New Drug Could Eradicate Sleeping Sickness, Says NPR
Sleeping sickness could be wiped out with this new drug: my comments @NPR @NPRGlobalHealth https://t.co/T0mAeX8P0A

Can NAD⁺ Manipulation Extend Human Healthspan?
NAD for Health: Opportunities & Challenges 2026 This international conference will explore a central question in aging research: can manipulation of nicotinamide adenine dinucleotide (NAD⁺) metabolism enhance human healthspan and prevent age-related diseases? https://t.co/bEtQPmUnSh

Enter Audemars, Leave with Your Dream Watch
Dream scenario. Walk into your AD. Walk out with your grail. #rolex #patekphilippe #audemarspiguet #richardmille #fpjpourne

Master CGM Data Interpretation – Early Bird Ends Soon
Learn how to interpret CGM data correctly during training. 24h left to use the early bird discount. Webinar 25 March | 16:00-18:00 CET https://t.co/eN6PetWMGW https://t.co/1HxlnKcV5K
British Airways Revives Melbourne Service After 20 Years
After roughly 20 years, British Airways will be returning to Melbourne, Australia, thanks to a new fifth freedom Dreamliner route. https://t.co/LHsAw9hksw
Embrace Adversity: Gratitude Fuels Future Achievements
"Adversity is a terrible thing to waste. I look back at my most difficult moments with gratitude; had they not happened, I wouldn’t have achieved what I did next." -Will Guidara (EP.492) With thanks to @AlphaSenseInc, @MorningstarInc, and Ridgeline.
The One Must‑Read Book for Youth Financial Literacy
What is one book that every young person must read if they want to build financial literacy? ⬇️
Emotional Mastery, Not Intelligence, Drives Trading Success
The difference between those who eventually succeed and those who burn out in trading isn't intelligence, education, or even capital—it's the ability to recognize, understand, and manage the complex web of emotions that influences every trading decision.
You’re Capable: One Step Forward Is Progress
Maybe you need this today: You’ve got this. You can do this. You’re strong. You’re capable. One more step in the right direction is progress. Sincerely A Psychologist
Observations Show Universe Is Flat Despite Einstein’s Curvature Possibilities
Einstein showed space can curve, but data reveals a flat Universe According to Einstein, space can take on any curvature depending on what's in it: positive curvature, negative curvature, or zero (flat) curvature. So why is our Universe so flat? https://t.co/fyjYOnXs1d

Hoppers and Super Mario Galaxy Boost Box Office
Between Hoppers and the Super Mario Galaxy Movie, the box office should be doing alright https://t.co/Kb0Rh7NdVs

AI + Chemistry Boosts Bio‑Oil Yield Predictions
Thrilled to share that I’m a co-author of a newly published paper in Scientific Reports — a Nature Portfolio, Q1-ranked journal — highlighting the power of AI-driven innovation in sustainable energy systems. Our paper, “Deep learning enhanced prediction framework for bio...
Mars Missions Hinge on 26‑month Launch Windows
𝗠𝗮𝗿𝘀 𝗶𝘀𝗻’𝘁 𝗷𝘂𝘀𝘁 𝗮𝗯𝗼𝘂𝘁 𝗯𝗶𝗴𝗴𝗲𝗿 𝗿𝗼𝗰𝗸𝗲𝘁𝘀. 𝗜𝘁’𝘀 𝗮𝗯𝗼𝘂𝘁 𝘁𝗶𝗺𝗶𝗻𝗴. One thing that always fascinates me about space missions is this: SpaceX’s Starship does not fly to Mars in a straight line. It follows a Hohmann transfer orbit, an elliptical path around the Sun that...

Non‑local Fatigue Stems From Central Nervous System Fatigue
Non-local fatigue is closely associated with reductions in voluntary activation of the untrained limb, indicating that it is caused by central nervous system fatigue mechanisms. https://t.co/BSr0Cw5Qz6

Productivity Isn't Pretty; It's Messy, Focused, Uncomfortable
We’ve all been there… organizing, rearranging, tweaking systems, making everything look ✨perfect✨… but nothing actually gets done. It feels productive. It looks productive. But sometimes, it’s just procrastination dressed like it has its life together. Real productivity isn’t pretty. It’s messy, focused, and sometimes...
Controlling People Mirror Our Own Unresolved Issues
Others are mirrors. “Everything that irritates us about others can lead us to an understanding of ourselves.” Carl Jung I see this in the clash of controlling people. Controlling people hate each other.

