Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves first CIRM‑funded gene‑editing therapy for rare immune disorder
The FDA has granted approval to KRESLADI, a gene‑editing therapy from Rocket Pharmaceuticals that treats severe leukocyte adhesion deficiency‑I in children without a matching bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine (CIRM), highlighting the agency’s impact on translational research.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
Gerald Kuo argues that traditional health‑care metrics, such as blood pressure or lab values, fail to capture what matters most to older adults—functional independence and mobility. He uses a sub‑Riemannian geometry metaphor to illustrate how aging imposes constrained pathways that require more than medication, emphasizing the combined role of exercise, nutrition, and community support. The piece critiques the system’s focus on hospitals and diagnostics while calling for greater investment in community‑based programs and integrated care models. Kuo also highlights the potential of AI to streamline multidisciplinary coordination for elder care.
A recent commentary highlights that many medical practices remain closed roughly 75% of the time, limiting patient access to urgent care. While a few specialists, such as retina surgeons, maintain after‑hours capabilities for critical cases, most offices cannot provide immediate...
Researchers published a longitudinal study showing that people living with HIV who switch from daily oral antiretrovirals to the long‑acting injectable combo cabotegravir‑rilpivirine experience an early, transient rise in monocyte activation followed by a sustained decline below baseline levels. Flow...
A false accusation can instantly derail a physician’s career, leading to suspension, loss of referrals, and lasting reputational damage before any court ruling. The article highlights how media narratives and regulatory hindsight often cement the stigma, even when doctors are...
Mobile crisis teams are proving effective at de‑escalating psychiatric emergencies, with Bozeman, Montana’s unit cutting police mental‑health call time by nearly 80% and averting unnecessary ER visits. Across the United States, at least 1,800 teams operate, yet most rely on...
The UK government, under Labour’s Wes Streeting, has launched an independent review into mental health conditions, ADHD and autism across all ages. The terms of reference call for an evidence‑backed analysis of prevalence, trends, medicalisation, and the role of both...
Dr. Shayan Rab became Los Angeles County’s first full‑time street psychiatrist and helped launch the HOME (Homeless Outreach and Mobile Engagement) Team, the inaugural model that embeds street psychiatry within the county’s field‑based mental‑health services. The multidisciplinary team blends community...
Medical training in the United States still lacks formal instruction on communicating with tracheostomy patients, despite more than 100,000 procedures performed annually. Clinicians often encounter patients who cannot speak, leading to isolation, depression, and anxiety. Individualized communication plans—considering literacy, physical...
Dental anxiety remains a pervasive barrier that drives patients to postpone or avoid dental visits, often resulting in advanced oral disease. The fear typically originates in early experiences and escalates into a cycle of avoidance and more invasive treatments. Modern...
Professor Prokar Dasgupta, a leading robotic urological surgeon, performed the UK’s first long‑distance robotic prostate removal from London on a 62‑year‑old patient in Gibraltar, 1,500 miles away. The operation was conducted via a remote robotic platform that gave the surgeon...
Opioid overdoses, long associated with humans, are now recognized as a threat to dogs, especially as fentanyl and other potent opioids proliferate in Canadian communities. Veterinary and law‑enforcement reports show dogs can inhale, ingest, or absorb opioids, and naloxone—available without...
During a congressional hearing, neurologists warned that rare disease patients are dying while therapies linger in FDA review. The FDA recently rejected the SCA drug troriluzole, demanding more statistical certainty despite trial data showing over 50% fall‑risk reduction. Congress has...
A 2018 FDA Class II recall of the LINX Reflux Management System failed to remove the device from hospital inventories, leading to implants months after the notice. Lawsuits filed in 2026 allege that recalled implants remained in stock and were used...
Clinical trials have long relied on site‑based recruitment, leaving under‑ and misdiagnosed patients underrepresented. Recent studies show digital outreach can identify symptomatic individuals who never enter traditional healthcare pathways, dramatically expanding the eligible pool. Digital campaigns have cut cost per...
A recent headline about a 7‑year‑old dying from a brain condition sparked parental alarm. The condition, Subacute Sclerosing Panencephalitis (SSPE), is a rare, progressive neurological disease that can emerge years after a measles infection. SSPE affects roughly one in a...
