Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
Physician wellness leaders are confronting a hidden paradox: while therapy is increasingly normalized, medication use remains stigmatized. Psychiatrist Jessi Gold, chief wellness officer for the University of Tennessee System, disclosed her 13‑year daily Wellbutrin regimen, revealing the pressure physicians feel to hide pharmacologic treatment. The article argues that this silence reinforces a culture of invulnerability, shaping how trainees perceive professional resilience. By exposing the dissonance between public wellness initiatives and private medication concealment, the piece calls for a more honest, humanized view of physician health.
Researchers conducted a double‑blind, placebo‑controlled trial with 1,000 participants averaging 70 years old, giving half a daily multivitamin (Centrum Silver) and the other half a placebo. After two years, analysis of five epigenetic aging clocks indicated the supplement group aged...
I've covered most of the big controversies the FDA has faced over the past 25 years: Vioxx, drug-coated stents, and Aduhelm all spring to mind. In all of these cases, the FDA's advisory panel system, in which the agency calls together...
Taisho Pharmaceutical’s vornorexant (TS‑142), marketed as Vorzzz®, received Japanese regulatory approval in August 2025 as a dual orexin‑1/2 receptor antagonist for insomnia. The drug distinguishes itself from existing DORAs through rapid absorption and a short elimination half‑life, aiming to minimize...
Indiana University Health’s new downtown Indianapolis hospital, a $2.31 billion, 864‑bed project, is being built using principles from General Stanley McChrystal’s book *Team of Teams*. Vice president Jim Mladucky says traditional hierarchical methods can’t handle the post‑COVID labor shortages, price escalations, and rapid...
Accountable Care Organizations met with congressional staff last week to discuss reforms to the Medicare Access and CHIP Reauthorization Act (MACRA) after a bipartisan request for information was issued. The meeting aimed to explore long‑term solutions for physician payment that...
Researchers at Tokyo University of Science discovered that polyamines, especially spermidine—a compound touted for longevity—can accelerate the growth of cancer cells. Laboratory experiments on cervical and breast cancer lines showed polyamines promote aerobic glycolysis and increase the oncogenic protein eIF5A2....
New Day Healthcare appointed co‑founder and COO Kathy Poland as interim CEO following the death of founder G. Scott Herman. Poland brings decades of home‑based care leadership to guide the organization through a period of transition. New Day, owned by...
ECRI released its 2026 Top 10 Patient Safety Concerns, placing AI diagnostic dilemmas at #1. The report warns that unchecked AI tools can cause missed or incorrect diagnoses due to automation bias and biased training data. Rural healthcare access ranks...
A large JAMA Network Open study of 5,607 chronic kidney disease (CKD) patients found that lower estimated glomerular filtration rate (eGFR) and higher urinary protein‑to‑creatinine ratio (UPCR) significantly raise the risk of cognitive impairment. Each standard‑deviation drop in eGFR increased...
Kyndryl’s Healthcare Readiness Report finds a widening gap between AI ambition and safe, compliant scaling in the sector. While 55% of providers worry about keeping up with evolving regulations, only 30% feel prepared, and 76% have more AI pilots than...
Clifford Thomas lost four relatives, including his mother, to COVID‑19 and vowed to keep his family healthy. In Albany, Georgia, that promise collides with a healthcare landscape dominated by Phoebe Putney Memorial, the city’s sole hospital system. Stringent state Medicaid...
AbbVie announced top‑line Phase 1 multiple ascending‑dose data for its amylin analog ABBV‑295, showing 7.75‑9.79% weight loss after 12 weeks of treatment. The long‑acting compound was administered every other week then monthly, with a favorable tolerability profile and no serious adverse...
A UCSF study evaluated a glaucoma comanagement model where trained optometrists provided routine care and referred to specialists as needed. Over five years, 775 eyes of 391 patients showed comparable stability between a transfer‑care pathway (optometrist only) and an alternate‑care...
Intrascleral secondary IOL fixation demands precise haptic handling to avoid slippage. Agarwal and Narang detail a method where a bisected iris‑hook plug is mounted on a 26‑gauge needle, threaded onto the IOL haptic, and then slid into place to lock...
AbbVie and its partner Gubra released Phase 2 data on a long‑acting amylin analogue that produced significant weight loss in obese participants, with reductions approaching double‑digit percentages and a clean safety signal. The study highlighted dose‑responsive efficacy and tolerability, positioning the...