Daily Puzzles and Chess Sharpen the Mind
How do you keep your mind sharp? Of course, besides the usual activities such as exercises, crosswords, or good brain food. I play puzzles and chess every day, and once in a while, my wife surprises me with a puzzle box. I didn't...

Parenting Expert Endorses “What’s My Baby Thinking?”
Beyond thrilled What’s My Baby Thinking? has been recommended by parenting expert Amy Webb, PhD (known on Instagram as The Thoughtful Parent). Amy says she only recommends baby development books that are research-based, relatable, and answer real questions from parents……so it...
Guard Against Arrogance that Follows Success
All of us need to be on guard against arrogance, which knocks at the door whenever you are successful. —Steve Jobs https://t.co/ySumBVrZQh
Success Demands Consistency, Not Special Talent
Tom Brady: To be successful at anything, the truth is, you do not have to be special. You just have to be what most people aren not: consistent, determined and willing to work for it. No shortcuts. https://t.co/OHfLxo1q1M

Denim’s Timeless Appeal: Finding Your Perfect Pair
Through every trend cycle, every silhouette shift, every new must-have moment, jeans remain the one thing we come back to. This week on Substack I’m sharing a few notes on denim, from the editor’s advice I was given early in my...

Nvidia Launches Orbital AI Chip to Bypass Earth’s Energy Limits
Nvidia announces Vera Rubin Space-1 chip system for orbital AI data centers “Orbital data centers have been an increasingly popular proposition as AI demand tests Earth's energy constraints.” https://t.co/fWrKyLiAij #SpaceEconomy https://t.co/SBqD6vmYbz

Czech SF Anthology Delivers Vampire and Hard‑SF Gems
I read about half of “21st‑Century Czech SF Short Stories” on the plane. So far, my favorites are the vampire-themed “You Only Live Once” and the hard‑SF piece “Melting Point.” https://t.co/lswf3WuUCs

Build Kids' Confidence Through Responsibility, Not Praise
Confidence isn’t built by praise. It’s built by responsibility. Daily builders: • Small tasks • Problem-solving • Encouragement, not rescue Keep this as a parenting reminder. #BuildConfidence #PositiveParenting #RaisingStrongKids #MomTips #IndianParents
Prioritize Eulogy Virtues Over Résumé Skills for True Fulfillment
“It occurred to me that there were two sets of virtues, the résumé virtues and the eulogy virtues. The résumé virtues are the skills you bring to the marketplace. The eulogy virtues are the ones that are talked about at...
Sagan Warned Congress: Climate Change Escalates Exponentially
If you haven’t watched this before, you should. The brilliant Carl Sagan testifying before the United States Congress in 1985 on #ClimateChange. We should have listened then. Will we now? Climate change isn’t an on & off switch. It’s an exponential dial....

Essential Insights for Every Working Professional
This book is packed with great insights and is a must read for any working professional.
Great Results Come From Sweat, Not Just Inspiration
Jeff is a former athlete so he know that building something great is 99% perspiration. The 1% inspiration is the easy & fun part.

Father‑Son Enjoy Early Project Hail Mary Screening
Discovered there was an early screening tonight of Project Hail Mary about 20 minutes from home. My son and I snagged tickets and thoroughly enjoyed it. Two thumbs down. #projecthailmary https://t.co/Klmb3XsAMP
Exploring Known and Unknowns in NAD Coenzyme Research
looking forward to concluding next week's NAD for Health conference in Copenhagen with a talk on Known Knowns and Known Unknowns in NAD Coenzyme Research.... see you there https://t.co/hLAnAq7Fay
Kindness: The Secret Longevity Prescription
Kindness is a powerful longevity drug. There is a steep mental cost to undue negativity and cruelty; if left untreated will manifest in very physical stress. If you wish to live long, live with kindness and love as pillars of your...
End Your Nightmare in 60 Seconds for Real Relief
If you wake up from a stressful dream, don’t just scroll your phone and try to forget it. Take like 60 seconds and imagine how the dream ends. Give it a resolution. Your brain literally cannot tell the difference between...

