Sanofi Reports P-II Trial Results on Lunsekimig Across Multiple Immunology & Inflammatory Indications
Sanofi announced phase‑IIb results for its subcutaneous antibody lunsekimig across three inflammatory diseases. In the AIRCULES asthma study, the drug reduced exacerbations and improved pre‑bronchodilator FEV1 versus placebo, meeting both primary and key secondary endpoints. The DUET trial in chronic rhinosinusitis with nasal polyps also hit its primary nasal polyp score and showed significant improvements in congestion and LMK‑CT scores at week 24. In the VELVET atopic dermatitis study, lunsekimig missed the primary EASI change endpoint but achieved notable secondary outcomes such as EASI‑75 and vIGA‑AD 0/1.
I Style Homes Around How They Feel — These Are the 24 'Sensory' Products I Always Come Back To
The interior‑design world is shifting from purely visual aesthetics to sensory‑focused interiors, a movement rooted in neuroaesthetics that ties colour, texture, scent and light to mood and stress levels. Stylists like Iokasti Sotirakopoulou of Design Lab by Livingetc curate product...
On World Health Day: How Architecture Shapes Well-Being in Everyday Spaces
World Health Day 2026, themed “Together for health. Stand with science,” highlights the built environment’s influence on human well‑being. The article links architecture to mental health, showing how light, materiality, acoustics and biophilic design can reduce stress and improve cognition....
Porcelain Review: Peach PRC’s Debut LP Is a Candid Take on Young Queer Life
Australian singer‑songwriter Peach PRC released her debut LP *Porcelain*, a record that intertwines nature‑filled synth pop with candid reflections on young queer life. Critics applaud the autobiographical lyricism on tracks like “Celebrity Crush” and “Out Loud,” but fault the production...
VML Just Created the World’s First T-Rex Leather
Creative agency VML, The Organoid Company, and Lab‑Grown Leather have engineered the world’s first T‑Rex leather from reconstructed dinosaur collagen and turned it into a one‑of‑a‑kind luxury handbag. The piece debuted beside a massive T‑Rex statue at Amsterdam’s Art Zoo...
Springtime at Four Seasons Hotel Cairo at Nile Plaza
Four Seasons Hotel Cairo at Nile Plaza is celebrating Sham El Nessim with a curated spring program that blends Egyptian tradition and luxury hospitality. The centerpiece is an all‑day Egyptian feast at Zitouni on April 13, complemented by take‑away Easter treats from La...
Edgewood Tahoe Resort Joins Preferred Hotels & Resorts’ Legend Collection
Preferred Hotels & Resorts announced that Edgewood Tahoe Resort has been added to its Legend Collection, a curated portfolio of the world’s most distinguished independent luxury hotels. The resort, situated on 235 acres of Lake Tahoe’s south shore, offers 154...
Looking for a Fresh Take on a Classic Tubular Chair? Check Out This 1966 Reissue
The iconic CH66 chair, originally designed by Greek architect Nicos Zographos in 1966, has been reissued this year through a Karakter × Cassina collaboration and featured at Salone del Mobile 2026. The piece flips the classic Bauhaus cantilever into a B‑shaped silhouette...
Medical Crowdfunding in Mizoram Has No Shortcuts
Zo Inspiration Foundation, a people‑funded nonprofit in Mizoram, runs medical crowdfunding by locating patients, verifying needs, launching short‑term social‑media appeals, and tracking every rupee. It relies on about 80 recurring donors who give ₹1,000‑₹10,000 each month (approximately $12‑$120), covering both...
A Carpenter Explains How to Install a Loft Hatch for Easy Access to Your Attic
Homeowners seeking extra storage are turning to loft hatches, which combine a panel, frame, and often an integrated ladder for safe attic access. The guide outlines three main hatch types—hinged drop‑down, push‑up, and standalone ladder kits—and stresses precise measurements, joist...
'World First' Gene Project Helping Rare Monkeys
Researchers at Trentham Monkey Forest have achieved a world‑first by sequencing the complete genome of Crinkle, a Barbary macaque, providing the first full genetic reference for the endangered species. The reference genome enables scientists to assess genetic health, trace the...
