1P9O
Anyone have access to this paper? Rhizopus microsporus as Causative Agent of Mucormycosis in COVID-19 Patient https://t.co/Ao0uPXhzPY
Global Impact Wellness announced the launch of a new integrated mental health and substance‑use treatment program in Baltimore on April 3, 2026. The initiative combines psychiatric, counseling, and wellness services in a single, flexible outpatient model to address the city’s...
The Needs of Women Treated for Ovarian Cancer: Results From a #gyncsm Twitter Chat [Apr 26, 2018] @TLHagan et al. @JPCRR https://t.co/dOHPGvQ9Zy

COVID-19 in Patients With Gynecologic Cancer: A Report From the COVID-19 and Cancer Consortium [Mar 16, 2026] @AlainaJBrown et al. @COVID19nCCC @JCOOA_ASCO https://t.co/lZU3hFiNSS #gyncsm #CCC19 #COVID19nCancer #COVID19 https://t.co/mG18P0SHk3
A three‑year Korean trial of 3,000 patients with atherosclerotic disease found that aiming for an LDL‑cholesterol level below 55 mg/dL reduced major heart attacks, strokes and deaths by about a third compared with the conventional 70 mg/dL goal. Researchers say the result...

Association of Clinical Factors & Recent Anti-Cancer Therapy with COVID-19 Severity among Patients with Cancer: A Report from the COVID-19 and Cancer Consortium [3/18/21] @PGrivasMDPhD @arkhaki et al. @COVID19nCCC @Annals_Oncology https://t.co/WH5PPJySj6 #CCC19 #COVID19nCancer https://t.co/WN6maEUppn
The villain in health care is something called ‘value based care.’ Get rid of it.
Researchers at Stanford Medicine reported that a five‑day‑per‑month fasting‑mimicking diet (FMD) reduced inflammation and eased symptoms in about 66% of Crohn’s disease participants, offering a potential non‑steroidal treatment option.

Sharing Is Caring: #Healthcare Needs Its Own Humanity's Last Exam by @burhansebin @Forbes Learn more: https://t.co/LwritD6vmF #HealthTech #Tech #Technology https://t.co/gmyu9pmFVR
Epigenetic Clocks of Biological Aging and Risk of Incident Mild Cognitive Impairment and Dementia: The Women's Health Initiative Memory Study 🧠"These findings provide evidence linking epigenetic biomarkers of biological aging with MCI and dementia development, independent of chronological age." https://t.co/GKmn44gsqj
Pediatric leaders in India and the United States say co‑sleeping on a parents’ bed heightens Sudden Infant Death Syndrome (SIDS) risk, especially for pre‑term or low‑birth‑weight infants. The Indian Academy of Pediatrics and the American Academy of Pediatrics both endorse...
A Harvard‑led sub‑study of the COSMOS trial, published in Nature Medicine, reports that two years of daily Centrum Silver multivitamin‑mineral supplementation slowed biological aging by roughly 4‑5 months. The finding provides the first randomized, large‑scale evidence that an over‑the‑counter supplement...
The United States announced a 100% tariff on imported patented pharmaceuticals and ingredients effective July 31, while exempting generic drugs. The move targets a market that accounts for roughly 40% of India’s pharma exports and has triggered swift responses from Indian...