Verily Life Sciences and Samsung Electronics have announced a partnership to embed the Galaxy Watch 8 into Verily’s precision health platform, PRE. The FDA‑cleared wearable will stream continuous biometric data—such as SpO2, sleep‑apnea scores, and AFib alerts—directly into Verily’s Viewpoint...
The Fullerton Fire Department launched a city‑run ambulance service on Feb 2, hiring 32 operators after receiving over 500 applications. The program began with refurbished ambulances while awaiting seven new units, and it operates three 24‑hour shifts plus an additional 12‑hour...
It's more common than you think. A woman gets a faint positive on a pregnancy test, starts telling family, and then bleeds four days later. This is called a chemical pregnancy. And most OBs will say "it was just a...
At the Winter Clinical Dermatology meeting, UCLA dermatologist April W. Armstrong outlined how clinicians are personalizing atopic dermatitis treatment amid a surge of targeted options. She highlighted that oral JAK inhibitors are chosen for rapid itch control, while IL‑13 biologics...
The traditional fully in‑person outpatient physical‑therapy model is under strain from tighter reimbursement, staffing shortages, and patients demanding more flexible scheduling. Clinics are turning to hybrid care, combining essential hands‑on visits with short virtual check‑ins to maintain outcomes while improving...
Re: Prasad, from this morning's @statnews Readout newsletter: FDA Commissioner Marty Makary is in Miami this week speaking to health care investors attending a slew of broker conferences, noted Mizuho health care strategist Jared Holz. That should make for some...
Max Hodak (@maxhodak_) is the co-founder of Neuralink and founder of @ScienceCorp_, a company building brain-computer interfaces that can restore sight. Science has developed a tiny retinal implant that stimulates cells in the eye to help blind patients see again. More...
Developmental‑behavioral pediatrician Ronald L. Lindsay reflects on a 1998 grant that outlined nine concrete goals to address health disparities for children with neurodevelopmental disabilities, women with disabilities, and underserved families. He argues that his early warnings—now framed as a Cassandra‑type...
GlobalData Healthcare attended the World Evidence, Pricing and Access (EPA) congress in Amsterdam, where industry leaders debated mounting market instability. Sessions focused on the impact of the Most Favored Nation (MFN) policy, shifting US tariffs, rapid AI integration, and the...
In September, President Trump urged pregnant women to avoid Tylenol, echoing Health Secretary Robert F. Kennedy Jr.'s claim of a link between prenatal acetaminophen and autism or ADHD. The FDA responded that no causal relationship has been established, citing mixed...
The National Community Pharmacists Association (NCPA) warns that independent pharmacies are facing a cash‑flow crisis as 67% report Medicare drug‑price negotiation refunds delayed 22 days or more, forcing 60% to dip into personal savings. NCPA is urging the Centers for...
The ACA’s state‑run health‑insurance marketplaces, which require essential benefits and sort plans into Platinum, Gold, Silver and Bronze tiers, covered about 10 million people before COVID‑19. A 2021 expansion of premium tax credits more than doubled enrollment to 23 million and pushed...
Stable GLP‑1 receptor agonists such as Exendin‑4 and Ozempic improve beta‑cell viability by modulating gene expression. Researchers at the Salk Institute discovered that these drugs induce phosphorylation of Med14, a core subunit of the Mediator transcription complex. Phosphorylated Med14 enables...
The Elekta Gamma Knife Esprit, featuring 192 simultaneous beams and millimeter‑level precision, is cementing radiosurgery as a first‑line therapy for brain tumors, vascular lesions, and emerging functional disorders. Advances in high‑resolution MRI, functional imaging, and AI‑driven contouring have streamlined planning and...
Veterans Affairs’ homegrown VistA electronic health record, praised for usability and clinical outcomes, was replaced by Cerner’s commercial Millennium platform through a sole‑source $10 billion contract. The transition has ballooned to an estimated $37‑$50 billion, far exceeding the roughly $2 billion that modernizing...
VisualVault, a digital information management firm, will exhibit at HIMSS Global Health Conference 2026 in Las Vegas from March 9‑12, occupying booth 6424 in the Carahsoft Pavilion. The company will highlight a suite of solutions—including Digital Patient Intake, AI‑Enabled Document Workflow, Legacy Data Archive,...
Physicians are more likely to choose intensive blood‑pressure targets for elderly patients when digital health data—home BP readings and wearable mobility metrics—are available. A discrete choice experiment with 197 Australian doctors showed an odds ratio of 2.7 for intensive treatment...