The 340B drug‑pricing program now saves covered entities an estimated $44‑54 billion annually, but its rapid expansion has turned compliance into a complex, data‑intensive operation. Since the Affordable Care Act and the 2020 manufacturer restrictions, hospitals manage hundreds of contract pharmacies,...
The healthcare sector faces soaring costs, workforce gaps, and fragmented data, prompting a shift toward AI-driven solutions. Machine learning, NLP, computer vision, RPA, and generative AI are emerging as core technologies that improve diagnostics, streamline operations, and personalize treatment. A...
A multi‑center mixed‑method study published in Pediatric Research maps the full pathway from early autism detection to diagnosis and intervention. Researchers found wide variation in care efficiency, with many families facing prolonged waits, fragmented communication, and limited specialist access. Parental...
What happens when a physician becomes the victim of medical gaslighting? They almost die. In a recent episode of The Podcast by KevinMD, neurologist Dr. Carolyn Larkin Taylor shared a story that exposes a massive crack in our medical system. Dr. Taylor...
The Ferndale Fire Department in Montana earned Quick Response Unit certification on Feb. 13, allowing its volunteers to answer medical emergencies directly. The new status cut response times by roughly ten minutes, as demonstrated when EMTs arrived before the Bigfork ambulance...
A new study by Ozcifci et al. introduces modified stress scores that combine glucose, lactate, blood‑pressure variability, and C‑reactive protein to assess peri‑operative stress in pediatric cardiac surgery. These composite indices demonstrated significantly higher predictive accuracy for adverse outcomes such...
Melatonin has become a ubiquitous over‑the‑counter sleep aid for children, driven by parental demand for quick, natural‑appearing solutions. A recent Boston Children’s Hospital review confirms strong short‑term efficacy for kids with autism or ADHD, but finds scant long‑term safety data...
The author recounts his stint as a general practitioner at a Qatari visa centre in India, where doctors screened migrant laborers for health risks before they could work in Qatar. He reflects on the broader context of Qatar's labor practices,...
Hong Kong’s Health Secretary Lo Chung‑mau announced that under‑performing members of the volunteer Medical Council will be replaced rather than punished, as part of an amendment to the Medical Registration Ordinance. The reform avoids imposing rigid deadlines, instead requiring the...
Transcutaneous carbon dioxide (tcCO₂) monitoring is emerging as a viable alternative to arterial blood gases and end‑tidal CO₂ in neonatal and pediatric intensive care. Recent Pediatric Research data show a strong correlation between tcCO₂ readings and PaCO₂ in stable patients,...
Ontario’s health‑care system was designed for a stable, predictable era, but today it faces structural deficits driven by rapid demographic change, chronic disease growth, and constrained funding. The model’s emphasis on efficiency over resilience has left hospitals operating at full...
A new national‑cohort study published in BMC Geriatrics links the quality of childhood friendships to frailty in older adults, showing that early‑life social deprivation combined with adult social isolation dramatically raises frailty scores. Researchers tracked thousands from school age to...
More than 42 million Americans carry HPV, a leading cause of cervical cancer, prompting heightened public‑health concern. Dr. Dana Cohen outlines three holistic interventions—immune‑supporting nutrition, adequate hydration, and stress reduction—to lower HPV persistence and cancer risk. She highlights medicinal mushrooms, vitamin C,...
Australian tech enthusiast Paul Conyngham used ChatGPT and AlphaFold to design a personalized mRNA vaccine for his dog Rose, whose tumor was genetically sequenced at UNSW. The AI‑assisted workflow identified mutations and suggested therapeutic targets, enabling a custom vaccine administered...
A retrospective case series of four patients undergoing intradural spinal tumor resection evaluated multimodal intraoperative neuromonitoring (IONM). The study tracked motor evoked potentials, somatosensory evoked potentials, and D‑wave signals, noting transient MEP changes in three cases. Preservation or recovery of...
Eli Lilly has launched Employer Connect, a platform that lets large employers purchase its weight‑loss injection Zepbound at a discounted $449 price, aiming to close the coverage gap that leaves over half of workers without obesity drug benefits. The program bypasses...
Actor Akshay Kumar opened up at the India Today Conclave about losing his father to prostate cancer at age 67, using the personal tragedy to spotlight prostate health. He highlighted that his family was unaware of the need for regular...