Magic vs Psychology Reflects Ego, Not Primary Consciousness
Magic vs psychology is a modern parse. It is of ego consciousness, not primary consciousness. https://t.co/5GQcFWxsFm

Too Much Introspection Stalls Progress; Act Forward
David Senra: You don't have any levels of introspection? Marc Andreessen: Yes, zero. As little as possible. David: Why? Marc: Move forward. Go! I found people who dwell in the past get stuck in the past. It's a real problem and it's...
Romcom “BASIC” Unpacks Social Media’s Love Complications
Over on @Variety, I reviewed chelseadevantez’s BASIC - and fell head over heels for this romcom about the complexities that arise in our relationships with social media and romances. Ashley Park and Leighton Meester are absolutely terrific. My SXSW review:...
Day 1 Highlights From APS Global Physics Summit
🧪⚛️ A brief write-up of random highlights from Day 1 of the big annual APS Global Physics Summit (formerly known as the March Meeting). https://t.co/tO5dvFZm3Q

Why Vintage Curved Watches Still Defy Wrist Shape
Really into the idea of buying a vintage curved case watch. Specifically something rectangular and dressy Honestly don’t know why more watches aren’t shaped this way—which is to say, shaped like your actual wrist https://t.co/ShZQXPJiZ7
Learning Is Cheap—Never Too Late to Switch Careers
Something to be extremely grateful for living today: The cost of skill acquisition or career switching is incredibly low. This means that for almost anything, it is never too late. We have access to so much, and have so much technology to leverage...
Innovation Cuts Renovation Strain, Who’s Next?
#WhosNext? Renovation assistants? #Innovation of many kinds have helped reduce the strain of renovation work. (GiGadgets) https://t.co/1dkKK2w9un
Hasui Kawase’s Vintage Woodblocks Celebrate Moonlit Trees
Of trees, tenderness, and the Moon – the gorgeous vintage woodblocks of Japanese artist Hasui Kawase https://t.co/6dPkjlpTEt
Is Your Inner Sense Hijacked by External Surveillance?
Therapy question: Is your interoception working properly or has it been conscripted since childhood into an outward-facing surveillance system?

Focus on Process, Not Outcome: Performance Starts Here
Most people want the outcome. But coaching keeps teaching the same lesson: You cannot perform the outcome. Only the rep in front of you. That is why I keep coming back to this: Process > Progression > Progress > Outcome Process is where performance...
Coherence, Not Ambition, Is the Key to Better Life
Things that actually build a better life Better sleep. Lower noise. One clear goal. One clear offer. Protected attention. Daily movement. Cleaner relationships. Most people do not need more ambition. They need more coherence.

Absolute Certainty Freezes Your Intelligence
Those who are absolutely sure of everything have put their Intelligence in cold storage. #SadhguruQuotes https://t.co/wHlcGToV7n
Oscar Short Film Tie Highlights Tiny Voting Body
For only the seventh time in Academy history, a category ended in a tie...best live-action short film. One studio executive joked to @Variety in the lobby, “If you needed any other proof that only 200 people vote in the shorts,...

Neurodivergent Sleep Issues Are Biological, Not Personal Failing
If you have ADHD or autism, your sleep struggles are not in your head and they are not a character flaw. Your nervous system is wired differently. That changes everything about how you sleep. Comment CALM NIGHTS and I'll send you the...
Fear of Replaceability Sabotages Leadership, Not Ambition
If you secretly think slowing down will expose you as replaceable— that’s not ambition. You’re afraid, and that fear is running your leadership, and ruining your life.

Busboys Trailer Delivers Hilarious Duo David Spade, Theo Von
Funny Trailer for 'Busboys' Comedy with David Spade and Theo Von https://t.co/nvhHyJkvuB #BusBoys #TheoVon #DavidSpace #comedy https://t.co/c68BGwXeRX
Late‑Night Moms Reveal Their Quiet‑Hour Projects
Calling all Late Night Moms 🌙 What do you work on after the house goes quiet? (I’ll go first — drop yours below 👇)

Vote for the Top Engineered Yeast Bioart
It’s time for the annual vote for best engineered yeast bioart from the @ImperialBioeng undergrad #SynBio students. Help us decide among these beautiful final 4 with your votes. 🗳️ ⬇️ https://t.co/2fo1XaGCmL