Ivonescimab Plus Chemo Rivals Tislelizumab in First‑line sqNSCLC
#ASCO26 LBA4 - Zhiwei - Ivonescimab + chemo vs tislelizumab + chemo 1L sq NSCLC - Ph3 HARMONi-6 [May 31, 2026] Zhiwei et al. https://t.co/oWEeVo2oyq #NCT05840016 #lcsm #ImmunoOnc https://t.co/NP2qr2gPuY
Bacterial Flagellar Motor Revealed as Proton-Powered Electric Engine
After 50 years, the flagellar motor used by bacteria is finally understood. It's a true electric motor that funnels and unbinds protons to produce torque. beautifully explained by Pulizter winner Natalie Wolchover: https://www.quantamagazine.org/what-physical-life-force-turns-biologys-wheels-20260420/
Lyrical Lemonade Summer Smash Sounds Completely Fabricated
'The Lyrical Lemonade Summer Smash at SeatGeek Stadium in Bridgeview, Illinois' is the most made up-sounding concert of all time
90‑95% of Cancers Stem From Lifestyle, Not Genes
From all the way back in 2008. "Only 5–10% of all cancer cases can be attributed to genetic defects, whereas the remaining 90–95% have their roots in the environment and lifestyle" https://t.co/Fjd6izZyuT https://t.co/j8mh4DEqeU
Phase 3 Trial Shows Abemaciclib Benefits Advanced Liposarcoma
#ASCO26 LBA2 - Dickson -SARC041: Ph3 DBRCT abemaciclib vs placebo in Pts w/ adv dedifferentiated liposarcoma [May 31, 2026] https://t.co/oWEeVo2oyq #NCT04967521 #scmsm https://t.co/uD6A9JmBCn
New Model Enables Multi‑Institutional Sarcoma Video Collaboration
A model for multi-institutional, multidisciplinary sarcoma videoconferencing [2013] Attia, Maki, @JTrentMDPhD , Okuno, Indelicato, @nickwebbermd , Curtis, Kozak #ASCO13 Abstr 10521 https://t.co/opAHZRDTTr #scmsm
Genomic Profiling Boosts Survival for Advanced Sarcoma Patients
Using Tumor Genomic Profiling to Guide Treatment Selection Extends Survival in Advanced Sarcoma [May 10, 2019] @ASCO Daily News #scmsm #PrecisionMedicine https://t.co/8625ixTvQu
Creator Economy Thrives: Artists Earn More, Stay Independent
The @contra team published compelling research that disproves all of the AI doommaxxing being sold to creatives. Artists are making more art, earning more money, and staying independent. I’d argue the Creator Economy is stronger now than it was 5...
Racket Sports Slash Mortality, Boost Heart and Brain Health
Racket sports are linked with some of the largest reductions in all-cause mortality among common physical activities. The mix of short intense bursts, brief recovery, balance, coordination, and fast reactions is great for heart and brain health. Take this as...
Perioperative
#ASCO26 LBA1 - Taplin - Perioperative APA + ADT - prostate CA [May 31, 2026] https://t.co/oWEeVo2oyq #NCT03767244 #pcsm https://t.co/8o91ntAwL9
Gentle Empathy Defies Parents'
This story describes the worst nightmare of any parent and is, if anything, far too kind to the people who deliberately put everyone around them at risk of it. Probably the gentle, blame-free approach is the more effective one but...
Boston Marathon Record Scrutinized Amid Carb‑free Elite Trends
Our latest Spotlight podcast. We focus on the #bostonmarathon course record, and wonder whether it's really a "truly great" performance? Also, are elites avoiding carbs? Noakes thinks so, based on TV coverage (really). And stress-induced anti-doping denial https://t.co/2RLOmWsGWO
Transparency and Trust Foster Ownership and Performance
This went around a few years ago a lumber mill puts machine prices on the door to remind operators of responsibility. - I’ve never seen an employer lose by sharing information with their people. - But price alone doesn’t create ownership. Training purpose and...
Richard Gadd's 'Half Man' Trailer Explores Modern Masculinity
Behind the Story Promo Video for 'Half Man' Richard Gadd's New Series https://t.co/W54Al0CyfD #HalfMan #JamieBell #RichardGadd #masculinity #HBO #BBC https://t.co/xKUzMiPtVm
Three Key Nutrients for Brain Longevity, Plus Polyphenols
As a bioscientist studying aging, my top 3 nutrients for brain longevity are: → Omega-3s (fatty fish 2–3x/week) → Vitamin B12 (beef, dairy) → Choline (2 eggs daily) Plus plenty of polyphenol-rich foods: berries, extra virgin olive oil, cocoa, nuts, and coffee.