"We Completely Avoided White" — How This Designer Used a Palette of Soft, Soothing Pigments to Create a Calming Home
Brian Woulfe, founder of Designed by Woulfe, transformed a Notting Hill apartment by deliberately avoiding white and embracing a palette of soft, creamy pigments. He applied liquid‑metal finishes to joinery, allowing the surfaces to develop a subtle patina that catches...
Biotalys Achieves First Milestone in Bioinsecticide Partnership with Syngenta
Biotalys announced it reached the first research milestone in its partnership with Syngenta to develop a novel protein‑based bioinsecticide using the AGROBODY™ platform. Laboratory tests showed promising in‑vitro activity against a key insect molecular target. The collaboration will now move...
Bon Iver Curates His Ultimate Tracklist on 'VOLUMES: ONE'
Bon Iver has issued its first non‑studio album, VOLUMES: ONE, a curated archive of live performances recorded between 2019 and 2023. The 11‑track collection pulls songs from ten shows across North America, Europe, Asia and Australia, featuring rare cuts like...
Sabrina Carpenter, Margaret Qualley, Madelyn Cline Make Grand Larceny Glam in ‘House Tour’ Video
Sabrina Carpenter’s new “House Tour” music video, co‑directed with actress Margaret Qualley, showcases a tongue‑in‑cheek mansion burglary starring Carpenter, Qualley and Madelyn Cline. The trio raids a lavish L.A. estate, pilfering wine, jewels and even a Grammy trophy before exiting...
Artemis, the Moon and the Case for Utopia
NASA’s Artemis II mission launched four astronauts on a 252,757‑mile journey around the Moon, marking the first crewed lunar flight since 1972. The program, projected to cost about $93 billion, is positioned as the first step toward a permanent lunar base. At...
The Brooch Is Back in Style – Here’s How to Make It Modern
The brooch is experiencing a revival on the Spring/Summer 2026 runways, with designers like Christian Dior and Saint Laurent reimagining it as a sculptural accent. Brands such as YSSO emphasize abstraction, weight, and texture, positioning the pin as a small art...
BOM: April to June 2026 Rainfall Outlook + VIDEO
The Australian Bureau of Meteorology projects below‑average rainfall for the April‑June 2026 period across most of the continent, with a 60‑80% chance of drier conditions in the Murray‑Darling Basin, eastern Tasmania and north‑west Australia. Far‑northern Queensland stands out as a...
#SHOWBIZ: Nora Ariffin Back in Her 20s Attire After Successful Weight Loss
Datuk Nora Ariffin, a 52‑year‑old Malaysian singer, shed 18 kg within two months after undergoing bariatric surgery. The rapid loss brought her BMI close to a healthy range and dramatically improved cholesterol and fatty‑liver markers. While she still aims for a...
Unpacking Saks Global’s Post-Bankruptcy Plan
Saks Global secured $500 million in post‑bankruptcy financing and aims to emerge from Chapter 11 by summer, backed by a total of $1.75 billion in court‑approved funding to stabilize vendor relationships. The luxury group’s leaner store footprint signals a shift toward a more...
BOM: April to June 2026 Rainfall Outlook
The Bureau of Meteorology’s April‑to‑June 2026 outlook predicts below‑average rainfall for most of Australia, with a 60 %‑80 % chance of drier conditions. Far northern Queensland is an exception, showing a 60 %‑80 % likelihood of above‑average precipitation, while parts of Western Australia and...
‘V’ for Veronica: Ines Di Santo’s Daughter Launches Bridal Diffusion Line
Veronica Di Santo, daughter of bridal powerhouse Ines Di Santo, has launched V, a new diffusion line aimed at modern brides for the Spring 2027 season. The line will debut alongside Ines Di Santo's main collection at New York Bridal...
Building a Global Movement: How Food Is Medicine Is Transforming Healthcare Worldwide
Researchers, clinicians, and funders from 12 countries gathered at the Rockefeller Foundation’s Bellagio Center in September 2025 to launch a global Food is Medicine (FIM) movement. The convening produced eight consensus principles that define how nutrition‑based interventions should be integrated,...
Bridal Manufacturers Face Tariffs and Rising Prices Amid Strong Appetite for Wedding Gowns
U.S. bridal manufacturers are grappling with rising fabric costs and 15‑20% tariff‑driven price hikes, yet designers like Sareh Nouri maintain stable pricing by emphasizing American‑made quality. The wedding market remains robust, projected to exceed $100 billion in 2025, with average dress...
