13 Years Later, The National’s Melancholy Masterpiece Endures
13 years ago today, The National released Trouble Will Find Me—a beautifully brooding album filled with existential poetry, aching melodies, earned a Grammy nod, and solidified their place as masters of melancholy. https://t.co/nUq2CqrHpP
Zusduri Demonstrates Real-World Efficacy for Low-Grade UTUC
UroGen’s Zusduri shows strong real-world results for low-grade upper tract urothelial cancer, matching clinical trial efficacy. A promising kidney-sparing option, though durability and reimbursement remain key hurdles. Urology
Unsaturated Fats Improve Sleep and Gut Health in Aging Flies
Dietary unsaturated fatty acids distinctly associate with the early age sleep–wake cycle and gut integrity in aged fruit flies, Drosophila melanogaster https://t.co/4HzgwbAgR5 https://t.co/LGpfDjfeXu
Sunday Blueprint: Faith, Fitness, Food, and Family
The best Sunday? -Wake up & pray -Take a walk -Bible & coffee -High protein breakfast -Head to church -Nature -Something active -Read -Cold plunge + sauna -Spend time with community/family -Prep healthy food for the week -Journal 5 things you’re grateful for -Healthy dinner -Evening walk -Evening prayer -Early bedtime Start...
Alzheimer’s Prevention Begins Decades Early with Hormones, Sleep, Muscle
Alzheimer’s doesn’t start with memory loss. It starts decades earlier: through hormonal decline, poor sleep, metabolic dysfunction, inflammation, and loss of muscle. For women, menopause is a major neurological transition, not just a hormonal one. Protecting estrogen balance, preserving muscle, prioritizing deep sleep,...
Joining CNN Sunday to Discuss Ebola PHEIC
I’m scheduled for around 5:30 PM Eastern this Sunday PM @CNN to discuss the Ebola PHEIC and all things infectious
Reading Boosts Cognitive Reserve, Cuts Alzheimer Risk 38%
A Lifetime of Reading and Learning Linked to 38% Lower Alzheimer's Risk As a medical school professor, I have watched cognitive reserve go from a fuzzy idea to a measurable signal. A new study just put hard numbers on it. (1/5)
Irregular Bedtimes May Double Heart Attack Risk
Going to Bed at Random Times May Double Your Heart Attack Risk As a medical school professor, I teach that sleep quantity matters. What I am updating is how much sleep TIMING matters -- often more than total hours. A new 10-year...
Your “Too Much” Self Is Finally Becoming Whole
The version of you that people called “too much”… may have just been finally becoming whole.
Infant Constipation Tips for Expectant Parents – Free Guide
🌟Are you expecting a baby?comment ROADMAP for a free guide for expectant parents 🧩Constipation can be a very uncomfortable thing for an infant. While it can
The Devil Wears Prada 2 Tops $500M, Outshines Mandalorian
#TheDevilWearsPrada2 surpasses $500M mark globally with $18M third weekend stateside Film has amassed $370.3M overseas, $175.9M stateside for $546.2M worldwide Could this actually be a bigger global film for Disney than #TheMandalorian? https://t.co/Uc6dCTo8sT
ObsessionMovie Tops BIG with $16.1M Debut
#ObsessionMovie outperforms BIG with $16.1M debut stateside AMC Burbank the film’s biggest earner with 2X LIVE cast Q&As Saturday night And so the legend of Curry Barker begins https://t.co/BjksVzSZvf
Make Consistency So Easy, Intensity Becomes Irrelevant
The biggest lever isn't workout intensity. It's building a life that makes consistency boringly easy. Same routes. Same time of day. Same low ego pace. Do that for a few years and "fitness hacks" start looking very silly.
Chinese Team Sets 27.17% Record for Inverted Perovskite Cells
Chinese researchers achieve world-record efficiency of 27.17% for inverted perovskite solar cell #energysky -- via pv magazine global: https://t.co/9gv84zD7sb
AI-Driven Anti‑Aging Pipeline Leads Pharma, Yet Remains Niche
I just found an old T-shirt from 2016 with my one true mission. Since then, we took the lead in AI drug discovery in general and pharma is still a bit cold when it comes to aging so we had...
VSV Ebola Vaccine Protects Zaire, Struggles with Bundibugyo
1/n Been asked about potential X-protection of current VSV Ebola, which shows excellent protection vs Zaire strain, compared to the new epidemic strain, Bundibugyo, doesn’t look all that promising unfortunately, but with resources it’s possible to move quickly, some info...