I mean…(allegedly) the hospital executives at a local Childrens hospital got $250k BONUSES each. It’s a nonprofit hospital. Many nonprofit hospital executives get paid millions a year. I guess the numbers just don’t shock me anymore.
A short video of a man picking up his wife a Dr who just completed 36 hours of straight call prompted netizens to urge KKM to improve working conditions. It reminded me of my housemanship days way back in 1990 in...
Japan has become the first country to grant conditional approval for two regenerative medicines that use induced pluripotent stem cells—AMCHEPRY for Parkinson’s disease and RiHEART for severe heart failure. The Parkinson’s therapy implants dopamine‑producing neurons into the brain, while the...
Researchers analyzing over 30 million adverse‑event reports found that patients using Wegovy, the high‑dose semaglutide injection for obesity, have about five times the odds of developing ischemic optic neuropathy (ION) compared with those on Ozempic, the lower‑dose diabetes formulation. The association...
Researchers funded by the NIH have created an AI‑driven clinical decision support tool that predicts intimate partner violence (IPV) risk using both structured health records and unstructured medical notes. In a study of 850 IPV cases and 5,200 matched controls,...
Malaysia’s National Anti‑Drug Agency reported that 191,832 individuals received treatment in 2025, a marginal 0.5 percent dip from the previous year’s 192,857. While the overall figure suggests a modest improvement, the data spans all age brackets and reflects the continued scale...
I teach medical students about neurodegeneration. But a new clinical trial shows the most powerful brain drug might be free. Researchers at AdventHealth put 130 adults (ages 26-58) through a randomized controlled trial: 150 minutes of aerobic exercise per week vs....
South Korean architects Shin Yeon Ho and Mo Byeong Guk unveiled the Reach Hospital Lounge, an 83 m² patient‑centric space at Rich Oriental Hospital slated for 2025. The design employs high ceilings, a diagonal ceiling plane, and floating furniture to create...
Surgeon General nominee Casey Means clarified she supports the measles vaccine, aligning with Dr. Oz and CDC guidance after earlier criticism for avoiding a direct endorsement. The CDC has recorded 1,362 measles cases across 31 states, with a South Carolina...
The “root cause” is a dysregulated appetite with a terrible environment. The GLP-1 normalizes the dysregulated appetite and allows for navigation of the environment.
Our new @NatureMedicine paper proposing a path for better, dynamic evaluation of large language models for patient care https://t.co/VHvyxDFKuc CES-clinical environment simulator @pranavrajpurkar https://t.co/Q9tyeupEk3
![Wellness Requires Safe Spaces Outside the Medical System [PODCAST]](/cdn-cgi/image/width=1200,quality=75,format=auto,fit=cover/https://kevinmd.com/wp-content/uploads/Design-2-scaled.jpg)
Hospital‑based wellness committees have become a staple of many health systems, offering yoga sessions, mindfulness workshops, and occasional retreats. While these offerings provide a brief reprieve, they are typically delivered in conference rooms that lack natural light and are populated...
Psilocybin seems to help tobacco smokers quit; Scientists discover a new species of psychedelic mushroom in Africa https://t.co/E5d2aUHoUQ
The Enemy isn't Big Pharma. It's the FDA and Regulators who won't allow you to test experimental therapies on yourself (or your dog). Even if it's life or death.
Preliminary CDC data show influenza vaccine effectiveness fell sharply in the 2025‑2026 season, ranging from 14‑48% in children and 22‑34% in adults. The decline follows the agency’s January decision to stop recommending universal flu shots for all children. Experts cite...
An intriguing case of “exceptional resilience” against dementia A 75-year-old man free of dementia despite a dominant Alzheimer’s mutation — and a possible hint for the rest of us https://t.co/lWn9gCKrEm https://t.co/jq0L2NtZ27
Consumer Reports evaluated 20 hearing‑aid brands across ten categories, gathering feedback from over 13,000 users. The study crowned Philips, Jabra, Rexton, Phonak and Oticon as the top five, highlighting features such as Bluetooth connectivity, AI‑driven noise cancellation and rechargeable batteries....
2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines https://t.co/Jq8Zh6XQlY https://t.co/OFicPSvJuH