Nardos Celebrates 10 Years
Luxury bridal designer Nardos Imam commemorated a decade in business with a high‑profile event at New York’s Rainbow Room, featuring a retrospective of her most iconic gowns and the debut of the spring 2027 collection. The showcase highlighted her signature fluid draping,...
Bridal Brands Katherine Tash, Ofrenda Studio Team Up
Los Angeles‑based bridal designer Katherine Tash is broadening her label with the Spring 2027 “Chrysalis” collection, adding ballgowns, A‑lines and luxe fabrics such as beaded lace, silk organza and jacquard. The debut includes a first‑ever partnership with Mexico City veil house...
Pratt Institute to Honor Designer Korina Emmerich With the 2026 Pratt Fashion Visionary Award
Pratt Institute will honor Indigenous designer Korina Emmerich with the 2026 Pratt Fashion Visionary Award, recognizing her work that fuses cultural heritage with climate‑justice design. Emmerich, founder of Emme Studio, has led initiatives such as Indigenous New York Fashion Week and held leadership...
‘The Brain, In Theory,’ an Excerpt
The excerpt argues that the brain cannot be considered a programmable computer because neither evolution nor synaptic plasticity provides arbitrary, user‑directed modifications of neural parameters. Evolution shapes brain structure indirectly through genetic constraints, not by encoding specific synaptic weights. Likewise,...
Single-Gene Systems-Level Effects, and More
A new preprint shows that SYNGAP1 haploinsufficiency in whole‑cortex mice creates two opposing cortical activity patterns, while disruption limited to excitatory neurons yields a single change. This dual effect points to systems‑level circuit maturation disruptions as a source of SYNGAP1‑related...
Inside Rue Madame’s Measured Expansion in China’s More Selective Consumer Era
Rue Madame has opened its third mainland China boutique in Nanjing’s Deji Plaza, joining stores in Guangzhou and Shenzhen. The concept blends luxury and fast‑fashion sensibilities, offering a curated mix of over 80 contemporary brands and weekly new arrivals. Founder...
Stop, Reduce or Stay on Antipsychotics After First-Episode Psychosis?
A recent pragmatic RCT followed 347 first‑episode psychosis patients to compare continued antipsychotic maintenance with gradual dose reduction or discontinuation. In the first year, the reduction group faced a higher relapse rate, lower quality of life, and increased mortality. By...
Regent Bali Canggu Brings Coastal Luxury to the Island’s Trendiest Beach Enclave
Regent Bali Canggu, the latest five‑star addition by IHG’s Regent brand, opened in Bali’s now‑trendiest beach enclave, Canggu. The resort features 150 suites and villas, nine pools, a beachfront restaurant called Beach House, and private‑pool penthouses, while maintaining a sense...
Computational Neuroscientist Keith Hengen Explains His Work Through Illustrations
Computational neuroscientist Keith Hengen, an associate professor at Washington University in St. Louis, has turned to hand‑crafted illustrations to make his research on neuronal networks more accessible. Using Adobe Illustrator and AI‑generated textures, he creates comic‑style visuals that precede the...
GMO Pictures May Reinforce Existing Views, Deepening the Divide of Attitudes Towards Them
A new study in the Journal of Science Communication examined how different images affect U.S. public attitudes toward genetically modified organisms. Researchers presented participants with either no image, a plain apple, or an apple paired with a syringe to suggest...
Major Grantmaker Restructures Staff to Better Deliver Upcoming Strategy
A leading charitable foundation announced a comprehensive staff restructuring to align its workforce with a forthcoming multi‑year strategic plan. The reorganization consolidates program teams, creates a new impact‑measurement unit, and adds senior roles focused on partnership development. Executives say the...
Elisabeth Waldo Dies at 107; Fused Indigenous and Western Music
Elisabeth Waldo, a classically trained violinist who studied under Jascha Heifetz and Efrem Zimbalist, died at 107 on March 16, 2026. After extensive travel in Latin America during the 1940s, she abandoned a purely Western repertoire and began fusing pre‑Columbian...
"My Role in Life Was to Be a Proud, Bold Lion, to Tell the Truth, and Stick up for What's...
Dave Mustaine announced that Megadeth’s self‑titled seventeenth album, released in January 2026, will be the band’s final record and tour. The album debuted at No. 1 on the US Billboard 200, marking the group’s highest chart achievement. Mustaine cited persistent hand...