Silence Carries Weight in Strout's The Things We Never Say
The Weight of the Unspoken: Elizabeth Strout's Departure in "The Things We Never Say https://t.co/2G8GTChp7V
Intensity Beats Volume, Yet Media Overstated Its Meaning
Intensity or volume? A recent paper got the world abuzz with a clear message… intensity led to far greater health effects than volume. However, every journalist who reported on this paper seriously overestimated what the authors meant by intense. I...
SpaceX Launches Actual Cloud Computing Above Earth
Introducing the SpaceX Literal Cloud Finally, cloud computing that is actually taking place miles above your head https://t.co/Djft4IFsk1
Think for Yourself: The Rare Key to Authentic Living
Thinking for yourself is incredibly rare. Most do not realise how much they are influenced by others. But it’s the skill that will get you furthest. Because the people who think for themselves end up living lives that look like their own. Most live...
Apathy Signals Broken Systems, Not Employee Laziness
Apathy at work is not always laziness. Sometimes, it is a perfectly rational response to a broken system. This Office Space scene still hits because it explains something many companies refuse to admit: People do not stop caring randomly. They stop caring when the...
Overactive Muscle mTORC1 Blunts Endurance Gains
Hyperactive Muscle mTORC1 Attenuates Functional Adaptations to Endurance Training Despite Alterations in Mitochondrial and Lipid Profiles "hyperactive mTORC1 in muscle may attenuate functional adaptations to endurance exercise training, despite increasing mitochondrial respiration and alterations in lipid metabolism." https://t.co/JxZjWmoIle
Use Positive Reinforcement to End ADHD Arguments Quickly
A child psychologist trick: the fastest way to reduce arguing after correcting an ADHD child.
New Paper Outlines Emissions Scenarios for IPCC AR7
Thats certainly a take. Here is what the new paper introducing the emissions scenarios we are using in the upcoming IPCC 7th Assessment Report actually says: https://t.co/KiwY0IANWW
Sunday Mornings Spark Our Biggest Product Breakthroughs
Sunday morning, coffee, no meetings on the calendar. This is the only window of the week where I can actually think about the product instead of reacting to it. Everything important I've shipped in the last six months started in a...
70% Connection, 30% Correction Transforms Child Behavior
Your child isn’t “difficult.” They’re disconnected. 70% connection, 30% correction changes everything. Comment “7030” if you want practical examples to apply this rule at home ...starting today. [emotional safety, child psychology, behaviour management, conscious parenting, parent child bonding]
Calorie Restriction Deactivates Complement C3a, Slowing Inflammaging
Exoproteome of calorie-restricted humans identifies complement deactivation as an immunometabolic checkpoint reducing inflammaging Complement C3a reduction is a metabolically regulated inflammatory checkpoint that can be harnessed to attenuate inflammaging. https://t.co/UaBPbf84pM
Bitter Experiences: Choose Wisdom over Wound
If bitter experiences happen in your life, the Choice is this – you can either become wise or wounded. #SadhguruQuotes https://t.co/vejPAUgCfl
B‑movie “Deep Water” Serves Absurd Shark Mayhem
A plane full of one-dimensional characters crashes into the ocean, just to meet a school of weirdly smart and bloodthirsty sharks in the B-movie action film "Deep Water". Here's my toothy review: https://t.co/zPDJtC7MMN #film #movies #sharks https://t.co/1cwQHjRTiA
Third Trial Shows No Expectancy Effect in Psychedelic Medicine
Just seen third replication of lack of expectancy to response prediction in psychedelic medicine trial. That’s 3/3 of my last 3 trials. Why won’t other teams test and report on this? See 2 new trials coming soon that replicate null...
Frailty Index Uncovers Distinct Risks for 17 Outcomes
Frailty index predicts the risk of 17 health outcomes in distinct ways: prospective findings from the Moli-sani Study https://t.co/u8bn9owyoU https://t.co/CentdF7zz2
Adam Driver Shines in Gray’s Devastating Mob Tragedy
Paper Tiger: Adam Driver gives the best performance of his career in James Gray’s devastating tragedy in a teapot about two brothers who get mixed up with the mob. An incredible, thrilling film, and a big gift for We Own...
Target Glute Max as Hip External Rotator in Gym
Love this variation from bostonbarbellofficial ! I love working the glute max as a hip external rotator. You see it worked this way in sports all the time but in the weight room it’s harder to carry out.