Artists Back AI Amid Hidden Funding to Repair Image
What's behind Diplo (and other artists) pushing so hard for AI? We need to talk about the quiet investments and bags creatives are getting to fix AI's publicity problem. https://t.co/NU4ssTuxLP https://t.co/kkEE5KHyyU
Injured Runners Need Physical & Mental Support
A few people in my community forwarded me a video of a runner deciding to toe the line of the Boston marathon with a pelvic fracture asking if I saw it (no I had not). I really hope that this...
Embrace Feedback to Continuously Evolve and Thrive
One of the most beautiful things about life is that we are constantly evolving and learning. With effort, we can continue to grow and become better and better at our job and in our relationships. If we are open to...
Daily Reading Compounds: 3,000 Hours Transforms Life
I read for 30-60 minutes every day for 10 years. That's roughly 3,000 hours of skill building. While others scrolled Instagram. While others watched Netflix. While others complained about their manager. I compounded. You can't read every day for 5 years and NOT wake up to...
Bet on Yourself: Risk Outpaces Comfort Zone
It makes sense to take risks. Your comfort zone guarantees failure. But every risk is a chance to win. I’d rather bet on myself than guarantee a loss.
Doctor’s Insider Tips to Ease NAD IV Experience
Feel “weird” during an NAD IV? Here are the insider tips from a top doctor, @joseph_purita, to make things smoother:
Milan Design Week Day 2: Hermes,
Day 2 impressions of Milan Design Week - highlights include the hammered metal and leather pieces from @hermes, a hotel courtyard takeover by joyful @marimekko and nickvinson sublime translation of #garyhume and #martinogamper language into leather and metal forms. #design...
When Recovery Fails, Overtraining Triggers Injury
A 47-year-old runner came to see me many months after surgery. His knee hurt. We dove deeper. He had returned to training, but recently his times had slowed, his heart rate had risen, and his legs had felt heavy. What...
Adding Tasks Just for the Satisfaction of Crossing Them Off
Not me adding things to my To Do list just so I can cross them off. https://t.co/XfwBRX2y1X
WGS Uncovers Clinically Relevant Findings Missed in MDS
Whole genome sequencing [WGS] to identify novel, clinically relevant findings missed by standard of care for Pts w/ myelodysplastic syndrome [MDS] - @AlexBataller etal @garciamanero @UTMDAnderson @TempusAI #ASCO26 abst 6570 Pst 363 https://t.co/t7aNW89eRL #MDSsm #leusm #cagenome
First Trial Shows Best‑in‑Class NLRP3 Inhibitor Promise
Excited to complete our first clinical trial for BGE-102. Clinical data supporting best-in-class potential, built on new chemistry and a novel binding site targeting NLRP3 - a central driver of of chronic inflammation in aging. On to Phase 2!
AQUARIUS Registry Uncovers Biomarkers in Blood Cancers
AQUARIUS: A longitudinal multi-center molecular biomarker discovery registry for Pts w/ hematologic malignancies - @mtmdphd et al. @TempusAI & IFLI - Instit Follicular Lymphoma Innovation #ASCO26 abstr TPS7105, Poster 599a https://t.co/70G0v1P968 #NCT07154823 #lymsm #cagenome
Turn Aerobic Base Work Into Novel Experiments
The Glycolytic Trap & “The Variety Junkie” Low-intensity aerobic work is the most predictable, repetitive training there is. This nervous system is destabilized at the thought of LISS as it feels like a slow death. They gravitate to glycolytic training...
Stop Chasing Routines; Success Needs Less Effort
Guess what? You don’t need another routine. You don’t need more discipline. You don’t need to “try harder.”
First Look at Sébastien Vanicek’s Evil Dead Burn
Must See Teaser for Sébastien Vanicek's 'Evil Dead Burn' Horror Film https://t.co/t1nKxsy4PB #EvilDeadBurn #SamRaimi #horror #SebastienVanicek #Deadites https://t.co/ciFrqEXEGj
He Loved Them so Much He Blurbed Multiple Times
And they are good (he said, having blurbed at least a couple because he enjoyed them that much)!
Winners Act First, Losers Wait for Understanding
after 5,000+ clients and i can tell you exactly what separates winners from losers: The winners implement before they understand. The losers wait until they understand before they implement. Systems work before you believe in them. that's the whole point.