Conrad and Grace Sewell Perform Exclusive Acoustic Version of ‘Firestone’
Conrad Sewell teamed with his Grammy‑nominated sister Grace for an exclusive acoustic rendition of his 2014 hit “Firestone,” filmed for Rolling Stone AU/NZ. The stripped‑back performance arrives as Sewell prepares to launch his “Bloodline Tour” across Australia this June. “Firestone,”...
The House of Time / Natura Futura
The House of Time, designed by Natura Futura in Babahoyo, Ecuador, reimagines domestic living as a rhythm synchronized with the river, climate, and local craftsmanship. Spanning 180 m² on a 23 × 13 m plot, the building uses interior courtyards, water features, and wooden...
Nurturing Wise Attention
In today’s always‑on environment, relentless notifications and algorithm‑driven feeds hijack our attention, flooding dopamine pathways much like slot machines. Stanford researchers show these reward loops can mirror the impact of alcohol or stronger substances, while minor algorithm tweaks can shift...
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Why So Many Kids Get Bored at School—And Ways Parents Can Help
School boredom affects many children, stemming from insufficient academic challenge, lack of relevance, mental‑health struggles, or weak social connections. Experts like Dr. Natalie Gwyn and social worker Tameko Hairston‑Piggee note that unaddressed disengagement can lead to apathy, frustration, and even...
Renesas Rad-Hard ICs Aboard NASA’s Artemis II
Renesas Electronics’ radiation‑hardened integrated circuits are aboard NASA’s Artemis II mission, which launched on April 1 from Kennedy Space Center. The Intersil‑branded rad‑hard ICs are embedded in Orion’s avionics and the Space Launch System, managing power distribution, signal integrity and onboard computing...
Want to Write Better? 3 Books to Improve Writing Skills
The article highlights three essential books—Stephen King’s *On Writing*, Strunk & White’s *The Elements of Style*, and Anne Lamott’s *Bird by Bird*—as practical guides for anyone looking to sharpen their writing. It argues that writing is a skill that can be taught...
The Brick House / Studio VDGA
The Brick House, a 4,500‑sq‑ft private residence in Pune, tackles tight urban site constraints by stacking living spaces across four levels and inserting micro‑courtyards that act as light wells and ventilation shafts. Brick jali screens envelope the façade, filtering solar...
Couture Cuisine: Why Fashion Brands Are Pivoting to In-Store Dining
Luxury fashion houses are expanding into in‑store dining as millennials and Gen Z prioritize experiences over possessions, with 78% of the former preferring events to products. The trend follows a slowdown in traditional growth markets like China, prompting brands to create...
Griefdogg Review: Michael Winkler Pulls Australian Fiction in Brave New Directions
Australian author Michael Winkler’s second novel, Griefdogg, follows the surreal transformation of hydrologist Jeffrey into a self‑designated family pet after inheriting a seven‑figure sum (approximately $1‑$9 million). The book employs a non‑chronological, stream‑of‑consciousness narrative peppered with Australian colloquialisms, scientific digressions and...
Lady Gaga Cancels Final Montreal Show Due To Respiratory Infection: “Absolutely Heartbroken And So Sorry”
Lady Gaga canceled her final Montreal concert at the Bell Centre after her doctor warned against performing due to a worsening respiratory infection. She announced the cancellation on Instagram just hours before the show was set to begin. The tour will...
Pullman Dubai Creek City Centre Launches Staycation With Retail Benefits
Pullman Dubai Creek City Centre has unveiled a staycation package that includes a AED 100 (≈$27) shopping voucher for the adjacent City Centre Deira mall, plus unrestricted use of its fitness centre, spa, rooftop pool and padel court. Accor Live Limitless...
Is the Galápagos Damselfish Extinct?
The Galápagos damselfish (Azurina eupalama) has not been recorded since 1983, leading researchers to deem it likely extinct. A study by Jack Stein Grove and Benjamin Victor compiled historical records and decades of failed surveys, linking the disappearance to the...
£10.4m UK Project Will Grow Next-Gen Materials
The UK’s Engineering and Physical Sciences Research Council has awarded £10.4 million to a five‑year EXPRESS programme led by the Universities of Warwick and Southampton. The project will develop electrochemical electrodeposition techniques, guided by bespoke precursor chemistry, to grow high‑quality transition...