Modern Overstimulation Undermines High Performers' Regulation
Most high performers do not have a discipline problem. They have a regulation problem. And modern life is making it worse. Here is what nobody talks about: The human nervous system was not designed for: Constant notifications Infinite scrolling Artificial light at midnight Morning phone addiction Endless caffeine 24/7 urgency Information...
Oddly Specific First-Week Tips
What oddly specific tips would you give a first time parent during their very first week with baby? 
AGEs Emerge as Robust Biomarkers Across Diseases
Glycation and disease: a systematic review of the analytical methods and applications of advanced glycation end products (AGEs) as biomarkers of disease https://t.co/3hqX4iXETc?
Expert Wei Debunks PRME Failure Claims with CRISPR Insight
Here is a great overview by one of the most educated & knowledgeable people on 𝕏 and a personal friend - @zhaoweiasu, in which he rebutted the argument that $PRME has failed to deliver on its business model. As an...
Joshua Redman's Tiny Desk Jazz Masterclass Reimagines Classics
Joshua Redman’s Tiny Desk set is a masterclass in jazz with purpose. With Gabrielle Cavassa, he reimagines “Chicago Blues” and “Streets of Philadelphia” before delivering the soul-searing “After Minneapolis.” https://t.co/ZGqhn2PLJQ
Lee Brice Drops Acoustic Single Ahead of Sunriser
Lee Brice's "Country Nowadays" is out now, a straight-talking acoustic confessional that sets the tone for his new album 'Sunriser', arriving June 5. 16 songs for everyone who earns their sunrise. https://t.co/U8uSYBuroA
Bebe Rexha Drops Albanian‑infused House Anthem “Çike Çike”
Bebe Rexha's "Çike Çike" is a bass-heavy house anthem built on Albanian heritage and peak-hour energy. The video is out now and the album 'Dirty Blonde' drops June 12. This one hits from the first beat. https://t.co/luc3xuCsDZ
Geroscience Drives Precision Geromedicine and Targeted Therapies
Beyond disease treatment and prevention: From geroscience and molecular hallmarks to gerotherapeutics and precision geromedicine https://t.co/cXkWAyj3Cd
Power Training Boosts Functional Mobility in Older Adults
Our meta-analysis, led by @ExerciseBiology, compared power training (performing the concentric phase explosively with a controlled eccentric action) vs traditional strength training tempos in adults aged 60 years and older. Results indicated that power training produced a modest...
Your Home Environment Shapes Mental Health Daily
We talk about what we eat, how we sleep, how we move. Nobody talks about the fact that the space you live in is affecting your mental health every single day. I wrote about how to fix that. Link ⤵️
True Success Demands Years, Not Months of Effort
I trained for four years to run for only nine seconds. There are people who, because they do not see results in two months, give up and quit. Sometimes failure is brought on by oneself. —@usainbolt, the world’s fastest man https://t.co/kRskc7zx9Z
Katherine Johnson Stresses Math's Vital Role in Space
Katherine Johnson, the brilliant mathematician who helped @NASA put a man on the Moon talks about the importance of math https://t.co/bgRPTeCXVc
CRISPR Shifts to DNA‑guided RNA Targeting
Expanding the CRISPR genome editing toolkit: A flip from RNA-guided DNA targeting to DNA-guided RNA targeting @NatureBiotech https://t.co/GxKVthgbxh https://t.co/UIifna0nsF https://t.co/2ZB1eJzpCe
Give Yourself the Gift of Daily Mindfulness
Mindfulness--feeling fully present in the present moment is a present you can give to yourself everyday. 🌸 Take the time to be mindful. 💗 #SaturdayMorning #SaturdayMotivation #SaturdayVibes #Mindfulness https://t.co/qGxAAmnZL1
Michael Movie Defies Critics, Returns to Box Office #1
All signs point to #MichaelMovie returning to the #1 position with an estimated $27M fourth weekend as it’s already cleared $600M+ globally and holds continue to be strong at roughly -30% this weekend So those agenda-driven critics had ZERO effect on...
Identify a Responsive Nervous System with Four Signs
4 Signs You Have A Responsive Rather Than Reactive Nervous System: 1. Adaptability. 2. Non-Attachment to Triggers. 3. Active Listening. 4. Self-Compassion.
Socializing Grows Older Adults' Brain Volume
Socializing increases brain volume in older adults 120 adults aged 60–79 were randomized into 4 groups for 40 weeks: - Tai Chi → ~0.47% increase in brain volume - Social interaction → ~0.41% increase - Walking → slight decline - No intervention → ~0.24%...