Intelligent Robots Streamline Operations in Modern Bakeries
Romias #Robotics Builds Intelligent #Robot System to Support Modern Bakeries by @lukas_m_ziegler #FoodTech #Innovation #EmergingTech #TechForGood https://t.co/4lqaHVMyH0
Free Documentary Explores Psychedelics, Awareness, and Meditation
New and free documentary on psychedelics, awareness, and meditation, exec produced by Sam Harris. https://t.co/gwXTLJSP06
High Sodium Accelerates Memory Decline in Older Men
Higher sodium intake is associated with episodic memory decline in cognitively unimpaired older males: A 6-year longitudinal study https://t.co/8snYRP7sRR https://t.co/kDhs9b2Y8s
Stop App‑hopping; Adopt a Repeatable Productivity System
Downloaded another productivity app? Yeah… that’s not the solution. Switching tools feels like progress but nothing actually gets done. What you need isn’t more apps. You need a system that works. Collect what’s on your mind Organise what matters Do what’s scheduled Simple. Repeatable. No chaos. Try the COD Method...
You Can Be a Savage Founder and Family Man
The strongest "message" is not anything said ... but seeing what people around you are DOING I got married and started my first company at 24. We had 3 kids by 31. But living downtown, I did not know anyone who...
Growth Demands Leaving Comfort Behind
You cannot step into the greatest version of yourself while you're still clinging to comfort.
Aim for 120 Minutes of Nature Weekly for Wellbeing
There are recommendations to spend 120 minutes in nature each week. Do you enjoy time in nature? If so, what do you do? With the season changing soon, we'll have different opportunities to enjoy the world around us. #nature #Health...
BookCon Highlights Publishing's Author‑Indie Consumer Shift
This year's BookCon definitely underlines one of the greatest transformations in book publishing in the last 10 years. It is more author-driven, indie-driven, and consumer-driven than ever before. BookCon can succeed and grow; the industry-facing BookExpo remains as dead as...
Michael's Rotten Tomatoes Score Plummets to 29%
3 hours since review embargo was lifted for #Michael. RT critics score sinks to 29% from 58 reviews. Will have one of the lowest RT scores in recent months for a film opening #1 at wknd #boxoffice. https://t.co/MKcGUYRG7I
Publish, Promote, and Avoid Arguments to Outpace Mediocrity
Mediocre creators aren't beating you because they're better. They're beating you because they publish while you hesitate. They're beating you because they promote their work without fear. They're beating you because they're not arguing with people on the internet.
Unconscious Self‑Sabotage Undermines Confidence and Preparation
In today’s edition of The Psychology Lab, I discuss the phenomenon of ‘psyching yourself out’ and how our unconscious mind can lead us to self-sabotage by messing with our confidence and preparation. https://t.co/222FEdOoqu
Pressing Tongue to Roof Boosts Strength and Sleep
Tongue exercises (eg opening mouth and slowly circling rim of mouth 5-10x, or pressing tongue from tip snaking to the back to roof of mouth 10-20x) daily we’ve seen change sleep and mechanics.
Radical Acceptance: Stop Fighting Reality, Not Endorsing It
Radical acceptance doesn't mean you're okay with what happened, it means you stop fighting the fact that it did.
ASCO26 Unveils Pancreatic
#ASCO26 abstract titles were released today: $RVMD RASolute Ph3 study in pancreatic cancer will be presented during the plenary session. Also, Akeso $SMMT ivonescimab HARMONi-6 trial in lung cancer. China-only data.
Pretentious Reviewer Slams Film; Michael Is Horrid
This is precisely the expected reaction from the chin-stroking, zero-fun, mega-pretentious Robert Daniels Zero relatability with the average moviegoer (This said, if I hate this film, I’ll come back and say dude was in the ballpark)
Failure Repeatedly Fuels Success, Says Michael Jordan
I have missed more than 9,000 shots in my career. I have lost almost 300 games. 26 times I have been trusted to take the game's winning shot and missed. I have failed over and over and over again in...
AI-Driven Medicine and Cars to Extend Productive Life
Extending human productive life and restoring lost function should be the ultimate objective of AI-powered discovery medicine. It was a great pleasure to share some the story, current progress and long-term plans at one of the most impactful events of...
Dark Matter Passes New Cosmic Test, MOND Fails
Dark matter passes a new cosmic test, while MOND fails A new cosmic test has finally, with CMB and large-scale structure data, become realistic: using the kinetic Sunyaev-Zel'dovich effect to test dark matter vs. MOND. Guess who wins? https://t.co/jja8ObZ5OQ