Bristol Myers Squibb announced that its oral CELMoD candidate mezigdomide met primary endpoints in the Phase 3 SUCCESSOR‑2 trial for relapsed or refractory multiple myeloma. The open‑label study showed a statistically significant improvement in progression‑free survival compared with the current standard...
A prospective cohort of 98,261 U.S. veterans with type 2 diabetes found that each additional healthy lifestyle habit—such as a plant‑based diet, regular exercise, non‑smoking, adequate sleep, and stress management—significantly lowered the risk of major cardiovascular events. Participants reporting all eight...
Researchers analyzing nearly 30,000 Swedish women aged 15‑24 with prior cervical high‑grade squamous intraepithelial lesion (HSIL) found a markedly elevated risk of cardiovascular disease compared with over 149,000 matched controls. Hazard ratios indicated a 20% increase in overall CVD, with...
Healthcare employers are facing heightened labor activity, especially in unionized hospitals across the Northeast and New York City, prompting concerns over staffing ratios, wages, and broader workforce strategy. Littler Law is hosting a webinar on April 16, 2026, to dissect...
Bausch + Lomb announced the kickoff of an R&D “Teach‑in” webinar series, beginning with a March 23 session focused on its glaucoma pipeline. Executive Vice President of R&D Yehia Hashad and senior leaders will discuss ELios™, an implant‑free laser glaucoma surgery already launched in...
The NIHR has granted £2.31 million to 24 projects developing technology‑assisted solutions that stop a single chronic condition from evolving into multi‑morbidity. The funding, delivered via the i4i FAST programme, targets virtual rehabilitation, AI‑driven diagnostics, home monitoring devices and digital self‑management...
Dr. Francisco M. Torres recounts an unexpected encounter with a world‑famous patient who arrived under his legal name, leaving the staff oblivious to his celebrity status. The revelation sparked a flurry of excitement among clinic personnel, yet the physician maintained...
The new Huberman Lab episode is out: Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex Marson 0:00 Alex Marson 2:21 Diseases & Current Biological Landscape; AI & Computational Tools 5:56 Immune System, Innate vs Adaptive Immune System 10:55 Thymus, T...
Just published @NatureMedicine A daily multivitamin (MVM) slowed epigenetic aging in a randomized trial after 2 years; effect was small (~2 months) and not seen with cocoa extract supplement (vitamin was Centrum Silver) https://t.co/snOMNsTzW7 https://t.co/a6MhMuRhJb
HeartBeam Inc. announced that its executive team will attend three major investor and industry conferences in March 2026, including Oppenheimer’s virtual MedTech summit, the ROTH conference, and the American College of Cardiology’s ACC.26. The CEO and CFO will present a...
After a UnitedHealth Group takeover prompted a physician exodus & turmoil for patients, Oregon lawmakers sought to rein in corporate health care. Now, the new law is facing an early test. https://t.co/ABNLPXk5US via @statnews
We’re excited to introduce the 2026 Innovators You Need to Know at #HIMSS26! 📍Stop by Booth #6453 Scan QR codes for exclusive insights, guides, and resources… every scan gives you a chance to win prizes.🤩 Start exploring now, or see it in person:...
Researchers reported in Nature Communications that early pregnancy prevents the accumulation of a novel hybrid mammary cell type in mice. These cells, which produce the inflammatory cytokine IL33, increase with age in never‑pregnant females and are linked to tissue changes...
Appropriate critique of Utah going with AI for prescriptions based on a @Doctronic preprint written by the company, by @JosephSakran gift link https://t.co/HcFqBy86wb https://t.co/QpVA7HGjRT
Pulse Biosciences reported long‑term results from its first‑in‑human nPulse Vybrance study, showing an average 74% reduction in benign thyroid nodule volume after 15‑22 months. The data, presented at the 2026 North American Society for Interventional Thyroidology meeting, revealed no nodule...
Bristol Myers Squibb reported positive interim Phase 3 results from the SUCCESSOR‑2 study, showing that oral mezigdomide combined with carfilzomib and dexamethasone (MeziKd) significantly extended progression‑free survival versus carfilzomib‑dexamethasone alone in relapsed or refractory multiple myeloma. The trial marks the first...
WellSpan Health has opened “Fresh Take Eatery,” a 24/7 AI‑powered robotic kitchen at its York Hospital. The system uses RoboEatz’s Autonomous Robotic Kitchen (ARK) platform with ABB Robotics’ articulated arms, occupying just 400 sq ft. It runs four cooking modules, stores up...
